JP2016169229A5 - - Google Patents
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- Publication number
- JP2016169229A5 JP2016169229A5 JP2016120503A JP2016120503A JP2016169229A5 JP 2016169229 A5 JP2016169229 A5 JP 2016169229A5 JP 2016120503 A JP2016120503 A JP 2016120503A JP 2016120503 A JP2016120503 A JP 2016120503A JP 2016169229 A5 JP2016169229 A5 JP 2016169229A5
- Authority
- JP
- Japan
- Prior art keywords
- pik3ca
- subject
- mutation
- neratinib
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28582109P | 2009-12-11 | 2009-12-11 | |
| US61/285,821 | 2009-12-11 | ||
| US28787209P | 2009-12-18 | 2009-12-18 | |
| US61/287,872 | 2009-12-18 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015051863A Division JP2015110669A (ja) | 2009-12-11 | 2015-03-16 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017038956A Division JP2017101072A (ja) | 2009-12-11 | 2017-03-02 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016169229A JP2016169229A (ja) | 2016-09-23 |
| JP2016169229A5 true JP2016169229A5 (enExample) | 2017-04-06 |
Family
ID=43628745
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010273484A Withdrawn JP2011121944A (ja) | 2009-12-11 | 2010-12-08 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2015051863A Pending JP2015110669A (ja) | 2009-12-11 | 2015-03-16 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2016120503A Withdrawn JP2016169229A (ja) | 2009-12-11 | 2016-06-17 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2017038956A Withdrawn JP2017101072A (ja) | 2009-12-11 | 2017-03-02 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2018246698A Withdrawn JP2019052187A (ja) | 2009-12-11 | 2018-12-28 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2020119091A Withdrawn JP2020169212A (ja) | 2009-12-11 | 2020-07-10 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2021192872A Pending JP2022022296A (ja) | 2009-12-11 | 2021-11-29 | ホスファチジルイノシトール－３－キナーゼ経路バイオマーカー |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010273484A Withdrawn JP2011121944A (ja) | 2009-12-11 | 2010-12-08 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2015051863A Pending JP2015110669A (ja) | 2009-12-11 | 2015-03-16 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017038956A Withdrawn JP2017101072A (ja) | 2009-12-11 | 2017-03-02 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2018246698A Withdrawn JP2019052187A (ja) | 2009-12-11 | 2018-12-28 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2020119091A Withdrawn JP2020169212A (ja) | 2009-12-11 | 2020-07-10 | ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー |
| JP2021192872A Pending JP2022022296A (ja) | 2009-12-11 | 2021-11-29 | ホスファチジルイノシトール－３－キナーゼ経路バイオマーカー |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US20130189274A1 (enExample) |
| EP (2) | EP2510121A1 (enExample) |
| JP (7) | JP2011121944A (enExample) |
| CA (1) | CA2783743C (enExample) |
| WO (1) | WO2011070499A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006084058A2 (en) | 2005-02-03 | 2006-08-10 | The General Hospital Corporation | Method for treating gefitinib resistant cancer |
| CN103110948A (zh) | 2005-11-04 | 2013-05-22 | 惠氏公司 | mTOR抑制剂、赫赛汀和/或HKI-272的抗肿瘤组合 |
| US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
| DK2656844T3 (en) | 2008-06-17 | 2015-03-02 | Wyeth Llc | ANTINEOPLASTIC COMBINATIONS CONTAINING HKI-272 AND VINORELBINE |
| ES2614912T3 (es) | 2008-08-04 | 2017-06-02 | Wyeth Llc | Combinaciones antineoplásicas de 4-anilino-3-cianoquinolinas y capecitabina |
| PT3000467T (pt) | 2009-04-06 | 2023-03-30 | Wyeth Llc | Regime de tratamento utilizando neratinib para o cancro de mama |
| ES2729677T3 (es) | 2009-11-09 | 2019-11-05 | Wyeth Llc | Esferoides de fármacos recubiertos y sus usos para eliminar o reducir condiciones, como la emesis y la diarrea |
