CN108685929A - 用于治疗具有腹泻的肠易激综合征的方法 - Google Patents

用于治疗具有腹泻的肠易激综合征的方法 Download PDF

Info

Publication number
CN108685929A
CN108685929A CN201810359931.9A CN201810359931A CN108685929A CN 108685929 A CN108685929 A CN 108685929A CN 201810359931 A CN201810359931 A CN 201810359931A CN 108685929 A CN108685929 A CN 108685929A
Authority
CN
China
Prior art keywords
alkyl
diarrhea
bowel syndrome
irritable bowel
fatty acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810359931.9A
Other languages
English (en)
Chinese (zh)
Inventor
上野隆司
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sucampo GmbH
Original Assignee
Sucampo GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sucampo GmbH filed Critical Sucampo GmbH
Publication of CN108685929A publication Critical patent/CN108685929A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201810359931.9A 2012-04-23 2013-04-19 用于治疗具有腹泻的肠易激综合征的方法 Pending CN108685929A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261637082P 2012-04-23 2012-04-23
US61/637082 2012-04-23
US201261718924P 2012-10-26 2012-10-26
US61/718924 2012-10-26
CN201380032872.XA CN104379140A (zh) 2012-04-23 2013-04-19 用于治疗具有腹泻的肠易激综合征的方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201380032872.XA Division CN104379140A (zh) 2012-04-23 2013-04-19 用于治疗具有腹泻的肠易激综合征的方法

Publications (1)

Publication Number Publication Date
CN108685929A true CN108685929A (zh) 2018-10-23

Family

ID=49380683

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201810359931.9A Pending CN108685929A (zh) 2012-04-23 2013-04-19 用于治疗具有腹泻的肠易激综合征的方法
CN201380032872.XA Pending CN104379140A (zh) 2012-04-23 2013-04-19 用于治疗具有腹泻的肠易激综合征的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201380032872.XA Pending CN104379140A (zh) 2012-04-23 2013-04-19 用于治疗具有腹泻的肠易激综合征的方法

Country Status (7)

Country Link
US (1) US20130281526A1 (https=)
EP (1) EP2841065A4 (https=)
JP (1) JP2015514681A (https=)
CN (2) CN108685929A (https=)
CA (1) CA2870252A1 (https=)
TW (1) TWI594751B (https=)
WO (1) WO2013161973A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR105029A1 (es) * 2015-06-19 2017-08-30 Sucampo Ag Composición farmacéutica que comprende derivado de ácido graso

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040138308A1 (en) * 2002-12-27 2004-07-15 Sucampo Ag Method for treating abdominal discomfort
WO2006025599A1 (en) * 2004-09-02 2006-03-09 Sucampo Ag Prostaglandin derivatives for treating gastrointestinal disorder
WO2009045985A1 (en) * 2007-10-01 2009-04-09 The University Of Chicago Treatment of drug-induced nausea with opioid antagonists
WO2009131200A1 (ja) * 2008-04-25 2009-10-29 協和発酵キリン株式会社 過敏性腸症候群治療剤
WO2011002100A1 (en) * 2009-06-30 2011-01-06 Sucampo Ag Medicament for the long term nsaid use
EP2322222A1 (en) * 2008-08-07 2011-05-18 Takeda Pharmaceutical Company Limited Therapeutic agent for irritable bowel syndrome
CN102076327A (zh) * 2008-05-01 2011-05-25 利发利希奥公司 治疗消化功能紊乱的组合物和方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070254050A1 (en) * 2006-05-01 2007-11-01 Quart Barry D Method for treatment of diarrhea-predominant irritable bowel syndrome
CN101318948B (zh) * 2008-04-01 2011-04-27 上海天伟生物制药有限公司 鲁比前列酮晶体、其制备方法及用途
WO2010151699A1 (en) * 2009-06-25 2010-12-29 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
IT1402047B1 (it) * 2010-10-19 2013-08-28 Cross Pharma Sa Uso del mexiprostil nel trattamento delle malattie infiammatorie intestinali

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040138308A1 (en) * 2002-12-27 2004-07-15 Sucampo Ag Method for treating abdominal discomfort
US20100298424A1 (en) * 2002-12-27 2010-11-25 Sucampo Ag Method for treating abdominal discomfort
WO2006025599A1 (en) * 2004-09-02 2006-03-09 Sucampo Ag Prostaglandin derivatives for treating gastrointestinal disorder
WO2009045985A1 (en) * 2007-10-01 2009-04-09 The University Of Chicago Treatment of drug-induced nausea with opioid antagonists
WO2009131200A1 (ja) * 2008-04-25 2009-10-29 協和発酵キリン株式会社 過敏性腸症候群治療剤
CN102076327A (zh) * 2008-05-01 2011-05-25 利发利希奥公司 治疗消化功能紊乱的组合物和方法
EP2322222A1 (en) * 2008-08-07 2011-05-18 Takeda Pharmaceutical Company Limited Therapeutic agent for irritable bowel syndrome
WO2011002100A1 (en) * 2009-06-30 2011-01-06 Sucampo Ag Medicament for the long term nsaid use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WILLIAMD.CHEY ET AL: "What Symptoms Drive Global Symptom Improvement with Lubiprostone in Patients with Irritable Bowel Syndrome and Constipation: Data from Two Multicenter, Randomized, Placebo-Controlled Trials", 《GASTROENTEROLOGY & HEPATOLOGY》 *

Also Published As

Publication number Publication date
TWI594751B (zh) 2017-08-11
TW201347757A (zh) 2013-12-01
CN104379140A (zh) 2015-02-25
EP2841065A1 (en) 2015-03-04
EP2841065A4 (en) 2015-09-16
JP2015514681A (ja) 2015-05-21
US20130281526A1 (en) 2013-10-24
CA2870252A1 (en) 2013-10-31
WO2013161973A1 (en) 2013-10-31

Similar Documents

Publication Publication Date Title
KR101164838B1 (ko) 복부 불쾌감 치료용 프로스타글랜딘의 유도체
JP6408426B2 (ja) 胃腸障害処置用プロスタグランジン誘導体
CN101686984A (zh) Nsaid与前列腺素化合物的药物组合
JP2010502568A (ja) 消化管の重炭酸分泌を促進するための方法および組成物
AU2003274735A1 (en) Prostaglandin compounds for the treatment of obesity
CN101827598B (zh) 阿片样物质与前列腺素化合物的药物组合
CN108685929A (zh) 用于治疗具有腹泻的肠易激综合征的方法
JP6641263B2 (ja) 神経障害性疼痛の処置方法
JP6193230B2 (ja) 統合失調症の処置方法
US20100305203A1 (en) Method for modulating claudin mediated functions
US8569279B2 (en) Method for modulating claudin mediated functions
US20120277299A1 (en) Method for modulating ion transporter
US20160120840A1 (en) Method and composition for treating nonerosive reflux disease
RU2392941C2 (ru) Производные простагландинов для лечения желудочно-кишечного нарушения

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20181023

RJ01 Rejection of invention patent application after publication