JP2015525575A5 - - Google Patents
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- JP2015525575A5 JP2015525575A5 JP2015526715A JP2015526715A JP2015525575A5 JP 2015525575 A5 JP2015525575 A5 JP 2015525575A5 JP 2015526715 A JP2015526715 A JP 2015526715A JP 2015526715 A JP2015526715 A JP 2015526715A JP 2015525575 A5 JP2015525575 A5 JP 2015525575A5
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- Prior art keywords
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- nucleic acid
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- 238000000034 method Methods 0.000 claims description 107
- 239000000203 mixture Substances 0.000 claims description 29
- 108020004707 nucleic acids Proteins 0.000 claims description 18
- 102000039446 nucleic acids Human genes 0.000 claims description 18
- 150000007523 nucleic acids Chemical class 0.000 claims description 18
- 208000031212 Autoimmune polyendocrinopathy Diseases 0.000 claims description 15
- 235000019395 ammonium persulphate Nutrition 0.000 claims description 14
- 238000000261 appearance potential spectroscopy Methods 0.000 claims description 11
- 230000003321 amplification Effects 0.000 claims description 7
- 230000015572 biosynthetic process Effects 0.000 claims description 7
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 7
- 238000003786 synthesis reaction Methods 0.000 claims description 7
- 238000002955 isolation Methods 0.000 claims description 4
- 238000000926 separation method Methods 0.000 claims description 4
- 102000004169 proteins and genes Human genes 0.000 claims description 3
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 238000012163 sequencing technique Methods 0.000 claims description 3
- 230000001413 cellular effect Effects 0.000 claims description 2
- 108020004999 messenger RNA Proteins 0.000 claims description 2
- 238000001311 chemical methods and process Methods 0.000 claims 1
- 239000000523 sample Substances 0.000 description 8
- 239000000126 substance Substances 0.000 description 6
- 229920000642 polymer Polymers 0.000 description 5
- 230000001419 dependent effect Effects 0.000 description 3
- 238000002372 labelling Methods 0.000 description 3
- 108091034117 Oligonucleotide Proteins 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 239000013589 supplement Substances 0.000 description 2
- 102000015636 Oligopeptides Human genes 0.000 description 1
- 108010038807 Oligopeptides Proteins 0.000 description 1
- 108091093037 Peptide nucleic acid Proteins 0.000 description 1
- 102000007982 Phosphoproteins Human genes 0.000 description 1
- 108010089430 Phosphoproteins Proteins 0.000 description 1
- -1 antibodies Proteins 0.000 description 1
- 150000002016 disaccharides Chemical class 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 150000004043 trisaccharides Chemical class 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261681121P | 2012-08-08 | 2012-08-08 | |
| US61/681,121 | 2012-08-08 | ||
| PCT/US2013/054190 WO2014026032A2 (en) | 2012-08-08 | 2013-08-08 | Increasing dynamic range for identifying multiple epitopes in cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017248778A Division JP2018046856A (ja) | 2012-08-08 | 2017-12-26 | 細胞中の複数のエピトープを同定するためのダイナミックレンジを高めること |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015525575A JP2015525575A (ja) | 2015-09-07 |
| JP2015525575A5 true JP2015525575A5 (enExample) | 2016-09-29 |
| JP6525872B2 JP6525872B2 (ja) | 2019-06-05 |
Family
ID=50068714
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015526715A Active JP6525872B2 (ja) | 2012-08-08 | 2013-08-08 | 細胞中の複数のエピトープを同定するためのダイナミックレンジを高めること |
| JP2017248778A Pending JP2018046856A (ja) | 2012-08-08 | 2017-12-26 | 細胞中の複数のエピトープを同定するためのダイナミックレンジを高めること |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017248778A Pending JP2018046856A (ja) | 2012-08-08 | 2017-12-26 | 細胞中の複数のエピトープを同定するためのダイナミックレンジを高めること |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US10174310B2 (enExample) |
| EP (3) | EP3578669B1 (enExample) |
| JP (2) | JP6525872B2 (enExample) |
| CN (1) | CN105264088B (enExample) |
| WO (1) | WO2014026032A2 (enExample) |
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- 2013-08-08 CN CN201380052460.2A patent/CN105264088B/zh active Active
- 2013-08-08 US US14/420,345 patent/US10174310B2/en active Active
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