ATE475706T1 - Abgeschwächter dengue-serotyp-2-stamm - Google Patents
Abgeschwächter dengue-serotyp-2-stammInfo
- Publication number
- ATE475706T1 ATE475706T1 AT06755943T AT06755943T ATE475706T1 AT E475706 T1 ATE475706 T1 AT E475706T1 AT 06755943 T AT06755943 T AT 06755943T AT 06755943 T AT06755943 T AT 06755943T AT E475706 T1 ATE475706 T1 AT E475706T1
- Authority
- AT
- Austria
- Prior art keywords
- strain
- dengue serotype
- attenuated dengue
- attenuated
- serotype
- Prior art date
Links
- 208000001490 Dengue Diseases 0.000 title 1
- 206010012310 Dengue fever Diseases 0.000 title 1
- 230000002238 attenuated effect Effects 0.000 title 1
- 208000025729 dengue disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- C12N7/08—Inactivation or attenuation by serial passage of virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24161—Methods of inactivation or attenuation
- C12N2770/24164—Methods of inactivation or attenuation by serial passage
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69127405P | 2005-06-17 | 2005-06-17 | |
| PCT/IB2006/001513 WO2006134443A1 (en) | 2005-06-17 | 2006-06-07 | Dengue serotype 2 attenuated strain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE475706T1 true ATE475706T1 (de) | 2010-08-15 |
Family
ID=37103341
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06755943T ATE475706T1 (de) | 2005-06-17 | 2006-06-07 | Abgeschwächter dengue-serotyp-2-stamm |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US7641908B2 (de) |
| EP (1) | EP1891210B1 (de) |
| JP (1) | JP5075120B2 (de) |
| KR (2) | KR20080018271A (de) |
| CN (1) | CN101238209B (de) |
| AR (1) | AR053914A1 (de) |
| AT (1) | ATE475706T1 (de) |
| AU (1) | AU2006257621B2 (de) |
| BR (1) | BRPI0613287A2 (de) |
| CA (1) | CA2611954C (de) |
| DE (1) | DE602006015807D1 (de) |
| IL (1) | IL188068A0 (de) |
| MX (1) | MX2007015872A (de) |
| MY (2) | MY144542A (de) |
| NO (1) | NO20076360L (de) |
| TW (1) | TWI375722B (de) |
| WO (1) | WO2006134443A1 (de) |
| ZA (1) | ZA200710752B (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0613287A2 (pt) * | 2005-06-17 | 2010-12-28 | Sanofi Pasteur | cepa do vìrus da dengue-2 vivo atenuada, composição imunogênica, composição de vacina, ácido nucléico isolado, poliproteìna isolada codificadas pela seq id n .1 ou fragmentos desta e fragmento da poliproteìna |
| CU23586A1 (es) * | 2005-11-22 | 2010-10-30 | Ct Ingenieria Genetica Biotech | Métodos y proteínas para el tratamiento profiláctico y/o terapéutico de los cuatro serotipos del virus de dengue y otros flavivirus |
| FR2903605A1 (fr) * | 2006-07-12 | 2008-01-18 | Sanofi Pasteur Sa | Methode d'immunisation contre les quatres serotypes de la dengue |
| FR2909286B1 (fr) * | 2006-12-01 | 2012-06-08 | Sanofi Pasteur | Methode d'immunisation contre les 4 serotypes de la dengue |
| CN101139638B (zh) * | 2007-05-08 | 2010-05-26 | 深圳太太基因工程有限公司 | 一种用于检测登革病毒ⅲ型核苷酸片段的引物和探针序列 |
| MX2010008799A (es) | 2008-03-05 | 2010-09-07 | Sanofi Pasteur | Proceso para estabilizar una composicion de vacuna que contiene adyuvante. |
| EP2143440A1 (de) | 2008-07-09 | 2010-01-13 | Sanofi Pasteur | Stabilisierungssubstanz und Impfzusammensetzung, die ein oder mehrere abgeschwächte lebende Flaviviridae enthält |
