JP2016503058A5 - - Google Patents
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- JP2016503058A5 JP2016503058A5 JP2015549612A JP2015549612A JP2016503058A5 JP 2016503058 A5 JP2016503058 A5 JP 2016503058A5 JP 2015549612 A JP2015549612 A JP 2015549612A JP 2015549612 A JP2015549612 A JP 2015549612A JP 2016503058 A5 JP2016503058 A5 JP 2016503058A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- formula
- compound
- thiosulfate
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261739609P | 2012-12-19 | 2012-12-19 | |
| US61/739,609 | 2012-12-19 | ||
| US201361758147P | 2013-01-29 | 2013-01-29 | |
| US61/758,147 | 2013-01-29 | ||
| PCT/US2013/076041 WO2014100135A1 (en) | 2012-12-19 | 2013-12-18 | Lfa-1 inhibitor formulations |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016503058A JP2016503058A (ja) | 2016-02-01 |
| JP2016503058A5 true JP2016503058A5 (cg-RX-API-DMAC7.html) | 2016-07-28 |
| JP6373867B2 JP6373867B2 (ja) | 2018-08-15 |
Family
ID=50979140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015549612A Active JP6373867B2 (ja) | 2012-12-19 | 2013-12-18 | Ｌｆａ−１阻害剤製剤 |
Country Status (20)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106995439B (zh) * | 2016-01-26 | 2019-09-20 | 镇江圣安医药有限公司 | 氘取代3-(甲磺酰基)-l-苯丙氨酸衍生物及其药物组合物、药物制剂和用途 |
| WO2019171260A1 (en) * | 2018-03-09 | 2019-09-12 | Mankind Pharma Ltd. | Pharmaceutical composition of lifitegrast |
| CN114025759A (zh) * | 2019-04-18 | 2022-02-08 | 阿祖拉眼科有限公司 | 用于治疗眼病的化合物和方法 |
| EP3842032A1 (en) | 2019-12-24 | 2021-06-30 | Warszawskie Zaklady Farmaceutyczne Polfa S.A. | A pharmaceutical formulation |
| CA3196146A1 (en) * | 2020-10-21 | 2022-04-28 | Azura Ophthalmics Ltd. | Compounds and methods for the treatment of ocular disorders |
| CN116211796A (zh) * | 2022-12-30 | 2023-06-06 | 新领先(重庆)医药科技有限公司 | 一种立他司特滴眼液及其制备方法 |
| KR20240109779A (ko) * | 2023-01-05 | 2024-07-12 | 주식회사 종근당 | 리피테그라스트와 토코페롤을 함유하는 건성안 예방 또는 치료용 약제학적 조성물 |
| KR20250033790A (ko) | 2023-09-01 | 2025-03-10 | 주식회사 와이에스생명과학 | 리피테그라스트 함유 점안 조성물 |
| WO2025093739A1 (en) | 2023-11-02 | 2025-05-08 | Novaliq Gmbh | Semifluorinated alkane compositions comprising lifitegrast |
| WO2025104294A1 (en) * | 2023-11-17 | 2025-05-22 | Bausch + Lomb Ireland Limited | Semifluorinated alkane small molecule lfa-1 antagonist combination compositions for treatment of ocular disorders |
| CN117771174B (zh) * | 2023-12-29 | 2025-07-29 | 鲁南贝特制药有限公司 | 一种立他司特滴眼液及其制备方法 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2694719A (en) | 1949-02-12 | 1954-11-16 | Opplt Jan | Method of stabilizing ascorbic acid with alkali-thiosulfate-carbamide-complexes |
| ES2098739T3 (es) * | 1992-05-13 | 1997-05-01 | Sandoz Ltd | Composiciones oftalmicas conteniendo una cyclosporin. |
| US5429819A (en) * | 1992-10-14 | 1995-07-04 | Matsushita Electric Industrial Co., Ltd. | Antiviral composition |
| IT1277707B1 (it) * | 1995-12-22 | 1997-11-11 | Chemedica Sa | Formulazione oftalmica a base di ialuronato di sodio per uso nella chirurgia oculare |
| JP4138910B2 (ja) * | 1997-07-02 | 2008-08-27 | 帝國製薬株式会社 | 経皮吸収性が良好で且つ皮膚刺激性の少ない塩酸アゼラスチン含有経皮製剤 |
| RU2149611C1 (ru) | 1998-04-06 | 2000-05-27 | Московская медицинская академия им. И.М. Сеченова | Капли для лечения воспалительных заболеваний глаз (варианты) |
| DE19954516A1 (de) * | 1999-11-12 | 2001-05-17 | Boehringer Ingelheim Int | Epinastin-haltige Lösungen |
| US6258814B1 (en) * | 2000-10-13 | 2001-07-10 | Schering Corporation | Method of using cetirizine and pharmaceutical compositions containing the same for inducing sleep |
| US8877168B1 (en) * | 2002-07-31 | 2014-11-04 | Senju Pharmaceuticals Co., Ltd. | Aqueous liquid preparations and light-stabilized aqueous liquid preparations |
| CA2532207A1 (en) * | 2003-07-11 | 2005-07-21 | Myriad Genetics, Inc. | Pharmaceutical methods, dosing regimes and dosage forms for the treatment of alzheimer's disease |
| FI119361B (fi) | 2003-09-26 | 2008-10-31 | Raute Oyj | Menetelmä viilun sorvaamiseksi |
| US20060073172A1 (en) * | 2004-10-01 | 2006-04-06 | Schneider L W | Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure |
| ES2530780T3 (es) * | 2005-05-17 | 2015-03-05 | Sarcode Bioscience Inc | Composiciones y métodos para el tratamiento de trastornos oculares |
| ES2437077T3 (es) * | 2005-07-08 | 2014-01-08 | Senju Pharmaceutical Co., Ltd. | Preparado oftálmico de absorción percutánea que comprende olopatadina |
| US7544893B2 (en) | 2007-07-25 | 2009-06-09 | Thomas & Betts International, Inc. | Extruded wire duct end cap |
| ITRM20080182A1 (it) * | 2008-04-07 | 2009-10-08 | Medivis S R L | Preparato oftalmico a base di dorzolamide e latanoprost per il trattamento topico del glaucoma. |
| EP2265125B1 (en) | 2008-04-15 | 2019-08-14 | SARcode Bioscience Inc. | Topical lfa-1 antagonists for use in localized treatment of immune related disorders |
| EP2265124A4 (en) * | 2008-04-15 | 2011-12-28 | Sarcode Bioscience Inc | AEROSOLISED LFA-1 ANTAGONISTS FOR THE USE IN THE LOCAL TREATMENT OF IMMUNE DISEASES |
| US8080562B2 (en) * | 2008-04-15 | 2011-12-20 | Sarcode Bioscience Inc. | Crystalline pharmaceutical and methods of preparation and use thereof |
| US20120028929A1 (en) * | 2008-09-19 | 2012-02-02 | Alacrity Bioscience, Inc. | Tetracycline stabilizing formulations |
| EP2346520B1 (en) * | 2008-11-17 | 2014-11-26 | Laila Pharmaceuticals Pvt. Ltd. | Curcuminoids and its metabolites for the application in ocular diseases |
| BRPI0924460A2 (pt) * | 2009-06-10 | 2018-03-27 | Obschestvo S Ogranichennoi Otvetstvennostyu '"Mitorekh" | composição farmacêutica para uso em oftalmologia médica e veterinária |
| KR20110001103A (ko) * | 2009-06-29 | 2011-01-06 | 에스케이케미칼주식회사 | 보관 안정성이 향상된 톨테로딘 함유 경피 투여 조성물 |
| CN102712584B (zh) * | 2009-11-23 | 2014-10-29 | 阿勒根公司 | 晶型ii的7-[3,5-二羟基-2-(3-羟基-5-苯基-戊-1-烯基)-环戊基]-n-乙基-庚-5-烯酰胺(比马前列素)、其制备方法和使用方法 |
| US20120190653A1 (en) * | 2011-01-20 | 2012-07-26 | Dow Pharmaceutical Sciences, Inc. | Therapeutic eye drop comprising doxycycline and a stabilizer |
| EP2675455A4 (en) * | 2011-02-18 | 2014-07-16 | M S Appasamy Associates | OPHTHALMIC COMPOSITION FOR DILATING PUPILS |
| RU2014102493A (ru) * | 2011-06-29 | 2015-08-10 | Аллерган, Инк. | Алкафтадин для применения при лечении уртикарии |
| EP2830627B1 (en) * | 2012-03-29 | 2024-05-01 | Epion Therapeutics, Inc. | Ocular treatment solutions, delivery devices and delivery augmentation methods |
| CN103230583A (zh) * | 2013-05-17 | 2013-08-07 | 江西省创欣药业集团有限公司 | 兽用治疗肠道疾病的烟酸诺氟沙星复方注射液及制备方法 |
-
2013
- 2013-12-18 NZ NZ708821A patent/NZ708821A/en unknown
- 2013-12-18 MX MX2019012375A patent/MX391620B/es unknown
- 2013-12-18 SI SI201331833T patent/SI2934510T1/sl unknown
- 2013-12-18 PT PT138657572T patent/PT2934510T/pt unknown
- 2013-12-18 ES ES13865757T patent/ES2846724T3/es active Active
- 2013-12-18 US US14/650,955 patent/US11058677B2/en active Active
- 2013-12-18 EP EP13865757.2A patent/EP2934510B1/en active Active
- 2013-12-18 CA CA2894170A patent/CA2894170C/en active Active
- 2013-12-18 PL PL13865757T patent/PL2934510T3/pl unknown
- 2013-12-18 KR KR1020157019352A patent/KR101891144B1/ko active Active
- 2013-12-18 EA EA201791321A patent/EA201791321A1/ru unknown
- 2013-12-18 HU HUE13865757A patent/HUE052299T2/hu unknown
- 2013-12-18 AU AU2013361579A patent/AU2013361579B2/en active Active
- 2013-12-18 JP JP2015549612A patent/JP6373867B2/ja active Active
- 2013-12-18 WO PCT/US2013/076041 patent/WO2014100135A1/en not_active Ceased
- 2013-12-18 BR BR112015014367-9A patent/BR112015014367B1/pt active IP Right Grant
- 2013-12-18 DK DK13865757.2T patent/DK2934510T3/da active
- 2013-12-18 EA EA201591180A patent/EA028008B1/ru unknown
- 2013-12-18 CN CN201380071760.5A patent/CN104955453B/zh active Active
- 2013-12-18 EP EP20204080.4A patent/EP3827823A1/en not_active Withdrawn
- 2013-12-18 MX MX2015007540A patent/MX368876B/es active IP Right Grant
-
2015
- 2015-06-18 IL IL239490A patent/IL239490B/en active IP Right Grant
- 2015-06-18 ZA ZA2015/04404A patent/ZA201504404B/en unknown
-
2016
- 2016-11-22 ZA ZA2016/08069A patent/ZA201608069B/en unknown
-
2021
- 2021-06-09 US US17/342,631 patent/US20220000859A1/en not_active Abandoned
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