JP2015528110A5 - - Google Patents
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- Publication number
- JP2015528110A5 JP2015528110A5 JP2015520167A JP2015520167A JP2015528110A5 JP 2015528110 A5 JP2015528110 A5 JP 2015528110A5 JP 2015520167 A JP2015520167 A JP 2015520167A JP 2015520167 A JP2015520167 A JP 2015520167A JP 2015528110 A5 JP2015528110 A5 JP 2015528110A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- patient
- yeast
- class
- mass spectrum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010028980 Neoplasm Diseases 0.000 claims 31
- 201000011510 cancer Diseases 0.000 claims 31
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 25
- 238000001819 mass spectrum Methods 0.000 claims 22
- 239000002955 immunomodulating agent Substances 0.000 claims 18
- 238000000034 method Methods 0.000 claims 11
- 238000001228 spectrum Methods 0.000 claims 10
- 238000007781 pre-processing Methods 0.000 claims 8
- 238000012549 training Methods 0.000 claims 8
- 230000028993 immune response Effects 0.000 claims 7
- 229940124650 anti-cancer therapies Drugs 0.000 claims 6
- 238000011319 anticancer therapy Methods 0.000 claims 6
- 238000004949 mass spectrometry Methods 0.000 claims 6
- 229940124597 therapeutic agent Drugs 0.000 claims 6
- 239000008280 blood Substances 0.000 claims 5
- 210000004369 blood Anatomy 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 5
- 238000012360 testing method Methods 0.000 claims 4
- 238000011282 treatment Methods 0.000 claims 3
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 2
- SDUQYLNIPVEERB-QPPQHZFASA-N gemcitabine Chemical compound O=C1N=C(N)C=CN1[C@H]1C(F)(F)[C@H](O)[C@@H](CO)O1 SDUQYLNIPVEERB-QPPQHZFASA-N 0.000 claims 2
- 229960005277 gemcitabine Drugs 0.000 claims 2
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 229940127084 other anti-cancer agent Drugs 0.000 claims 2
- 201000002528 pancreatic cancer Diseases 0.000 claims 2
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 239000012830 cancer therapeutic Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000009169 immunotherapy Methods 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 230000003595 spectral effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261664308P | 2012-06-26 | 2012-06-26 | |
| US201261664329P | 2012-06-26 | 2012-06-26 | |
| US61/664,329 | 2012-06-26 | ||
| US61/664,308 | 2012-06-26 | ||
| PCT/US2013/032024 WO2014003853A1 (en) | 2012-06-26 | 2013-03-15 | Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015528110A JP2015528110A (ja) | 2015-09-24 |
| JP2015528110A5 true JP2015528110A5 (enExample) | 2016-05-12 |
| JP6355630B2 JP6355630B2 (ja) | 2018-07-11 |
Family
ID=48045749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015520167A Active JP6355630B2 (ja) | 2012-06-26 | 2013-03-15 | 質量スペクトルを用いて免疫応答発生治療剤で治療する癌患者を選択または除外する方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9653272B2 (enExample) |
| EP (1) | EP2864792A1 (enExample) |
| JP (1) | JP6355630B2 (enExample) |
| KR (1) | KR102103319B1 (enExample) |
| CN (1) | CN104685360B (enExample) |
| AU (1) | AU2013281221B2 (enExample) |
| CA (1) | CA2878044C (enExample) |
| HK (1) | HK1209835A1 (enExample) |
| IL (1) | IL236266A0 (enExample) |
| MX (1) | MX365418B (enExample) |
| SG (1) | SG11201408652SA (enExample) |
| TW (1) | TWI639001B (enExample) |
| WO (1) | WO2014003853A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2864792A1 (en) | 2012-06-26 | 2015-04-29 | Biodesix, Inc. | Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies |
| US11594403B1 (en) | 2014-12-03 | 2023-02-28 | Biodesix Inc. | Predictive test for prognosis of myelodysplastic syndrome patients using mass spectrometry of blood-based sample |
| US10037874B2 (en) | 2014-12-03 | 2018-07-31 | Biodesix, Inc. | Early detection of hepatocellular carcinoma in high risk populations using MALDI-TOF mass spectrometry |
| JP6647315B2 (ja) | 2015-01-09 | 2020-02-14 | イーチュービクス コーポレイション | 組み合わせ免疫療法のための方法および組成物 |
| EP3286213B1 (en) | 2015-04-20 | 2021-08-04 | Etubics Corporation | Methods and compositions for combination immunotherapy |
