JP2016508969A5 - - Google Patents
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- JP2016508969A5 JP2016508969A5 JP2015548050A JP2015548050A JP2016508969A5 JP 2016508969 A5 JP2016508969 A5 JP 2016508969A5 JP 2015548050 A JP2015548050 A JP 2015548050A JP 2015548050 A JP2015548050 A JP 2015548050A JP 2016508969 A5 JP2016508969 A5 JP 2016508969A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- cancer
- alkyl
- patent document
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- LBNUURWIDGNVSU-UHFFFAOYSA-N CCCN(C(CN1C)=O)C1=O Chemical compound CCCN(C(CN1C)=O)C1=O LBNUURWIDGNVSU-UHFFFAOYSA-N 0.000 description 1
- WFLQKGQIUPCFDB-UHFFFAOYSA-N CCCN(C(CO1)=O)C1=O Chemical compound CCCN(C(CO1)=O)C1=O WFLQKGQIUPCFDB-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261737658P | 2012-12-14 | 2012-12-14 | |
| US61/737,658 | 2012-12-14 | ||
| PCT/US2013/075505 WO2014093988A2 (en) | 2012-12-14 | 2013-12-16 | Methods and compositions for inhibiting cnksr1 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016508969A JP2016508969A (ja) | 2016-03-24 |
| JP2016508969A5 true JP2016508969A5 (enExample) | 2017-02-23 |
| JP6357292B2 JP6357292B2 (ja) | 2018-07-11 |
Family
ID=50935099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015548050A Active JP6357292B2 (ja) | 2012-12-14 | 2013-12-16 | Ｃｎｋｓｒ１を阻害するための方法及び組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9340532B2 (enExample) |
| EP (1) | EP2931280B1 (enExample) |
| JP (1) | JP6357292B2 (enExample) |
| AU (1) | AU2013358876B2 (enExample) |
| CA (1) | CA2895162C (enExample) |
| MX (2) | MX393754B (enExample) |
| WO (1) | WO2014093988A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2895162C (en) | 2012-12-14 | 2021-03-09 | D. Lynn Kirkpatrick | Methods and compositions for inhibiting cnksr1 |
| US10227356B2 (en) | 2015-04-20 | 2019-03-12 | Phusis Therapeutics, Inc. | Compounds, compositions and methods for inhibiting CNKSR1 |
| WO2018125983A1 (en) | 2016-12-30 | 2018-07-05 | Mitobridge, Inc. | Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (acmsd) inhibitors |
| CN110698411B (zh) * | 2018-07-09 | 2023-05-09 | 四川大学 | 一类4-(胺烷基)酞嗪-1-酮类化合物、其制备方法和用途 |
| US20230312482A1 (en) * | 2020-07-28 | 2023-10-05 | Mirati Therapeutics, Inc. | Sos1 inhibitors |
| WO2022187804A1 (en) * | 2021-03-02 | 2022-09-09 | Icahn School Of Medicine At Mount Sinai | Benzoxazolone inhibitors of inflammasomes |
| WO2024192873A1 (zh) * | 2023-03-20 | 2024-09-26 | 杭州天玑济世生物科技有限公司 | 一类具有萘胺结构的小分子化合物的用途 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA775563A (en) | 1968-01-09 | Frank W. Horner Limited | Hypoglycemic thiadiazoles | |
| GB828963A (en) | 1956-08-03 | 1960-02-24 | Rhone Poulenc Sa | Pharmaceutical compositions containing 2-p-aminobenzenesulphonamido-5-t-butyl-1, 3, 4-thiadiazole |
| US3821222A (en) | 1971-11-22 | 1974-06-28 | Chevron Res | Hydrocarbyl sulfenylmercapto pyrimidines |
| US4017489A (en) | 1975-07-10 | 1977-04-12 | The Goodyear Tire & Rubber Company | Process of preparing unsymmetrical disulfides |
| DE2556011A1 (de) | 1975-12-12 | 1977-06-23 | Merck Patent Gmbh | Disulfide |
| IE47592B1 (en) * | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
| GB2152497B (en) | 1983-11-28 | 1987-08-05 | Otsuka Kagaku Kk | Process for the preparation of azetidinone derivatives |
| FR2573077B1 (fr) | 1984-11-13 | 1987-02-13 | Sanofi Sa | Nouveaux derives thiosulfonates, leur procede de preparation ainsi que les compositions pharmaceutiques les contenant |
| US4939140A (en) * | 1985-11-07 | 1990-07-03 | Pfizer Inc. | Heterocyclic oxophthalazinyl acetic acids |
| US4990523A (en) | 1989-06-19 | 1991-02-05 | A. H. Robins Company, Incorporated | Treatment of chronic inflammatory joint disease with arylsulfonamides |
