CN105264088B - 提高鉴定细胞中的多个表位的动态范围 - Google Patents

提高鉴定细胞中的多个表位的动态范围 Download PDF

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CN105264088B
CN105264088B CN201380052460.2A CN201380052460A CN105264088B CN 105264088 B CN105264088 B CN 105264088B CN 201380052460 A CN201380052460 A CN 201380052460A CN 105264088 B CN105264088 B CN 105264088B
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CN105264088A (zh
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盖瑞·P·诺兰
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F Hoffmann La Roche AG
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

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CN201380052460.2A 2012-08-08 2013-08-08 提高鉴定细胞中的多个表位的动态范围 Active CN105264088B (zh)

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US201261681121P 2012-08-08 2012-08-08
US61/681,121 2012-08-08
PCT/US2013/054190 WO2014026032A2 (en) 2012-08-08 2013-08-08 Increasing dynamic range for identifying multiple epitopes in cells

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