JP2016510737A5 - - Google Patents

Download PDF

Info

Publication number
JP2016510737A5
JP2016510737A5 JP2015560846A JP2015560846A JP2016510737A5 JP 2016510737 A5 JP2016510737 A5 JP 2016510737A5 JP 2015560846 A JP2015560846 A JP 2015560846A JP 2015560846 A JP2015560846 A JP 2015560846A JP 2016510737 A5 JP2016510737 A5 JP 2016510737A5
Authority
JP
Japan
Prior art keywords
plant cell
domain
cell according
plant
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015560846A
Other languages
English (en)
Japanese (ja)
Other versions
JP6622591B2 (ja
JP2016510737A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IL2014/050231 external-priority patent/WO2014136117A1/en
Publication of JP2016510737A publication Critical patent/JP2016510737A/ja
Publication of JP2016510737A5 publication Critical patent/JP2016510737A5/ja
Application granted granted Critical
Publication of JP6622591B2 publication Critical patent/JP6622591B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015560846A 2013-03-06 2014-03-06 TNFαポリペプチド阻害薬を発現する植物細胞の、治療法における使用 Expired - Fee Related JP6622591B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361773392P 2013-03-06 2013-03-06
US61/773,392 2013-03-06
PCT/IL2014/050231 WO2014136117A1 (en) 2013-03-06 2014-03-06 USE OF PLANT CELLS EXPRESSING A TNFalpha POLYPEPTIDE INHIBITOR IN THERAPY

Publications (3)

Publication Number Publication Date
JP2016510737A JP2016510737A (ja) 2016-04-11
JP2016510737A5 true JP2016510737A5 (enExample) 2017-04-06
JP6622591B2 JP6622591B2 (ja) 2019-12-18

Family

ID=50473737

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015560846A Expired - Fee Related JP6622591B2 (ja) 2013-03-06 2014-03-06 TNFαポリペプチド阻害薬を発現する植物細胞の、治療法における使用

Country Status (8)

Country Link
US (1) US10087232B2 (enExample)
EP (1) EP2964669B1 (enExample)
JP (1) JP6622591B2 (enExample)
CN (1) CN105121460A (enExample)
AU (1) AU2014224174B2 (enExample)
BR (1) BR112015021707A2 (enExample)
CA (1) CA2902727C (enExample)
WO (1) WO2014136117A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2904035A1 (en) 2013-03-06 2014-09-12 Protalix Ltd. Tnf alpha inhibitor polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same
US10000551B2 (en) 2014-09-11 2018-06-19 Protalix Ltd. Chimeric polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same
US10465003B2 (en) * 2016-02-05 2019-11-05 Janssen Biotech, Inc. Anti-TNF antibodies, compositions, methods and use for the treatment or prevention of type 1 diabetes
WO2017192580A1 (en) * 2016-05-02 2017-11-09 The Regents Of The University Of California Novel fusion proteins for treating inflammatory diseases
SG11201809620UA (en) * 2016-05-02 2018-11-29 Hoffmann La Roche The contorsbody - a single chain target binder
US11213570B2 (en) * 2016-06-10 2022-01-04 The Johns Hopkins University Use of C1q/TNF-related protein-1 (CTRP1) to treat fatty liver disease
EP3717068A1 (en) * 2017-11-27 2020-10-07 Baliopharm AG ANTI-huTNFR1 THERAPY OF NONALCOHOLIC STEATOHEPATITIS
WO2020163529A1 (en) * 2019-02-06 2020-08-13 Oncoimmune, Inc. Targeting cd24-siglec interactions for the treatment and prevention of nonalcoholic steatohepatitis
WO2024054452A1 (en) * 2022-09-06 2024-03-14 Biovie Inc. Methods for the treatment of mild cognitive impairment

