JP2015514681A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015514681A5 JP2015514681A5 JP2014551482A JP2014551482A JP2015514681A5 JP 2015514681 A5 JP2015514681 A5 JP 2015514681A5 JP 2014551482 A JP2014551482 A JP 2014551482A JP 2014551482 A JP2014551482 A JP 2014551482A JP 2015514681 A5 JP2015514681 A5 JP 2015514681A5
- Authority
- JP
- Japan
- Prior art keywords
- hydroxy
- pharmaceutical composition
- alkyl
- composition according
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000000217 alkyl group Chemical group 0.000 claims 8
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 125000003545 alkoxy group Chemical group 0.000 claims 6
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- 208000002551 irritable bowel syndrome Diseases 0.000 claims 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 4
- 206010012735 Diarrhoea Diseases 0.000 claims 4
- 229910052736 halogen Inorganic materials 0.000 claims 4
- 150000002367 halogens Chemical class 0.000 claims 4
- 125000000623 heterocyclic group Chemical group 0.000 claims 4
- 150000002431 hydrogen Chemical class 0.000 claims 4
- 125000004043 oxo group Chemical group O=* 0.000 claims 4
- 125000004423 acyloxy group Chemical group 0.000 claims 3
- 150000001338 aliphatic hydrocarbons Chemical group 0.000 claims 3
- 125000003118 aryl group Chemical group 0.000 claims 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 2
- 125000004104 aryloxy group Chemical group 0.000 claims 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 2
- 229930195729 fatty acid Natural products 0.000 claims 2
- 239000000194 fatty acid Substances 0.000 claims 2
- 150000004665 fatty acids Chemical class 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 125000001820 oxy group Chemical group [*:1]O[*:2] 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 229920006395 saturated elastomer Polymers 0.000 claims 2
- 229910052717 sulfur Chemical group 0.000 claims 2
- 239000011593 sulfur Chemical group 0.000 claims 2
- 239000004215 Carbon black (E152) Substances 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 150000001721 carbon Chemical group 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 125000004122 cyclic group Chemical group 0.000 claims 1
- 229930195733 hydrocarbon Natural products 0.000 claims 1
- 150000002430 hydrocarbons Chemical class 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 1
- WGFOBBZOWHGYQH-MXHNKVEKSA-N lubiprostone Chemical group O1[C@](C(F)(F)CCCC)(O)CC[C@@H]2[C@@H](CCCCCCC(O)=O)C(=O)C[C@H]21 WGFOBBZOWHGYQH-MXHNKVEKSA-N 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261637082P | 2012-04-23 | 2012-04-23 | |
| US61/637,082 | 2012-04-23 | ||
| US201261718924P | 2012-10-26 | 2012-10-26 | |
| US61/718,924 | 2012-10-26 | ||
| PCT/JP2013/062309 WO2013161973A1 (en) | 2012-04-23 | 2013-04-19 | Method for treating irritable bowel syndrome with diarrhea |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015514681A JP2015514681A (ja) | 2015-05-21 |
| JP2015514681A5 true JP2015514681A5 (https=) | 2016-06-02 |
Family
ID=49380683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014551482A Pending JP2015514681A (ja) | 2012-04-23 | 2013-04-19 | 下痢を伴う過敏性腸症候群の処置方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20130281526A1 (https=) |
| EP (1) | EP2841065A4 (https=) |
| JP (1) | JP2015514681A (https=) |
| CN (2) | CN108685929A (https=) |
| CA (1) | CA2870252A1 (https=) |
| TW (1) | TWI594751B (https=) |
| WO (1) | WO2013161973A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR105029A1 (es) * | 2015-06-19 | 2017-08-30 | Sucampo Ag | Composición farmacéutica que comprende derivado de ácido graso |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1575596B1 (en) * | 2002-12-27 | 2016-06-22 | Sucampo AG | Derivatives of prostaglandins for treating irritable bowel syndrome and/or functional dyspepsia |