| WO2016175990A1 (en) * | 2015-04-30 | 2016-11-03 | Biodesix, Inc. | Bagged filtering method for selection and deselection of features for classification |
| US10974077B2 (en) | 2015-06-03 | 2021-04-13 | Montefiore Medical Center | Low intensity focused ultrasound for treating cancer and metastasis |
| CN112710723B (zh) * | 2015-07-13 | 2024-11-12 | 佰欧迪塞克斯公司 | 受益于pd-1抗体药物的肺癌患者的预测性测试和分类器开发方法 |
| JP6952056B2 (ja) * | 2016-01-22 | 2021-10-20 | オートレイシーズ, インク.Otraces, Inc. | 疾患診断を改善するシステム及び方法 |
| WO2017136139A1 (en) * | 2016-02-01 | 2017-08-10 | Biodesix, Inc. | Predictive test for melanoma patient benefit from interleukin-2 (il2) therapy |
| US11232940B2 (en) * | 2016-08-02 | 2022-01-25 | Virgin Instruments Corporation | Method and apparatus for surgical monitoring using MALDI-TOF mass spectrometry |
| EP3566054A4 (en) | 2017-01-05 | 2020-12-09 | Biodesix, Inc. | PROCESS FOR IDENTIFYING CANCER PATIENTS LIKELY TO BENEFIT FROM IMMUNOTHERAPY FOR LASTING SUSTAINABLE SUB-GROUPS OF PATIENTS WHO HAVE A BAD PROGNOSIS GENERALLY |
| EP3631839B1 (en) * | 2017-05-22 | 2024-04-03 | Beckman Coulter, Inc. | Integrated sample processing system with multiple detection capability |
| WO2019094802A1 (en) | 2017-11-09 | 2019-05-16 | Montefiore Medical Center | Low energy immune priming for treating cancer and metastasis |
| WO2019118873A2 (en) | 2017-12-15 | 2019-06-20 | Iovance Biotherapeutics, Inc. | Systems and methods for determining the beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof and beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof |
| EP3773691A4 (en) | 2018-03-29 | 2022-06-15 | Biodesix, Inc. | Apparatus and method for identification of primary immune resistance in cancer patients |
| WO2020167471A1 (en) * | 2019-02-15 | 2020-08-20 | Biodesix, Inc. | Predictive test for identification of early stage nsclc patients at high risk of recurrence after surgery |
| CN110674947B (zh) * | 2019-09-02 | 2021-02-19 | 三峡大学 | 基于Stacking集成框架的光谱特征变量选择与优化方法 |
| EP4046183A1 (en) * | 2019-10-17 | 2022-08-24 | DH Technologies Development Pte. Ltd. | Threshold-based ida exclusion list |
| CN112164448B (zh) * | 2020-09-25 | 2021-06-22 | 上海市胸科医院 | 免疫治疗疗效预测模型训练方法、预测系统及方法和介质 |
| CN116685259A (zh) * | 2020-10-19 | 2023-09-01 | 本-古里安大学B.G.内盖夫技术和应用公司 | 尿细菌对抗生素的敏感性的快速直接鉴定和确定 |
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| FR2486400B1 (fr) | 1980-07-09 | 1986-05-30 | Univablot | Medicaments a base de levures ou de leurs extraits insolubles |
| NZ199722A (en) | 1981-02-25 | 1985-12-13 | Genentech Inc | Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain |
| US4514506A (en) | 1982-02-23 | 1985-04-30 | The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services | Method for the identification and purification of human lung tumor-associated antigens (hLTAA) and clinical detection and determination of these antigens |
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| EP2864792A1 (en) | 2012-06-26 | 2015-04-29 | Biodesix, Inc. | Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies |
| CH715107B1 (fr) | 2018-06-18 | 2021-12-30 | Montres Breguet Sa | Mécanisme de réglage pour mécanisme d'affichage d'horlogerie à rouleau. |
-
2013
- 2013-03-15 EP EP13714124.8A patent/EP2864792A1/en not_active Withdrawn
- 2013-03-15 CA CA2878044A patent/CA2878044C/en active Active
- 2013-03-15 AU AU2013281221A patent/AU2013281221B2/en active Active
- 2013-03-15 WO PCT/US2013/032024 patent/WO2014003853A1/en not_active Ceased
- 2013-03-15 US US13/835,909 patent/US9653272B2/en active Active
- 2013-03-15 MX MX2014015665A patent/MX365418B/es active IP Right Grant
- 2013-03-15 KR KR1020157001998A patent/KR102103319B1/ko active Active
- 2013-03-15 CN CN201380043182.4A patent/CN104685360B/zh active Active
- 2013-03-15 SG SG11201408652SA patent/SG11201408652SA/en unknown
- 2013-03-15 JP JP2015520167A patent/JP6355630B2/ja active Active
- 2013-03-15 HK HK15110515.8A patent/HK1209835A1/xx unknown
- 2013-05-03 TW TW102115975A patent/TWI639001B/zh active
-
2014
- 2014-12-15 IL IL236266A patent/IL236266A0/en unknown
-
2017
- 2017-05-02 US US15/584,275 patent/US10593529B2/en active Active
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