JP2014218522A5 - - Google Patents
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- Publication number
- JP2014218522A5 JP2014218522A5 JP2014167069A JP2014167069A JP2014218522A5 JP 2014218522 A5 JP2014218522 A5 JP 2014218522A5 JP 2014167069 A JP2014167069 A JP 2014167069A JP 2014167069 A JP2014167069 A JP 2014167069A JP 2014218522 A5 JP2014218522 A5 JP 2014218522A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- pharmaceutical composition
- composition according
- daily dose
- loxoprofen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000003839 salts Chemical class 0.000 claims 15
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 claims 6
- 229960002373 loxoprofen Drugs 0.000 claims 6
- BAZQYVYVKYOAGO-UHFFFAOYSA-M loxoprofen sodium hydrate Chemical compound O.O.[Na+].C1=CC(C(C([O-])=O)C)=CC=C1CC1C(=O)CCC1 BAZQYVYVKYOAGO-UHFFFAOYSA-M 0.000 claims 5
- OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical class C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 claims 4
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 claims 4
- 229960000401 tranexamic acid Drugs 0.000 claims 4
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 claims 3
- MKXZASYAUGDDCJ-SZMVWBNQSA-N LSM-2525 Chemical compound C1CCC[C@H]2[C@@]3([H])N(C)CC[C@]21C1=CC(OC)=CC=C1C3 MKXZASYAUGDDCJ-SZMVWBNQSA-N 0.000 claims 3
- OJGDCBLYJGHCIH-UHFFFAOYSA-N bromhexine Chemical compound C1CCCCC1N(C)CC1=CC(Br)=CC(Br)=C1N OJGDCBLYJGHCIH-UHFFFAOYSA-N 0.000 claims 3
- 229960003870 bromhexine Drugs 0.000 claims 3
- 229960001948 caffeine Drugs 0.000 claims 3
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 claims 3
- SOYKEARSMXGVTM-UHFFFAOYSA-N chlorphenamine Chemical compound C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 SOYKEARSMXGVTM-UHFFFAOYSA-N 0.000 claims 3
- 229960003291 chlorphenamine Drugs 0.000 claims 3
- 229960001985 dextromethorphan Drugs 0.000 claims 3
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 150000007513 acids Chemical class 0.000 claims 2
- 208000018522 Gastrointestinal disease Diseases 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229960004126 codeine Drugs 0.000 claims 1
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 claims 1
- 229960002179 ephedrine Drugs 0.000 claims 1
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 claims 1
- -1 loxoprofen sodium anhydride Chemical class 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014167069A JP2014218522A (ja) | 2008-09-04 | 2014-08-20 | ロキソプロフェン含有医薬組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008227452 | 2008-09-04 | ||
| JP2008227452 | 2008-09-04 | ||
| JP2014167069A JP2014218522A (ja) | 2008-09-04 | 2014-08-20 | ロキソプロフェン含有医薬組成物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009204959A Division JP5835865B2 (ja) | 2008-09-04 | 2009-09-04 | ロキソプロフェン含有医薬組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016087721A Division JP6139743B2 (ja) | 2008-09-04 | 2016-04-26 | ロキソプロフェン含有医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014218522A JP2014218522A (ja) | 2014-11-20 |
| JP2014218522A5 true JP2014218522A5 (enExample) | 2015-06-25 |
Family
ID=42248184
