JP2016502843A5 - - Google Patents
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- Publication number
- JP2016502843A5 JP2016502843A5 JP2015547559A JP2015547559A JP2016502843A5 JP 2016502843 A5 JP2016502843 A5 JP 2016502843A5 JP 2015547559 A JP2015547559 A JP 2015547559A JP 2015547559 A JP2015547559 A JP 2015547559A JP 2016502843 A5 JP2016502843 A5 JP 2016502843A5
- Authority
- JP
- Japan
- Prior art keywords
- bioactive agent
- capture
- cell
- solid surface
- target
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012867 bioactive agent Substances 0.000 claims description 17
- 102000004169 proteins and genes Human genes 0.000 claims description 17
- 108090000623 proteins and genes Proteins 0.000 claims description 17
- 239000003446 ligand Substances 0.000 claims description 15
- 239000007787 solid Substances 0.000 claims description 12
- 230000001413 cellular effect Effects 0.000 claims description 9
- 230000004927 fusion Effects 0.000 claims description 5
- 230000003993 interaction Effects 0.000 claims description 4
- 230000005291 magnetic effect Effects 0.000 claims description 3
- 239000011324 bead Substances 0.000 claims description 2
- 229920005989 resin Polymers 0.000 claims description 2
- 239000011347 resin Substances 0.000 claims description 2
- 150000003384 small molecules Chemical group 0.000 claims description 2
- 239000013592 cell lysate Substances 0.000 claims 3
- 230000003834 intracellular effect Effects 0.000 claims 1
- 230000002934 lysing effect Effects 0.000 claims 1
- 230000005298 paramagnetic effect Effects 0.000 claims 1
- 102000006830 Luminescent Proteins Human genes 0.000 description 1
- 108010047357 Luminescent Proteins Proteins 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000710 homodimer Substances 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261736426P | 2012-12-12 | 2012-12-12 | |
| US61/736,426 | 2012-12-12 | ||
| US201361788313P | 2013-03-15 | 2013-03-15 | |
| US61/788,313 | 2013-03-15 | ||
| PCT/US2013/074756 WO2014093671A1 (en) | 2012-12-12 | 2013-12-12 | Compositions and methods for capture of cellular targets of bioactive agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019025449A Division JP6999589B2 (ja) | 2012-12-12 | 2019-02-15 | 生物活性剤の細胞標的の捕捉のための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016502843A JP2016502843A (ja) | 2016-02-01 |
| JP2016502843A5 true JP2016502843A5 (show.php) | 2019-02-07 |
| JP6484178B2 JP6484178B2 (ja) | 2019-03-13 |
Family
ID=50934961
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015547559A Active JP6484178B2 (ja) | 2012-12-12 | 2013-12-12 | 生物活性剤の細胞標的の捕捉のための組成物および方法 |
| JP2019025449A Active JP6999589B2 (ja) | 2012-12-12 | 2019-02-15 | 生物活性剤の細胞標的の捕捉のための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019025449A Active JP6999589B2 (ja) | 2012-12-12 | 2019-02-15 | 生物活性剤の細胞標的の捕捉のための組成物および方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9551705B2 (show.php) |
| EP (1) | EP2931305B1 (show.php) |
| JP (2) | JP6484178B2 (show.php) |
| KR (2) | KR102227321B1 (show.php) |
| CN (1) | CN104853767B (show.php) |
| AU (2) | AU2013359160B2 (show.php) |
| BR (1) | BR112015013715A2 (show.php) |
| CA (1) | CA2894432C (show.php) |
| IL (1) | IL239213B (show.php) |
| SG (1) | SG11201504520XA (show.php) |
| WO (1) | WO2014093671A1 (show.php) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2012006616A (es) | 2009-12-09 | 2012-06-21 | Procter & Gamble | Productos para el cuidado de las telas y el hogar. |
| US9056885B2 (en) * | 2011-11-21 | 2015-06-16 | Promega Corporation | Carboxy X rhodamine analogs |
| KR102227321B1 (ko) | 2012-12-12 | 2021-03-12 | 프로메가 코포레이션 | 생체활성 제제의 세포 표적 포획을 위한 조성물 및 방법 |
| US10168323B2 (en) | 2013-03-15 | 2019-01-01 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
| US11072811B2 (en) | 2013-03-15 | 2021-07-27 | Promega Corporation | Substrates for covalent tethering of proteins to functional groups or solid surfaces |
| EP3304078B1 (en) * | 2015-06-05 | 2022-08-31 | Promega Corporation | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements |
| US10458988B2 (en) * | 2017-03-03 | 2019-10-29 | Musc Foundation For Research Development | Biotinylated luminescent probe |
| US12181452B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US11709156B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved analytical analysis |
| US11709155B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US12180581B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| EP3941195A4 (en) | 2019-03-20 | 2023-03-22 | Promega Corporation | PHOTOAFFINITY PROBES |
