JP2015523986A - ラキニモドを使用する眼炎症性疾患の治療 - Google Patents

ラキニモドを使用する眼炎症性疾患の治療 Download PDF

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Publication number
JP2015523986A
JP2015523986A JP2015516113A JP2015516113A JP2015523986A JP 2015523986 A JP2015523986 A JP 2015523986A JP 2015516113 A JP2015516113 A JP 2015516113A JP 2015516113 A JP2015516113 A JP 2015516113A JP 2015523986 A JP2015523986 A JP 2015523986A
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Prior art keywords
laquinimod
pharmaceutically acceptable
acceptable salt
subject
effective amount
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Pending
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JP2015516113A
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English (en)
Japanese (ja)
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JP2015523986A5 (cg-RX-API-DMAC7.html
Inventor
カイェ、ジョエル
ハラーク、フセイン
タルシック、ノラ
Original Assignee
テバ ファーマシューティカル インダストリーズ リミティド
テバ ファーマシューティカル インダストリーズ リミティド
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Publication of JP2015523986A publication Critical patent/JP2015523986A/ja
Publication of JP2015523986A5 publication Critical patent/JP2015523986A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2015516113A 2012-06-05 2013-06-04 ラキニモドを使用する眼炎症性疾患の治療 Pending JP2015523986A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261655526P 2012-06-05 2012-06-05
US61/655,526 2012-06-05
PCT/US2013/044058 WO2013184650A2 (en) 2012-06-05 2013-06-04 Treatment of ocular inflammatory diseases using laquinimod

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017158674A Division JP2018024677A (ja) 2012-06-05 2017-08-21 ラキニモドを使用する眼炎症性疾患の治療

Publications (2)

Publication Number Publication Date
JP2015523986A true JP2015523986A (ja) 2015-08-20
JP2015523986A5 JP2015523986A5 (cg-RX-API-DMAC7.html) 2016-07-21

Family

ID=49671002

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015516113A Pending JP2015523986A (ja) 2012-06-05 2013-06-04 ラキニモドを使用する眼炎症性疾患の治療
JP2017158674A Withdrawn JP2018024677A (ja) 2012-06-05 2017-08-21 ラキニモドを使用する眼炎症性疾患の治療

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017158674A Withdrawn JP2018024677A (ja) 2012-06-05 2017-08-21 ラキニモドを使用する眼炎症性疾患の治療

Country Status (10)

Country Link
US (6) US20130324574A1 (cg-RX-API-DMAC7.html)
EP (1) EP2854767A4 (cg-RX-API-DMAC7.html)
JP (2) JP2015523986A (cg-RX-API-DMAC7.html)
AR (1) AR092842A1 (cg-RX-API-DMAC7.html)
CA (1) CA2874767A1 (cg-RX-API-DMAC7.html)
IL (1) IL235874A0 (cg-RX-API-DMAC7.html)
RU (1) RU2014151992A (cg-RX-API-DMAC7.html)
TW (1) TW201400117A (cg-RX-API-DMAC7.html)
UY (1) UY34843A (cg-RX-API-DMAC7.html)
WO (1) WO2013184650A2 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023509336A (ja) * 2019-12-19 2023-03-08 アクティブ バイオテック エービー 過剰血管新生に関連する眼疾患を治療する化合物

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Publication number Priority date Publication date Assignee Title
MX2014009373A (es) 2012-02-03 2014-08-27 Teva Pharma Uso de laquinimod para tratar pacientes con enfermedad de crohn que fallaron en la terapia de anti-tnfa de primera linea.
TW201410244A (zh) 2012-08-13 2014-03-16 Teva Pharma 用於治療ｇａｂａ媒介之疾病之拉喹莫德（ｌａｑｕｉｎｉｍｏｄ）
US20150141458A1 (en) * 2013-11-15 2015-05-21 Teva Pharmaceutical Industries, Ltd. Treatment of Glaucoma Using Laquinimod
WO2015168103A1 (en) 2014-04-29 2015-11-05 Teva Pharmaceutical Industries Ltd. Laquinimod for the treatment of relapsing-remitting multiple sclerosis (rrms) patients with a high disability status
US20240180819A1 (en) * 2021-04-01 2024-06-06 Active Biotech Ab Laquinimod formulation for ocular use

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023509336A (ja) * 2019-12-19 2023-03-08 アクティブ バイオテック エービー 過剰血管新生に関連する眼疾患を治療する化合物
JP7730816B2 (ja) 2019-12-19 2025-08-28 アクティブ バイオテック エービー 過剰血管新生に関連する眼疾患を治療する化合物

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Publication number Publication date
UY34843A (es) 2013-12-31
US20170231971A1 (en) 2017-08-17
WO2013184650A2 (en) 2013-12-12
US20130324574A1 (en) 2013-12-05
AR092842A1 (es) 2015-05-06
WO2013184650A3 (en) 2015-07-02
US20250134881A1 (en) 2025-05-01
RU2014151992A (ru) 2016-07-27
IL235874A0 (en) 2015-01-29
TW201400117A (zh) 2014-01-01
CA2874767A1 (en) 2013-12-12
US20180071275A1 (en) 2018-03-15
US11654140B2 (en) 2023-05-23
EP2854767A2 (en) 2015-04-08
EP2854767A4 (en) 2016-04-27
US20170333420A1 (en) 2017-11-23
JP2018024677A (ja) 2018-02-15
US20210386731A1 (en) 2021-12-16

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