JP2015520378A5 - - Google Patents
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- Publication number
- JP2015520378A5 JP2015520378A5 JP2015514216A JP2015514216A JP2015520378A5 JP 2015520378 A5 JP2015520378 A5 JP 2015520378A5 JP 2015514216 A JP2015514216 A JP 2015514216A JP 2015514216 A JP2015514216 A JP 2015514216A JP 2015520378 A5 JP2015520378 A5 JP 2015520378A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- therapy
- central memory
- sample
- cd45ro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 25
- 238000002560 therapeutic procedure Methods 0.000 claims 20
- 210000001744 T-lymphocyte Anatomy 0.000 claims 13
- 210000003071 memory t lymphocyte Anatomy 0.000 claims 13
- 239000007850 fluorescent dye Substances 0.000 claims 8
- 101001018097 Homo sapiens L-selectin Proteins 0.000 claims 6
- 102100033467 L-selectin Human genes 0.000 claims 6
- 238000002372 labelling Methods 0.000 claims 4
- 208000023275 Autoimmune disease Diseases 0.000 claims 3
- 206010012601 diabetes mellitus Diseases 0.000 claims 3
- 230000003247 decreasing effect Effects 0.000 claims 2
- 238000001943 fluorescence-activated cell sorting Methods 0.000 claims 2
- 230000000977 initiatory effect Effects 0.000 claims 2
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 238000000684 flow cytometry Methods 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261651144P | 2012-05-24 | 2012-05-24 | |
| US61/651,144 | 2012-05-24 | ||
| PCT/US2013/042627 WO2013177505A1 (en) | 2012-05-24 | 2013-05-24 | Diabetes biomarkers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018027381A Division JP6761827B2 (ja) | 2012-05-24 | 2018-02-19 | 糖尿病バイオマーカ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015520378A JP2015520378A (ja) | 2015-07-16 |
| JP2015520378A5 true JP2015520378A5 (enExample) | 2016-11-24 |
| JP6312332B2 JP6312332B2 (ja) | 2018-04-18 |
Family
ID=49621783
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015514216A Active JP6312332B2 (ja) | 2012-05-24 | 2013-05-24 | 糖尿病バイオマーカ |
| JP2018027381A Expired - Fee Related JP6761827B2 (ja) | 2012-05-24 | 2018-02-19 | 糖尿病バイオマーカ |
| JP2020150183A Pending JP2021001899A (ja) | 2012-05-24 | 2020-09-07 | 糖尿病バイオマーカ |
| JP2022175993A Pending JP2023011814A (ja) | 2012-05-24 | 2022-11-02 | 糖尿病バイオマーカ |
| JP2024120652A Pending JP2024150702A (ja) | 2012-05-24 | 2024-07-25 | 糖尿病バイオマーカ |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018027381A Expired - Fee Related JP6761827B2 (ja) | 2012-05-24 | 2018-02-19 | 糖尿病バイオマーカ |
| JP2020150183A Pending JP2021001899A (ja) | 2012-05-24 | 2020-09-07 | 糖尿病バイオマーカ |
| JP2022175993A Pending JP2023011814A (ja) | 2012-05-24 | 2022-11-02 | 糖尿病バイオマーカ |
| JP2024120652A Pending JP2024150702A (ja) | 2012-05-24 | 2024-07-25 | 糖尿病バイオマーカ |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US20130316375A1 (enExample) |
| EP (2) | EP3767295A1 (enExample) |
| JP (5) | JP6312332B2 (enExample) |
| KR (1) | KR102172285B1 (enExample) |
| CN (1) | CN104520707B (enExample) |
| AU (4) | AU2013266145A1 (enExample) |
| CA (1) | CA2874507A1 (enExample) |
| DK (1) | DK2856149T3 (enExample) |
| ES (1) | ES2810227T3 (enExample) |
| IN (1) | IN2014DN10259A (enExample) |
| MX (1) | MX357169B (enExample) |
| WO (1) | WO2013177505A1 (enExample) |
| ZA (1) | ZA201409006B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8735359B2 (en) | 2012-05-24 | 2014-05-27 | Orban Biotech Llc | Combinations of modalities for the treatment of diabetes |
| US20130316375A1 (en) * | 2012-05-24 | 2013-11-28 | Orban Biotech Llc | Diabetes biomarkers |