| TWI387454B (zh) * | 2004-09-02 | 2013-03-01 | 蘇坎波公司 | 治療胃腸道疾病之方法及組成物 |
| US20070254050A1 (en) * | 2006-05-01 | 2007-11-01 | Quart Barry D | Method for treatment of diarrhea-predominant irritable bowel syndrome |
| JP5905198B2 (ja) * | 2007-10-01 | 2016-04-20 | ザ ユニヴァーシティー オヴ シカゴ | 薬剤誘発性吐き気のオピオイド拮抗薬による治療 |
| CN101318948B (zh) * | 2008-04-01 | 2011-04-27 | 上海天伟生物制药有限公司 | 鲁比前列酮晶体、其制备方法及用途 |
| WO2009131200A1 (ja) * | 2008-04-25 | 2009-10-29 | 協和発酵キリン株式会社 | 過敏性腸症候群治療剤 |
| US8980325B2 (en) * | 2008-05-01 | 2015-03-17 | Revalesio Corporation | Compositions and methods for treating digestive disorders |
| US20110136788A1 (en) * | 2008-08-07 | 2011-06-09 | Minoru Maruyama | Therapeutic agent for irritable bowel syndrome |
| WO2010151699A1 (en) * | 2009-06-25 | 2010-12-29 | Prometheus Laboratories Inc. | Methods for diagnosing irritable bowel syndrome |
| US20110034424A1 (en) * | 2009-06-30 | 2011-02-10 | Sucampo Ag | Method for the long term nsaid use |
| IT1402047B1 (it) * | 2010-10-19 | 2013-08-28 | Cross Pharma Sa | Uso del mexiprostil nel trattamento delle malattie infiammatorie intestinali |
-
2013
- 2013-04-19 CN CN201810359931.9A patent/CN108685929A/zh active Pending
- 2013-04-19 CA CA2870252A patent/CA2870252A1/en not_active Abandoned
- 2013-04-19 WO PCT/JP2013/062309 patent/WO2013161973A1/en not_active Ceased
- 2013-04-19 EP EP13780861.4A patent/EP2841065A4/en not_active Withdrawn
- 2013-04-19 CN CN201380032872.XA patent/CN104379140A/zh active Pending
- 2013-04-19 JP JP2014551482A patent/JP2015514681A/ja active Pending
- 2013-04-22 US US13/867,583 patent/US20130281526A1/en not_active Abandoned
- 2013-04-22 TW TW102114151A patent/TWI594751B/zh not_active IP Right Cessation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR083760A1 (es) | Agentes antibacterianos y composiciones farmaceuticas | |
| WO2013121449A8 (en) | Compositions and methods for the modulation of specific amidases for n-acylethanolamines for use in the therapy of inflammatory diseases | |
| AR085615A1 (es) | Derivados de fluoropiridinona utiles como agentes antibacterianos y composiciones farmaceuticas que los contienen | |
| JP2008531468A5 (https=) | ||
| MD20180040A2 (ro) | Inhibitori ai virusului hepatic C | |
| JP2004527567A5 (https=) | ||
| JP2013518832A5 (https=) | ||
| RU2018113296A (ru) | Фармацевтическая композиция, содержащая 11-дезокси-простагландиновое соединение и способ стабилизации этого соединения | |
| JP2017503760A5 (https=) | ||
| JP2014511825A5 (https=) | ||
| NZ712660A (en) | Dicarboxylic acid compound | |
| BR112014004523A2 (pt) | composto e composição aromatizante | |
| RU2012146325A (ru) | Терапевтическое средство или профилактическое средство для лечения фибромиалгии | |
| NZ593763A (en) | Method of preparing (+)-1,4-dihydro-7-[(3s,4s)-3methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid | |
| RU2013151166A (ru) | Способ модуляции активности цитокинов | |
| JP2015514681A5 (https=) | ||
| JP2008528440A5 (https=) | ||
| BR112012029033A2 (pt) | compostos | |
| RU2015108907A (ru) | Способы и фармацевтические композиции для лечения синдрома дауна | |
| JP2014237711A5 (https=) | ||
| JP2014510022A5 (https=) | ||
| MX2013013262A (es) | Derivados de ciclododecadienona como ingredientes de perfumado. | |
| JP2016528165A5 (https=) | ||
| JP2014527048A5 (https=) | ||
| RU2012136457A (ru) | Новые композиции для уменьшения аb 42 синтеза и их применение в лечении болезни альцгеймера (ad) |