JP2015516801A5 - - Google Patents
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- JP2015516801A5 JP2015516801A5 JP2014561381A JP2014561381A JP2015516801A5 JP 2015516801 A5 JP2015516801 A5 JP 2015516801A5 JP 2014561381 A JP2014561381 A JP 2014561381A JP 2014561381 A JP2014561381 A JP 2014561381A JP 2015516801 A5 JP2015516801 A5 JP 2015516801A5
- Authority
- JP
- Japan
- Prior art keywords
- binding
- seq
- cancer
- amino acid
- binding molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12159938 | 2012-03-16 | ||
| EP12159938.5 | 2012-03-16 | ||
| PCT/EP2013/054768 WO2013135588A1 (en) | 2012-03-16 | 2013-03-08 | Novel binding molecules with antitumoral activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015516801A JP2015516801A (ja) | 2015-06-18 |
| JP2015516801A5 true JP2015516801A5 (https=) | 2016-04-21 |
| JP6325463B2 JP6325463B2 (ja) | 2018-05-16 |
Family
ID=47844323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014561381A Expired - Fee Related JP6325463B2 (ja) | 2012-03-16 | 2013-03-08 | 抗腫瘍活性を有する新規結合分子 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9593314B2 (https=) |
| EP (1) | EP2825197B1 (https=) |
| JP (1) | JP6325463B2 (https=) |
| KR (1) | KR20140135251A (https=) |
| CN (1) | CN104284675B (https=) |
| AU (1) | AU2013231488B2 (https=) |
| BR (1) | BR112014022932A2 (https=) |
| CA (1) | CA2865597A1 (https=) |
| MX (1) | MX354717B (https=) |
| NZ (1) | NZ629283A (https=) |
| RU (1) | RU2627185C1 (https=) |
| WO (1) | WO2013135588A1 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013110030A2 (en) | 2012-01-19 | 2013-07-25 | Duke University | Vaccines against antigens involved in therapy resistance and methods of using same |
| EP2752426A1 (en) * | 2013-01-03 | 2014-07-09 | Covagen AG | Human serum albumin binding compounds and fusion proteins thereof |
| HRP20250551T1 (hr) | 2013-11-27 | 2025-06-20 | Zymeworks Bc Inc. | Bispecifični antigen-vezujući konstrukti koji ciljaju her2 |
| JP2017504325A (ja) * | 2014-01-14 | 2017-02-09 | インテグレイテッド バイオセラピューティクス，インコーポレイテッド | バクテリオシンの細胞壁ターゲティングドメインを用いた細菌感染部位への免疫学的機能のターゲティング方法 |
| JP2017507950A (ja) | 2014-02-27 | 2017-03-23 | リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ | レチノイン酸受容体関連オーファン受容体ガンマのアゴニストを使用する養子細胞療法及び関連治療方法 |
| US10323095B2 (en) * | 2014-03-17 | 2019-06-18 | Mitsubishi Tanabe Pharma Corporation | Antibody-fynomer conjugates |
| JP6523337B2 (ja) | 2014-05-05 | 2019-05-29 | リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ | ＲＯＲγのアゴニストとしての使用及び疾患治療のためのベンゼンスルホンアミド及び関連化合物 |
| US9896441B2 (en) | 2014-05-05 | 2018-02-20 | Lycera Corporation | Tetrahydroquinoline sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease |
| EP3166630A4 (en) | 2014-07-07 | 2018-03-28 | Duke University | Vaccines against an oncogenic isoform of esr1 and methods of using the same |
| US20170196953A1 (en) | 2014-07-07 | 2017-07-13 | Duke University | VACCINES AGAINST AN ONCOGENIC ISOFORM OF HER2 (ErbB2) AND METHODS OF USING THE SAME |
| EP3223848B1 (en) | 2014-11-27 | 2024-11-27 | Zymeworks BC Inc. | Methods of using bispecific antigen-binding constructs targeting her2 |
| JP2018515491A (ja) | 2015-05-05 | 2018-06-14 | リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ | ＲＯＲγの作動薬及び疾患の療法として使用するジヒドロ−２Ｈ−ベンゾ［ｂ］［１，４］オキサジンスルホンアミド及び関連化合物 |
| KR20180025894A (ko) | 2015-06-11 | 2018-03-09 | 라이세라 코퍼레이션 | Rory의 작용제로서 사용하기 위한 아릴 디히드로-2h-벤조[b][1,4]옥사진 술폰아미드 및 관련 화합물 및 질환의 치료 |
