JP2015513370A5 - - Google Patents

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Publication number
JP2015513370A5
JP2015513370A5 JP2015500570A JP2015500570A JP2015513370A5 JP 2015513370 A5 JP2015513370 A5 JP 2015513370A5 JP 2015500570 A JP2015500570 A JP 2015500570A JP 2015500570 A JP2015500570 A JP 2015500570A JP 2015513370 A5 JP2015513370 A5 JP 2015513370A5
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JP
Japan
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brain injury
patient
post
isoform
gfap
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JP2015500570A
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Japanese (ja)
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JP2015513370A (ja
JP6392202B2 (ja
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Priority claimed from PCT/US2013/031012 external-priority patent/WO2013138509A1/en
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Publication of JP2015513370A5 publication Critical patent/JP2015513370A5/ja
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JP2015500570A 2012-03-13 2013-03-13 脳損傷または神経変性のバイオマーカーとしてのシトルリン化脳および神経タンパク質 Active JP6392202B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261610034P 2012-03-13 2012-03-13
US61/610,034 2012-03-13
PCT/US2013/031012 WO2013138509A1 (en) 2012-03-13 2013-03-13 Citrullinated brain and neurological proteins as biomarkers of brain injury or neurodegeneration

Publications (3)

Publication Number Publication Date
JP2015513370A JP2015513370A (ja) 2015-05-11
JP2015513370A5 true JP2015513370A5 (enExample) 2016-05-12
JP6392202B2 JP6392202B2 (ja) 2018-09-19

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JP2015500570A Active JP6392202B2 (ja) 2012-03-13 2013-03-13 脳損傷または神経変性のバイオマーカーとしてのシトルリン化脳および神経タンパク質

Country Status (5)

Country Link
US (4) US9709573B2 (enExample)
EP (1) EP2825893A4 (enExample)
JP (1) JP6392202B2 (enExample)
HK (1) HK1206425A1 (enExample)
WO (1) WO2013138509A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013138509A1 (en) * 2012-03-13 2013-09-19 The Johns Hopkins University Citrullinated brain and neurological proteins as biomarkers of brain injury or neurodegeneration
US20160125454A1 (en) * 2014-11-04 2016-05-05 Yahoo! Inc. Systems and methods for managing advertising campaigns
US20180024145A1 (en) 2015-02-05 2018-01-25 Immunarray USA, Inc. Methods and compositions for diagnosing brain injury or neurodegeneration
WO2016205730A1 (en) * 2015-06-18 2016-12-22 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Citrullinated proteins and their breakdown products as tbi biomarkers
JP6325177B2 (ja) * 2015-10-14 2018-05-16 公立大学法人横浜市立大学 腎癌薬物療法の効果判定のための血中バイオマーカー
US11143662B2 (en) 2016-06-30 2021-10-12 Brainbox Solutions, Inc. Circulating biomarker levels for diagnosis and risk-stratification of traumatic brain injury
EP3499230A4 (en) * 2016-08-09 2020-07-29 Otsuka Pharmaceutical Co., Ltd. Method for assisting diagnosis of alzheimer's disease using urine biomarker
KR101834724B1 (ko) 2016-08-11 2018-03-06 한림대학교 산학협력단 시트룰린화 미엘린 염기성 단백질에 대한 모노클론 항체 및 이를 이용한 신경 퇴행성 질환 진단 킷트
WO2018048884A1 (en) 2016-09-09 2018-03-15 Mayo Foundation For Medical Education And Research Methods and materials for identifying and treating autoimmune gfap astrocytopathy
US20180284118A1 (en) * 2017-04-04 2018-10-04 The Johns Hopkins University Anti-pad2 antibody for treating and evaluating autoimmune and inflammatory diseases
WO2018217792A1 (en) 2017-05-23 2018-11-29 Immunarray USA, Inc. Biomarker levels and neuroimaging for detecting, monitoring and treating brain injury or trauma
JP6344783B1 (ja) * 2017-06-21 2018-06-20 エフビートライアングル株式会社 ガス分析に基づく評価システム
US20210270847A1 (en) * 2018-08-17 2021-09-02 University Of Florida Research Foundation, Incorporated Protein and peptide biomarkers for traumatic injury to the central nervous system
US20220146527A1 (en) * 2019-09-17 2022-05-12 Chang Gung University Method of creating characteristic profiles of mass spectra and identification model for analyzing and identifying features of microorganisms
CN110988207B (zh) * 2019-12-17 2021-03-23 厦门历思科技服务有限公司 基于人体摄入物质检测的监测方法
US11835519B2 (en) * 2019-12-17 2023-12-05 Euroimmun Medizinische Labordiagnostika Ag Autoantibodies to Septin-7 and diagnosis of neurological disease
EP3940383A1 (en) * 2020-07-16 2022-01-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the outcome of patients having acute ischemic stroke
US11940450B2 (en) 2021-03-16 2024-03-26 University Of Connecticut Biomarker panel for non-invasive diagnosis of congenital renal dysfunction
CN120712049A (zh) 2022-12-15 2025-09-26 阿达普提克斯生物科学公司 用于分析物检测的系统和方法

