JP2016515517A5 - - Google Patents
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- JP2016515517A5 JP2016515517A5 JP2016502862A JP2016502862A JP2016515517A5 JP 2016515517 A5 JP2016515517 A5 JP 2016515517A5 JP 2016502862 A JP2016502862 A JP 2016502862A JP 2016502862 A JP2016502862 A JP 2016502862A JP 2016515517 A5 JP2016515517 A5 JP 2016515517A5
- Authority
- JP
- Japan
- Prior art keywords
- active ingredient
- dispersed phase
- solvent
- filtering
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000004480 active ingredient Substances 0.000 claims description 26
- 239000000203 mixture Substances 0.000 claims description 18
- 238000001914 filtration Methods 0.000 claims description 13
- 239000004005 microsphere Substances 0.000 claims description 12
- 238000004519 manufacturing process Methods 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 10
- 229920000642 polymer Polymers 0.000 claims description 10
- 238000009472 formulation Methods 0.000 claims description 9
- 239000002904 solvent Substances 0.000 claims description 9
- 230000001954 sterilising effect Effects 0.000 claims description 8
- 230000002209 hydrophobic effect Effects 0.000 claims description 7
- 238000004659 sterilization and disinfection Methods 0.000 claims description 6
- 238000013268 sustained release Methods 0.000 claims description 6
- 239000012730 sustained-release form Substances 0.000 claims description 6
- UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical group C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 claims description 4
- 229960002537 betamethasone Drugs 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 3
- 230000000855 fungicidal effect Effects 0.000 claims 1
- 230000000975 bioactive effect Effects 0.000 description 4
- 239000004615 ingredient Substances 0.000 description 4
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361790554P | 2013-03-15 | 2013-03-15 | |
| US61/790,554 | 2013-03-15 | ||
| PCT/US2014/028657 WO2014144309A1 (en) | 2013-03-15 | 2014-03-14 | Sustained release microspheres and method of producing the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019080106A Division JP6808777B2 (ja) | 2013-03-15 | 2019-04-19 | 徐放性ミクロスフェア及びその製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016515517A JP2016515517A (ja) | 2016-05-30 |
| JP2016515517A5 true JP2016515517A5 (enExample) | 2018-11-22 |
Family
ID=51537672
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502862A Pending JP2016515517A (ja) | 2013-03-15 | 2014-03-14 | 徐放性ミクロスフェア及びその製造方法 |
| JP2019080106A Active JP6808777B2 (ja) | 2013-03-15 | 2019-04-19 | 徐放性ミクロスフェア及びその製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019080106A Active JP6808777B2 (ja) | 2013-03-15 | 2019-04-19 | 徐放性ミクロスフェア及びその製造方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9956177B2 (enExample) |
| EP (1) | EP2968184B1 (enExample) |
| JP (2) | JP2016515517A (enExample) |
| CN (1) | CN105705141B (enExample) |
| CA (1) | CA2909303C (enExample) |
| ES (1) | ES2697696T3 (enExample) |
| MX (1) | MX362187B (enExample) |
| WO (1) | WO2014144309A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014144309A1 (en) | 2013-03-15 | 2014-09-18 | Oakwood Laboratories | Sustained release microspheres and method of producing the same |
| CN113766952B (zh) * | 2019-03-29 | 2023-09-08 | 国立研究开发法人量子科学技术研究开发机构 | 放射性药品的制造方法及放射性药品 |
| JP2023551508A (ja) * | 2020-11-30 | 2023-12-08 | エルジー・ケム・リミテッド | カスパーゼ阻害剤を含有する注射用組成物及びその製造方法 |
| US11992559B2 (en) | 2021-02-24 | 2024-05-28 | Oakwood Laboratories, Llc | Microsphere formulations comprising lurasidone and methods for making and using the same |
| US20240148662A1 (en) * | 2021-03-11 | 2024-05-09 | Oakwood Laboratories, Llc | Methods and systems for making polymer microspheres |
| CN116999412A (zh) * | 2023-08-03 | 2023-11-07 | 四川迈可隆生物科技有限公司 | 一种含有倍他米松药物的缓释微球制剂及其制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5945125A (en) | 1995-02-28 | 1999-08-31 | Temple University | Controlled release tablet |
| US6046187A (en) * | 1996-09-16 | 2000-04-04 | Children's Medical Center Corporation | Formulations and methods for providing prolonged local anesthesia |
| SE9704186D0 (sv) * | 1997-11-14 | 1997-11-14 | Astra Ab | New composition of matter |
| US6270802B1 (en) | 1998-10-28 | 2001-08-07 | Oakwood Laboratories L.L.C. | Method and apparatus for formulating microspheres and microcapsules |
| WO2002078673A1 (fr) * | 2001-03-29 | 2002-10-10 | Takeda Chemical Industries, Ltd. | Procede de production d'un medicament sous forme de granules fins |
| JP2002356419A (ja) * | 2001-03-29 | 2002-12-13 | Takeda Chem Ind Ltd | 微粒薬物の製造法 |
| US20050260272A1 (en) * | 2004-05-05 | 2005-11-24 | Alkermes Controlled Therapeutics, Inc. | Method of forming microparticles that include a bisphosphonate and a polymer |
| GB2461186B (en) | 2008-04-21 | 2010-09-01 | Otonomy Inc | Controlled release corticosteroid compositions and methods for the treatment of otic disorders |
| US20100086596A1 (en) * | 2008-10-06 | 2010-04-08 | Oakwood Laboratories LLC | Microspheres for releasing an octreotide compound without an initial time lag |
| US8343498B2 (en) * | 2008-10-12 | 2013-01-01 | Massachusetts Institute Of Technology | Adjuvant incorporation in immunonanotherapeutics |
| UA111162C2 (uk) * | 2010-08-04 | 2016-04-11 | Флекшен Терап'Ютікс, Інк. | Ін'єкційна композиція ацетоніду триамцинолону для лікування болю |
| US8708159B2 (en) * | 2011-02-16 | 2014-04-29 | Oakwood Laboratories, Llc | Manufacture of microspheres using a hydrocyclone |
| WO2014144309A1 (en) | 2013-03-15 | 2014-09-18 | Oakwood Laboratories | Sustained release microspheres and method of producing the same |
-
2014
- 2014-03-14 WO PCT/US2014/028657 patent/WO2014144309A1/en not_active Ceased
- 2014-03-14 JP JP2016502862A patent/JP2016515517A/ja active Pending
- 2014-03-14 CA CA2909303A patent/CA2909303C/en active Active
- 2014-03-14 ES ES14762738T patent/ES2697696T3/es active Active
- 2014-03-14 EP EP14762738.4A patent/EP2968184B1/en active Active
- 2014-03-14 US US14/774,851 patent/US9956177B2/en active Active
- 2014-03-14 CN CN201480016260.6A patent/CN105705141B/zh active Active
- 2014-03-14 MX MX2015012231A patent/MX362187B/es active IP Right Grant
-
2019
- 2019-04-19 JP JP2019080106A patent/JP6808777B2/ja active Active
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