| FI126633B (en) | 2015-07-10 | 2017-03-15 | Next Biomed Therapies Oy | Method for the preparation of a library of derivatives of the SH3 domain of recombinant nephrocystin (NPHP1) |
| WO2017120576A1 (en) * | 2016-01-07 | 2017-07-13 | Duke University | Cancer vaccines and methods of delivery |
| US10487143B2 (en) | 2016-10-05 | 2019-11-26 | Duke University | Vaccines against HER3 antigens and methods of using the same |
| US11224665B2 (en) | 2016-10-05 | 2022-01-18 | Duke University | Mitochondrial antiviral signaling (MAVS) protein compositions and methods of using the same |
| JP7313684B2 (ja) | 2016-11-21 | 2023-07-25 | キュレアブ ゲーエムベーハー | 抗ｇｐ７３抗体及びイムノコンジュゲート |
| US10722589B2 (en) | 2017-04-03 | 2020-07-28 | Covagen Ag | FGFR3 binding molecules |
| US20190153096A1 (en) | 2017-10-02 | 2019-05-23 | Covagen Ag | Cd3/cd33 bispecific binding molecules |
| US20190100587A1 (en) | 2017-10-02 | 2019-04-04 | Covagen Ag | IgG1 Fc MUTANTS WITH ABLATED EFFECTOR FUNCTIONS |
| EP3735422A1 (en) | 2018-01-05 | 2020-11-11 | AC Immune SA | Misfolded tdp-43 binding molecules |
| EP3752530A1 (en) | 2018-02-14 | 2020-12-23 | ABBA Therapeutics AG | Anti-human pd-l2 antibodies |
| RU2018111298A (ru) * | 2018-03-29 | 2019-10-01 | Закрытое Акционерное Общество "Биокад" | Биспецифическое антитело, которое специфично связывается с IV и II cубдоменами внеклеточного домена HER2 человека |
| KR20210154179A (ko) | 2019-04-18 | 2021-12-20 | 에이씨 이뮨 에스.에이. | 치료 및 진단용 신규한 분자 |
| KR20220012270A (ko) | 2019-05-23 | 2022-02-03 | 에이씨 이뮨 에스.에이. | 항-tdp-43 결합 분자 및 이의 용도 |
| JP2022537337A (ja) | 2019-06-18 | 2022-08-25 | マックス－プランク－ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ | 金属錯体試薬を介するＨｉｓタグ付タンパク質などの標的分子への標識および／または担体の部位特異的、速度論的に不活性なコンジュゲーション |
| WO2021099484A1 (en) | 2019-11-20 | 2021-05-27 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Archaeal peptide recombinase – a novel peptide ligating enzyme |
| CA3164226A1 (en) | 2019-12-11 | 2021-06-17 | Cilag Gmbh International | Multispecific binding molecules comprising ltbr and edb binding domains and uses thereof |
| JP2023536366A (ja) | 2020-08-07 | 2023-08-24 | エフ． ホフマン－ラ ロシュ アーゲー | タンパク質組成物を製造するための方法 |
| EP4196162A1 (en) | 2020-08-14 | 2023-06-21 | AC Immune SA | Humanized anti-tdp-43 binding molecules and uses thereof |
| WO2022043517A2 (en) | 2020-08-27 | 2022-03-03 | Cureab Gmbh | Anti-golph2 antibodies for macrophage and dendritic cell differentiation |
| EP4229082A1 (en) | 2020-10-16 | 2023-08-23 | AC Immune SA | Antibodies binding to alpha-synuclein for therapy and diagnosis |
| EP4405396A2 (en) | 2021-09-20 | 2024-07-31 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of her2 positive cancer |
| AR127692A1 (es) | 2021-11-16 | 2024-02-21 | Ac Immune Sa | Anticuerpos anti-asc para uso en tratamientos antiinflamatorios |
| US20250034559A1 (en) | 2021-11-17 | 2025-01-30 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
| CR20240378A (es) | 2022-02-16 | 2024-10-03 | Ac Immune Sa | Moléculas de unión anti -tdp-43 humanizadas y usos de las mismas |
| EP4504775A1 (en) | 2022-04-08 | 2025-02-12 | AC Immune SA | Anti-tdp-43 binding molecules |
| WO2023220695A2 (en) | 2022-05-13 | 2023-11-16 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of her2 positive cancer |
| WO2024184494A1 (en) | 2023-03-08 | 2024-09-12 | Ac Immune Sa | Anti-tdp-43 binding molecules and uses thereof |
| WO2025122634A1 (en) | 2023-12-05 | 2025-06-12 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
| WO2025221728A2 (en) | 2024-04-15 | 2025-10-23 | Janssen Biotech, Inc. | Ltbr binding molecules and uses thereof |
