JP2015520759A5 - - Google Patents
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- Publication number
- JP2015520759A5 JP2015520759A5 JP2015512967A JP2015512967A JP2015520759A5 JP 2015520759 A5 JP2015520759 A5 JP 2015520759A5 JP 2015512967 A JP2015512967 A JP 2015512967A JP 2015512967 A JP2015512967 A JP 2015512967A JP 2015520759 A5 JP2015520759 A5 JP 2015520759A5
- Authority
- JP
- Japan
- Prior art keywords
- metformin
- composition
- metazolamide
- combination
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FLOSMHQXBMRNHR-DAXSKMNVSA-N methazolamide Chemical compound CC(=O)\N=C1/SC(S(N)(=O)=O)=NN1C FLOSMHQXBMRNHR-DAXSKMNVSA-N 0.000 claims description 27
- 229960004083 methazolamide Drugs 0.000 claims description 26
- 239000000203 mixture Substances 0.000 claims description 21
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical group CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 claims description 20
- 229960003105 metformin Drugs 0.000 claims description 19
- 229940125708 antidiabetic agent Drugs 0.000 claims description 17
- 239000003472 antidiabetic agent Substances 0.000 claims description 17
- 230000004580 weight loss Effects 0.000 claims description 7
- 239000000654 additive Substances 0.000 claims description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 2
- 239000008280 blood Substances 0.000 claims description 2
- 210000004369 blood Anatomy 0.000 claims description 2
- 230000037396 body weight Effects 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims description 2
- 239000008103 glucose Substances 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 229960004329 metformin hydrochloride Drugs 0.000 claims 1
- OETHQSJEHLVLGH-UHFFFAOYSA-N metformin hydrochloride Chemical compound Cl.CN(C)C(=N)N=C(N)N OETHQSJEHLVLGH-UHFFFAOYSA-N 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 208000016261 weight loss Diseases 0.000 claims 1
- 238000000034 method Methods 0.000 description 10
- 230000000694 effects Effects 0.000 description 7
- 230000000977 initiatory effect Effects 0.000 description 2
- 239000000902 placebo Substances 0.000 description 2
- 229940068196 placebo Drugs 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000021045 dietary change Nutrition 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261651335P | 2012-05-24 | 2012-05-24 | |
| US61/651,335 | 2012-05-24 | ||
| PCT/AU2013/000259 WO2013173858A1 (en) | 2012-05-24 | 2013-03-15 | A method of weight reduction |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015520759A JP2015520759A (ja) | 2015-07-23 |
| JP2015520759A5 true JP2015520759A5 (https=) | 2016-05-12 |
| JP6438389B2 JP6438389B2 (ja) | 2018-12-12 |
Family
ID=49622926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015512967A Expired - Fee Related JP6438389B2 (ja) | 2012-05-24 | 2013-03-15 | 減量法 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20150174108A1 (https=) |
| EP (1) | EP2854806A4 (https=) |
| JP (1) | JP6438389B2 (https=) |
| KR (1) | KR20150023404A (https=) |
| CN (1) | CN104582701B (https=) |
| AU (1) | AU2013202981B2 (https=) |
| BR (1) | BR112014029302A2 (https=) |
| CA (1) | CA2874512A1 (https=) |
| CO (1) | CO7160083A2 (https=) |
| HK (1) | HK1209041A1 (https=) |
| MX (1) | MX2014014316A (https=) |
| NZ (1) | NZ702666A (https=) |
| RU (1) | RU2664442C2 (https=) |
| SG (1) | SG11201407786XA (https=) |
