JP2016509471A - バイオマーカーの検出および収集のための方法およびデバイス - Google Patents

バイオマーカーの検出および収集のための方法およびデバイス Download PDF

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JP2016509471A
JP2016509471A JP2015548022A JP2015548022A JP2016509471A JP 2016509471 A JP2016509471 A JP 2016509471A JP 2015548022 A JP2015548022 A JP 2015548022A JP 2015548022 A JP2015548022 A JP 2015548022A JP 2016509471 A JP2016509471 A JP 2016509471A
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probes
probe
biomarker
microneedle
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JP2016509471A5 (https=
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タヒル エー． マフムード，
タヒル エー． マフムード，
トビン ジェイ． ディッカーソン，
トビン ジェイ． ディッカーソン，
ナディル エー． マフムード，
ナディル エー． マフムード，
ペテル チャペック，
ペテル チャペック，
Original Assignee
マインデラ コーポレイション
マインデラ コーポレイション
ザ スクリプス リサーチ インスティテュート
ザ スクリプス リサーチ インスティテュート
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Publication of JP2016509471A publication Critical patent/JP2016509471A/ja
Publication of JP2016509471A5 publication Critical patent/JP2016509471A5/ja
Priority to JP2019162715A priority Critical patent/JP7572774B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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    • G01N33/54366—Apparatus specially adapted for solid-phase testing
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    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
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    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
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    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6813—Hybridisation assays
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/08—Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
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    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B2010/008—Interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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    • A61B2562/04—Arrangements of multiple sensors of the same type
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    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/685—Microneedles
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JP2015548022A 2012-12-14 2013-12-13 バイオマーカーの検出および収集のための方法およびデバイス Withdrawn JP2016509471A (ja)

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US201261737237P 2012-12-14 2012-12-14
US61/737,237 2012-12-14
PCT/US2013/075187 WO2014093934A1 (en) 2012-12-14 2013-12-13 Methods and devices for detection and acquisition of biomarkers

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JP2015548022A Withdrawn JP2016509471A (ja) 2012-12-14 2013-12-13 バイオマーカーの検出および収集のための方法およびデバイス
JP2019162715A Active JP7572774B2 (ja) 2012-12-14 2019-09-06 バイオマーカーの検出および収集のための方法およびデバイス
JP2022157858A Withdrawn JP2022177287A (ja) 2012-12-14 2022-09-30 バイオマーカーの検出および収集のための方法およびデバイス
JP2024039825A Active JP7704916B2 (ja) 2012-12-14 2024-03-14 バイオマーカーの検出および収集のための方法およびデバイス
JP2025108143A Pending JP2025138775A (ja) 2012-12-14 2025-06-26 バイオマーカーの検出および収集のための方法およびデバイス

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JP2022157858A Withdrawn JP2022177287A (ja) 2012-12-14 2022-09-30 バイオマーカーの検出および収集のための方法およびデバイス
JP2024039825A Active JP7704916B2 (ja) 2012-12-14 2024-03-14 バイオマーカーの検出および収集のための方法およびデバイス
JP2025108143A Pending JP2025138775A (ja) 2012-12-14 2025-06-26 バイオマーカーの検出および収集のための方法およびデバイス

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US (3) US9540684B2 (https=)
EP (2) EP2931356B1 (https=)
JP (5) JP2016509471A (https=)
KR (4) KR20240091108A (https=)
CN (3) CN114176586B (https=)
AU (5) AU2013358890A1 (https=)
CA (1) CA2892587A1 (https=)
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JP6231252B1 (ja) * 2016-07-08 2017-11-15 花王株式会社 核酸試料の調製方法
JP2018000206A (ja) * 2016-07-08 2018-01-11 花王株式会社 核酸試料の調製方法
JP2020504749A (ja) * 2016-12-28 2020-02-13 ネクスモス カンパニー リミテッドＮｅｘｍｏｓ Ｃｏ．，Ｌｔｄ． アプタマーでコーティングされたマイクロニードルベースの診断用皮膚パッチの製造方法及びそのパッチ
JP2022520165A (ja) * 2019-01-30 2022-03-29 ラファス カンパニー リミテッド マイクロニードルパッチを利用した最小浸湿的皮膚生体検査方法
JP2022554046A (ja) * 2020-08-10 2022-12-28 カティス バイオメディカル リサーチ センター マイクロニードルパッチを含む最小侵襲的皮膚状態の診断キット

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CN114176586B (zh) 2012-12-14 2025-01-07 明德拉公司 用于检测和获取生物标志物的方法和装置
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
WO2019161126A1 (en) 2018-02-14 2019-08-22 Dermtech, Inc. Novel gene classifiers and uses thereof in non-melanoma skin cancers
EP3825411A1 (en) 2014-06-18 2021-05-26 Clear Gene, Inc. Methods, compositions, and devices for rapid analysis of biological markers
US10321858B2 (en) * 2014-08-18 2019-06-18 Proteadx, Inc. Apparatus and methods for transdermal sensing of analytes in interstitial fluid and associated data transmission systems
EP3215170A4 (en) 2014-11-05 2018-04-25 Veracyte, Inc. Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data
WO2017007271A1 (ko) * 2015-07-09 2017-01-12 주식회사 넥스모스 앱타머 코팅된 마이크로니들 기반 진단용 피부 패치
GB201517373D0 (en) * 2015-10-01 2015-11-18 Ge Healthcare Uk Ltd Micro-Needle Sampling Device And Use Thereof
WO2017106790A1 (en) 2015-12-18 2017-06-22 Clear Gene, Inc. Methods, compositions, kits and devices for rapid analysis of biological markers
WO2017147706A1 (en) * 2016-03-02 2017-09-08 Jp Scientific Limited Method and instrument for extracting a component from a sample
JP2020522690A (ja) * 2017-06-02 2020-07-30 ベラサイト インコーポレイテッド 肺疾病の特定又はモニタリング方法及びシステム
US12275994B2 (en) 2017-06-22 2025-04-15 Clear Gene, Inc. Methods and compositions for the analysis of cancer biomarkers
WO2019089567A1 (en) 2017-10-30 2019-05-09 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
DE102018103215B3 (de) * 2018-02-13 2019-08-14 Gna Biosolutions Gmbh Verfahren und Vorrichtung zur Extraktion einer Nukleinsäure aus einer Probenflüssigkeit
CN109459569A (zh) * 2018-07-28 2019-03-12 南昌大学 一种免血样肿瘤早期监测的方法
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