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009204959A Active JP5835865B2 (ja) | 2008-09-04 | 2009-09-04 | ロキソプロフェン含有医薬組成物 |
| JP2014167069A Pending JP2014218522A (ja) | 2008-09-04 | 2014-08-20 | ロキソプロフェン含有医薬組成物 |
| JP2016087721A Active JP6139743B2 (ja) | 2008-09-04 | 2016-04-26 | ロキソプロフェン含有医薬組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009204959A Active JP5835865B2 (ja) | 2008-09-04 | 2009-09-04 | ロキソプロフェン含有医薬組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016087721A Active JP6139743B2 (ja) | 2008-09-04 | 2016-04-26 | ロキソプロフェン含有医薬組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (3) | JP5835865B2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5525324B2 (ja) * | 2009-04-28 | 2014-06-18 | 興和株式会社 | ロキソプロフェン含有医薬製剤 |
| JP5525323B2 (ja) * | 2009-04-28 | 2014-06-18 | 興和株式会社 | ロキソプロフェン含有医薬製剤 |
| JP5897804B2 (ja) * | 2010-02-26 | 2016-03-30 | 興和株式会社 | ロキソプロフェン含有の医薬組成物 |
| JP2011246441A (ja) * | 2010-03-31 | 2011-12-08 | Kowa Co | ロキソプロフェン又はその塩を含有する医薬組成物 |
| JP5823746B2 (ja) * | 2010-06-30 | 2015-11-25 | 興和株式会社 | 医薬組成物 |
| JP5896645B2 (ja) * | 2010-08-26 | 2016-03-30 | 興和株式会社 | ロキソプロフェン又はその塩の含有医薬製剤 |
| JP6139050B2 (ja) * | 2010-08-27 | 2017-05-31 | 興和株式会社 | 医薬 |
| JP6126780B2 (ja) * | 2010-12-13 | 2017-05-10 | 第一三共ヘルスケア株式会社 | ロキソプロフェンナトリウム及びトラネキサム酸を含有する固形製剤 |
| JP5969787B2 (ja) * | 2011-03-23 | 2016-08-17 | 第一三共ヘルスケア株式会社 | 生体内のメイラード反応抑制剤またはＡＧＥｓ生成抑制剤 |
| WO2012153827A1 (ja) * | 2011-05-11 | 2012-11-15 | 興和株式会社 | 安定な医薬組成物 |
| WO2012157752A1 (ja) * | 2011-05-18 | 2012-11-22 | 興和株式会社 | ロキソプロフェン含有の医薬組成物 |
| WO2013047869A1 (ja) * | 2011-09-29 | 2013-04-04 | 興和株式会社 | ロキソプロフェン又はその塩を含有する医薬組成物 |
| JP6018891B2 (ja) * | 2011-11-29 | 2016-11-02 | ライオン株式会社 | 解熱鎮痛組成物 |
| JP6166544B2 (ja) * | 2013-02-13 | 2017-07-19 | 第一三共ヘルスケア株式会社 | 色素沈着症の予防又は治療剤 |
| JP7229013B2 (ja) * | 2018-12-25 | 2023-02-27 | 小林製薬株式会社 | 内服用医薬組成物 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4316888A (en) * | 1980-04-15 | 1982-02-23 | Nelson Research & Development Co. | Method and composition of reducing pain |
| JP3667381B2 (ja) * | 1995-03-27 | 2005-07-06 | 株式会社資生堂 | 解熱鎮痛剤 |
| JP2004161667A (ja) * | 2002-11-13 | 2004-06-10 | Saiseido Yakuhin Kk | 生薬配合医薬組成物 |
| JP2006001920A (ja) * | 2004-05-18 | 2006-01-05 | Grelan Pharmaceut Co Ltd | 医薬製剤 |
| JP5442178B2 (ja) * | 2004-07-13 | 2014-03-12 | 第一三共株式会社 | ロキソプロフェン含有経口用組成物 |
| JP2006124380A (ja) * | 2004-09-29 | 2006-05-18 | Dai Ichi Seiyaku Co Ltd | 医薬組成物 |
| JP5101007B2 (ja) * | 2005-11-28 | 2012-12-19 | 武田薬品工業株式会社 | 安定化された医薬製剤 |
| JP2007314517A (ja) * | 2006-04-27 | 2007-12-06 | Daiichi Sankyo Healthcare Co Ltd | ロキソプロフェンを含有する鎮咳又は去痰のための医薬組成物 |
| JP2008195705A (ja) * | 2007-01-15 | 2008-08-28 | Daiichi Sankyo Healthcare Co Ltd | ロキソプロフェン含有経口用組成物 |
| JP5828609B2 (ja) * | 2008-03-31 | 2015-12-09 | 小林製薬株式会社 | 持続性解熱鎮痛消炎剤 |
| JP5542309B2 (ja) * | 2008-03-31 | 2014-07-09 | 小林製薬株式会社 | 経口医薬組成物 |
| JP5403935B2 (ja) * | 2008-03-31 | 2014-01-29 | 小林製薬株式会社 | 経口用の慢性疼痛予防または治療剤 |
-
2009
- 2009-09-04 JP JP2009204959A patent/JP5835865B2/ja active Active
-
2014
- 2014-08-20 JP JP2014167069A patent/JP2014218522A/ja active Pending
-
2016
- 2016-04-26 JP JP2016087721A patent/JP6139743B2/ja active Active
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