| US8968996B2 (en) | 2009-06-01 | 2015-03-03 | Takeda Vaccines, Inc. | Compositions and methods for rapid immunization against dengue virus |
| WO2010141386A1 (en) * | 2009-06-01 | 2010-12-09 | Inviragen, Inc. | Compositions and methods for administration of vaccines against dengue virus |
| JP6057460B2 (ja) | 2009-08-31 | 2017-01-11 | ジェン−プローブ・インコーポレーテッド | デングウイルスアッセイ |
| CN102755642B (zh) * | 2012-07-13 | 2014-01-08 | 中国食品药品检定研究院 | 一种炭疽疫苗的制备方法 |
| CN104812408A (zh) * | 2012-07-24 | 2015-07-29 | 赛诺菲巴斯德有限公司 | 用于防止登革热病毒感染的疫苗组合物 |
| EP3932422A1 (de) | 2012-07-24 | 2022-01-05 | Sanofi Pasteur | Impfstoffzusammensetzungen zur vorbeugung von dengue-virus-infektionen |
| BR112015012515B1 (pt) | 2012-11-30 | 2023-04-11 | Sanofi Pasteur | Uso de antígenos, construções de ácido nucleico ou vetores virais capazes de expressar uma partícula do tipo vírus (vlp) da dengue e de uma vacina contra sarampo, uma vacina contra caxumba e uma vacina contra rubéola |
| WO2014093182A1 (en) | 2012-12-14 | 2014-06-19 | Inviragen, Inc. | Compositions, methods of administration and uses for trivalent dengue virus formulations |
| CN113637694A (zh) | 2013-03-15 | 2021-11-12 | 武田疫苗股份有限公司 | 用于疫苗中的登革热病毒嵌合式构建物的组合物及方法 |
| WO2014204892A1 (en) | 2013-06-21 | 2014-12-24 | Merck Sharp & Dohme Corp. | Dengue virus vaccine compositions and methods of use thereof |
| CN103382509A (zh) * | 2013-07-17 | 2013-11-06 | 浙江国际旅行卫生保健中心 | 逆转录-环介导等温扩增检测登革2型病毒的试剂及检测方法 |
| EP3188751A1 (de) | 2014-09-02 | 2017-07-12 | Sanofi Pasteur | Impfstoffzusammensetzungen gegen dengue-viruserkrankungen |
| CR20170280A (es) | 2014-12-22 | 2017-08-21 | Merck Sharp & Dohme | Composiciones de vacuna para el virus del dengue y métodos de uso de las mismas |
| EP3316905A1 (de) | 2015-07-03 | 2018-05-09 | Sanofi Pasteur | Gleichzeitige impfung gegen dengue und gelbfieber |
| CN108699534B (zh) * | 2015-11-27 | 2022-05-24 | Km生物医药股份公司 | 具有登革热病毒减毒株库的活病毒和包含其作为抗原的登革热疫苗 |
| WO2019069130A1 (en) | 2017-10-05 | 2019-04-11 | Sanofi Pasteur | COMPOSITIONS FOR RECALL VACCINATION AGAINST DENGUE |
| ES2908304T3 (es) | 2018-09-05 | 2022-04-28 | Takeda Vaccines Inc | Dosis unitaria de vacuna contra el dengue y administración de la misma |
| US11464815B2 (en) | 2018-09-05 | 2022-10-11 | Takeda Vaccines, Inc. | Dengue vaccine unit dose and administration thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6093296A (en) * | 1995-06-07 | 1996-12-30 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Infectious dengue 2 virus pdk-53 as quadravalent vaccine |
| AU779280B2 (en) * | 1999-03-26 | 2005-01-13 | Walter Reed Army Institute Of Research | Multivalent dengue virus vaccine |
| PT1159968E (pt) * | 2000-05-30 | 2008-11-20 | Univ Mahidol | Estirpes atenuadas de vírus do dengue e a sua utilização numa composição de vacina |
| WO2002024876A2 (en) * | 2000-09-25 | 2002-03-28 | Polymun Scientific Immunbiologische Forschung Gmbh | Live influenza vaccine and method of manufacture |
| CA3060687C (en) * | 2001-05-22 | 2021-05-04 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses |
| WO2003092592A2 (en) * | 2002-05-03 | 2003-11-13 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Dengue tetravalent vaccine containing a common 30 nucleotide deletion in the 3'-utr of dengue types 1,2,3, and 4, or antigenic chimeric dengue viruses 1,2,3, and 4 |
