JP2016169229A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016169229A5 JP2016169229A5 JP2016120503A JP2016120503A JP2016169229A5 JP 2016169229 A5 JP2016169229 A5 JP 2016169229A5 JP 2016120503 A JP2016120503 A JP 2016120503A JP 2016120503 A JP2016120503 A JP 2016120503A JP 2016169229 A5 JP2016169229 A5 JP 2016169229A5
- Authority
- JP
- Japan
- Prior art keywords
- pik3ca
- subject
- mutation
- neratinib
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28582109P | 2009-12-11 | 2009-12-11 | |
| US61/285,821 | 2009-12-11 | ||
| US28787209P | 2009-12-18 | 2009-12-18 | |
| US61/287,872 | 2009-12-18 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015051863A Division JP2015110669A (ja) | 2009-12-11 | 2015-03-16 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017038956A Division JP2017101072A (ja) | 2009-12-11 | 2017-03-02 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016169229A JP2016169229A (ja) | 2016-09-23 |
| JP2016169229A5 true JP2016169229A5 (enExample) | 2017-04-06 |
Family
ID=43628745
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010273484A Withdrawn JP2011121944A (ja) | 2009-12-11 | 2010-12-08 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2015051863A Pending JP2015110669A (ja) | 2009-12-11 | 2015-03-16 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2016120503A Withdrawn JP2016169229A (ja) | 2009-12-11 | 2016-06-17 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2017038956A Withdrawn JP2017101072A (ja) | 2009-12-11 | 2017-03-02 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2018246698A Withdrawn JP2019052187A (ja) | 2009-12-11 | 2018-12-28 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2020119091A Withdrawn JP2020169212A (ja) | 2009-12-11 | 2020-07-10 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2021192872A Pending JP2022022296A (ja) | 2009-12-11 | 2021-11-29 | ホスファチジルイノシトール－３－キナーゼ経路バイオマーカー |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010273484A Withdrawn JP2011121944A (ja) | 2009-12-11 | 2010-12-08 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2015051863A Pending JP2015110669A (ja) | 2009-12-11 | 2015-03-16 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017038956A Withdrawn JP2017101072A (ja) | 2009-12-11 | 2017-03-02 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2018246698A Withdrawn JP2019052187A (ja) | 2009-12-11 | 2018-12-28 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2020119091A Withdrawn JP2020169212A (ja) | 2009-12-11 | 2020-07-10 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2021192872A Pending JP2022022296A (ja) | 2009-12-11 | 2021-11-29 | ホスファチジルイノシトール－３－キナーゼ経路バイオマーカー |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US20130189274A1 (enExample) |
| EP (2) | EP3575413A1 (enExample) |
| JP (7) | JP2011121944A (enExample) |
| CA (1) | CA2783743C (enExample) |
| WO (1) | WO2011070499A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108421044A (zh) | 2005-02-03 | 2018-08-21 | 综合医院公司 | 治疗吉非替尼耐药性癌症的方法 |
| BRPI0618042A2 (pt) | 2005-11-04 | 2011-08-16 | Wyeth Corp | usos de uma rapamicina e de uma herceptina, produto, pacote farmacêutico, e, composição farmacêutica |
| US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
| CN102641270A (zh) | 2008-06-17 | 2012-08-22 | 惠氏有限责任公司 | 含有hki-272和长春瑞滨的抗肿瘤组合 |
| US8669273B2 (en) | 2008-08-04 | 2014-03-11 | Wyeth Llc | Antineoplastic combinations of 4-anilino-3-cyanoquinolines and capecitabine |
| IL264349B2 (en) | 2009-04-06 | 2024-01-01 | Wyeth Llc | Regimen comprising neratinib for the treatment of cancer |
| NZ599762A (en) | 2009-11-09 | 2014-07-25 | Wyeth Llc | Coated drug spheroids and uses thereof for eliminating or reducing conditions such as emesis and diarrhea |
| CA2843222A1 (en) * | 2011-07-28 | 2013-01-31 | Genentech, Inc. | Pik3ca h1047r knock-in non-human animal breast cancer model |
| WO2013083810A1 (en) * | 2011-12-09 | 2013-06-13 | F. Hoffmann-La Roche Ag | Identification of non-responders to her2 inhibitors |
| KR101915942B1 (ko) * | 2012-06-08 | 2018-11-06 | 에프. 호프만-라 로슈 아게 | 암의 치료를 위한 포스포이노시타이드 3 키나제 억제제 화합물 및 화학치료제의 돌연변이체 선택성 및 조합물 |
| CN105274188A (zh) * | 2014-05-29 | 2016-01-27 | 北京雅康博生物科技有限公司 | Pik3ca基因突变检测试剂盒 |
| NZ737362A (en) * | 2015-05-15 | 2022-07-01 | Memorial Sloan Kettering Cancer Center | Use of phosphoinositide 3-kinase inhibitors for treatment of vascular malformations |
| US10672505B2 (en) | 2015-06-03 | 2020-06-02 | General Electric Company | Biological data annotation and visualization |
| US9953133B2 (en) | 2015-06-03 | 2018-04-24 | General Electric Company | Biological data annotation and visualization |
| US9607375B2 (en) * | 2015-06-03 | 2017-03-28 | Eileen B. Gallagher | Biological data annotation and visualization |
| KR20190054826A (ko) * | 2017-11-14 | 2019-05-22 | 한미약품 주식회사 | 암의 포지오티닙 치료에 대한 반응을 나타내는 바이오마커 및 그의 용도 |
