JP2015527355A5 - - Google Patents

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JP2015527355A5
JP2015527355A5 JP2015527965A JP2015527965A JP2015527355A5 JP 2015527355 A5 JP2015527355 A5 JP 2015527355A5 JP 2015527965 A JP2015527965 A JP 2015527965A JP 2015527965 A JP2015527965 A JP 2015527965A JP 2015527355 A5 JP2015527355 A5 JP 2015527355A5
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JP
Japan
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optionally substituted
compound
group
pharmaceutical composition
disease
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JP2015527965A
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English (en)
Japanese (ja)
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JP2015527355A (ja
JP6392754B2 (ja
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Priority claimed from PCT/GB2013/052192 external-priority patent/WO2014029983A1/en
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Publication of JP2015527355A5 publication Critical patent/JP2015527355A5/ja
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JP2015527965A 2012-08-21 2013-08-20 体液貯留又は塩過負荷に関係する疾患及び消化管疾患の治療におけるnhe仲介の逆輸送を阻害するための化合物並びに方法 Active JP6392754B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261691635P 2012-08-21 2012-08-21
US61/691,635 2012-08-21
PCT/GB2013/052192 WO2014029983A1 (en) 2012-08-21 2013-08-20 Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders

Publications (3)

Publication Number Publication Date
JP2015527355A JP2015527355A (ja) 2015-09-17
JP2015527355A5 true JP2015527355A5 (OSRAM) 2016-10-20
JP6392754B2 JP6392754B2 (ja) 2018-09-19

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ID=49083709

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015527965A Active JP6392754B2 (ja) 2012-08-21 2013-08-20 体液貯留又は塩過負荷に関係する疾患及び消化管疾患の治療におけるnhe仲介の逆輸送を阻害するための化合物並びに方法

Country Status (12)

Country Link
US (1) US20150336892A1 (OSRAM)
EP (1) EP2887964B1 (OSRAM)
JP (1) JP6392754B2 (OSRAM)
KR (1) KR102138390B1 (OSRAM)
CN (1) CN104902930A (OSRAM)
AU (3) AU2013304812B2 (OSRAM)
BR (1) BR112015003527A2 (OSRAM)
CA (1) CA2880338A1 (OSRAM)
HK (1) HK1211469A1 (OSRAM)
MX (1) MX366293B (OSRAM)
RU (1) RU2015107019A (OSRAM)
WO (1) WO2014029983A1 (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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WO2012006474A2 (en) 2010-07-07 2012-01-12 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
EP2590510B1 (en) 2010-07-07 2016-09-28 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
WO2012054110A2 (en) 2010-07-07 2012-04-26 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
ES2547890T3 (es) 2010-07-07 2015-10-09 Ardelyx, Inc. Compuestos y métodos para inhibir el transporte de fosfato
EP3552630A1 (en) 2013-04-12 2019-10-16 Ardelyx, Inc. Nhe3-binding compounds for inhibiting phosphate transport
EP3811977B1 (en) 2014-05-01 2025-12-03 Ionis Pharmaceuticals, Inc. Method for synthesis of reactive conjugate clusters
ME03311B (me) 2014-07-25 2019-10-20 Taisho Pharmaceutical Co Ltd Fenil teтrahidroizokvinolinsko jedinjenje supsтituisano heteroarilom
BR112019013963A2 (pt) 2017-01-09 2020-04-28 Ardelyx Inc inibidores de antiporte mediado por nhe
US11242337B2 (en) * 2017-01-09 2022-02-08 Ardelyx, Inc. Compounds useful for treating gastrointestinal tract disorders
MA49761A (fr) 2017-08-04 2020-06-10 Ardelyx Inc Dérivés d'acide glycyrrhétinique de traitement de l'hyperkaliémie
AU2018312836B2 (en) 2017-08-07 2022-12-08 Joint Stock Company "Biocad" Novel heterocyclic compounds as CDK8/19 inhibitors
PH12021551892A1 (en) 2019-02-07 2022-08-01 Ardelyx Inc Glycyrrhetinic acid derivatives for use in treating hyperkalemia

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