JP2015522582A5 - - Google Patents
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- Publication number
- JP2015522582A5 JP2015522582A5 JP2015519247A JP2015519247A JP2015522582A5 JP 2015522582 A5 JP2015522582 A5 JP 2015522582A5 JP 2015519247 A JP2015519247 A JP 2015519247A JP 2015519247 A JP2015519247 A JP 2015519247A JP 2015522582 A5 JP2015522582 A5 JP 2015522582A5
- Authority
- JP
- Japan
- Prior art keywords
- kdel
- amino acid
- endoplasmic reticulum
- retention signal
- reticulum retention
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12382272 | 2012-07-06 | ||
| EP12382272.8 | 2012-07-06 | ||
| PCT/EP2013/064400 WO2014006225A1 (en) | 2012-07-06 | 2013-07-08 | Fluorescent fusion polypeptide, biosensor comprising said polypeptide and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015522582A JP2015522582A (ja) | 2015-08-06 |
| JP2015522582A5 true JP2015522582A5 (https=) | 2016-08-04 |
| JP6393260B2 JP6393260B2 (ja) | 2018-09-19 |
Family
ID=48803514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015519247A Active JP6393260B2 (ja) | 2012-07-06 | 2013-07-08 | 蛍光融合ポリペプチド、該ポリペプチドを含むバイオセンサー及びそれらの使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9784728B2 (https=) |
| EP (1) | EP2870475B1 (https=) |
| JP (1) | JP6393260B2 (https=) |
| CN (1) | CN104781667B (https=) |
| CA (1) | CA2878126C (https=) |
| DK (1) | DK2870475T3 (https=) |
| ES (1) | ES2645431T3 (https=) |
| IN (1) | IN2014MN02585A (https=) |
| WO (1) | WO2014006225A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2645431T3 (es) | 2012-07-06 | 2017-12-05 | Innovative Technologies In Biological Systems S.L. | Polipéptido de fusión fluorescente, biosensor que comprende dicho polipéptido y usos de los mismos |
| US9784726B2 (en) | 2013-01-08 | 2017-10-10 | Atrogi Ab | Screening method, a kit, a method of treatment and a compound for use in a method of treatment |
| ES2952996T3 (es) * | 2017-02-06 | 2023-11-07 | Innovative Tech In Biological Systems Sl | Polipéptido de fusión fluorescente capaz de detectar la fosforilación de receptores de membrana celular por GRK (cinasas receptoras de proteína G) y/o tirosina cinasas receptoras (RTK) |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH089640B2 (ja) * | 1994-05-19 | 1996-01-31 | 佑 本庶 | ヒト・インターロイキン−２受容体 |
| US6197928B1 (en) | 1997-03-14 | 2001-03-06 | The Regents Of The University Of California | Fluorescent protein sensors for detection of analytes |
| US7192932B1 (en) * | 1997-04-29 | 2007-03-20 | Lauras As | Use of immunomodulating agents |
| WO1999060113A1 (en) * | 1998-05-20 | 1999-11-25 | Chugai Seiyaku Kabushiki Kaisha | Novel method for isolating gene |
| AU1912000A (en) * | 1998-11-12 | 2000-05-29 | Beth Israel Deaconess Medical Center | Stimulation of angiogenesis via syndecan-4 cytoplasmic domain signaling pathway |
| US7060793B2 (en) * | 1999-05-21 | 2006-06-13 | The Regents Of The University Of California | Circularly permuted fluorescent protein indicators |
| US20070037165A1 (en) * | 2000-09-08 | 2007-02-15 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| US7125660B2 (en) * | 2000-09-13 | 2006-10-24 | Archemix Corp. | Nucleic acid sensor molecules and methods of using same |
| EP1499885B1 (en) * | 2001-08-01 | 2009-10-21 | Cellomics, Inc. | Novel fusion proteins and assays for molecular binding |
| CA2497254A1 (en) * | 2002-09-06 | 2004-03-18 | Forschungsverbund Berlin E. V. | Akap18 delta, a novel splicing variant of a protein kinase a anchor protein and the use of the same |
| JP4214206B2 (ja) * | 2002-12-10 | 2009-01-28 | 独立行政法人理化学研究所 | Ｆｒｅｔを利用した蛍光指示薬 |
| US7488583B2 (en) * | 2003-09-25 | 2009-02-10 | Odyssey Thera, Inc. | Fragment complementation assays for G-protein-coupled receptors and their signaling pathways |
| GB0411586D0 (en) * | 2004-05-24 | 2004-06-23 | Univ The Glasgow | Fluorescent protein |
| WO2006017751A2 (en) * | 2004-08-02 | 2006-02-16 | Cellumen, Inc. | Methods for the detection of molecular interactions within cells |
| EP1997885A1 (en) * | 2007-05-29 | 2008-12-03 | AXXAM S.p.A. | Fluorescent proteins and methods of use thereof |
| WO2009026941A1 (en) * | 2007-08-24 | 2009-03-05 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Genetically encoded calcium sensors comprising the c-terminal lobe of troponin c and a fluorescence tag |
| JP2009153399A (ja) * | 2007-12-25 | 2009-07-16 | National Institute Of Advanced Industrial & Technology | 一分子型リアルタイム生物発光イメージングプローブ |
| JP5798489B2 (ja) * | 2009-01-12 | 2015-10-21 | ストロ バイオファーマ， インコーポレイテッド | インビトロタンパク質合成システムを用いて非天然アミノ酸をタンパク質に選択的に導入するためのモノチャージシステム |
| CA2772572A1 (en) * | 2009-08-31 | 2011-03-03 | Ibc Pharmaceuticals, Inc. | Bispecific immunocytokine dock-and-lock (dnl) complexes and therapeutic use thereof |
| ES2645431T3 (es) | 2012-07-06 | 2017-12-05 | Innovative Technologies In Biological Systems S.L. | Polipéptido de fusión fluorescente, biosensor que comprende dicho polipéptido y usos de los mismos |
-
2013
- 2013-07-08 ES ES13739169.4T patent/ES2645431T3/es active Active
- 2013-07-08 US US14/412,513 patent/US9784728B2/en active Active
- 2013-07-08 CN CN201380045944.4A patent/CN104781667B/zh active Active
- 2013-07-08 DK DK13739169.4T patent/DK2870475T3/en active
- 2013-07-08 IN IN2585MUN2014 patent/IN2014MN02585A/en unknown
- 2013-07-08 JP JP2015519247A patent/JP6393260B2/ja active Active
- 2013-07-08 EP EP13739169.4A patent/EP2870475B1/en active Active
- 2013-07-08 WO PCT/EP2013/064400 patent/WO2014006225A1/en not_active Ceased
- 2013-07-08 CA CA2878126A patent/CA2878126C/en active Active
-
2017
- 2017-09-19 US US15/708,971 patent/US10877025B2/en active Active
- 2017-09-19 US US15/709,000 patent/US10883981B2/en active Active
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