| KR102871791B1 (ko) | 2018-09-10 | 2025-10-15 | 미라티 테라퓨틱스, 인크. | 병용 요법 |
| IT201800010730A1 (it) * | 2018-11-30 | 2020-05-30 | Univ Degli Studi Milano | Metodo per classificare pazienti affetti da tumore alla mammella idonei per immunoterapia |
| IL285020B2 (en) | 2019-02-06 | 2025-11-01 | Venthera Inc | Topical phosphoinositide 3-kinase inhibitors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7399865B2 (en) | 2003-09-15 | 2008-07-15 | Wyeth | Protein tyrosine kinase enzyme inhibitors |
| WO2006098978A1 (en) * | 2005-03-09 | 2006-09-21 | Abbott Laboratories | Diagnostics method for identifying candidate patients for the treatment with trastuzumab |
| EP1899463A4 (en) * | 2005-05-09 | 2009-11-25 | Ariad Pharma Inc | BIOMARKERS FOR EVALUATING THE PROBABILITY OF SENSITIVITY OF A TUMOR AGAINST A MTOR INHIBITOR |
| BRPI0618042A2 (pt) | 2005-11-04 | 2011-08-16 | Wyeth Corp | usos de uma rapamicina e de uma herceptina, produto, pacote farmacêutico, e, composição farmacêutica |
| EP1978106A1 (en) * | 2007-04-07 | 2008-10-08 | Universitätsklinikum Hamburg-Eppendorf | Detection of ESR1 amplification in endometrium cancer and ovary cancer |
| ES2529790T3 (es) * | 2007-04-13 | 2015-02-25 | Dana-Farber Cancer Institute, Inc. | Métodos de tratamiento de cáncer resistente a agentes terapéuticos de ERBB |
| US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
-
2010
- 2010-12-06 EP EP19170821.3A patent/EP3575413A1/en active Pending
- 2010-12-06 US US13/514,556 patent/US20130189274A1/en not_active Abandoned
- 2010-12-06 CA CA2783743A patent/CA2783743C/en active Active
- 2010-12-06 EP EP10805335A patent/EP2510121A1/en not_active Ceased
- 2010-12-06 WO PCT/IB2010/055604 patent/WO2011070499A1/en not_active Ceased
- 2010-12-08 JP JP2010273484A patent/JP2011121944A/ja not_active Withdrawn
-
2015
- 2015-03-16 JP JP2015051863A patent/JP2015110669A/ja active Pending
-
2016
- 2016-04-14 US US15/099,429 patent/US20160222467A1/en not_active Abandoned
- 2016-06-17 JP JP2016120503A patent/JP2016169229A/ja not_active Withdrawn
-
2017
- 2017-03-02 JP JP2017038956A patent/JP2017101072A/ja not_active Withdrawn
-
2018
- 2018-12-28 JP JP2018246698A patent/JP2019052187A/ja not_active Withdrawn
-
2019
- 2019-05-17 US US16/416,083 patent/US20190271047A1/en not_active Abandoned
-
2020
- 2020-07-10 JP JP2020119091A patent/JP2020169212A/ja not_active Withdrawn
-
2021
- 2021-11-09 US US17/522,637 patent/US20220170107A1/en not_active Abandoned
- 2021-11-29 JP JP2021192872A patent/JP2022022296A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Molinari et al. | Heterogeneity in colorectal cancer: a challenge for personalized medicine? | |
| US20230146253A1 (en) | Methods related to bronchial premalignant lesion severity and progression | |
| Sukawa et al. | Alterations in the human epidermal growth factor receptor 2-phosphatidylinositol 3-kinase-v-Akt pathway in gastric cancer | |
| EP2944961A1 (en) | Markers for cancer prognosis and therapy and methods of use | |
| Sung et al. | FGFR3 overexpression is prognostic of adverse outcome for muscle-invasive bladder carcinoma treated with adjuvant chemotherapy | |
| Schulze et al. | RELN signaling modulates glioblastoma growth and substrate‐dependent migration | |
| Xu et al. | KRAS and PIK3CA but not BRAF genes are frequently mutated in Chinese cholangiocarcinoma patients | |
| EP3140427A2 (en) | Biomarkers for response to pi3k inhibitors | |
| US20140134158A1 (en) | Kras mutations and resistance to anti-egfr treatment | |
| CN105705658A (zh) | 随时间检测疾病中的突变 | |
| Clemens et al. | A modified Phenol-chloroform extraction method for isolating circulating cell free DNA of tumor patients. | |
| JP2023508947A (ja) | 循環腫瘍ｄｎａの分析を介した分子疾患評価のための方法およびシステム | |
| JP2013178260A5 (enExample) | ||
| JP2014503180A5 (enExample) | ||
| Sohn et al. | Single-nucleotide polymorphisms in the vascular endothelial growth factor pathway and outcomes of patients treated with first-line cytotoxic chemotherapy combined with bevacizumab for advanced colorectal cancer | |
| CN110452986A (zh) | 一种检测结直肠癌相关基因变异的引物及其应用 | |
| CN113056267A (zh) | Plk1靶磷酸化状态以及用plk1抑制剂治疗癌症 | |
| Yao et al. | Integration of liquid biopsy and immunotherapy: opening a new era in colorectal cancer treatment | |
| WO2020092998A1 (en) | Identification of pde3 modulator responsive cancers | |
| Agirre-Lizaso et al. | Targeting the heterogeneous tumour-associated macrophages in hepatocellular carcinoma | |
| CA2819080A1 (en) | Agtr1 as a marker for bevacizumab combination therapies | |
| Nagayama et al. | Precision medicine for colorectal cancer with liquid biopsy and immunotherapy | |
| WO2017197351A1 (en) | Methods for identifying clonal mutations and treating cancer | |
| Berardi et al. | Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy | |
| US20230332246A1 (en) | Methods for characterizing biological samples |