| BRPI0613287A2 (pt) * | 2005-06-17 | 2010-12-28 | Sanofi Pasteur | cepa do vìrus da dengue-2 vivo atenuada, composição imunogênica, composição de vacina, ácido nucléico isolado, poliproteìna isolada codificadas pela seq id n .1 ou fragmentos desta e fragmento da poliproteìna |
-
2006
- 2006-06-07 BR BRPI0613287-1A patent/BRPI0613287A2/pt not_active IP Right Cessation
- 2006-06-07 CA CA2611954A patent/CA2611954C/en not_active Expired - Fee Related
- 2006-06-07 AU AU2006257621A patent/AU2006257621B2/en not_active Ceased
- 2006-06-07 DE DE602006015807T patent/DE602006015807D1/de active Active
- 2006-06-07 MX MX2007015872A patent/MX2007015872A/es active IP Right Grant
- 2006-06-07 KR KR1020087001413A patent/KR20080018271A/ko active IP Right Grant
- 2006-06-07 EP EP06755943A patent/EP1891210B1/de active Active
- 2006-06-07 AT AT06755943T patent/ATE475706T1/de not_active IP Right Cessation
- 2006-06-07 JP JP2008516431A patent/JP5075120B2/ja not_active Expired - Fee Related
- 2006-06-07 KR KR1020147001614A patent/KR101582163B1/ko not_active IP Right Cessation
- 2006-06-07 WO PCT/IB2006/001513 patent/WO2006134443A1/en active Application Filing
- 2006-06-07 CN CN2006800285156A patent/CN101238209B/zh not_active Expired - Fee Related
- 2006-06-14 MY MYPI20062801A patent/MY144542A/en unknown
- 2006-06-14 MY MYPI2011006054A patent/MY161457A/en unknown
- 2006-06-15 US US11/453,344 patent/US7641908B2/en active Active
- 2006-06-16 AR ARP060102567A patent/AR053914A1/es unknown
- 2006-06-16 TW TW095121611A patent/TWI375722B/zh not_active IP Right Cessation
-
2007
- 2007-12-11 ZA ZA200710752A patent/ZA200710752B/xx unknown
- 2007-12-12 IL IL188068A patent/IL188068A0/en not_active IP Right Cessation
- 2007-12-12 NO NO20076360A patent/NO20076360L/no not_active Application Discontinuation
-
2009
- 2009-12-08 US US12/633,459 patent/US8067566B2/en active Active
-
2011
- 2011-10-25 US US13/281,255 patent/US8795688B2/en active Active
-
2014
- 2014-08-04 US US14/450,529 patent/US20150031857A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE602006015807D1 (de) | 2010-09-09 |
| JP2008546383A (ja) | 2008-12-25 |
| AU2006257621A1 (en) | 2006-12-21 |
| TW200738881A (en) | 2007-10-16 |
| KR20140019034A (ko) | 2014-02-13 |
| TWI375722B (en) | 2012-11-01 |
| JP5075120B2 (ja) | 2012-11-14 |
| EP1891210B1 (de) | 2010-07-28 |
| WO2006134443A1 (en) | 2006-12-21 |
| MY161457A (en) | 2017-04-14 |
| NO20076360L (no) | 2008-03-11 |
| CA2611954C (en) | 2014-01-28 |
| US20100174057A1 (en) | 2010-07-08 |
| KR101582163B1 (ko) | 2016-01-05 |
| US8795688B2 (en) | 2014-08-05 |
| CN101238209B (zh) | 2013-02-13 |
| IL188068A0 (en) | 2008-03-20 |
| CA2611954A1 (en) | 2006-12-21 |
| US8067566B2 (en) | 2011-11-29 |
| US20070026016A1 (en) | 2007-02-01 |
| MX2007015872A (es) | 2008-04-21 |
| BRPI0613287A2 (pt) | 2010-12-28 |
| EP1891210A1 (de) | 2008-02-27 |
| AU2006257621B2 (en) | 2011-08-11 |
| US7641908B2 (en) | 2010-01-05 |
| US20120083585A1 (en) | 2012-04-05 |
| US20150031857A1 (en) | 2015-01-29 |
| KR20080018271A (ko) | 2008-02-27 |
| AR053914A1 (es) | 2007-05-23 |
| CN101238209A (zh) | 2008-08-06 |
| MY144542A (en) | 2011-09-30 |
| ZA200710752B (en) | 2008-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |