JP2016214245A5 - - Google Patents
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- Publication number
- JP2016214245A5 JP2016214245A5 JP2016129697A JP2016129697A JP2016214245A5 JP 2016214245 A5 JP2016214245 A5 JP 2016214245A5 JP 2016129697 A JP2016129697 A JP 2016129697A JP 2016129697 A JP2016129697 A JP 2016129697A JP 2016214245 A5 JP2016214245 A5 JP 2016214245A5
- Authority
- JP
- Japan
- Prior art keywords
- eno1
- normalized
- level
- breast cancer
- rna transcript
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102100038910 Alpha-enolase Human genes 0.000 claims 36
- 101000882335 Homo sapiens Alpha-enolase Proteins 0.000 claims 36
- VLMZMRDOMOGGFA-WDBKCZKBSA-N festuclavine Chemical compound C1=CC([C@H]2C[C@H](CN(C)[C@@H]2C2)C)=C3C2=CNC3=C1 VLMZMRDOMOGGFA-WDBKCZKBSA-N 0.000 claims 36
- 238000000034 method Methods 0.000 claims 22
- 206010006187 Breast cancer Diseases 0.000 claims 15
- 208000026310 Breast neoplasm Diseases 0.000 claims 15
- 108091093088 Amplicon Proteins 0.000 claims 13
- 238000004393 prognosis Methods 0.000 claims 9
- 206010027476 Metastases Diseases 0.000 claims 5
- 238000004590 computer program Methods 0.000 claims 5
- 230000009401 metastasis Effects 0.000 claims 5
- 102000015694 estrogen receptors Human genes 0.000 claims 4
- 108010038795 estrogen receptors Proteins 0.000 claims 4
- 239000002299 complementary DNA Substances 0.000 claims 3
- 230000004083 survival effect Effects 0.000 claims 3
- 101001038034 Homo sapiens Lysophosphatidic acid receptor 6 Proteins 0.000 claims 2
- 102100040406 Lysophosphatidic acid receptor 6 Human genes 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 238000001574 biopsy Methods 0.000 claims 1
- 238000010839 reverse transcription Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26376309P | 2009-11-23 | 2009-11-23 | |
| US61/263,763 | 2009-11-23 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012540103A Division JP5964752B2 (ja) | 2009-11-23 | 2010-11-19 | 癌の臨床転帰を予測する方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018145578A Division JP7042717B2 (ja) | 2009-11-23 | 2018-08-02 | 癌の臨床転帰を予測する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016214245A JP2016214245A (ja) | 2016-12-22 |
| JP2016214245A5 true JP2016214245A5 (https=) | 2017-03-30 |
Family
ID=44060376
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012540103A Active JP5964752B2 (ja) | 2009-11-23 | 2010-11-19 | 癌の臨床転帰を予測する方法 |
| JP2016129697A Pending JP2016214245A (ja) | 2009-11-23 | 2016-06-30 | 癌の臨床転帰を予測する方法 |
| JP2018145578A Active JP7042717B2 (ja) | 2009-11-23 | 2018-08-02 | 癌の臨床転帰を予測する方法 |
| JP2020218527A Pending JP2021058207A (ja) | 2009-11-23 | 2020-12-28 | 癌の臨床転帰を予測する方法 |
| JP2022123265A Pending JP2022166064A (ja) | 2009-11-23 | 2022-08-02 | 癌の臨床転帰を予測する方法 |
| JP2022129605A Pending JP2022169647A (ja) | 2009-11-23 | 2022-08-16 | 癌の臨床転帰を予測する方法 |
| JP2023213416A Active JP7823012B2 (ja) | 2009-11-23 | 2023-12-18 | 癌の臨床転帰を予測する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012540103A Active JP5964752B2 (ja) | 2009-11-23 | 2010-11-19 | 癌の臨床転帰を予測する方法 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018145578A Active JP7042717B2 (ja) | 2009-11-23 | 2018-08-02 | 癌の臨床転帰を予測する方法 |
| JP2020218527A Pending JP2021058207A (ja) | 2009-11-23 | 2020-12-28 | 癌の臨床転帰を予測する方法 |
