JP2016506239A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016506239A5 JP2016506239A5 JP2015545470A JP2015545470A JP2016506239A5 JP 2016506239 A5 JP2016506239 A5 JP 2016506239A5 JP 2015545470 A JP2015545470 A JP 2015545470A JP 2015545470 A JP2015545470 A JP 2015545470A JP 2016506239 A5 JP2016506239 A5 JP 2016506239A5
- Authority
- JP
- Japan
- Prior art keywords
- dna
- interest
- cell
- gene
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261732156P | 2012-11-30 | 2012-11-30 | |
| US61/732,156 | 2012-11-30 | ||
| PCT/US2013/072412 WO2014085711A1 (en) | 2012-11-30 | 2013-11-27 | A novel cell line screening method |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018167792A Division JP6785272B2 (ja) | 2012-11-30 | 2018-09-07 | 新規な細胞株スクリーニング方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016506239A JP2016506239A (ja) | 2016-03-03 |
| JP2016506239A5 true JP2016506239A5 (https=) | 2016-12-28 |
| JP6442411B2 JP6442411B2 (ja) | 2018-12-26 |
Family
ID=49880972
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015545470A Expired - Fee Related JP6442411B2 (ja) | 2012-11-30 | 2013-11-27 | 新規な細胞株スクリーニング方法 |
| JP2018167792A Expired - Fee Related JP6785272B2 (ja) | 2012-11-30 | 2018-09-07 | 新規な細胞株スクリーニング方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018167792A Expired - Fee Related JP6785272B2 (ja) | 2012-11-30 | 2018-09-07 | 新規な細胞株スクリーニング方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9910038B2 (https=) |
| EP (2) | EP2925867B1 (https=) |
| JP (2) | JP6442411B2 (https=) |
| CN (2) | CN110257412B (https=) |
| WO (1) | WO2014085711A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014085711A1 (en) * | 2012-11-30 | 2014-06-05 | Larix Biosciences Llc | A novel cell line screening method |
| WO2016132122A1 (en) * | 2015-02-17 | 2016-08-25 | University Of Edinburgh | Assay construct |
| CN119876218A (zh) * | 2018-07-09 | 2025-04-25 | 杰诺维有限公司 | 用于在重组酶介导的核酸序列向工程化的接受细胞发生盒交换整合期间追踪和操纵细胞的细胞表面标签交换(cste)系统 |
| CN112673109A (zh) * | 2018-09-07 | 2021-04-16 | 免疫医疗有限责任公司 | 细胞选择方法 |
| WO2020264253A1 (en) * | 2019-06-26 | 2020-12-30 | Genentech, Inc. | Randomized configuration targeted integration of nucleic acids |
| WO2025176217A1 (en) * | 2024-02-22 | 2025-08-28 | The University Of Hong Kong | Conditional splicing system for tight control of viral overlapping genes |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040038392A1 (en) * | 2000-06-08 | 2004-02-26 | Tatsurou Shibui | Expression vector enabling screening of cells with high expression of recombinant protein, transformant with high expression of recombinant protein and utilization thereof |
| US6406863B1 (en) * | 2000-06-23 | 2002-06-18 | Genetastix Corporation | High throughput generation and screening of fully human antibody repertoire in yeast |
| US20030059763A1 (en) * | 2001-01-26 | 2003-03-27 | Andrew Saxon | Immunoglobulin class switch recombination |
| GB0118337D0 (en) | 2001-07-27 | 2001-09-19 | Lonza Biologics Plc | Method for selecting antibody expressing cells |
| WO2003070931A2 (de) * | 2002-02-21 | 2003-08-28 | Vision 7 Gmbh | Verfahren zur ortsspezifischen dna-rekombination |
| WO2004007686A2 (en) * | 2002-07-12 | 2004-01-22 | Emory University | Methods and transgenic mouse model for identifying and modulating factors involved in the production of reactive oxygen intermediates |
| AU2003283995A1 (en) * | 2002-09-30 | 2004-04-19 | Protein Design Labs, Inc. | Efficient generation of stable expression cell lines through the use of scorable homeostatic reporter genes |
| WO2005073375A1 (en) * | 2004-01-30 | 2005-08-11 | Maxygen Holdings Ltd. | Regulated stop codon readthrough |
| KR20080073293A (ko) | 2005-10-14 | 2008-08-08 | 메디뮨 엘엘씨 | 항체 라이브러리의 세포 디스플레이 |
| WO2008070367A2 (en) | 2006-11-01 | 2008-06-12 | Facet Biotech Corporation | Mammalian cell-based immunoglobulin display libraries |