| WO2026013218A1 (en) | 2024-07-10 | 2026-01-15 | Ac Immune Sa | Anti-tdp-43 vectors, binding molecules and uses thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184205B1 (en) | 1994-07-22 | 2001-02-06 | University Of North Carolina At Chapel Hill | GRB2 SH3 binding peptides and methods of isolating and using same |
| US5922845A (en) | 1996-07-11 | 1999-07-13 | Medarex, Inc. | Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies |
| US7332585B2 (en) | 2002-04-05 | 2008-02-19 | The Regents Of The California University | Bispecific single chain Fv antibody molecules and methods of use thereof |
| SV2006002143A (es) * | 2004-06-16 | 2006-01-26 | Genentech Inc | Uso de un anticuerpo para el tratamiento del cancer resistente al platino |
| KR20140032004A (ko) * | 2004-07-22 | 2014-03-13 | 제넨테크, 인크. | Ｈｅｒ２ 항체 조성물 |
| WO2006028956A2 (en) | 2004-09-02 | 2006-03-16 | Genentech, Inc. | Anti-fc-gamma riib receptor antibody and uses therefor |
| EP1892248A1 (en) * | 2006-08-21 | 2008-02-27 | Eidgenössische Technische Hochschule Zürich | Specific and high affinity binding proteins comprising modified SH3 domains of FYN kinase |
| US9513296B2 (en) | 2006-08-21 | 2016-12-06 | Eidgenoessische Technische Hochschule Zurich | Specific and high affinity binding proteins comprising modified SH3 domains of Fyn kinase |
| KR20100058509A (ko) | 2007-07-31 | 2010-06-03 | 메디뮨 엘엘씨 | 다중특이적 에피토프 결합 단백질 및 이의 용도 |
| MX2010003718A (es) * | 2007-10-19 | 2010-04-21 | Genentech Inc | Anticuerpos anti-tenb2 producidos por ingenieria de cisteina y conjugados de farmaco y anticuerpo. |
| EP2464663A4 (en) * | 2009-08-13 | 2013-05-29 | Massachusetts Inst Technology | MANIPULATED PROTEINS WITH MUTANT FIBRONECTIN DOMAINS |
| MX2012002428A (es) * | 2009-08-27 | 2012-09-12 | Covagen Ag | Compuestos de union il-17 y usos medicos de los mismos. |
| EP2507381A4 (en) * | 2009-12-04 | 2016-07-20 | Hoffmann La Roche | MULTISPECIFIC ANTIBODIES, ANTIBODY ANALOGS, COMPOSITIONS AND METHODS |
| AU2010332932B2 (en) * | 2009-12-14 | 2013-01-17 | Navigo Proteins Gmbh | Modified ubiquitin proteins having a specific binding activity for the extradomain B of fibronectin |
| CN114805583A (zh) | 2010-05-27 | 2022-07-29 | 根马布股份公司 | 针对her2的单克隆抗体 |
| US20120100166A1 (en) * | 2010-07-15 | 2012-04-26 | Zyngenia, Inc. | Ang-2 Binding Complexes and Uses Thereof |
-
2013
- 2013-03-08 NZ NZ629283A patent/NZ629283A/en not_active IP Right Cessation
- 2013-03-08 CN CN201380014237.9A patent/CN104284675B/zh not_active Expired - Fee Related
- 2013-03-08 EP EP13708424.0A patent/EP2825197B1/en not_active Not-in-force
- 2013-03-08 BR BR112014022932A patent/BR112014022932A2/pt not_active Application Discontinuation
- 2013-03-08 CA CA2865597A patent/CA2865597A1/en not_active Abandoned
- 2013-03-08 AU AU2013231488A patent/AU2013231488B2/en not_active Ceased
- 2013-03-08 RU RU2014141598A patent/RU2627185C1/ru not_active IP Right Cessation
- 2013-03-08 KR KR1020147029084A patent/KR20140135251A/ko not_active Ceased
- 2013-03-08 WO PCT/EP2013/054768 patent/WO2013135588A1/en not_active Ceased
- 2013-03-08 US US14/385,729 patent/US9593314B2/en not_active Expired - Fee Related
- 2013-03-08 MX MX2014011066A patent/MX354717B/es active IP Right Grant
- 2013-03-08 JP JP2014561381A patent/JP6325463B2/ja not_active Expired - Fee Related
-
2017
- 2017-03-09 US US15/454,769 patent/US20170281768A1/en not_active Abandoned
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