| JP2022123265A Pending JP2022166064A (ja) | 2009-11-23 | 2022-08-02 | 癌の臨床転帰を予測する方法 |
| JP2022129605A Pending JP2022169647A (ja) | 2009-11-23 | 2022-08-16 | 癌の臨床転帰を予測する方法 |
| JP2023213416A Active JP7823012B2 (ja) | 2009-11-23 | 2023-12-18 | 癌の臨床転帰を予測する方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20110123990A1 (https=) |
| EP (4) | EP3556867A1 (https=) |
| JP (7) | JP5964752B2 (https=) |
| AU (1) | AU2010321829B2 (https=) |
| CA (2) | CA3043089A1 (https=) |
| DK (1) | DK2504451T3 (https=) |
| ES (1) | ES2735993T3 (https=) |
| HU (1) | HUE044374T2 (https=) |
| IL (5) | IL219051A (https=) |
| MX (3) | MX391499B (https=) |
| NZ (1) | NZ599194A (https=) |
| PL (1) | PL2504451T3 (https=) |
| WO (1) | WO2011063274A2 (https=) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| CA2563074C (en) | 2004-04-09 | 2014-05-20 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| JP5020088B2 (ja) * | 2004-11-05 | 2012-09-05 | ジェノミック ヘルス， インコーポレイテッド | 遺伝子発現マーカーを使用する、化学療法に対する反応の予測 |
| WO2007123772A2 (en) | 2006-03-31 | 2007-11-01 | Genomic Health, Inc. | Genes involved in estrogen metabolism |
| RU2011102743A (ru) * | 2008-06-26 | 2012-08-10 | Дана-Фарбер Кэнсер Инститьют, Инк. (Us) | Характерные признаки и детерминанты, связанные с метастазированием, и способы их применения |
| US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
| DK177532B1 (en) | 2009-09-17 | 2013-09-08 | Bio Bedst Aps | Medical use of sPLA2 hydrolysable liposomes |
| CA3043089A1 (en) * | 2009-11-23 | 2011-05-26 | Genomic Health, Inc. | Methods to predict clinical outcome of cancer |
| EP3178944B1 (en) | 2010-01-11 | 2019-05-15 | Genomic Health, Inc. | Method to use gene expression to determine likelihood of clinical outcome of renal cancer |
| GB201009798D0 (en) | 2010-06-11 | 2010-07-21 | Immunovia Ab | Method,array and use thereof |
| EP3812469A1 (en) | 2010-07-07 | 2021-04-28 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| MX338883B (es) | 2010-07-27 | 2016-05-04 | Genomic Health Inc | Metodo para usar expresion de gen para determinar el pronostico de cancer de prostata. |
| US9605319B2 (en) | 2010-08-30 | 2017-03-28 | Myriad Genetics, Inc. | Gene signatures for cancer diagnosis and prognosis |
| US8916344B2 (en) | 2010-11-15 | 2014-12-23 | Exact Sciences Corporation | Methylation assay |
| US8361720B2 (en) | 2010-11-15 | 2013-01-29 | Exact Sciences Corporation | Real time cleavage assay |
| EP2691547A4 (en) * | 2011-03-26 | 2015-01-14 | Univ Oregon Health & Science | GENE EXPRESSION PREDICTORS FOR CANCER PROSPECTS |
| CA2840472A1 (en) * | 2011-06-22 | 2012-12-27 | Oncocyte Corporation | Methods and compositions for the treatment and diagnosis of bladder cancer |
| WO2013006495A2 (en) * | 2011-07-01 | 2013-01-10 | Dana-Farber Cancer Institute, Inc. | Methods of predicting prognosis in cancer |
| JP2014523589A (ja) | 2011-07-13 | 2014-09-11 | ザ マルチプル ミエローマ リサーチ ファウンデーション， インコーポレイテッド | データ収集及び配信のための方法 |
| KR20140057331A (ko) * | 2011-08-16 | 2014-05-12 | 온코사이트 코포레이션 | 유방암의 치료 및 진단을 위한 방법 및 조성물 |
| EP2776830B1 (en) * | 2011-11-08 | 2018-05-09 | Genomic Health, Inc. | Method of predicting breast cancer prognosis |
| JP5805518B2 (ja) | 2011-12-21 | 2015-11-04 | 株式会社島津製作所 | マルチプレックス大腸がんマーカーパネル |
| US8725426B2 (en) * | 2012-01-31 | 2014-05-13 | Genomic Health, Inc. | Gene expression profile algorithm and test for determining prognosis of prostate cancer |
| GB201206323D0 (en) * | 2012-04-10 | 2012-05-23 | Immunovia Ab | Methods and arrays for use in the same |
| WO2013159099A2 (en) * | 2012-04-20 | 2013-10-24 | Memorial Sloan-Kettering Cancer Center | Gene expression profiles associated with metastatic breast cancer |
| WO2014055398A1 (en) * | 2012-10-05 | 2014-04-10 | Siemens Healthcare Diagnostics Inc. | Method for detecting an increased risk or incidence of colorectal cancer |
| WO2014078700A1 (en) | 2012-11-16 | 2014-05-22 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| ES2859645T3 (es) | 2013-03-14 | 2021-10-04 | Mayo Found Medical Education & Res | Detección de neoplasia |
| KR101672531B1 (ko) * | 2013-04-18 | 2016-11-17 | 주식회사 젠큐릭스 | 조기 유방암 예후 예측 진단용 유전자 마커 및 이의 용도 |
| JP2016521979A (ja) | 2013-05-30 | 2016-07-28 | ジェノミック ヘルス， インコーポレイテッド | 腎臓がんを有する患者に対する再発スコアを計算するための遺伝子発現プロファイルアルゴリズム |
| WO2014195032A1 (en) * | 2013-06-07 | 2014-12-11 | Medical Prognosis Institute A/S | Methods and devices for predicting treatment efficacy of fulvestrant in cancer patients |
| US20170073763A1 (en) * | 2014-03-12 | 2017-03-16 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and Compositions for Assessing Patients with Non-small Cell Lung Cancer |
| EP3143160B1 (en) | 2014-05-13 | 2019-11-06 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| US10184154B2 (en) | 2014-09-26 | 2019-01-22 | Mayo Foundation For Medical Education And Research | Detecting cholangiocarcinoma |
| US10570457B2 (en) | 2014-09-26 | 2020-02-25 | Medical Prognosis Institute A/S | Methods for predicting drug responsiveness |
| WO2016092299A1 (en) * | 2014-12-09 | 2016-06-16 | Medical Research Council | Methods and kits for predicting the response to therapy of cancer |
| CN107532124B (zh) | 2015-03-27 | 2022-08-09 | 精密科学公司 | 检测食管疾病 |
| CN108138235B (zh) | 2015-08-31 | 2022-04-15 | 梅约医药教育及研究基金会 | 检测胃肿瘤 |
| AU2016343937B2 (en) | 2015-10-30 | 2023-01-19 | Exact Sciences Corporation | Multiplex amplification detection assay and isolation and detection of DNA from plasma |
| WO2017106790A1 (en) | 2015-12-18 | 2017-06-22 | Clear Gene, Inc. | Methods, compositions, kits and devices for rapid analysis of biological markers |
| CN110225984A (zh) * | 2016-09-07 | 2019-09-10 | 科技研究局 | 鉴别癌症风险的方法和治疗选择 |
| US9725769B1 (en) | 2016-10-07 | 2017-08-08 | Oncology Venture ApS | Methods for predicting drug responsiveness in cancer patients |
| AU2017258901A1 (en) | 2016-12-30 | 2018-07-19 | Allarity Therapeutics Europe ApS | Methods for predicting drug responsiveness in cancer patients |
| KR102892245B1 (ko) | 2017-01-27 | 2025-11-27 | 이그젝트 싸이언스 디블롭먼트 컴패니, 엘엘씨 | 메틸화된 dna 분석에 의한 결장 신조직형성의 검출 |
| WO2018212192A1 (ja) * | 2017-05-18 | 2018-11-22 | 京都府公立大学法人 | 癌の予後及び／又は転移可能性を評価する方法及びマーカー |
| US12275994B2 (en) * | 2017-06-22 | 2025-04-15 | Clear Gene, Inc. | Methods and compositions for the analysis of cancer biomarkers |
| EP3513280A4 (en) | 2017-11-13 | 2020-07-22 | The Multiple Myeloma Research Foundation, Inc. | INTEGRATED, MOLECULAR, OMIC, IMMUNOTHERAPY, METABOLIC, EPIGENETIC AND CLINICAL DATABASE |
| US10648025B2 (en) | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
