ATE537171T1 - Aryl-isoxazol-4-yl-imidazoä1,5-aüpyridin-deriva e - Google Patents
Aryl-isoxazol-4-yl-imidazoä1,5-aüpyridin-deriva eInfo
- Publication number
- ATE537171T1 ATE537171T1 AT06841391T AT06841391T ATE537171T1 AT E537171 T1 ATE537171 T1 AT E537171T1 AT 06841391 T AT06841391 T AT 06841391T AT 06841391 T AT06841391 T AT 06841391T AT E537171 T1 ATE537171 T1 AT E537171T1
- Authority
- AT
- Austria
- Prior art keywords
- imidazoä1
- aüpyridine
- deriva
- isoxazole
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05112988 | 2005-12-27 | ||
PCT/EP2006/069792 WO2007074089A1 (en) | 2005-12-27 | 2006-12-18 | Aryl-isoxazol-4-yl-imidazo[1, 5-a]pyridine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE537171T1 true ATE537171T1 (de) | 2011-12-15 |
Family
ID=37909303
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06841391T ATE537171T1 (de) | 2005-12-27 | 2006-12-18 | Aryl-isoxazol-4-yl-imidazoä1,5-aüpyridin-deriva e |
Country Status (17)
Country | Link |
---|---|
US (1) | US7399769B2 (de) |
EP (1) | EP1968977B1 (de) |
JP (1) | JP4864982B2 (de) |
KR (1) | KR101033719B1 (de) |
CN (1) | CN101346377B (de) |
AR (1) | AR058728A1 (de) |
AT (1) | ATE537171T1 (de) |
AU (1) | AU2006331363B2 (de) |
BR (1) | BRPI0620760A2 (de) |
CA (1) | CA2633536A1 (de) |
ES (1) | ES2376357T3 (de) |
IL (1) | IL192236A0 (de) |
NO (1) | NO20082748L (de) |
RU (1) | RU2420527C2 (de) |
TW (1) | TWI324156B (de) |
WO (1) | WO2007074089A1 (de) |
ZA (1) | ZA200805354B (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL1968973T3 (pl) * | 2005-12-27 | 2012-03-30 | Hoffmann La Roche | Pochodne aryloizoksazol-4-iloimidazolu |
BRPI0814718A2 (pt) | 2007-06-22 | 2015-02-24 | Hoffmann La Roche | Derivados de isoxazol-imidazol |
BRPI0820112B8 (pt) | 2007-12-04 | 2021-05-25 | Hoffmann La Roche | derivados de isoxazol-piridina, seu uso e processos de preparação e medicamento |
US20150374705A1 (en) | 2012-02-14 | 2015-12-31 | Shanghai Institues for Biological Sciences | Substances for treatment or relief of pain |
WO2014001279A1 (en) | 2012-06-26 | 2014-01-03 | Aniona Aps | A phenyl triazole derivative and its use for modulating the gabaa receptor complex |
US9475797B2 (en) | 2012-06-26 | 2016-10-25 | Saniona A/S | Phenyl triazole derivative and its use for modulating the GABAA receptor complex |
CN104411699B (zh) | 2012-06-26 | 2017-06-13 | 萨尼奥纳有限责任公司 | 苯基三唑衍生物及其用于调节gabaa 受体复合体的用途 |
WO2014001278A1 (en) | 2012-06-26 | 2014-01-03 | Aniona Aps | A phenyl triazole derivative and its use for modulating the gabaa receptor complex |
WO2014001280A1 (en) | 2012-06-26 | 2014-01-03 | Aniona Aps | A phenyl triazole derivative and its use for modulating the gabaa receptor complex |
TWI664164B (zh) | 2014-02-13 | 2019-07-01 | 美商英塞特控股公司 | 作為lsd1抑制劑之環丙胺 |
WO2015123437A1 (en) | 2014-02-13 | 2015-08-20 | Incyte Corporation | Cyclopropylamines as lsd1 inhibitors |
SG10201806849WA (en) | 2014-02-13 | 2018-09-27 | Incyte Corp | Cyclopropylamines as lsd1 inhibitors |
US9695180B2 (en) | 2014-07-10 | 2017-07-04 | Incyte Corporation | Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors |
WO2016007722A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Triazolopyridines and triazolopyrazines as lsd1 inhibitors |
TWI687419B (zh) | 2014-07-10 | 2020-03-11 | 美商英塞特公司 | 作為lsd1抑制劑之咪唑并吡啶及咪唑并吡嗪 |
JP6995623B2 (ja) | 2015-04-03 | 2022-01-14 | インサイト・コーポレイション | Lsd1阻害剤としてのヘテロ環式化合物 |
TWI765860B (zh) | 2015-08-12 | 2022-06-01 | 美商英塞特公司 | Lsd1抑制劑之鹽 |
BR102019014802A2 (pt) | 2018-07-20 | 2020-02-04 | Boehringer Ingelheim Int | difluorometil-fenil triazóis |
US10968200B2 (en) | 2018-08-31 | 2021-04-06 | Incyte Corporation | Salts of an LSD1 inhibitor and processes for preparing the same |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE236158T1 (de) * | 1999-11-12 | 2003-04-15 | Neurogen Corp | Bicyclische und tricyclische heteroaromatische verbindungen |
EP1448561B1 (de) * | 2001-11-20 | 2008-02-20 | Eli Lilly And Company | Beta-3 adrenergische agonisten |
-
2006
- 2006-12-18 AT AT06841391T patent/ATE537171T1/de active
- 2006-12-18 BR BRPI0620760-0A patent/BRPI0620760A2/pt not_active IP Right Cessation
- 2006-12-18 CN CN2006800491806A patent/CN101346377B/zh not_active Expired - Fee Related
- 2006-12-18 EP EP06841391A patent/EP1968977B1/de not_active Not-in-force
- 2006-12-18 AU AU2006331363A patent/AU2006331363B2/en not_active Ceased
- 2006-12-18 WO PCT/EP2006/069792 patent/WO2007074089A1/en active Application Filing
- 2006-12-18 JP JP2008547940A patent/JP4864982B2/ja not_active Expired - Fee Related
- 2006-12-18 RU RU2008125040/04A patent/RU2420527C2/ru not_active IP Right Cessation
- 2006-12-18 CA CA002633536A patent/CA2633536A1/en not_active Abandoned
- 2006-12-18 ES ES06841391T patent/ES2376357T3/es active Active
- 2006-12-18 US US11/640,768 patent/US7399769B2/en not_active Expired - Fee Related
- 2006-12-18 KR KR1020087015509A patent/KR101033719B1/ko not_active IP Right Cessation
- 2006-12-25 TW TW095148805A patent/TWI324156B/zh not_active IP Right Cessation
- 2006-12-26 AR ARP060105770A patent/AR058728A1/es not_active Application Discontinuation
-
2008
- 2008-06-13 NO NO20082748A patent/NO20082748L/no not_active Application Discontinuation
- 2008-06-16 IL IL192236A patent/IL192236A0/en unknown
- 2008-06-19 ZA ZA200805354A patent/ZA200805354B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
JP2009521517A (ja) | 2009-06-04 |
US20070191421A1 (en) | 2007-08-16 |
BRPI0620760A2 (pt) | 2011-11-22 |
ZA200805354B (en) | 2009-10-28 |
CA2633536A1 (en) | 2007-07-05 |
KR101033719B1 (ko) | 2011-05-09 |
CN101346377A (zh) | 2009-01-14 |
US7399769B2 (en) | 2008-07-15 |
IL192236A0 (en) | 2008-12-29 |
AU2006331363B2 (en) | 2012-07-05 |
WO2007074089A1 (en) | 2007-07-05 |
ES2376357T3 (es) | 2012-03-13 |
AR058728A1 (es) | 2008-02-20 |
EP1968977A1 (de) | 2008-09-17 |
RU2008125040A (ru) | 2010-02-10 |
JP4864982B2 (ja) | 2012-02-01 |
NO20082748L (no) | 2008-09-24 |
RU2420527C2 (ru) | 2011-06-10 |
KR20080072072A (ko) | 2008-08-05 |
TWI324156B (en) | 2010-05-01 |
EP1968977B1 (de) | 2011-12-14 |
AU2006331363A1 (en) | 2007-07-05 |
TW200734328A (en) | 2007-09-16 |
CN101346377B (zh) | 2011-05-11 |
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