| RU2014107713A (ru) * | 2011-07-28 | 2015-09-10 | Дженентек, Инк | Модель рака молочной железы у животных, кроме человека, с активируемым pik3ca h1047r |
| US9376715B2 (en) | 2011-12-09 | 2016-06-28 | Roche Molecular Systems, Inc | Methods for detecting mutations in the catalytic subunit of the phosphoinositol-3 kinase (PIK3CA) gene |
| JP5933830B2 (ja) * | 2012-06-08 | 2016-06-15 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 癌の処置用のホスホイノシチド３キナーゼ阻害化合物と化学療法剤との変異体選択性及び組み合わせ |
| CN105274188A (zh) * | 2014-05-29 | 2016-01-27 | 北京雅康博生物科技有限公司 | Pik3ca基因突变检测试剂盒 |
| AU2016265844B2 (en) | 2015-05-15 | 2021-02-11 | Memorial Sloan-Kettering Cancer Center | Use of phosphoinositide 3-kinase inhibitors for treatment of vascular malformations |
| US9953133B2 (en) | 2015-06-03 | 2018-04-24 | General Electric Company | Biological data annotation and visualization |
| US10672505B2 (en) | 2015-06-03 | 2020-06-02 | General Electric Company | Biological data annotation and visualization |
| US9607375B2 (en) * | 2015-06-03 | 2017-03-28 | Eileen B. Gallagher | Biological data annotation and visualization |
| KR20190054826A (ko) * | 2017-11-14 | 2019-05-22 | 한미약품 주식회사 | 암의 포지오티닙 치료에 대한 반응을 나타내는 바이오마커 및 그의 용도 |
| AU2019340366B2 (en) * | 2018-09-10 | 2025-01-02 | Mirati Therapeutics, Inc. | Combination therapies |
| IT201800010730A1 (it) * | 2018-11-30 | 2020-05-30 | Univ Degli Studi Milano | Metodo per classificare pazienti affetti da tumore alla mammella idonei per immunoterapia |
| CA3127686A1 (en) | 2019-02-06 | 2020-08-13 | Venthera, Inc. | Topical phosphoinositide 3-kinase inhibitors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7399865B2 (en) | 2003-09-15 | 2008-07-15 | Wyeth | Protein tyrosine kinase enzyme inhibitors |
| JP5336174B2 (ja) * | 2005-03-09 | 2013-11-06 | アボット・ラボラトリーズ | トラスツズマブによる治療の候補患者を確認するための診断方法 |
| EP1899463A4 (en) * | 2005-05-09 | 2009-11-25 | Ariad Pharma Inc | BIOMARKERS FOR EVALUATING THE PROBABILITY OF SENSITIVITY OF A TUMOR AGAINST A MTOR INHIBITOR |
| CN103110948A (zh) | 2005-11-04 | 2013-05-22 | 惠氏公司 | mTOR抑制剂、赫赛汀和/或HKI-272的抗肿瘤组合 |
| EP1978106A1 (en) * | 2007-04-07 | 2008-10-08 | Universitätsklinikum Hamburg-Eppendorf | Detection of ESR1 amplification in endometrium cancer and ovary cancer |
| CA2683559C (en) * | 2007-04-13 | 2019-09-24 | Dana Farber Cancer Institute, Inc. | Methods for treating cancer resistant to erbb therapeutics |
| US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
-
2010
- 2010-12-06 WO PCT/IB2010/055604 patent/WO2011070499A1/en not_active Ceased
- 2010-12-06 US US13/514,556 patent/US20130189274A1/en not_active Abandoned
- 2010-12-06 EP EP10805335A patent/EP2510121A1/en not_active Ceased
- 2010-12-06 CA CA2783743A patent/CA2783743C/en active Active
- 2010-12-06 EP EP19170821.3A patent/EP3575413A1/en active Pending
- 2010-12-08 JP JP2010273484A patent/JP2011121944A/ja not_active Withdrawn
-
2015
- 2015-03-16 JP JP2015051863A patent/JP2015110669A/ja active Pending
-
2016
- 2016-04-14 US US15/099,429 patent/US20160222467A1/en not_active Abandoned
- 2016-06-17 JP JP2016120503A patent/JP2016169229A/ja not_active Withdrawn
-
2017
- 2017-03-02 JP JP2017038956A patent/JP2017101072A/ja not_active Withdrawn
-
2018
- 2018-12-28 JP JP2018246698A patent/JP2019052187A/ja not_active Withdrawn
-
2019
- 2019-05-17 US US16/416,083 patent/US20190271047A1/en not_active Abandoned
-
2020
- 2020-07-10 JP JP2020119091A patent/JP2020169212A/ja not_active Withdrawn
-
2021
- 2021-11-09 US US17/522,637 patent/US20220170107A1/en not_active Abandoned
- 2021-11-29 JP JP2021192872A patent/JP2022022296A/ja active Pending
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