JP2016511281A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016511281A5 JP2016511281A5 JP2015562366A JP2015562366A JP2016511281A5 JP 2016511281 A5 JP2016511281 A5 JP 2016511281A5 JP 2015562366 A JP2015562366 A JP 2015562366A JP 2015562366 A JP2015562366 A JP 2015562366A JP 2016511281 A5 JP2016511281 A5 JP 2016511281A5
- Authority
- JP
- Japan
- Prior art keywords
- erythro
- benzoyl
- under conditions
- conditions effective
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361801641P | 2013-03-15 | 2013-03-15 | |
| US61/801,641 | 2013-03-15 | ||
| EP13306056.6 | 2013-07-23 | ||
| EP13306056 | 2013-07-23 | ||
| PCT/IB2014/000494 WO2014140787A2 (en) | 2013-03-15 | 2014-03-14 | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018117808A Division JP2018168171A (ja) | 2013-03-15 | 2018-06-21 | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016511281A JP2016511281A (ja) | 2016-04-14 |
| JP2016511281A5 true JP2016511281A5 (enExample) | 2017-02-02 |
| JP6438417B2 JP6438417B2 (ja) | 2018-12-12 |
Family
ID=51538203
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562366A Active JP6438417B2 (ja) | 2013-03-15 | 2014-03-14 | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
| JP2018117808A Pending JP2018168171A (ja) | 2013-03-15 | 2018-06-21 | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018117808A Pending JP2018168171A (ja) | 2013-03-15 | 2018-06-21 | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US20140316154A1 (enExample) |
| EP (3) | EP3842443B1 (enExample) |
| JP (2) | JP6438417B2 (enExample) |
| KR (1) | KR20150132188A (enExample) |
| CN (1) | CN105051051B (enExample) |
| AU (2) | AU2014229638B2 (enExample) |
| BR (1) | BR112015023558A2 (enExample) |
| CA (1) | CA2900902C (enExample) |
| DK (1) | DK3363805T3 (enExample) |
| ES (1) | ES3017659T3 (enExample) |
| HK (1) | HK1214266A1 (enExample) |
| MX (1) | MX387128B (enExample) |
| PH (1) | PH12015501835B1 (enExample) |
| SG (2) | SG11201506456VA (enExample) |
| WO (1) | WO2014140787A2 (enExample) |
| ZA (1) | ZA201505860B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2396017T3 (en) | 2009-02-16 | 2015-09-14 | Cerenis Therapeutics Holding Sa | Apolipoprotein A-I-mimetika |
| SG189019A1 (en) | 2010-10-18 | 2013-05-31 | Cerenis Therapeutics Holding Sa | Compounds, compositions and methods useful for cholesterol mobilisation |
| CN105051051B (zh) | 2013-03-15 | 2021-07-16 | 萨瑞斯治疗控股公司 | 用于合成神经鞘磷脂和二氢神经鞘磷脂的方法 |
| US9708354B2 (en) | 2013-03-15 | 2017-07-18 | Cerenis Therapeutics Holding Sa | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
| TW201919686A (zh) | 2017-08-10 | 2019-06-01 | 法商塞勒尼斯醫療控股公司 | 脫輔基子(apomers) |
| WO2019030574A1 (en) | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding | Cargomers |
| US20210017202A1 (en) * | 2018-03-27 | 2021-01-21 | Nof Corporation | Sphingomyelin-derived lipid and method for producing same |
| JP7303618B2 (ja) * | 2018-10-05 | 2023-07-05 | 日本精化株式会社 | スフィンゴリン脂質前駆体及びその製造方法、並びに、スフィンゴリン脂質の製造方法 |
| EP4135747A1 (en) | 2020-04-16 | 2023-02-22 | Abionyx Pharma SA | Methods for treating acute conditions using lipid binding protein- based complexes |
| CN115666720A (zh) | 2020-04-16 | 2023-01-31 | 阿比奥尼克斯制药公司 | 用于治疗肾病的cer-001疗法 |
| WO2021209808A1 (en) | 2020-04-16 | 2021-10-21 | Abionyx Pharma Sa | Cer-001 therapy for treating kidney disease |
| JP2023543498A (ja) | 2020-10-01 | 2023-10-16 | アビオニクス ファーマ エスエー | 脂質結合タンパク質ベースの複合体を使用した、眼疾患を治療するための方法 |
