JP2016504315A - 三価デングウイルス製剤に関する組成物、投与方法および使用 - Google Patents

三価デングウイルス製剤に関する組成物、投与方法および使用 Download PDF

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Publication number
JP2016504315A
JP2016504315A JP2015547441A JP2015547441A JP2016504315A JP 2016504315 A JP2016504315 A JP 2016504315A JP 2015547441 A JP2015547441 A JP 2015547441A JP 2015547441 A JP2015547441 A JP 2015547441A JP 2016504315 A JP2016504315 A JP 2016504315A
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Prior art keywords
dengue
virus
vaccine
dengue virus
den
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JP2015547441A
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Japanese (ja)
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JP2016504315A5 (enExample
Inventor
ティ． スティンチコム、ダン
ティ． スティンチコム、ダン
エヌ． ブレウー、ジョセフ
エヌ． ブレウー、ジョセフ
オソリオ、ジョージ
ディ． パーチドス、カラランボス
ディ． パーチドス、カラランボス
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Takeda Vaccines Inc
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Takeda Vaccines Inc
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Publication of JP2016504315A publication Critical patent/JP2016504315A/ja
Publication of JP2016504315A5 publication Critical patent/JP2016504315A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2015547441A 2012-12-14 2013-12-07 三価デングウイルス製剤に関する組成物、投与方法および使用 Pending JP2016504315A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261737679P 2012-12-14 2012-12-14
US61/737,679 2012-12-14
PCT/US2013/073757 WO2014093182A1 (en) 2012-12-14 2013-12-07 Compositions, methods of administration and uses for trivalent dengue virus formulations

Publications (2)

Publication Number Publication Date
JP2016504315A true JP2016504315A (ja) 2016-02-12
JP2016504315A5 JP2016504315A5 (enExample) 2017-01-26

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JP2015547441A Pending JP2016504315A (ja) 2012-12-14 2013-12-07 三価デングウイルス製剤に関する組成物、投与方法および使用

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Country Link
US (2) US9878031B2 (enExample)
EP (1) EP2931310A4 (enExample)
JP (1) JP2016504315A (enExample)
CA (1) CA2933472A1 (enExample)
WO (1) WO2014093182A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113637086B (zh) * 2013-03-15 2024-10-11 武田疫苗股份有限公司 用于疫苗中的登革热病毒嵌合式构建物的组合物及方法
WO2016130786A2 (en) * 2015-02-15 2016-08-18 Integral Molecular, Inc. Flaviviridae proteins and virions and methods of use thereof
SG10201913383RA (en) 2016-04-13 2020-03-30 Takeda Vaccines Inc Compositions and methods of vaccination against dengue virus in children and young adults
ES2908304T3 (es) * 2018-09-05 2022-04-28 Takeda Vaccines Inc Dosis unitaria de vacuna contra el dengue y administración de la misma
US11464815B2 (en) 2018-09-05 2022-10-11 Takeda Vaccines, Inc. Dengue vaccine unit dose and administration thereof
US11426461B2 (en) 2018-09-05 2022-08-30 Takeda Vaccines, Inc. Methods for preventing dengue and hepatitis A
EP4013451A1 (en) * 2019-08-16 2022-06-22 Takeda Vaccines, Inc. Methods for preventing dengue and hepatitis a
WO2024108087A1 (en) * 2022-11-18 2024-05-23 Takeda Vaccines, Inc. A method for determining the proportion of a live, attenuated flavivirus having a nucleotide sequence comprising at least one attenuation locus in a formulation

Citations (1)

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JP2010505801A (ja) * 2006-10-04 2010-02-25 サノフィ・パスツール ４種のデング血清型に対する免疫付与の方法

