JP2015528515A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015528515A5 JP2015528515A5 JP2015532164A JP2015532164A JP2015528515A5 JP 2015528515 A5 JP2015528515 A5 JP 2015528515A5 JP 2015532164 A JP2015532164 A JP 2015532164A JP 2015532164 A JP2015532164 A JP 2015532164A JP 2015528515 A5 JP2015528515 A5 JP 2015528515A5
- Authority
- JP
- Japan
- Prior art keywords
- hydroxide
- group
- magnesium
- composition
- calcium carbonate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims description 17
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 16
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical group [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 12
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 8
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 claims description 8
- 239000000347 magnesium hydroxide Substances 0.000 claims description 8
- 229910001862 magnesium hydroxide Inorganic materials 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 7
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims description 6
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 claims description 6
- 239000001095 magnesium carbonate Substances 0.000 claims description 6
- 229910000021 magnesium carbonate Inorganic materials 0.000 claims description 6
- 210000003238 esophagus Anatomy 0.000 claims description 5
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 6
- 239000002562 thickening agent Substances 0.000 claims 5
- 150000008044 alkali metal hydroxides Chemical class 0.000 claims 4
- 229920002785 Croscarmellose sodium Polymers 0.000 claims 3
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical group [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 3
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims 3
- 229960001681 croscarmellose sodium Drugs 0.000 claims 3
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 claims 3
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 3
- 239000008108 microcrystalline cellulose Substances 0.000 claims 3
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 3
- 230000001953 sensory effect Effects 0.000 claims 3
- 239000000230 xanthan gum Substances 0.000 claims 3
- 235000010493 xanthan gum Nutrition 0.000 claims 3
- 229920001285 xanthan gum Polymers 0.000 claims 3
- 229940082509 xanthan gum Drugs 0.000 claims 3
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 239000000839 emulsion Substances 0.000 claims 2
- 230000005484 gravity Effects 0.000 claims 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 2
- 208000014674 injury Diseases 0.000 claims 2
- 210000000111 lower esophageal sphincter Anatomy 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 230000008733 trauma Effects 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 210000004211 gastric acid Anatomy 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 230000000451 tissue damage Effects 0.000 claims 1
- 231100000827 tissue damage Toxicity 0.000 claims 1
- 210000001942 upper esophageal sphincter Anatomy 0.000 claims 1
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 229940031958 magnesium carbonate hydroxide Drugs 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261702611P | 2012-09-18 | 2012-09-18 | |
| US61/702,611 | 2012-09-18 | ||
| US14/027,937 | 2013-09-16 | ||
| US14/027,937 US9636360B2 (en) | 2012-09-18 | 2013-09-16 | Method and composition for treating gastro-esophageal disorders |
| PCT/US2013/060322 WO2014047127A1 (en) | 2012-09-18 | 2013-09-18 | Method and composition for treating gastro-esophageal disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015528515A JP2015528515A (ja) | 2015-09-28 |
| JP2015528515A5 true JP2015528515A5 (enExample) | 2016-11-10 |
| JP6275725B2 JP6275725B2 (ja) | 2018-02-07 |
Family
ID=50274730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015532164A Expired - Fee Related JP6275725B2 (ja) | 2012-09-18 | 2013-09-18 | 胃食道疾患を治療するための方法および組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9636360B2 (enExample) |
| EP (1) | EP2919856A4 (enExample) |
| JP (1) | JP6275725B2 (enExample) |
| CA (1) | CA2885218C (enExample) |
| WO (1) | WO2014047127A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9636360B2 (en) * | 2012-09-18 | 2017-05-02 | pH Science Holdings, Inc | Method and composition for treating gastro-esophageal disorders |
| CN105943552A (zh) * | 2016-06-17 | 2016-09-21 | 王枝宝 | 一种氢氧化钾的医药用途 |
| IT201600121617A1 (it) * | 2016-11-30 | 2018-05-30 | Nekkar Lab Srl | Composizione per il trattamento del reflusso gastroesofageo |
| IT201600121601A1 (it) * | 2016-11-30 | 2018-05-30 | Nekkar Lab Srl | Composizione orale per il trattamento del reflusso gastroesofageo e del reflusso laringo-faringeo |
| US20250000899A1 (en) * | 2022-09-07 | 2025-01-02 | Ph Science Holdings, Inc. | Methods and Compositions For Increasing Mitochondrial Biogenesis |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW209174B (enExample) | 1991-04-19 | 1993-07-11 | Takeda Pharm Industry Co Ltd | |
| GB9504599D0 (en) | 1995-03-03 | 1995-04-26 | Reckitt & Colmann Prod Ltd | Improvements in or relating to organic compositions |
| US6066342A (en) | 1995-12-22 | 2000-05-23 | Tamer International, Ltd. | Antacid composition |