| CN113138279A (zh) | 2012-06-27 | 2021-07-20 | 法姆制药有限责任公司 | 融合蛋白组合物的应用 |
| GB2523399B (en) | 2014-02-25 | 2019-03-13 | Orban Tihamer | A composition comprising ten overlapping peptide fragments of the entire preproinsulin sequence |
| WO2016103390A1 (ja) * | 2014-12-25 | 2016-06-30 | 株式会社日立製作所 | インスリン分泌能分析装置、当該装置を備えるインスリン分泌能分析システム及びインスリン分泌能分析方法 |
| CN105567851A (zh) * | 2016-02-29 | 2016-05-11 | 北京泱深生物信息技术有限公司 | 一种与糖尿病相关的分子标志物 |
| EP3433612B1 (en) * | 2016-03-22 | 2024-10-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and kits of assessing status, risk or prognosis of type 1 diabetes |
| CA3184157A1 (en) | 2020-06-26 | 2021-12-30 | Phaim Pharma Ltd | Psoriasis and other autoimmune diseases antigen immune modulator (aim) therapeutic platform |
| US20240277768A1 (en) | 2021-06-17 | 2024-08-22 | Tihamer Orban | Individualized Cell Therapy Using Patient-Derived Antigen-Specific Regulatory T Cells |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1930415A4 (en) * | 2005-09-30 | 2009-05-13 | Univ Kyoto | DEVELOPMENT OF A SCREENING METHOD FOR A CONNECTABLE COMPOUND FOR IMPROVING THE PRODUCTION OF A REGULATORY T-CELL AND METHOD FOR THE PRODUCTION OF A REGULATORY T-CELL USING AN IMMUNOSUPPRESSIVE MAKROLIDANTIBIOTIC |
| US9176122B2 (en) * | 2008-03-24 | 2015-11-03 | University Of South Florida | Biomarkers for predicting response to immunosuppressive therapy |
| US20100080784A1 (en) * | 2008-09-12 | 2010-04-01 | Torrey Pines Institute For Molecular Studies | Methods for treating cachexia and lymphopenia |
| US20130316375A1 (en) * | 2012-05-24 | 2013-11-28 | Orban Biotech Llc | Diabetes biomarkers |
-
2013
- 2013-03-14 US US13/803,581 patent/US20130316375A1/en not_active Abandoned
- 2013-05-24 EP EP20184212.7A patent/EP3767295A1/en active Pending
- 2013-05-24 KR KR1020147036002A patent/KR102172285B1/ko active Active
- 2013-05-24 AU AU2013266145A patent/AU2013266145A1/en not_active Abandoned
- 2013-05-24 JP JP2015514216A patent/JP6312332B2/ja active Active
- 2013-05-24 ES ES13794110T patent/ES2810227T3/es active Active
- 2013-05-24 EP EP13794110.0A patent/EP2856149B1/en active Active
- 2013-05-24 CN CN201380027247.6A patent/CN104520707B/zh not_active Expired - Fee Related
- 2013-05-24 CA CA2874507A patent/CA2874507A1/en active Pending
- 2013-05-24 WO PCT/US2013/042627 patent/WO2013177505A1/en not_active Ceased
- 2013-05-24 MX MX2014014348A patent/MX357169B/es active IP Right Grant
- 2013-05-24 DK DK13794110.0T patent/DK2856149T3/da active
-
2014
- 2014-12-02 IN IN10259DEN2014 patent/IN2014DN10259A/en unknown
- 2014-12-08 ZA ZA2014/09006A patent/ZA201409006B/en unknown
-
2016
- 2016-06-17 US US15/185,831 patent/US20160299128A1/en not_active Abandoned
-
2018
- 2018-02-19 JP JP2018027381A patent/JP6761827B2/ja not_active Expired - Fee Related
- 2018-12-28 US US16/235,556 patent/US20190137483A1/en not_active Abandoned
-
2019
- 2019-02-07 AU AU2019200824A patent/AU2019200824B2/en not_active Ceased
-
2020
- 2020-09-07 JP JP2020150183A patent/JP2021001899A/ja active Pending
-
2021
- 2021-04-28 AU AU2021202609A patent/AU2021202609A1/en not_active Abandoned
-
2022
- 2022-11-02 JP JP2022175993A patent/JP2023011814A/ja active Pending
-
2023
- 2023-04-27 US US18/140,214 patent/US20230333094A1/en not_active Abandoned
- 2023-08-31 AU AU2023222980A patent/AU2023222980A1/en active Pending
-
2024
- 2024-07-25 JP JP2024120652A patent/JP2024150702A/ja active Pending
-
2025
- 2025-04-10 US US19/175,610 patent/US20250237643A1/en active Pending
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