| WO (1) | WO2013173858A1 (https=) |
| ZA (1) | ZA201408703B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5301465B2 (ja) | 2007-01-25 | 2013-09-25 | バーバ・ファーマシューティカルズ・リミテッド | インスリン抵抗性改善薬および治療方法 |
| US20150150855A1 (en) * | 2012-05-24 | 2015-06-04 | Verva Pharmaceuticals Ltd | Method of improving liver function |
| US10039752B2 (en) * | 2016-07-21 | 2018-08-07 | Cipla Limited | Methazolamide for the treatment of cancer |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2783241A (en) * | 1957-02-26 | S-acylimino-x-substituted-az-i | ||
| JP2000080047A (ja) * | 1998-06-30 | 2000-03-21 | Takeda Chem Ind Ltd | 医 薬 |
| US6946243B2 (en) * | 2000-07-20 | 2005-09-20 | Solvay Pharmaceuticals Gmbh | Method of identifying compounds suitable for treatment and/or prophylaxis of obesity |
| AU2001280093A1 (en) * | 2000-08-11 | 2002-02-25 | Einar Stefansson | Method for the prevention and treatment of retinopathy |
| MXPA05009933A (es) * | 2003-03-18 | 2005-11-04 | Novartis Ag | Composiciones que comprenden acidos grasos y aminoacidos. |
| HUE034290T2 (en) * | 2003-04-29 | 2018-02-28 | Orexigen Therapeutics Inc | Preparations containing opioid antagonist and bupropion to affect weight loss |
| TW200526678A (en) | 2003-08-01 | 2005-08-16 | Janssen Pharmaceutica Nv | Substituted indole-O-glucosides |
| WO2007114948A2 (en) * | 2006-04-04 | 2007-10-11 | The Brigham And Women's Hospital, Inc. | Methods and compositions for inhibiting cell death |
| JP5301465B2 (ja) * | 2007-01-25 | 2013-09-25 | バーバ・ファーマシューティカルズ・リミテッド | インスリン抵抗性改善薬および治療方法 |
| TW201105338A (en) * | 2009-07-01 | 2011-02-16 | Kissei Pharmaceutical | Medicine derived from a combination of SGLT1-inhibitor and DPP-IV inhibitor |
| DK3459558T3 (da) * | 2010-06-25 | 2020-11-02 | Univ Aston | Glycoproteiner med lipidmobiliserende egenskaber og terapeutiske anvendelser deraf |
| WO2012008549A1 (ja) * | 2010-07-15 | 2012-01-19 | 武田薬品工業株式会社 | 複素環化合物 |
| US20150150855A1 (en) * | 2012-05-24 | 2015-06-04 | Verva Pharmaceuticals Ltd | Method of improving liver function |
-
2013
- 2013-03-15 EP EP13794519.2A patent/EP2854806A4/en not_active Withdrawn
- 2013-03-15 CA CA2874512A patent/CA2874512A1/en not_active Abandoned
- 2013-03-15 KR KR20147035499A patent/KR20150023404A/ko not_active Withdrawn
- 2013-03-15 AU AU2013202981A patent/AU2013202981B2/en not_active Ceased
- 2013-03-15 JP JP2015512967A patent/JP6438389B2/ja not_active Expired - Fee Related
- 2013-03-15 WO PCT/AU2013/000259 patent/WO2013173858A1/en not_active Ceased
- 2013-03-15 RU RU2014150946A patent/RU2664442C2/ru not_active IP Right Cessation
- 2013-03-15 BR BR112014029302A patent/BR112014029302A2/pt not_active Application Discontinuation
- 2013-03-15 NZ NZ702666A patent/NZ702666A/en not_active IP Right Cessation
- 2013-03-15 SG SG11201407786XA patent/SG11201407786XA/en unknown
- 2013-03-15 MX MX2014014316A patent/MX2014014316A/es unknown
- 2013-03-15 US US14/403,495 patent/US20150174108A1/en not_active Abandoned
- 2013-03-15 CN CN201380033658.6A patent/CN104582701B/zh not_active Expired - Fee Related
- 2013-03-15 HK HK15109728.3A patent/HK1209041A1/xx unknown
-
2014
- 2014-11-26 ZA ZA2014/08703A patent/ZA201408703B/en unknown
- 2014-12-19 CO CO14279766A patent/CO7160083A2/es unknown
-
2018
- 2018-02-09 US US15/892,989 patent/US20180333398A1/en not_active Abandoned
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