| WO2008151219A1 (en) | 2007-06-04 | 2008-12-11 | Regeneron Pharmaceuticals, Inc. | Enhanced expression and stability regions |
| US7947495B2 (en) | 2007-11-01 | 2011-05-24 | Abbott Biotherapeutics Corp. | Immunoglobulin display vectors |
| DK2329020T3 (da) | 2008-08-28 | 2013-06-10 | Novartis Ag | Celleoverfladepræsentation af polypeptidisoformer ved hjælp af stopcodon-overspringelse |
| CN101671653B (zh) * | 2009-09-22 | 2012-05-23 | 浙江大学 | 一种hiv侵染细胞的筛选系统及其应用 |
| WO2011061937A1 (en) * | 2009-11-19 | 2011-05-26 | Immuno Tec Laboratory Co., Ltd. | Methods for producing antibody-producing cells that produce desired polypeptides |
| JP2011182645A (ja) * | 2010-03-04 | 2011-09-22 | Kyushu Univ | 動物細胞ディスプレイ法およびそれを利用した完全ヒトモノクローナル抗体の体外成熟法 |
| WO2014085711A1 (en) * | 2012-11-30 | 2014-06-05 | Larix Biosciences Llc | A novel cell line screening method |
-
2013
- 2013-11-27 WO PCT/US2013/072412 patent/WO2014085711A1/en not_active Ceased
- 2013-11-27 EP EP13812267.6A patent/EP2925867B1/en active Active
- 2013-11-27 CN CN201910335307.XA patent/CN110257412B/zh not_active Expired - Fee Related
- 2013-11-27 JP JP2015545470A patent/JP6442411B2/ja not_active Expired - Fee Related
- 2013-11-27 EP EP18000323.8A patent/EP3382026B1/en active Active
- 2013-11-27 CN CN201380062665.9A patent/CN104870646B/zh active Active
- 2013-11-27 US US14/092,786 patent/US9910038B2/en not_active Expired - Fee Related
-
2018
- 2018-02-19 US US15/899,051 patent/US10816548B2/en active Active
- 2018-09-07 JP JP2018167792A patent/JP6785272B2/ja not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016506239A5 (https=) | ||
| ES2712632T3 (es) | Preparación de bibliotecas de variantes de proteínas expresadas en células eucariotas y su uso para seleccionar moléculas de unión | |
| Suzuki et al. | VCre/VloxP and SCre/SloxP: new site-specific recombination systems for genome engineering | |
| JP2012511920A5 (https=) | ||
| AU2023251528A1 (en) | Enhanced Production Of Immunoglobulins | |
| US20170137491A1 (en) | Novel Method | |
| US12060391B2 (en) | Constructs for continuous monitoring of live cells | |
| JP2020043860A (ja) | ハイスループットなレセプター:リガンド同定の方法 | |
| JP6159256B2 (ja) | 膜結合レポーター分子および細胞ソーティングにおけるそれらの使用 | |
| JP6709156B2 (ja) | 新規真核細胞および目的の生成物を組換え発現させるための方法 | |
| Lee et al. | Development of the “Three-step MACS”: a novel strategy for isolating rare cell populations in the absence of known cell surface markers from complex animal tissue | |
| US20200072820A1 (en) | Method of Selecting for Antibodies | |
| CN105378071A (zh) | 用于产生稳定转染细胞的方法和组合物 | |
| EP2925867B1 (en) | A novel cell line screening method | |
| Li et al. | Development of a membrane-anchored ligand and receptor yeast two-hybrid system for ligand-receptor interaction identification | |
| Evtushenko et al. | hTERT-driven immortalization of RDEB fibroblast and keratinocyte cell lines followed by Cre-mediated transgene elimination | |
| Yang et al. | Uncovering receptor-ligand interactions using a high-avidity CRISPR activation screening platform | |
| Aebischer-Gumy et al. | SPLICELECT™: an adaptable cell surface display technology based on alternative splicing allowing the qualitative and quantitative prediction of secreted product at a single-cell level | |
| Niemann et al. | Generation and characterization of an inducible Cx43 overexpression system in mouse embryonic stem cells | |
| CN116323922A (zh) | 筛选靶向CD47-SIRPα免疫检查点的候选药物的方法和试剂盒 | |
| Wilke et al. | Streamlining homogeneous glycoprotein production for biophysical and structural applications by targeted cell line development | |
| JP2017525368A5 (https=) | ||
| HRP20210301T1 (hr) | Djelotvorna selektivnost rekombinantnih proteina | |
| Suresh et al. | Tools for retargeting proteins within Aspergillus nidulans | |
| Dolt et al. | A universal vector for high-efficiency multi-fragment recombineering of BACs and knock-in constructs |