JP2015524652A5 - - Google Patents
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- Publication number
- JP2015524652A5 JP2015524652A5 JP2015501989A JP2015501989A JP2015524652A5 JP 2015524652 A5 JP2015524652 A5 JP 2015524652A5 JP 2015501989 A JP2015501989 A JP 2015501989A JP 2015501989 A JP2015501989 A JP 2015501989A JP 2015524652 A5 JP2015524652 A5 JP 2015524652A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- amino acid
- cells
- apc
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 26
- 125000003275 alpha amino acid group Chemical group 0.000 claims 11
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 11
- 239000012634 fragment Substances 0.000 claims 9
- 210000000447 Th1 cell Anatomy 0.000 claims 7
- 102000040430 polynucleotide Human genes 0.000 claims 6
- 108091033319 polynucleotide Proteins 0.000 claims 6
- 239000002157 polynucleotide Substances 0.000 claims 6
- 210000001744 T-lymphocyte Anatomy 0.000 claims 5
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 5
- 230000001939 inductive effect Effects 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 108010027412 Histocompatibility Antigens Class II Proteins 0.000 claims 4
- 102000018713 Histocompatibility Antigens Class II Human genes 0.000 claims 4
- 108091008874 T cell receptors Proteins 0.000 claims 4
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 102000043131 MHC class II family Human genes 0.000 claims 3
- 108091054438 MHC class II family Proteins 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 3
- 238000000338 in vitro Methods 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 108010063970 HLA-DR15 antigen Proteins 0.000 claims 2
- 108010086066 HLA-DR8 antigen Proteins 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 108010062347 HLA-DQ Antigens Proteins 0.000 claims 1
- 101001065550 Homo sapiens Lymphocyte antigen 6K Proteins 0.000 claims 1
- 102100032129 Lymphocyte antigen 6K Human genes 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 230000002980 postoperative effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261669995P | 2012-07-10 | 2012-07-10 | |
| US61/669,995 | 2012-07-10 | ||
| PCT/JP2013/004249 WO2014010232A1 (en) | 2012-07-10 | 2013-07-09 | Ly6k epitope peptides for th1 cells and vaccines containing the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015524652A JP2015524652A (ja) | 2015-08-27 |
| JP2015524652A5 true JP2015524652A5 (enExample) | 2016-06-02 |
| JP6255594B2 JP6255594B2 (ja) | 2018-01-10 |
Family
ID=49915713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015501989A Expired - Fee Related JP6255594B2 (ja) | 2012-07-10 | 2013-07-09 | Ｔｈ１細胞のＬＹ６Ｋエピトープペプチドおよびこれを含有するワクチン |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9644010B2 (enExample) |
| EP (1) | EP2872531A4 (enExample) |
| JP (1) | JP6255594B2 (enExample) |
| TW (2) | TWI636991B (enExample) |
| WO (1) | WO2014010232A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL250235B (en) * | 2014-08-04 | 2022-07-01 | Oncotherapy Science Inc | A peptide derived from urlc10 and a component containing it |
| BR112018006894A2 (pt) * | 2015-10-08 | 2018-10-16 | Oncotherapy Science, Inc. | peptídeo derivado de mphosph1 e vacina que inclui o mesmo |
| JP2019535270A (ja) * | 2016-11-18 | 2019-12-12 | オンコセラピー・サイエンス株式会社 | Ｔｈ１細胞のためのＤＥＰＤＣ１エピトープペプチドおよびこれを含有するワクチン |
| WO2018092755A1 (en) * | 2016-11-18 | 2018-05-24 | Oncotherapy Science, Inc. | Mphosph1 epitope peptides for th1 cells and vaccines containing the same |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
| EP0239102A3 (en) | 1986-03-28 | 1989-07-12 | Tsuji, Kimiyoshi | Process for the formation of human-human hybridoma |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| DE69133476T2 (de) | 1990-08-29 | 2006-01-05 | GenPharm International, Inc., Palo Alto | Transgene Mäuse fähig zur Produktion heterologer Antikörper |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5679647A (en) | 1993-08-26 | 1997-10-21 | The Regents Of The University Of California | Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides |
| US5804566A (en) | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
| US5739118A (en) | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
| US5736524A (en) | 1994-11-14 | 1998-04-07 | Merck & Co.,. Inc. | Polynucleotide tuberculosis vaccine |
| US5922687A (en) | 1995-05-04 | 1999-07-13 | Board Of Trustees Of The Leland Stanford Junior University | Intracellular delivery of nucleic acids using pressure |
| CA2262006A1 (en) | 1996-07-26 | 1998-02-05 | Sloan-Kettering Institute For Cancer Research | Method and reagents for genetic immunization |
| US7041297B1 (en) | 1998-06-25 | 2006-05-09 | Sumitomo Pharmaceuticals Company | Tumor antigen peptides originating in cyclophilin B |
| TW200413725A (en) | 2002-09-30 | 2004-08-01 | Oncotherapy Science Inc | Method for diagnosing non-small cell lung cancers |
| US20060024692A1 (en) | 2002-09-30 | 2006-02-02 | Oncotherapy Science, Inc. | Method for diagnosing non-small cell lung cancers |
| US7998695B2 (en) | 2005-02-10 | 2011-08-16 | Oncotherapy Science, Inc. | Method of diagnosing bladder cancer |
| PT2325306E (pt) | 2005-02-25 | 2014-04-29 | Oncotherapy Science Inc | Vacinas peptídicas para cancros do pulmão que expressam polipéptidos ttk, urlc10 ou koc1 |
| TWI615403B (zh) * | 2007-02-21 | 2018-02-21 | 腫瘤療法 科學股份有限公司 | 表現腫瘤相關抗原之癌症的胜肽疫苗 |
| WO2009016691A1 (en) | 2007-07-30 | 2009-02-05 | Oncotherapy Science, Inc. | Cancer associated gene ly6k |
| TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
| TWI580431B (zh) | 2008-08-19 | 2017-05-01 | 腫瘤療法 科學股份有限公司 | Ｈｉｇ２與ｕｒｌｃ１０抗原決定位胜肽以及含此胜肽之疫苗 |
-
2013
- 2013-07-09 WO PCT/JP2013/004249 patent/WO2014010232A1/en not_active Ceased
- 2013-07-09 JP JP2015501989A patent/JP6255594B2/ja not_active Expired - Fee Related
- 2013-07-09 EP EP13817006.3A patent/EP2872531A4/en not_active Withdrawn
- 2013-07-09 US US14/413,416 patent/US9644010B2/en not_active Expired - Fee Related
- 2013-07-10 TW TW106134169A patent/TWI636991B/zh not_active IP Right Cessation
- 2013-07-10 TW TW102124657A patent/TWI609880B/zh not_active IP Right Cessation