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2263063C (en) 1999-02-26 2004-08-10 Skye Pharmatech Incorporated Method for diagnosing and distinguishing stroke and diagnostic devices for use therein
US6780606B1 (en) 1999-02-26 2004-08-24 Synx Pharma, Inc. Method for diagnosing and distinguishing stroke and diagnostic devices for use therein
US20030077590A1 (en) 2000-09-22 2003-04-24 Pedersen Finn Skou Methods for diagnosis and treatment of diseases associated with altered expression of neurogranin
WO2002024867A2 (en) 2000-09-22 2002-03-28 University Of Aarhus Novel compositions and methods for lymphoma and leukemia
US6884591B2 (en) 2001-06-25 2005-04-26 The Cleveland Clinic Foundation Peripheral marker of blood brain barrier permeability
US7144708B2 (en) 2001-06-25 2006-12-05 The Cleveland Clinic Foundation Markers of blood barrier disruption and methods of using same
DE60233949D1 (de) 2001-08-20 2009-11-19 Biosite Inc Diagnostische marker für schlaganfall und hirntrauma sowie verfahren zur verwendung davon
US20030040660A1 (en) 2001-08-27 2003-02-27 George Jackowski Method for diagnosing and distinguishing traumatic brain injury and diagnostic devices for use therein
US20070098728A1 (en) 2001-09-24 2007-05-03 Pedersen Finn S Novel compositions and methods in cancer
AU2004216925B2 (en) 2003-03-07 2010-04-22 London Health Sciences Centre Research Inc. Peptides associated with HLA-DR MHC class II molecules involved in autoimmune diseases
EP1519194A1 (en) 2003-09-24 2005-03-30 Roche Diagnostics GmbH Use of gfap for identification of intracerebral hemorrhage
US8492107B2 (en) 2004-04-15 2013-07-23 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for nervous system injury and other neural disorders
EP1745149A4 (en) 2004-04-15 2008-08-06 Univ Florida NEURALE PROTEINS AS BIOMARKERS FOR INJURY TO THE NERVOUS SYSTEM AND OTHER NEURAL DISORDERS
US20140303041A1 (en) 2004-04-15 2014-10-09 University Of Florida Research Foundation Inc. In vitro diagnostic devices for nervous system injury and other neural disorders
WO2005113798A2 (en) 2004-04-15 2005-12-01 University Of Florida Research Foundation, Inc. Proteolytic markers as diagnostic biomarkers for cancer, organ injury and muscle rehabilitation/exercise overtraining
WO2006012351A2 (en) 2004-06-25 2006-02-02 Washington University Markers for brain damage
EP1828403B1 (en) 2004-12-04 2014-08-20 Los Alamos National Security, LLC Protein subcellular localization assays using split fluorescent proteins
US20060257943A1 (en) 2005-01-25 2006-11-16 Cis Biotech, Inc. Ischemic biomarkers and their use to predict adverse neurological events from surgery
US7884260B2 (en) 2005-06-14 2011-02-08 University Of Chicago Cell-based screen for agents useful for reducing neuronal demyelination or promoting neuronal remyelination
GB2428240A (en) 2005-07-14 2007-01-24 Univ Gen Ve Diagnostic method for brain damage-related disorders
US20080026485A1 (en) * 2006-04-18 2008-01-31 Wolfgang Hueber Antibody profiling for determination of patient responsiveness
WO2007136617A2 (en) 2006-05-18 2007-11-29 Walter Reed Army Institute Of Research (Wrair) Endothelial-monocyte activating polypeptide ii, a biomarker for use in diagnosis of brain injury
WO2008046509A1 (en) 2006-10-16 2008-04-24 Bayer Schering Pharma Aktiengesellschaft Ltbp2 as a biomarker, therapeutic and diagnostic target
JP2008157905A (ja) 2006-12-25 2008-07-10 Hectef Standard Reference Center Foundation 添加法による生体試料中蛋白・ペプチドの定量方法
WO2008097618A1 (en) 2007-02-06 2008-08-14 University Of Florida Research Foundation, Inc. Synaptotagmin and collapsin response mediator protein as biomarkers for traumatic brain injury