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3901654A (en) 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3853987A (en) 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
US3867517A (en) 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
NL171930C (nl) 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US3850578A (en) 1973-03-12 1974-11-26 H Mcconnell Process for assaying for biologically active molecules
US3935074A (en) 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4034074A (en) 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
US3984533A (en) 1975-11-13 1976-10-05 General Electric Company Electrophoretic method of detecting antigen-antibody reaction
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4879219A (en) 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
CA1192510A (en) 1981-05-27 1985-08-27 Lawrence E. Pelcher Rna plant virus vector or portion thereof, a method of construction thereof, and a method of producing a gene derived product therefrom
JPS6054684A (ja) 1983-09-05 1985-03-29 Teijin Ltd 新規dνa及びハイブリツドdνa
US5011771A (en) 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
CA1288073C (en) 1985-03-07 1991-08-27 Paul G. Ahlquist Rna transformation vector
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
GB8608850D0 (en) 1986-04-11 1986-05-14 Diatech Ltd Packaging system
JPS6314693A (ja) 1986-07-04 1988-01-21 Sumitomo Chem Co Ltd 植物ウイルスrnaベクタ−
ATE108828T1 (de) 1987-02-09 1994-08-15 Lubrizol Genetics Inc Hybrides rns-virus.
US5316931A (en) 1988-02-26 1994-05-31 Biosource Genetics Corp. Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes
US5693507A (en) 1988-09-26 1997-12-02 Auburn University Genetic engineering of plant chloroplasts
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5302523A (en) 1989-06-21 1994-04-12 Zeneca Limited Transformation of plant cells
US5192659A (en) 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
UA48104C2 (uk) 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
US5281521A (en) 1992-07-20 1994-01-25 The Trustees Of The University Of Pennsylvania Modified avidin-biotin technique
IL113484A0 (en) 1994-04-28 1995-07-31 Immunex Corp Viral proteins pharmaceutical compositions containing them their preparation and use
US6096871A (en) 1995-04-14 2000-08-01 Genentech, Inc. Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life
ATE279947T1 (de) 1996-03-18 2004-11-15 Univ Texas Immunglobulinähnliche domäne mit erhöhten halbwertszeiten
US20050032211A1 (en) 1996-09-26 2005-02-10 Metabogal Ltd. Cell/tissue culturing device, system and method
US7361331B2 (en) * 1996-10-18 2008-04-22 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Plant bioreactors
WO1999004001A1 (en) 1997-07-21 1999-01-28 Zymogenetics, Inc. Tumor necrosis factor receptor ztnfr-5
US6040498A (en) 1998-08-11 2000-03-21 North Caroline State University Genetically engineered duckweed
EP1090133B8 (en) 1998-06-22 2009-11-25 HER MAJESTY THE QUEEN IN RIGHT OF CANADA, as represented by the Minister of Agriculture and Agri-Food Production of il-10 in non-food crop plant bioreactor
US20040220103A1 (en) 1999-04-19 2004-11-04 Immunex Corporation Soluble tumor necrosis factor receptor treatment of medical disorders
US6391683B1 (en) 2000-06-21 2002-05-21 Siliconware Precision Industries Co., Ltd. Flip-chip semiconductor package structure and process for fabricating the same
US8022270B2 (en) 2000-07-31 2011-09-20 Biolex Therapeutics, Inc. Expression of biologically active polypeptides in duckweed
NZ523912A (en) 2000-07-31 2005-03-24 Biolex Inc Expression of biologically active polypeptides in duckweed
UA81743C2 (uk) * 2000-08-07 2008-02-11 Центокор, Инк. МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
CN1533438A (zh) 2001-06-08 2004-09-29 �����Ŵ��Ƽ���˾ 在植物生产蛋白质的方法
SI1478394T1 (sl) 2002-02-27 2008-12-31 Immunex Corp STABILIZIRAN TNFR-Fc SESTAVEK Z ARGININOM
CA2498776A1 (en) 2002-09-13 2004-03-25 The University Of Queensland Gene expression system based on codon translation efficiency
US7855063B2 (en) 2003-04-16 2010-12-21 Yeda Research And Development Co. Ltd. Partially deglycosylated glucocerebrosidase polypeptide and crystals thereof
JP2007520196A (ja) * 2003-07-03 2007-07-26 ユニクロップ・リミテッド 新規なrubiscoプロモーターおよびその使用
CA2568633C (en) 2004-10-15 2008-04-01 Oren Halpern A system and a method for improving the captured images of digital still cameras
JP2009501784A (ja) 2005-07-18 2009-01-22 プロタリクス リミテッド 生物学的に活性な高分子の粘膜投与または経腸投与
EP2150608B1 (en) 2007-05-07 2017-11-29 Protalix Ltd. Large scale disposable bioreactor
RS60129B1 (sr) * 2011-01-20 2020-05-29 Protalix Ltd Kompozicije alfa-galaktozidaze
WO2012125720A2 (en) * 2011-03-14 2012-09-20 University Of Louisville Research Foundation, Inc. Polypeptides having immunoactivating activity and methods of producing the same
EP2718328A4 (en) * 2011-06-08 2014-12-24 Acceleron Pharma Inc COMPOSITIONS AND METHODS FOR INCREASING THE HALF TIME OF SERUM
EP2791171A1 (en) 2011-12-16 2014-10-22 Synthon Biopharmaceuticals B.V. EXPRESSION OF SECRETORY IgA ANTIBODIES IN DUCKWEED
CA2904035A1 (en) 2013-03-06 2014-09-12 Protalix Ltd. Tnf alpha inhibitor polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same
US11562502B2 (en) 2015-11-09 2023-01-24 Cognex Corporation System and method for calibrating a plurality of 3D sensors with respect to a motion conveyance

