JP2016511281A5 - - Google Patents
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- JP2016511281A5 JP2016511281A5 JP2015562366A JP2015562366A JP2016511281A5 JP 2016511281 A5 JP2016511281 A5 JP 2016511281A5 JP 2015562366 A JP2015562366 A JP 2015562366A JP 2015562366 A JP2015562366 A JP 2015562366A JP 2016511281 A5 JP2016511281 A5 JP 2016511281A5
- Authority
- JP
- Japan
- Prior art keywords
- erythro
- benzoyl
- under conditions
- conditions effective
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361801641P | 2013-03-15 | 2013-03-15 | |
| US61/801,641 | 2013-03-15 | ||
| EP13306056.6 | 2013-07-23 | ||
| EP13306056 | 2013-07-23 | ||
| PCT/IB2014/000494 WO2014140787A2 (en) | 2013-03-15 | 2014-03-14 | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018117808A Division JP2018168171A (ja) | 2013-03-15 | 2018-06-21 | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016511281A JP2016511281A (ja) | 2016-04-14 |
| JP2016511281A5 true JP2016511281A5 (enExample) | 2017-02-02 |
| JP6438417B2 JP6438417B2 (ja) | 2018-12-12 |
Family
ID=51538203
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562366A Active JP6438417B2 (ja) | 2013-03-15 | 2014-03-14 | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
| JP2018117808A Pending JP2018168171A (ja) | 2013-03-15 | 2018-06-21 | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018117808A Pending JP2018168171A (ja) | 2013-03-15 | 2018-06-21 | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US20140316154A1 (enExample) |
| EP (3) | EP2970344A2 (enExample) |
| JP (2) | JP6438417B2 (enExample) |
| KR (1) | KR20150132188A (enExample) |
| CN (1) | CN105051051B (enExample) |
| AU (2) | AU2014229638B2 (enExample) |
| BR (1) | BR112015023558A2 (enExample) |
| CA (1) | CA2900902C (enExample) |
| DK (1) | DK3363805T3 (enExample) |
| ES (1) | ES3017659T3 (enExample) |
| HK (1) | HK1214266A1 (enExample) |
| MX (1) | MX387128B (enExample) |
| PH (1) | PH12015501835A1 (enExample) |
| SG (2) | SG11201506456VA (enExample) |
| WO (1) | WO2014140787A2 (enExample) |
| ZA (1) | ZA201505860B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010213568B2 (en) | 2009-02-16 | 2014-11-20 | Cerenis Therapeutics Holding Sa | Apolipoprotein A-I Mimics |
| CN106167483B (zh) | 2010-10-18 | 2019-02-15 | 塞伦尼斯医疗控股有限公司 | 可用于胆固醇动员的化合物、组合物和方法 |
| US9708354B2 (en) | 2013-03-15 | 2017-07-18 | Cerenis Therapeutics Holding Sa | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
| JP6438417B2 (ja) * | 2013-03-15 | 2018-12-12 | セレニス セラピューティクス ホールディング エスアー | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
| WO2019030575A1 (en) | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding | APOMÈRES |
| WO2019030574A1 (en) | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding | Cargomers |
| WO2019189133A1 (ja) * | 2018-03-27 | 2019-10-03 | 日油株式会社 | スフィンゴミエリン誘導脂質およびその製造方法 |
| JP7303618B2 (ja) * | 2018-10-05 | 2023-07-05 | 日本精化株式会社 | スフィンゴリン脂質前駆体及びその製造方法、並びに、スフィンゴリン脂質の製造方法 |
| IL297336A (en) | 2020-04-16 | 2022-12-01 | Abionyx Pharma Sa | Methods for treating acute conditions using lipid binding protein-based complexes |
| CN115666720A (zh) | 2020-04-16 | 2023-01-31 | 阿比奥尼克斯制药公司 | 用于治疗肾病的cer-001疗法 |
| WO2021209808A1 (en) | 2020-04-16 | 2021-10-21 | Abionyx Pharma Sa | Cer-001 therapy for treating kidney disease |
| KR20230079132A (ko) | 2020-10-01 | 2023-06-05 | 아비오닉스 파마 에스에이 | 안질환을 치료하는 데 사용하기 위한 지질 결합 단백질-기반 복합체를 포함하는 조성물 |
| AU2022258815A1 (en) | 2021-04-15 | 2023-10-19 | Abionyx Pharma Sa | Use of lipid binding protein-based complexes in organ preservation solutions |
| KR20240167701A (ko) | 2022-04-06 | 2024-11-27 | 아비오닉스 파마 에스에이 | 지질 결합 단백질-기반 복합체를 사용하여 안질환을 치료하는 방법 |
| CN119317440A (zh) | 2022-04-06 | 2025-01-14 | 阿比奥尼克斯制药公司 | 使用基于脂质结合蛋白的复合物治疗白细胞增多、内皮功能障碍和心脏炎的方法 |
| EP4536269A2 (en) | 2022-06-10 | 2025-04-16 | Abionyx Pharma SA | Methods for treating acute conditions using lipid binding protein-based complexes |
| US20250352613A1 (en) | 2022-06-10 | 2025-11-20 | Stanislas FAGUER | Methods for treating hyperinflammatory conditions using lipid binding protein -based complexes |
| JP2025521721A (ja) | 2022-06-28 | 2025-07-10 | アビオニクス ファーマ エスエー | スフィンゴミエリンの合成のための化合物およびプロセス |
| KR20260010675A (ko) | 2023-01-13 | 2026-01-21 | 아비오닉스 파마 에스에이 | 지질 결합 단백질 분자 치료 |
