JP2016528165A5 - - Google Patents
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- Publication number
- JP2016528165A5 JP2016528165A5 JP2016509176A JP2016509176A JP2016528165A5 JP 2016528165 A5 JP2016528165 A5 JP 2016528165A5 JP 2016509176 A JP2016509176 A JP 2016509176A JP 2016509176 A JP2016509176 A JP 2016509176A JP 2016528165 A5 JP2016528165 A5 JP 2016528165A5
- Authority
- JP
- Japan
- Prior art keywords
- hydroxy
- alkyl
- aliphatic hydrocarbon
- composition according
- cyclo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000000217 alkyl group Chemical group 0.000 claims 9
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 8
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 6
- 125000003545 alkoxy group Chemical group 0.000 claims 6
- 229910052736 halogen Inorganic materials 0.000 claims 6
- 150000002367 halogens Chemical class 0.000 claims 6
- 125000001931 aliphatic group Chemical group 0.000 claims 4
- 125000000623 heterocyclic group Chemical group 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 4
- 125000004043 oxo group Chemical group O=* 0.000 claims 4
- 229920006395 saturated elastomer Polymers 0.000 claims 4
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 3
- 125000004423 acyloxy group Chemical group 0.000 claims 3
- 125000003118 aryl group Chemical group 0.000 claims 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 3
- 150000002431 hydrogen Chemical class 0.000 claims 3
- 229910052757 nitrogen Inorganic materials 0.000 claims 3
- 229910052760 oxygen Inorganic materials 0.000 claims 3
- 239000001301 oxygen Substances 0.000 claims 3
- 229910052717 sulfur Inorganic materials 0.000 claims 3
- 239000011593 sulfur Substances 0.000 claims 3
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 claims 2
- 125000004104 aryloxy group Chemical group 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 150000001721 carbon Chemical group 0.000 claims 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 2
- 229930195729 fatty acid Natural products 0.000 claims 2
- 239000000194 fatty acid Substances 0.000 claims 2
- 150000004665 fatty acids Chemical class 0.000 claims 2
- 125000001820 oxy group Chemical group [*:1]O[*:2] 0.000 claims 2
- WIUGSPUQKXSPDJ-JDFMTEHDSA-N (e)-7-[(1r,2r)-2-(4,4-difluoro-3-oxooctyl)-5-oxocyclopentyl]hept-2-enoic acid Chemical compound CCCCC(F)(F)C(=O)CC[C@H]1CCC(=O)[C@@H]1CCCC\C=C\C(O)=O WIUGSPUQKXSPDJ-JDFMTEHDSA-N 0.000 claims 1
- CTQWVWWSERVGET-HZPDHXFCSA-N 7-[(1r,2r)-2-(4,4-difluoro-3-oxooctyl)-5-oxocyclopentyl]heptanoic acid Chemical group CCCCC(F)(F)C(=O)CC[C@H]1CCC(=O)[C@@H]1CCCCCCC(O)=O CTQWVWWSERVGET-HZPDHXFCSA-N 0.000 claims 1
- 208000002193 Pain Diseases 0.000 claims 1
- 125000002947 alkylene group Chemical group 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 1
- 208000004296 neuralgia Diseases 0.000 claims 1
- 208000021722 neuropathic pain Diseases 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361868750P | 2013-08-22 | 2013-08-22 | |
| US61/868,750 | 2013-08-22 | ||
| US201361918124P | 2013-12-19 | 2013-12-19 | |
| US61/918,124 | 2013-12-19 | ||
| PCT/JP2014/072508 WO2015025980A1 (en) | 2013-08-22 | 2014-08-21 | Method for treating neuropathic pain |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016528165A JP2016528165A (ja) | 2016-09-15 |
| JP2016528165A5 true JP2016528165A5 (https=) | 2017-09-28 |
| JP6641263B2 JP6641263B2 (ja) | 2020-02-05 |
Family
ID=52480928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016509176A Expired - Fee Related JP6641263B2 (ja) | 2013-08-22 | 2014-08-21 | 神経障害性疼痛の処置方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20150057351A1 (https=) |
| EP (1) | EP3035925A4 (https=) |
| JP (1) | JP6641263B2 (https=) |
| WO (1) | WO2015025980A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20180058758A (ko) | 2015-09-22 | 2018-06-01 | 그레이버그 비젼, 인크. | 안구 장애의 치료를 위한 화합물 및 조성물 |
| WO2018129313A1 (en) * | 2017-01-06 | 2018-07-12 | Clexio Biosciences Ltd. | Topical detomidine formulations |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5166174A (en) | 1987-01-28 | 1992-11-24 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti-ulcers containing same |
| CA1322749C (en) | 1987-01-28 | 1993-10-05 | Ryuzo Ueno | Prostaglandins of the d series, and tranquilizers and soporifics containing the same |
| US5221763A (en) | 1987-04-30 | 1993-06-22 | R-Tech Ueno, Ltd. | Prostaglandins of the F series |
| TW224942B (https=) | 1990-04-04 | 1994-06-11 | Adka Ueno Kk | |
| CA2150287C (en) | 1994-06-03 | 2004-08-10 | Ryuji Ueno | Agent for treating hepato-biliary diseases |
| JP3187438B2 (ja) | 1996-06-10 | 2001-07-11 | 株式会社アールテック・ウエノ | エンドセリン拮抗剤 |
| AU7349301A (en) * | 2000-07-21 | 2002-02-05 | Ortho Mcneil Pharm Inc | Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain |
| PL365442A1 (en) * | 2001-02-22 | 2005-01-10 | Ono Pharmaceutical Co, Ltd. | Medicinal compositions comprising diclofenac and ornoprostil |
| EP1420794B1 (en) * | 2001-08-31 | 2017-12-27 | Sucampo AG | Prostaglandin analogs as chloride channel openers |
| BRPI0510665A (pt) * | 2004-05-11 | 2007-12-04 | Incyte Corp | 3-(4-heteroarilcicloexilamino) ciclopentano-carboxiamidas como moduladores de receptores de quimiocinas |
| DE602006018583D1 (de) * | 2005-03-04 | 2011-01-13 | Sucampo Ag | Verfahren und zusammensetzung zur behandlung von peripheren gefässkrankheiten |
| US20090030072A1 (en) * | 2007-07-03 | 2009-01-29 | Sucampo Ag | Pharmaceutical combination of opioid and prostaglandin compound |
| KR20100038061A (ko) * | 2008-10-02 | 2010-04-12 | 도쿠리츠다이가쿠호징 가나자와다이가쿠 | 리마프로스트를 함유하는, 암화학 요법에 기인하는 말초신경장애 예방, 치료 및/또는 증상 경감제 |
| US20110034424A1 (en) * | 2009-06-30 | 2011-02-10 | Sucampo Ag | Method for the long term nsaid use |
| RU2648474C2 (ru) * | 2011-08-05 | 2018-03-26 | Сукампо Аг | Способ лечения шизофрении |
-
2014
- 2014-08-20 US US14/464,232 patent/US20150057351A1/en not_active Abandoned
- 2014-08-21 EP EP14838126.2A patent/EP3035925A4/en not_active Withdrawn
- 2014-08-21 WO PCT/JP2014/072508 patent/WO2015025980A1/en not_active Ceased
- 2014-08-21 JP JP2016509176A patent/JP6641263B2/ja not_active Expired - Fee Related
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