| GB9507415D0 (en) * | 1994-06-08 | 1995-05-31 | Zylepsis Ltd | Production and uses of caffeic acid and derivatives thereof |
| US6139875A (en) | 1998-09-29 | 2000-10-31 | Eastman Chemical Company | Aqueous enteric coating composition and low gastric permeability enteric coating |
| FR2815032B1 (fr) | 2000-10-10 | 2003-08-08 | Pf Medicament | Nouveaux derives d'aminophenyle piperazine ou d'amino phenyle piperide inhibiteurs de proteines prenyl transferase ainsi que leurs preparations |
| WO2002083064A2 (en) | 2001-04-10 | 2002-10-24 | Merck & Co., Inc. | A method of treating cancer |
| NZ531245A (en) * | 2001-08-15 | 2005-09-30 | Icos Corp | 2H-phthalazin-1-ones and methods for use thereof |
| GB0205693D0 (en) | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
| US20060142178A1 (en) | 2002-04-08 | 2006-06-29 | Barnett Stanley F | Method of treating cancer |
| GB0215823D0 (en) * | 2002-07-09 | 2002-08-14 | Astrazeneca Ab | Quinazoline derivatives |
| US20040102360A1 (en) | 2002-10-30 | 2004-05-27 | Barnett Stanley F. | Combination therapy |
| JP4787155B2 (ja) | 2003-06-24 | 2011-10-05 | イシス イノベーション リミテッド | タンパク質のジスルフィド結合形成およびグリコシル化の方法とそれに用いられる試薬 |
| BRPI0412380A (pt) | 2003-07-08 | 2006-09-19 | Novartis Ag | compostos de benzenossulfonilamino e composições farmacêuticas que contêm esses compostos |
| CA2559579A1 (en) | 2004-03-19 | 2005-09-29 | The Tapemark Company | Thermoplastic films and methods for making |
| JP2007530589A (ja) | 2004-03-26 | 2007-11-01 | アンフォラ ディスカバリー コーポレーション | 特定のトリアゾールを基礎とする化合物、組成物、およびそれらの使用 |
| SE0402635D0 (sv) | 2004-10-29 | 2004-10-29 | Astrazeneca Ab | Chemical compounds |
| DE102005011822A1 (de) * | 2005-03-15 | 2006-09-21 | Merck Patent Gmbh | Phthalazinone |
| ATE487706T1 (de) | 2005-10-06 | 2010-11-15 | Sanofi Aventis | Cyclische n-ä1,3,4ü-thiadiazol-2-yl- benzsulfonamide, verfahren zu deren herstellung und deren verwendung als arzneimittel |
| WO2007106391A1 (en) | 2006-03-10 | 2007-09-20 | Lymphosign Inc. | Compounds for modulating cell proliferation, compositions and methods related thereto |
| KR20090017498A (ko) | 2006-04-04 | 2009-02-18 | 더 리젠트스 오브 더 유니이버시티 오브 캘리포니아 | Ｐｉ３ 키나제 길항물질 |
| CA2674078C (en) | 2006-12-26 | 2012-03-20 | Femmepharma Holding Company, Inc. | Topical administration of danazol |
| CA2721371C (en) | 2008-04-14 | 2016-07-12 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Small molecule inhibitors of the pleckstrin homology domain and methods for using same |
| WO2010085968A1 (en) * | 2008-12-30 | 2010-08-05 | European Molecular Biology Laboratory (Embl) | Toluidine sulfonamides and their use as hif-inhibitors |
| CN102448951B (zh) * | 2009-04-06 | 2017-05-10 | 安吉奥斯医药品有限公司 | 丙酮酸激酶m2调节剂、治疗组合物和相关使用方法 |
| CA2773561A1 (en) | 2009-09-14 | 2011-03-17 | Phusis Therapeutics Inc. | Pharmaceutical compositions and formulations including inhibitors of the pleckstrin homology domain and methods for using same |
| KR20140027974A (ko) * | 2011-04-05 | 2014-03-07 | 버텍스 파마슈티칼스 인코포레이티드 | Ｔｒａ 키나제의 억제제로서 유용한 아미노피라진 화합물 |
| CA2895162C (en) | 2012-12-14 | 2021-03-09 | D. Lynn Kirkpatrick | Methods and compositions for inhibiting cnksr1 |
-
2013
- 2013-12-16 CA CA2895162A patent/CA2895162C/en active Active
- 2013-12-16 MX MX2019015648A patent/MX393754B/es unknown
- 2013-12-16 EP EP13863280.7A patent/EP2931280B1/en active Active
- 2013-12-16 JP JP2015548050A patent/JP6357292B2/ja active Active
- 2013-12-16 AU AU2013358876A patent/AU2013358876B2/en active Active
- 2013-12-16 MX MX2015007608A patent/MX372739B/es active IP Right Grant
- 2013-12-16 US US14/649,349 patent/US9340532B2/en active Active
- 2013-12-16 WO PCT/US2013/075505 patent/WO2014093988A2/en not_active Ceased
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