| JP2024514154A (ja) | 2021-04-15 | 2024-03-28 | アビオニクス ファーマ エスエー | 臓器保存溶液における脂質結合タンパク質ベースの複合体の使用 |
| EP4504233A1 (en) | 2022-04-06 | 2025-02-12 | Abionyx Pharma SA | Methods for treating leukocytosis, endothelial dysfunction and carditis using lipid binding protein-based complexes |
| EP4504150A1 (en) | 2022-04-06 | 2025-02-12 | Abionyx Pharma SA | Methods for treating eye diseases using lipid binding protein-based complexes |
| EP4536269A2 (en) | 2022-06-10 | 2025-04-16 | Abionyx Pharma SA | Methods for treating acute conditions using lipid binding protein-based complexes |
| CN120344255A (zh) | 2022-06-10 | 2025-07-18 | 阿比奥尼克斯制药公司 | 使用基于脂质结合蛋白的复合物治疗过度炎性病症的方法 |
| IL317896A (en) | 2022-06-28 | 2025-02-01 | Abionyx Pharma Sa | Compounds and processes for the synthesis of sphingomyelins |
| AU2024207875A1 (en) | 2023-01-13 | 2025-07-24 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
| WO2025093929A1 (en) | 2023-10-31 | 2025-05-08 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0146810A3 (de) | 1983-12-05 | 1987-05-13 | Solco Basel AG | Verfahren zur Herstellung von Sphingosinderivaten |
| US5220043A (en) * | 1991-03-21 | 1993-06-15 | Ohio University | Synthesis of D-erythro-sphingomyelins |
| NZ276305A (en) | 1993-11-16 | 1997-10-24 | Depotech Corp | Controlled release vesicle compositions |
| US5766627A (en) | 1993-11-16 | 1998-06-16 | Depotech | Multivescular liposomes with controlled release of encapsulated biologically active substances |
| AU765809B2 (en) * | 1998-02-12 | 2003-10-02 | Emory University | Sphingolipid derivatives and their methods of use |
| JP2004002215A (ja) * | 2002-05-23 | 2004-01-08 | National Institute Of Advanced Industrial & Technology | スフィンゴ脂質誘導体の製造方法 |
| WO2005068480A1 (en) | 2004-01-15 | 2005-07-28 | Biolab Ltd. | Sphingomyelin, intermediates thereof and methods for preparation of same |
| CA2566559C (en) | 2004-05-17 | 2014-05-06 | Inex Pharmaceuticals Corporation | Liposomal formulations comprising dihydrosphingomyelin and methods of use thereof |
| DE602005011802D1 (de) | 2004-06-29 | 2009-01-29 | Jado Technologies Gmbh | Afts |
| JP4825947B2 (ja) | 2004-08-04 | 2011-11-30 | 学校法人関西学院 | 不飽和アミノジオール類の製造方法 |
| JP2006045113A (ja) | 2004-08-04 | 2006-02-16 | Kemikurea:Kk | リン酸エステル類 |
| US8206750B2 (en) | 2005-03-24 | 2012-06-26 | Cerenis Therapeutics Holding S.A. | Charged lipoprotein complexes and their uses |
| US7470664B2 (en) * | 2005-07-20 | 2008-12-30 | Merck & Co., Inc. | HCV NS3 protease inhibitors |
| JP2007204384A (ja) | 2006-01-31 | 2007-08-16 | Kemikurea:Kk | 光学活性リン酸誘導体およびこれを用いた光学活性スフィンゴシン１−リン酸誘導体の製造方法 |
| JP5429734B2 (ja) * | 2007-02-09 | 2014-02-26 | 国立大学法人岐阜大学 | スフィンゴ糖脂質の合成法 |
| JP5178707B2 (ja) | 2007-03-09 | 2013-04-10 | 株式会社糖鎖工学研究所 | スフィンゴシン化合物、その製造方法及びスフィンゴミエリナーゼ阻害剤 |
| AU2009302042A1 (en) | 2008-10-07 | 2010-04-15 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | Liposomal systems comprising sphingomyelin |
| HUE042314T2 (hu) | 2011-02-07 | 2019-06-28 | Cerenis Therapeutics Holding Sa | Lipoprotein komplexek és azok gyártása és alkalmazásai |
| FR3000959B1 (fr) * | 2013-01-14 | 2015-08-21 | Holis Technologies | Nouveaux intermediaires de synthese permettant d'acceder avec de bons rendements a des derives de sphingosines, ceramides et sphingomyelines |
| US9708354B2 (en) | 2013-03-15 | 2017-07-18 | Cerenis Therapeutics Holding Sa | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
| CN105051051B (zh) * | 2013-03-15 | 2021-07-16 | 萨瑞斯治疗控股公司 | 用于合成神经鞘磷脂和二氢神经鞘磷脂的方法 |