Similar Documents

Publication Publication Date Title
JP6514259B2 (ja) 抗炎症活性を有するペプチド、及びそれを含む組成物
Kolumam et al. Sustained brown fat stimulation and insulin sensitization by a humanized bispecific antibody agonist for fibroblast growth factor receptor 1/βKlotho complex
Rinaldi et al. HCC and molecular targeting therapies: back to the future
TWI640320B (zh) 抗發炎胜肽及包含其之成分(三)
JP5916946B2 (ja) モノクローナルIgA抗体の製造方法
Kretz et al. Should we keep walking along the trail for pancreatic cancer treatment? Revisiting TNF-related apoptosis-inducing ligand for anticancer therapy
JP2019536793A5 (enExample)
JP2022020666A (ja) 改善されたtnf結合因子
CN106999545B (zh) 用于在有需要的受试者中诱导饱食和延长饱感的药物和食物组合物
JP2019535292A5 (enExample)
CN112839952A (zh) 包含基于pd-1的嵌合蛋白的组合疗法
Sun et al. Intestinal fungi and antifungal secretory immunoglobulin A in Crohn’s disease
US20160106799A1 (en) Carbohydrate Compounds for Nutritional and Therapeutic Use
Qian et al. Hypotensive activity of transgenic rice seed accumulating multiple antihypertensive peptides
Cao et al. Periplasmic expression optimization of VEGFR2 D3 adopting response surface methodology: antiangiogenic activity study
JPWO2007122885A1 (ja) インターロイキン産生調節剤、該インターロイキン産生調節剤を含む医薬組成物及び飲食品、並びにその製造方法
CN113512117A (zh) 一种可结合cd206的抗体及其应用
Dadfarma et al. Identification of the effects of acid-resistant Lactobacillus casei metallopeptidase gene under colon-specific promoter on the colorectal and breast cancer cell lines
CN112912384A (zh) 组合疗法
AU2022229900A1 (en) Combination therapies with sirp alpha-based chimeric proteins
CN105916975B (zh) 重组专性厌氧革兰氏阳性菌
JP2014500245A5 (enExample)
KR20160086864A (ko) 항염증 활성을 갖는 펩티드 및 이를 포함하는 조성물
CA2720210A1 (en) Compositions comprising antibodies or antibody fragments
Risse et al. Products of the fos and jun proto-oncogenes bind cooperatively to the AP1 DNA recognition sequence