| US6395307B1 (en) | 1997-04-30 | 2002-05-28 | Reckitt Benckiser (Uk) Limited | Pourable alginate compositions |
| US20020009478A1 (en) | 1998-08-24 | 2002-01-24 | Douglas Joseph Dobrozsi | Oral liquid mucoadhesive compositions |
| GB9910212D0 (en) | 1999-05-05 | 1999-06-30 | Reckitt & Colmann Prod Ltd | Improvements in or relating to organic compositions |
| US6669928B1 (en) * | 1999-05-13 | 2003-12-30 | Tamer International, Ltd. | Periodontal composition |
| US20060183776A9 (en) * | 2000-03-03 | 2006-08-17 | Eisai Co., Ltd. | Liquid dosage formulations of donepezil |
| US20030175360A1 (en) * | 2002-02-22 | 2003-09-18 | Renzo Luzzatti | Symptomatic relief of gastrointestinal disorders |
| WO2005027939A1 (en) | 2003-08-21 | 2005-03-31 | Access Pharmaceuticals, Inc. | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
| US7901717B1 (en) * | 2005-06-03 | 2011-03-08 | Scientific Food Solutions, Llc | Alkalizing compositions and methods for using the same |
| US20070218126A1 (en) * | 2006-03-16 | 2007-09-20 | Tamer Laboratories, Inc. | Compositions and Methods for Reducing Inflammation and Pain Associated with Acidosis |
| WO2008100539A1 (en) * | 2007-02-12 | 2008-08-21 | Michalis Nicolaou | Treatment of copd, gastro-esophageal reflux disease (gerd), food allergies and other gastrointestinal conditions and disorders ameliorated by proper histamine management using a combination of histidine decarboxylase inhibitors, lra drugs, anti-h1 and/or anti-h2 drugs |
| US20090148530A1 (en) | 2007-12-08 | 2009-06-11 | Jamie Koufman | Method for prevention and treatment of reflux injury in the aerodigestive tract and laryngopharynx caused by pepsin |
| CN102448440A (zh) | 2009-03-26 | 2012-05-09 | 普马特里克斯公司 | 治疗呼吸道感染的医药调配物及方法 |
| RU2465912C9 (ru) * | 2011-10-31 | 2013-11-20 | Закрытое Акционерное Общество "Велес Фарма" | Фармацевтическая композиция на основе наномицелл, содержащих эпигаллокатехингаллат, и ее применение для лечения атопического дерматита, болезни крона, аденомиоза и гиперпластических заболеваний предстательной железы |
| US9636360B2 (en) * | 2012-09-18 | 2017-05-02 | pH Science Holdings, Inc | Method and composition for treating gastro-esophageal disorders |
-
2013
- 2013-09-16 US US14/027,937 patent/US9636360B2/en active Active
- 2013-09-18 EP EP13838573.7A patent/EP2919856A4/en not_active Withdrawn
- 2013-09-18 JP JP2015532164A patent/JP6275725B2/ja not_active Expired - Fee Related
- 2013-09-18 CA CA2885218A patent/CA2885218C/en active Active
- 2013-09-18 WO PCT/US2013/060322 patent/WO2014047127A1/en not_active Ceased
-
2017
- 2017-05-01 US US15/583,791 patent/US11090329B2/en active Active - Reinstated
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015528515A5 (enExample) | ||
| CL2018001474A1 (es) | Mezcla seca que comprende sal de alginato; goma vegetal hidrocoloide de galactamanano; y almidon para la fabricacion de una composicion de alginato para envoltura de productos alimenticios que ademas comprende: poliol; humo liquido; y un agente amortiguador tal como glucono-delta-lactona, ácido acético, y carbonato de sodio (divisional de 408-2017). | |
| RU2011123377A (ru) | ТВЕРДАЯ КОМПОЗИЦИЯ ДЛЯ КОНТРОЛИРУЕМОГО ВЫСВОБОЖДЕНИЯ АКТИВНЫХ ИОНИЗИРУЕМЫХ АГЕНТОВ, ХАРАКТЕРИЗУЮЩИХСЯ НИЗКОЙ РАСТВОРИМОСТЬЮ В ВОДЕ ПРИ НИЗКИХ ЗНАЧЕНИЯХ pН, И СПОСОБЫ ЕЕ ПРИМЕНЕНИЯ | |
| IL203448A (en) | History of azabiphenylaminobenzoic acid for use in the treatment or prevention of a pathological condition or disease susceptible to reduction by dhodh inhibition and medicinal preparations containing them | |
| JP2012532093A5 (enExample) | ||
| RU2015132974A (ru) | Слезозаменитель, содержащий гиалуронат натрия и карбоксиметилцеллюлозу | |
| JP2014218522A5 (enExample) | ||
| MX2013005529A (es) | Composicion conservadora concentrada acuosa y estable de acido deshidroacetico (dha) y metilisotiazolinona. | |
| JP2010540619A5 (enExample) | ||
| JP2016503058A5 (enExample) | ||
| WO2016210003A3 (en) | 17-hydroxyprogesterone ester-containing oral compositions and related methods | |
| MX2011013648A (es) | Nuevos compuestos, composiciones farmaceuticas y metodos relacionados con ellos. | |
| AR100437A1 (es) | Composiciones para el cuidado bucal | |
| EA201171399A1 (ru) | Способ и композиция для улучшения всасывания лекарственных средств | |
| WO2015038552A3 (en) | Aspirin formulation for increased efficacy | |
| JP2019104727A5 (enExample) | ||
| JP2018532806A5 (enExample) | ||
| JP2019142974A5 (enExample) | ||
| EA201992382A3 (ru) | Пероральная таблетированная фармацевтическая композиция двойного применения на основе сульфатных солей и способы ее применения | |
| RU2016129069A (ru) | Композиции и способы ингибирования воспаления и заболеваний с применением антимикробного соединения на основе альгиновой кислоты | |
| WO2018234871A3 (en) | COMPOSITIONS FOR DRUG DELIVERY AND METHODS OF USE | |
| BR112017014016A2 (pt) | método de redução da pressão intraocular, e, composição farmacêutica. | |
| UA122336C2 (uk) | Бісамідна похідна дикарбонової кислоти як засіб, що стимулює регенерацію тканин і відновлення знижених функцій тканин | |
| JP2019520377A5 (enExample) | ||
| HRP20180178T1 (hr) | Pripravci ketorolaka, namijenjeni zacjeljivanju rane na rožnici |