| AU2019230200A1 (en) * | 2018-03-08 | 2020-10-29 | University Of Notre Dame Du Lac | Systems and methods for assessing colorectal cancer molecular subtype and risk of recurrence and for determining and administering treatment protocols based thereon |
| JP7199045B2 (ja) * | 2018-04-13 | 2023-01-05 | 国立大学法人大阪大学 | 乳癌の予後に関する情報の取得方法、乳癌の予後の判定装置及びコンピュータプログラム |
| WO2020059850A1 (ja) * | 2018-09-21 | 2020-03-26 | 国立大学法人東京大学 | がんの予後判定方法 |
| JP2019032334A (ja) * | 2018-10-03 | 2019-02-28 | イムノヴィア・アクチエボラーグ | 乳癌関連の疾患状態を決定する方法およびこの方法における使用のためのアレイ |
| KR102216645B1 (ko) * | 2018-10-29 | 2021-02-17 | 사회복지법인 삼성생명공익재단 | 폐암의 분자 아형 결정을 위한 바이오마커 패널 및 이의 용도 |
| WO2020118274A1 (en) * | 2018-12-08 | 2020-06-11 | Pfs Genomics, Inc. | Transcriptomic profiling for prognosis of breast cancer |
| CN113785076B (zh) * | 2019-05-03 | 2024-06-11 | 株式会社递希真 | 预测癌症预后的方法及其组合物 |
| CN111235270B (zh) * | 2019-08-29 | 2022-04-29 | 北京臻知医学科技有限责任公司 | 一种基于高通量测序法的肿瘤抗原表达检测引物及试剂盒 |
| US12165747B2 (en) * | 2020-01-23 | 2024-12-10 | The Broad Institute, Inc. | Molecular spatial mapping of metastatic tumor microenvironment |
| US20240117444A1 (en) * | 2021-02-12 | 2024-04-11 | Mammogen, Inc. | Biomarkers for the diagnosis of breast cancer |
| WO2022192128A2 (en) * | 2021-03-08 | 2022-09-15 | Castle Biosciences, Inc. | Determining prognosis and treatment based on clinical-pathologic factors and continuous multigene-expression profile scores |
| CN117116345B (zh) * | 2023-07-24 | 2025-09-16 | 中国人民解放军军事科学院军事医学研究院 | 一种基于基因调控网络构建患者生存网络的方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7171311B2 (en) * | 2001-06-18 | 2007-01-30 | Rosetta Inpharmatics Llc | Methods of assigning treatment to breast cancer patients |
| JP2005500832A (ja) * | 2001-06-18 | 2005-01-13 | ロゼッタ・インファーマティクス・インコーポレーテッド | 乳癌患者の診断および予後 |
| WO2003004989A2 (en) * | 2001-06-21 | 2003-01-16 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
| CA2992643C (en) * | 2002-03-13 | 2019-06-18 | Genomic Health, Inc. | Gene expression profiling in biopsied tumor tissues |
| US20040067234A1 (en) * | 2002-07-11 | 2004-04-08 | Paz Einat | Isocitrate dehydrogenase and uses thereof |
| US20040231909A1 (en) * | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| US7526387B2 (en) * | 2003-07-10 | 2009-04-28 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
| US8019552B2 (en) * | 2004-03-05 | 2011-09-13 | The Netherlands Cancer Institute | Classification of breast cancer patients using a combination of clinical criteria and informative genesets |
| WO2006037485A2 (en) * | 2004-09-30 | 2006-04-13 | Bayer Healthcare Ag | Methods and kits for the prediction of therapeutic success and recurrence free survival in cancer therapy |
| US20080193938A1 (en) * | 2005-04-01 | 2008-08-14 | Yu Kun | Materials And Methods Relating To Breast Cancer Classification |
| WO2006133460A2 (en) * | 2005-06-09 | 2006-12-14 | Yale University | Methods for diagnosing and treating breast cancer based on a her/er ratio |
| WO2006135886A2 (en) * | 2005-06-13 | 2006-12-21 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| EP1907858A4 (en) * | 2005-06-13 | 2009-04-08 | Univ Michigan | COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER |
| TWI304443B (en) * | 2005-12-30 | 2008-12-21 | Nat Health Research Institutes | Alpha-enolase specific antibody and method of use |