| US11918936B2 (en) | 2020-01-17 | 2024-03-05 | Waters Technologies Corporation | Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding |
| WO2022064447A1 (en) | 2020-09-24 | 2022-03-31 | Waters Technologies Corporation | Chromatographic hardware improvements for the separation of reactive molecules |
| JP2022182394A (ja) * | 2021-05-28 | 2022-12-08 | 独立行政法人国立病院機構 | 抗原固相化デバイス |
| WO2023287984A1 (en) * | 2021-07-14 | 2023-01-19 | University Of Maryland, Baltimore | Suberoylanilide hydroxamic acid (saha) drugs, conjugates, and nanoparticles, and methods of use thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5914095A (en) | 1989-04-07 | 1999-06-22 | Salutar, Inc. | Polychelants containg amide bonds |
| ES2136103T3 (es) | 1992-06-22 | 1999-11-16 | Kyowa Hakko Kogyo Kk | Procedimiento para la preparacion de derivados de estaurosporina. |
| US5756688A (en) | 1992-10-14 | 1998-05-26 | Sterling Winthrop Inc. | MR imaging compositions and methods |
| KR950703582A (ko) | 1992-10-14 | 1995-09-20 | 조이스 이. 마임스 | 킬레이트화 중합체(chelating polymers) |
| GB9503969D0 (en) | 1995-02-28 | 1995-04-19 | Sams Bernard | Incrementing mechanism |
| US20020004202A1 (en) | 2000-01-24 | 2002-01-10 | Cornish Virginia W. | In vivo screen using chemical inducers of dimerization |
| US20020168737A1 (en) | 2001-01-24 | 2002-11-14 | Cornish Virginia W. | Binding and catalysis screen for high throughput determination of protein function using chemical inducers of dimerization |
| PT2357006E (pt) * | 2002-07-31 | 2016-01-22 | Seattle Genetics Inc | Conjugados de fármacos e sua utilização para tratamento do cancro, de uma doença autoimune ou de uma doença infeciosa |
| US7429472B2 (en) | 2003-01-31 | 2008-09-30 | Promega Corporation | Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule |
| EP1594962B1 (en) | 2003-01-31 | 2014-08-27 | Promega Corporation | Covalent tethering of functional groups to proteins |
| KR100507796B1 (ko) | 2003-04-03 | 2005-08-17 | 한미약품 주식회사 | 생체내 반감기가 증가된 ｐｅｇ-생리활성 폴리펩티드 동종이량체 결합체 및 이의 제조방법 |
| US7425436B2 (en) | 2004-07-30 | 2008-09-16 | Promega Corporation | Covalent tethering of functional groups to proteins and substrates therefor |
| WO2007092579A2 (en) | 2006-02-08 | 2007-08-16 | Promega Corporation | Compositions and methods for capturing and analyzing cross-linked biomolecules |
| JP5420198B2 (ja) * | 2008-06-16 | 2014-02-19 | オリンパス株式会社 | タンパク質相互作用解析方法、ポリヌクレオチド、および、組成物 |
| KR100891456B1 (ko) | 2008-11-06 | 2009-04-01 | 씨지케이 주식회사 | 생리활성물질에 대한 세포내 표적물질을 검출하는 방법 및 장치 |
| CN102459579B (zh) * | 2009-05-01 | 2018-02-09 | 普罗梅加公司 | 具有增强的光输出的合成的刺虾萤光素酶 |
| ES2723773T3 (es) * | 2010-11-02 | 2019-09-02 | Promega Corp | Luciferasas derivadas de Oplophorus, nuevos sustratos de celenterazina y procedimientos de uso |
| KR102227321B1 (ko) | 2012-12-12 | 2021-03-12 | 프로메가 코포레이션 | 생체활성 제제의 세포 표적 포획을 위한 조성물 및 방법 |
| US11072811B2 (en) * | 2013-03-15 | 2021-07-27 | Promega Corporation | Substrates for covalent tethering of proteins to functional groups or solid surfaces |
| US10168323B2 (en) | 2013-03-15 | 2019-01-01 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
| EP3304078B1 (en) * | 2015-06-05 | 2022-08-31 | Promega Corporation | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements |
-
2013
- 2013-12-12 KR KR1020157018280A patent/KR102227321B1/ko active Active
- 2013-12-12 KR KR1020207024366A patent/KR102272233B1/ko active Active
- 2013-12-12 AU AU2013359160A patent/AU2013359160B2/en active Active
- 2013-12-12 WO PCT/US2013/074756 patent/WO2014093671A1/en not_active Ceased
- 2013-12-12 CA CA2894432A patent/CA2894432C/en active Active
- 2013-12-12 US US14/104,814 patent/US9551705B2/en active Active
- 2013-12-12 SG SG11201504520XA patent/SG11201504520XA/en unknown
- 2013-12-12 CN CN201380064237.XA patent/CN104853767B/zh active Active
- 2013-12-12 JP JP2015547559A patent/JP6484178B2/ja active Active
- 2013-12-12 EP EP13862430.9A patent/EP2931305B1/en active Active
- 2013-12-12 BR BR112015013715A patent/BR112015013715A2/pt not_active Application Discontinuation
-
2015
- 2015-06-04 IL IL239213A patent/IL239213B/en active IP Right Grant
-
2017
- 2017-01-10 US US15/402,879 patent/US10976312B2/en active Active
-
2019
- 2019-02-14 AU AU2019201035A patent/AU2019201035B9/en active Active
- 2019-02-15 JP JP2019025449A patent/JP6999589B2/ja active Active
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