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CA2941182A1 (en) 2000-02-16 2001-08-23 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Avirulent, immunogenic flavivirus chimeras
US20040120964A1 (en) 2001-10-29 2004-06-24 Mikszta John A. Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
US20040259224A1 (en) 2002-05-31 2004-12-23 Farshad Guirakhoo Tetravalent Dengue vaccines
US8029802B2 (en) 2004-10-20 2011-10-04 Sanofi Pasteur Biologics Co. Vaccines against Japanese encephalitis virus and West Nile virus
ATE475706T1 (de) 2005-06-17 2010-08-15 Sanofi Pasteur Abgeschwächter dengue-serotyp-2-stamm
BRPI0613328A2 (pt) * 2005-06-17 2011-01-04 Sanofi Pasteur cepa do vìrus da dengue-1 vivo atenuado, composição imunogênica, composição de vacina, ácido nucléico isolado, poliproteìna isolada e fragmento de poliproteìna
JP5227172B2 (ja) 2005-08-10 2013-07-03 サノフィ パスツール バイオロジクス リミテッド ライアビリティ カンパニー デングウイルス感染に対するワクチン接種
BR122020023372B1 (pt) 2006-08-15 2021-11-30 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Vírus da dengue do tipo 3 (den3) atenuado e composição imunogênica
US20100316670A1 (en) 2007-06-14 2010-12-16 Blaney Joseph E Chimeric sle/dengue type 4 antigenic viruses
WO2010085358A2 (en) 2009-01-23 2010-07-29 The Board Of Regents Of The University Of Texas System Flaviviruses expressing the prm, e, and ns1 proteins of other flaviviruses and uses thereof
US8968996B2 (en) * 2009-06-01 2015-03-03 Takeda Vaccines, Inc. Compositions and methods for rapid immunization against dengue virus
NZ597000A (en) * 2009-06-01 2014-07-25 Takeda Vaccines Inc Compositions and methods for administration of vaccines against dengue virus
WO2013188315A1 (en) * 2012-06-10 2013-12-19 Inviragen, Inc. Compositions and methods for administration of vaccines against dengue virus
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ＡＭＥＲＩＣＡＮ ＪＯＵＲＮＡＬ ＯＦ ＴＲＯＰＩＣＡＬ ＭＥＤＩＣＩＮＥ ＡＮＤ ＨＹＧＩＥＮＥ, vol. 22, no. 3, JPN5009017937, 1973, pages 375 - 381, ISSN: 0004004105 *
ＡＭＥＲＩＣＡＮ ＪＯＵＲＮＡＬ ＯＦ ＴＲＯＰＩＣＡＬ ＭＥＤＩＣＩＮＥ ＡＮＤ ＨＹＧＩＥＮＥ, vol. 22, no. 3, JPN6012047727, 1973, pages 365 - 374, ISSN: 0004004108 *
ＡＭＥＲＩＣＡＮ ＪＯＵＲＮＡＬ ＯＦ ＴＲＯＰＩＣＡＬ ＭＥＤＩＣＩＮＥ ＡＮＤ ＨＹＧＩＥＮＥ, vol. 80, no. 2, JPN6017033314, 2009, pages 302 - 311, ISSN: 0004004109 *
N. BHAMARAPRAVATI. ET AL.: "The clinical trial of trivalent dengue vaccine.", ＳＯＵＴＨＥＡＳＴ ＡＳＩＡＮ ＪＯＵＲＮＡＬ ＯＦ ＴＲＯＰＩＣＡＬ ＭＥＤＩＣＩＮＥ ＡＮＤ Ｐ, vol. 21, no. 4, JPN6017033309, 1990, pages 709, ISSN: 0004004106 *
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臨床と微生物, vol. 29, no. 2, JPN6012047713, 2002, pages 25 - 29, ISSN: 0004004110 *

Also Published As

Publication number Publication date
US20180228887A1 (en) 2018-08-16
US9878031B2 (en) 2018-01-30
EP2931310A1 (en) 2015-10-21
EP2931310A4 (en) 2016-05-25
US20150335727A1 (en) 2015-11-26
WO2014093182A1 (en) 2014-06-19
CA2933472A1 (en) 2014-06-19

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