JP2016504315A - 三価デングウイルス製剤に関する組成物、投与方法および使用 - Google Patents

三価デングウイルス製剤に関する組成物、投与方法および使用 Download PDF

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Publication number
JP2016504315A
JP2016504315A JP2015547441A JP2015547441A JP2016504315A JP 2016504315 A JP2016504315 A JP 2016504315A JP 2015547441 A JP2015547441 A JP 2015547441A JP 2015547441 A JP2015547441 A JP 2015547441A JP 2016504315 A JP2016504315 A JP 2016504315A
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Prior art keywords
dengue
virus
vaccine
dengue virus
den
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JP2015547441A
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Japanese (ja)
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JP2016504315A5 (enExample
Inventor
ティ． スティンチコム、ダン
ティ． スティンチコム、ダン
エヌ． ブレウー、ジョセフ
エヌ． ブレウー、ジョセフ
オソリオ、ジョージ
ディ． パーチドス、カラランボス
ディ． パーチドス、カラランボス
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Takeda Vaccines Inc
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Takeda Vaccines Inc
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Publication of JP2016504315A publication Critical patent/JP2016504315A/ja
Publication of JP2016504315A5 publication Critical patent/JP2016504315A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2015547441A 2012-12-14 2013-12-07 三価デングウイルス製剤に関する組成物、投与方法および使用 Pending JP2016504315A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261737679P 2012-12-14 2012-12-14
US61/737,679 2012-12-14
PCT/US2013/073757 WO2014093182A1 (en) 2012-12-14 2013-12-07 Compositions, methods of administration and uses for trivalent dengue virus formulations

Publications (2)

Publication Number Publication Date
JP2016504315A true JP2016504315A (ja) 2016-02-12
JP2016504315A5 JP2016504315A5 (enExample) 2017-01-26

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JP2015547441A Pending JP2016504315A (ja) 2012-12-14 2013-12-07 三価デングウイルス製剤に関する組成物、投与方法および使用

Country Status (5)

Country Link
US (2) US9878031B2 (enExample)
EP (1) EP2931310A4 (enExample)
JP (1) JP2016504315A (enExample)
CA (1) CA2933472A1 (enExample)
WO (1) WO2014093182A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102389908B1 (ko) * 2013-03-15 2022-04-26 다케다 백신즈 인코포레이티드 백신 내의 뎅기 바이러스 키메라 구조체를 위한 조성물 및 방법
WO2016130786A2 (en) * 2015-02-15 2016-08-18 Integral Molecular, Inc. Flaviviridae proteins and virions and methods of use thereof
KR102611235B1 (ko) * 2016-04-13 2023-12-08 다케다 백신즈 인코포레이티드 어린이 및 젊은 성인에서 뎅기 바이러스에 대한 백신접종 조성물 및 방법
US11464815B2 (en) 2018-09-05 2022-10-11 Takeda Vaccines, Inc. Dengue vaccine unit dose and administration thereof
US11426461B2 (en) 2018-09-05 2022-08-30 Takeda Vaccines, Inc. Methods for preventing dengue and hepatitis A
ES2908304T3 (es) * 2018-09-05 2022-04-28 Takeda Vaccines Inc Dosis unitaria de vacuna contra el dengue y administración de la misma
PH12022550261A1 (en) * 2019-08-16 2023-06-26 Takeda Vaccines Inc Methods for preventing dengue and hepatitis a
EP4375381A1 (en) * 2022-11-18 2024-05-29 Takeda Vaccines, Inc. A method for determining the proportion of a live, attenuated flavivirus having a nucleotide sequence comprising at least one attenuation locus in a formulation

Citations (1)

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JP2010505801A (ja) * 2006-10-04 2010-02-25 サノフィ・パスツール ４種のデング血清型に対する免疫付与の方法

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WO2001060847A2 (en) 2000-02-16 2001-08-23 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Avirulent, immunogenic flavivirus chimeras
US20040120964A1 (en) 2001-10-29 2004-06-24 Mikszta John A. Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
AU2003239932A1 (en) 2002-05-31 2003-12-19 Acambis, Inc. Tetravalent dengue vaccines
NZ584079A (en) 2004-10-20 2011-10-28 Acambis Inc Vaccines against japanese encephalitis virus and west nile virus
CA2611934C (en) * 2005-06-17 2015-11-03 Sanofi Pasteur Dengue serotype 1 attenuated strain
MX2007015872A (es) 2005-06-17 2008-04-21 Sanofi Pasteur Cepa atenuada del serotipo 2 del dengue.
EP1924280A4 (en) 2005-08-10 2008-12-10 Acambis Inc VACCINATION AGAINST DENGUE VIRUS INFECTION
EP2589602B1 (en) 2006-08-15 2016-04-06 The Government of the U.S.A., as repr. by the Secretary, Dept. of Health & Human Services, the Nat. Inst. of Health Development of dengue virus vaccine components
WO2008157136A1 (en) 2007-06-14 2008-12-24 The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services Chimeric sle/dengue type 4 antigenic viruses
WO2010085358A2 (en) 2009-01-23 2010-07-29 The Board Of Regents Of The University Of Texas System Flaviviruses expressing the prm, e, and ns1 proteins of other flaviviruses and uses thereof
US8968996B2 (en) * 2009-06-01 2015-03-03 Takeda Vaccines, Inc. Compositions and methods for rapid immunization against dengue virus
WO2013188315A1 (en) 2012-06-10 2013-12-19 Inviragen, Inc. Compositions and methods for administration of vaccines against dengue virus
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ＡＭＥＲＩＣＡＮ ＪＯＵＲＮＡＬ ＯＦ ＴＲＯＰＩＣＡＬ ＭＥＤＩＣＩＮＥ ＡＮＤ ＨＹＧＩＥＮＥ, vol. 22, no. 3, JPN5009017937, 1973, pages 375 - 381, ISSN: 0004004105 *
ＡＭＥＲＩＣＡＮ ＪＯＵＲＮＡＬ ＯＦ ＴＲＯＰＩＣＡＬ ＭＥＤＩＣＩＮＥ ＡＮＤ ＨＹＧＩＥＮＥ, vol. 22, no. 3, JPN6012047727, 1973, pages 365 - 374, ISSN: 0004004108 *
ＡＭＥＲＩＣＡＮ ＪＯＵＲＮＡＬ ＯＦ ＴＲＯＰＩＣＡＬ ＭＥＤＩＣＩＮＥ ＡＮＤ ＨＹＧＩＥＮＥ, vol. 80, no. 2, JPN6017033314, 2009, pages 302 - 311, ISSN: 0004004109 *
N. BHAMARAPRAVATI. ET AL.: "The clinical trial of trivalent dengue vaccine.", ＳＯＵＴＨＥＡＳＴ ＡＳＩＡＮ ＪＯＵＲＮＡＬ ＯＦ ＴＲＯＰＩＣＡＬ ＭＥＤＩＣＩＮＥ ＡＮＤ Ｐ, vol. 21, no. 4, JPN6017033309, 1990, pages 709, ISSN: 0004004106 *
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Also Published As

Publication number Publication date
EP2931310A1 (en) 2015-10-21
WO2014093182A1 (en) 2014-06-19
CA2933472A1 (en) 2014-06-19
EP2931310A4 (en) 2016-05-25
US20150335727A1 (en) 2015-11-26
US20180228887A1 (en) 2018-08-16
US9878031B2 (en) 2018-01-30

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