| WO2025093929A1 (en) | 2023-10-31 | 2025-05-08 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0146810A3 (de) | 1983-12-05 | 1987-05-13 | Solco Basel AG | Verfahren zur Herstellung von Sphingosinderivaten |
| US5220043A (en) * | 1991-03-21 | 1993-06-15 | Ohio University | Synthesis of D-erythro-sphingomyelins |
| JP3002702B2 (ja) | 1993-11-16 | 2000-01-24 | スカイファーム インコーポレーテッド | 活性物質の制御放出を有する小胞 |
| US5766627A (en) | 1993-11-16 | 1998-06-16 | Depotech | Multivescular liposomes with controlled release of encapsulated biologically active substances |
| CA2320117A1 (en) | 1998-02-12 | 1999-08-19 | Emory University | Sphingolipid derivatives and their methods of use |
| JP2004002215A (ja) * | 2002-05-23 | 2004-01-08 | National Institute Of Advanced Industrial & Technology | スフィンゴ脂質誘導体の製造方法 |
| AU2005205245A1 (en) | 2004-01-15 | 2005-07-28 | Biolab Ltd. | Sphingomyelin, intermediates thereof and methods for preparation of same |
| ATE450251T1 (de) | 2004-05-17 | 2009-12-15 | Tekmira Pharmaceuticals Corp | Liposomale formulierungen mit dihydrosphingomyelin und verfahren zu ihrer verwendung |
| AU2005259501A1 (en) | 2004-06-29 | 2006-01-12 | Jado Technologies Gmbh | Sphingolipids against pathological processes in lipid rafts |
| JP4825947B2 (ja) | 2004-08-04 | 2011-11-30 | 学校法人関西学院 | 不飽和アミノジオール類の製造方法 |
| JP2006045113A (ja) | 2004-08-04 | 2006-02-16 | Kemikurea:Kk | リン酸エステル類 |
| US8206750B2 (en) | 2005-03-24 | 2012-06-26 | Cerenis Therapeutics Holding S.A. | Charged lipoprotein complexes and their uses |
| TWI387603B (zh) * | 2005-07-20 | 2013-03-01 | Merck Sharp & Dohme | Ｈｃｖ ｎｓ３蛋白酶抑制劑 |
| JP2007204384A (ja) | 2006-01-31 | 2007-08-16 | Kemikurea:Kk | 光学活性リン酸誘導体およびこれを用いた光学活性スフィンゴシン１−リン酸誘導体の製造方法 |
| WO2008096880A1 (ja) * | 2007-02-09 | 2008-08-14 | Gifu University | スフィンゴ糖脂質の合成法 |
| US8093395B2 (en) | 2007-03-09 | 2012-01-10 | Otsuka Chemical Co., Ltd. | Sphingosine compound, method for producing the same, and sphingomyelinase inhibitor |
| AU2009302042A1 (en) | 2008-10-07 | 2010-04-15 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | Liposomal systems comprising sphingomyelin |
| PT2673296T (pt) | 2011-02-07 | 2019-01-31 | Cerenis Therapeutics Holding Sa | Complexos de lipoproteínas e sua fabricação e utilização |
| FR3000959B1 (fr) * | 2013-01-14 | 2015-08-21 | Holis Technologies | Nouveaux intermediaires de synthese permettant d'acceder avec de bons rendements a des derives de sphingosines, ceramides et sphingomyelines |
| US9708354B2 (en) | 2013-03-15 | 2017-07-18 | Cerenis Therapeutics Holding Sa | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
| JP6438417B2 (ja) | 2013-03-15 | 2018-12-12 | セレニス セラピューティクス ホールディング エスアー | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
-
2014
- 2014-03-14 JP JP2015562366A patent/JP6438417B2/ja active Active
- 2014-03-14 WO PCT/IB2014/000494 patent/WO2014140787A2/en not_active Ceased
- 2014-03-14 SG SG11201506456VA patent/SG11201506456VA/en unknown
- 2014-03-14 CN CN201480015700.6A patent/CN105051051B/zh active Active
- 2014-03-14 DK DK18160532.0T patent/DK3363805T3/da active
- 2014-03-14 US US14/213,269 patent/US20140316154A1/en not_active Abandoned
- 2014-03-14 SG SG10201804887YA patent/SG10201804887YA/en unknown
- 2014-03-14 ES ES20214357T patent/ES3017659T3/es active Active
- 2014-03-14 BR BR112015023558A patent/BR112015023558A2/pt not_active Application Discontinuation
- 2014-03-14 EP EP14729036.5A patent/EP2970344A2/en not_active Withdrawn
- 2014-03-14 MX MX2015012877A patent/MX387128B/es unknown
- 2014-03-14 AU AU2014229638A patent/AU2014229638B2/en active Active
- 2014-03-14 EP EP20214357.4A patent/EP3842443B1/en active Active
- 2014-03-14 CA CA2900902A patent/CA2900902C/en active Active
- 2014-03-14 KR KR1020157025911A patent/KR20150132188A/ko not_active Withdrawn
- 2014-03-14 HK HK16102047.1A patent/HK1214266A1/zh unknown
- 2014-03-14 EP EP18160532.0A patent/EP3363805B1/en active Active
-
2015
- 2015-04-22 US US14/693,520 patent/US9643915B2/en active Active
- 2015-08-14 ZA ZA2015/05860A patent/ZA201505860B/en unknown
- 2015-08-19 PH PH12015501835A patent/PH12015501835A1/en unknown
-
2017
- 2017-04-04 US US15/478,532 patent/US20170204122A1/en not_active Abandoned
-
2018
- 2018-06-21 JP JP2018117808A patent/JP2018168171A/ja active Pending
- 2018-11-21 AU AU2018267598A patent/AU2018267598A1/en not_active Abandoned
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