| WO2007123772A2 (en) * | 2006-03-31 | 2007-11-01 | Genomic Health, Inc. | Genes involved in estrogen metabolism |
| US20100234292A1 (en) * | 2007-04-16 | 2010-09-16 | Ipsogen | Methods of assessing a propensity of clinical outcome for a female mammal suffering from breast cancer |
| WO2008150512A2 (en) * | 2007-06-04 | 2008-12-11 | University Of Louisville Research Foundation, Inc. | Methods for identifying an increased likelihood of recurrence of breast cancer |
| WO2009095319A1 (en) * | 2008-01-28 | 2009-08-06 | Siemens Healthcare Diagnostics Gmbh | Cancer prognosis by majority voting |
| WO2009132928A2 (en) * | 2008-05-02 | 2009-11-05 | Siemens Healthcare Diagnostics Gmbh | Molecular markers for cancer prognosis |
| DK2568053T3 (da) * | 2008-05-12 | 2014-07-21 | Genomic Health Inc | Tests til forudsigelse af cancerpatienters respons på forskellige kemoterapeutiske behandlingsmuligheder |
| CA3043089A1 (en) * | 2009-11-23 | 2011-05-26 | Genomic Health, Inc. | Methods to predict clinical outcome of cancer |
-
2010
- 2010-11-19 CA CA3043089A patent/CA3043089A1/en not_active Withdrawn
- 2010-11-19 CA CA2776751A patent/CA2776751C/en active Active
- 2010-11-19 HU HUE10832289 patent/HUE044374T2/hu unknown
- 2010-11-19 EP EP19175741.8A patent/EP3556867A1/en not_active Withdrawn
- 2010-11-19 MX MX2019003811A patent/MX391499B/es unknown
- 2010-11-19 ES ES10832289T patent/ES2735993T3/es active Active
- 2010-11-19 MX MX2016003089A patent/MX363817B/es unknown
- 2010-11-19 NZ NZ599194A patent/NZ599194A/en unknown
- 2010-11-19 AU AU2010321829A patent/AU2010321829B2/en active Active
- 2010-11-19 PL PL10832289T patent/PL2504451T3/pl unknown
- 2010-11-19 US US12/950,732 patent/US20110123990A1/en not_active Abandoned
- 2010-11-19 DK DK10832289.2T patent/DK2504451T3/da active
- 2010-11-19 EP EP20177718.2A patent/EP3739060A1/en not_active Withdrawn
- 2010-11-19 JP JP2012540103A patent/JP5964752B2/ja active Active
- 2010-11-19 EP EP23213439.5A patent/EP4350001A3/en active Pending
- 2010-11-19 EP EP10832289.2A patent/EP2504451B1/en active Active
- 2010-11-19 MX MX2012005822A patent/MX337650B/es active IP Right Grant
- 2010-11-19 WO PCT/US2010/057490 patent/WO2011063274A2/en not_active Ceased
-
2012
- 2012-04-04 IL IL219051A patent/IL219051A/en active IP Right Grant
-
2016
- 2016-06-30 JP JP2016129697A patent/JP2016214245A/ja active Pending
- 2016-11-23 IL IL249159A patent/IL249159A0/en unknown
-
2017
- 2017-02-03 US US15/423,977 patent/US20170211154A1/en not_active Abandoned
-
2018
- 2018-01-21 IL IL257063A patent/IL257063B/en active IP Right Grant
- 2018-08-02 JP JP2018145578A patent/JP7042717B2/ja active Active
-
2019
- 2019-01-03 IL IL264072A patent/IL264072B/en active IP Right Grant
- 2019-01-09 US US16/243,207 patent/US20190241967A1/en not_active Abandoned
-
2020
- 2020-08-04 IL IL276487A patent/IL276487B/en unknown
- 2020-09-11 US US17/018,143 patent/US20210062275A1/en not_active Abandoned
- 2020-12-28 JP JP2020218527A patent/JP2021058207A/ja active Pending
-
2022
- 2022-08-02 JP JP2022123265A patent/JP2022166064A/ja active Pending
- 2022-08-16 JP JP2022129605A patent/JP2022169647A/ja active Pending
-
2023
- 2023-12-18 JP JP2023213416A patent/JP7823012B2/ja active Active
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