-
2014
- 2014-03-14 CN CN201480015700.6A patent/CN105051051B/zh active Active
- 2014-03-14 EP EP20214357.4A patent/EP3842443B1/en active Active
- 2014-03-14 EP EP18160532.0A patent/EP3363805B1/en active Active
- 2014-03-14 MX MX2015012877A patent/MX387128B/es unknown
- 2014-03-14 US US14/213,269 patent/US20140316154A1/en not_active Abandoned
- 2014-03-14 WO PCT/IB2014/000494 patent/WO2014140787A2/en not_active Ceased
- 2014-03-14 CA CA2900902A patent/CA2900902C/en active Active
- 2014-03-14 EP EP14729036.5A patent/EP2970344A2/en not_active Withdrawn
- 2014-03-14 KR KR1020157025911A patent/KR20150132188A/ko not_active Withdrawn
- 2014-03-14 SG SG11201506456VA patent/SG11201506456VA/en unknown
- 2014-03-14 BR BR112015023558A patent/BR112015023558A2/pt not_active Application Discontinuation
- 2014-03-14 DK DK18160532.0T patent/DK3363805T3/da active
- 2014-03-14 AU AU2014229638A patent/AU2014229638B2/en active Active
- 2014-03-14 ES ES20214357T patent/ES3017659T3/es active Active
- 2014-03-14 SG SG10201804887YA patent/SG10201804887YA/en unknown
- 2014-03-14 JP JP2015562366A patent/JP6438417B2/ja active Active
- 2014-03-14 HK HK16102047.1A patent/HK1214266A1/zh unknown
-
2015
- 2015-04-22 US US14/693,520 patent/US9643915B2/en active Active
- 2015-08-14 ZA ZA2015/05860A patent/ZA201505860B/en unknown
- 2015-08-19 PH PH12015501835A patent/PH12015501835B1/en unknown
-
2017
- 2017-04-04 US US15/478,532 patent/US20170204122A1/en not_active Abandoned
-
2018
- 2018-06-21 JP JP2018117808A patent/JP2018168171A/ja active Pending
- 2018-11-21 AU AU2018267598A patent/AU2018267598A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016511281A5 (enExample) | ||
| US9708354B2 (en) | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins | |
| TWI709567B (zh) | 抗病毒核苷酸類似物的製備方法 | |
| US20170204122A1 (en) | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins | |
| JP2012515142A5 (enExample) | ||
| RU2012141048A (ru) | Композиция прокатализатора с замещенным амидоэфиром в качестве внутреннего донора электронов | |
| JP2014530809A5 (enExample) | ||
| EP3077404A2 (en) | Purification of tenofovir alafenamide and its intermediates | |
| RU2015105294A (ru) | Способ получения тенелиглиптина | |
| JP2015527345A5 (enExample) | ||
| EP3805199A4 (en) | PROCESS FOR PREPARATION OF PREGABALIN INTERMEDIATE (R)-3(CARBAMOYLMETHYL)-5-METHYLHEXAID | |
| JP2017515949A5 (enExample) | ||
| CA2812178A1 (en) | Methods for the synthesis of plasmalogens and plasmalogen derivatives, and therapeutic uses thereof | |
| CN105237560A (zh) | 一种lzc696中间体及其合成方法 | |
| EP2970102B1 (en) | An improved process for the synthesis of melphalan and the hydrochloride salt | |
| JP2018536645A5 (enExample) | ||
| JP2012017285A5 (enExample) | ||
| JP2017513885A5 (enExample) | ||
| JP2019526552A5 (enExample) | ||
| RU2005127872A (ru) | Оптически активные соединения бисоксазолина, способ их получения и применение | |
| JP6139694B2 (ja) | ホスホン酸モノマーの調製のためのプロセス | |
| Nieves et al. | Approaches to polyunsaturated sphingolipids: new conformationally restrained analogs with minimal structural modifications | |
| AR081836A1 (es) | Proceso para la produccion de aliskiren, procedimiento para la preparacion de intermediarios para su sintesis y compuestos necesarios para obtener estos ultimos | |
| JP6011999B2 (ja) | アミノ酸イオン液体を用いたｎ−アシルアミノ酸又はｎ−アシルペプチドの製造方法 | |
| CN1871246A (zh) | {2－[(8，9)－二氧代－2，6－二氮杂－双环[5.2.0]－壬－1(7)－烯－2－基]乙基}膦酸及其酯的制备方法 |