JP5305259B2 (ja) 2007-12-25 2013-10-02 地方独立行政法人東京都健康長寿医療センター 抗シトルリン化gfapモノクローナル抗体及びその用途
CA2715248A1 (en) 2008-02-04 2009-08-13 Banyan Biomarkers, Inc. Process to diagnose or treat brain injury
EP2294425B1 (en) 2008-05-23 2013-05-22 The Johns Hopkins University Biomarkers for myocardial ischemia
EP2143735A1 (en) 2008-07-10 2010-01-13 Institut Pasteur Variable domains of camelid heavy-chain antibodies directed against glial fibrillary acidic proteins
US20140342381A1 (en) 2008-08-11 2014-11-20 Banyan Biomarkers, Inc. Devices and methods for biomarker detection process and assay of neurological condition
EP3336551B1 (en) * 2008-08-11 2023-05-31 Banyan Biomarkers, Inc. Biomarker detection process and assay of neurological condition
US8119694B2 (en) 2008-08-15 2012-02-21 Arcion Therapeutics, Inc. High concentration local anesthetic formulations
US9063148B2 (en) 2008-10-22 2015-06-23 The Henry M. Jackson Foundation For The Advancement Of Military Medicince, Inc. Immunoassays for citrullinated proteins
US20170315136A9 (en) 2009-06-19 2017-11-02 Banyan Biomarkers, Inc. Biomarker assay of neurological condition
JP5875514B2 (ja) 2009-06-19 2016-03-02 バンヤン・バイオマーカーズ・インコーポレーテッド 神経学的状態のバイオマーカーアッセイ
US10266585B2 (en) 2009-08-28 2019-04-23 The Board Of Regents Of The Univerity Of Texas System Methods of treating brain injury
EP2470211B1 (en) 2009-08-28 2016-01-27 The Board of Regents of The University of Texas System Antibodies that bind tau oligomers
AU2010291933B2 (en) 2009-09-14 2016-09-08 Banyan Biomarkers, Inc. Micro-RNA, autoantibody and protein markers for diagnosis of neuronal injury
GB201008541D0 (en) 2010-05-21 2010-07-07 Univ Geneve Diagnostic methods
WO2012051519A2 (en) * 2010-10-14 2012-04-19 The Johns Hopkins University Biomarkers of brain injury
AU2012211328A1 (en) 2011-01-28 2013-09-19 Cyrex Laboratories, Llc Method for detection of intestinal, and blood-brain barrier permeability and testing materials thereto
EP2707389B1 (en) 2011-05-12 2019-10-30 The Johns Hopkins University Assay reagents for a neurogranin diagnostic kit
WO2012170998A1 (en) 2011-06-10 2012-12-13 Cornell University Immobilized protein system for rapid and enhanced multiplexed diagnostics
WO2013138509A1 (en) * 2012-03-13 2013-09-19 The Johns Hopkins University Citrullinated brain and neurological proteins as biomarkers of brain injury or neurodegeneration
WO2013173596A1 (en) 2012-05-16 2013-11-21 Trustees Of Boston University Chronic traumatic encephalopathy in blast-exposed individuals
US20150141528A1 (en) 2013-05-31 2015-05-21 Banyan Biomarkers, Inc. Neural specific s100b for biomarker assays and devices for detection of a neurological condition
EP3022322A4 (en) 2013-07-17 2017-05-17 The Johns Hopkins University A multi-protein biomarker assay for brain injury detection and outcome
WO2015066211A1 (en) 2013-10-29 2015-05-07 Banyan Biomarkers, Inc. Uch-l1 isoforms, assays and devices for detection of a neurological condition
US10725054B2 (en) 2014-04-08 2020-07-28 University Of Florida Research Foundation, Incorporated Protein biomarkers for acute, subacute and chronic traumatic injuries of the central nervous system
EP3702786A1 (en) 2014-10-06 2020-09-02 Université de Genève Markers and their use in brain injury
EP3029466A1 (en) 2014-12-03 2016-06-08 Fundació Hospital Universitari Vall d' Hebron - Institut de Recerca Methods for differentiating ischemic stroke from hemorrhagic stroke
CA2992343A1 (en) 2015-07-13 2017-01-19 University Of Geneva Biomarker panels for brain injury complications

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