JP2015512403A5 - - Google Patents
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- Publication number
- JP2015512403A5 JP2015512403A5 JP2015503344A JP2015503344A JP2015512403A5 JP 2015512403 A5 JP2015512403 A5 JP 2015512403A5 JP 2015503344 A JP2015503344 A JP 2015503344A JP 2015503344 A JP2015503344 A JP 2015503344A JP 2015512403 A5 JP2015512403 A5 JP 2015512403A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- treatment
- synthetic cationic
- agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 31
- 125000002091 cationic group Chemical group 0.000 claims 9
- 229920000642 polymer Polymers 0.000 claims 9
- 229920001184 polypeptide Polymers 0.000 claims 9
- 102000004196 processed proteins & peptides Human genes 0.000 claims 9
- 108090000765 processed proteins & peptides Proteins 0.000 claims 9
- 208000015181 infectious disease Diseases 0.000 claims 5
- 230000002265 prevention Effects 0.000 claims 4
- 239000003242 anti bacterial agent Substances 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 206010052428 Wound Diseases 0.000 claims 2
- 208000027418 Wounds and injury Diseases 0.000 claims 2
- 125000000539 amino acid group Chemical group 0.000 claims 2
- 230000000844 anti-bacterial effect Effects 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 238000004659 sterilization and disinfection Methods 0.000 claims 2
- 239000004094 surface-active agent Substances 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 1
- 102000004506 Blood Proteins Human genes 0.000 claims 1
- 108010017384 Blood Proteins Proteins 0.000 claims 1
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- 208000008960 Diabetic foot Diseases 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 102000009123 Fibrin Human genes 0.000 claims 1
- 108010073385 Fibrin Proteins 0.000 claims 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 1
- 102000008946 Fibrinogen Human genes 0.000 claims 1
- 108010049003 Fibrinogen Proteins 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 1
- 229940072056 alginate Drugs 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 230000002491 angiogenic effect Effects 0.000 claims 1
- 125000000129 anionic group Chemical group 0.000 claims 1
- 239000000058 anti acne agent Substances 0.000 claims 1
- 230000003214 anti-biofilm Effects 0.000 claims 1
- 230000002924 anti-infective effect Effects 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 229940124340 antiacne agent Drugs 0.000 claims 1
- 229940088710 antibiotic agent Drugs 0.000 claims 1
- 229940030225 antihemorrhagics Drugs 0.000 claims 1
- 239000004599 antimicrobial Substances 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 230000004888 barrier function Effects 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 238000009792 diffusion process Methods 0.000 claims 1
- 239000000975 dye Substances 0.000 claims 1
- 230000008029 eradication Effects 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 229940012952 fibrinogen Drugs 0.000 claims 1
- 239000006260 foam Substances 0.000 claims 1
- 238000009920 food preservation Methods 0.000 claims 1
- -1 food preservation Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 230000023597 hemostasis Effects 0.000 claims 1
- 239000002874 hemostatic agent Substances 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 239000007943 implant Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 239000002831 pharmacologic agent Substances 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 239000004814 polyurethane Substances 0.000 claims 1
- 229920002635 polyurethane Polymers 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- 238000004321 preservation Methods 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002947 procoagulating effect Effects 0.000 claims 1
- 230000000770 proinflammatory effect Effects 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
- 150000003431 steroids Chemical class 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 238000007910 systemic administration Methods 0.000 claims 1
- 238000010610 time kill assay Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 208000019206 urinary tract infection Diseases 0.000 claims 1
- 210000001215 vagina Anatomy 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 230000029663 wound healing Effects 0.000 claims 1
- 239000003357 wound healing promoting agent Substances 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261615150P | 2012-03-23 | 2012-03-23 | |
| US61/615,150 | 2012-03-23 | ||
| US201261625760P | 2012-04-18 | 2012-04-18 | |
| US201261625757P | 2012-04-18 | 2012-04-18 | |
| US61/625,757 | 2012-04-18 | ||
| US61/625,760 | 2012-04-18 | ||
| US201261716242P | 2012-10-19 | 2012-10-19 | |
| US61/716,242 | 2012-10-19 | ||
| PCT/US2013/032535 WO2013142374A1 (en) | 2012-03-23 | 2013-03-15 | Compositions and uses of antimicrobial materials with tissue-compatible properties |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017194019A Division JP2018020175A (ja) | 2012-03-23 | 2017-10-04 | 組織適合特性を有する抗菌剤の組成物および使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015512403A JP2015512403A (ja) | 2015-04-27 |
| JP2015512403A5 true JP2015512403A5 (https=) | 2016-02-04 |
| JP6224069B2 JP6224069B2 (ja) | 2017-11-01 |
Family
ID=49223273
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015503344A Active JP6224069B2 (ja) | 2012-03-23 | 2013-03-15 | 組織適合特性を有する抗菌剤の組成物および使用 |
| JP2017194019A Pending JP2018020175A (ja) | 2012-03-23 | 2017-10-04 | 組織適合特性を有する抗菌剤の組成物および使用 |
| JP2019166236A Active JP7255787B2 (ja) | 2012-03-23 | 2019-09-12 | 組織適合特性を有する抗菌剤の組成物および使用 |
| JP2020184556A Pending JP2021020964A (ja) | 2012-03-23 | 2020-11-04 | 組織適合特性を有する抗菌剤の組成物および使用 |
| JP2022176900A Pending JP2023011850A (ja) | 2012-03-23 | 2022-11-04 | 組織適合特性を有する抗菌剤の組成物および使用 |
| JP2025019121A Pending JP2025065375A (ja) | 2012-03-23 | 2025-02-07 | 組織適合特性を有する抗菌剤の組成物および使用 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017194019A Pending JP2018020175A (ja) | 2012-03-23 | 2017-10-04 | 組織適合特性を有する抗菌剤の組成物および使用 |
| JP2019166236A Active JP7255787B2 (ja) | 2012-03-23 | 2019-09-12 | 組織適合特性を有する抗菌剤の組成物および使用 |
| JP2020184556A Pending JP2021020964A (ja) | 2012-03-23 | 2020-11-04 | 組織適合特性を有する抗菌剤の組成物および使用 |
| JP2022176900A Pending JP2023011850A (ja) | 2012-03-23 | 2022-11-04 | 組織適合特性を有する抗菌剤の組成物および使用 |
| JP2025019121A Pending JP2025065375A (ja) | 2012-03-23 | 2025-02-07 | 組織適合特性を有する抗菌剤の組成物および使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US9446090B2 (https=) |
| EP (2) | EP4516101A3 (https=) |
| JP (6) | JP6224069B2 (https=) |
| KR (2) | KR102141254B1 (https=) |
| CN (1) | CN104582688A (https=) |
| AU (2) | AU2013235336B2 (https=) |
| BR (1) | BR112014023068B1 (https=) |
| CA (1) | CA2867903C (https=) |
| ES (1) | ES2991989T3 (https=) |
| HU (1) | HUE069626T2 (https=) |
| IN (1) | IN2014DN08299A (https=) |
| MX (2) | MX344635B (https=) |
| PL (1) | PL2827841T3 (https=) |
| RU (1) | RU2680959C2 (https=) |
| WO (1) | WO2013142374A1 (https=) |
| ZA (1) | ZA201407121B (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101801521B (zh) | 2007-05-14 | 2015-06-17 | 纽约州立大学研究基金会 | 生物膜中细菌细胞内的生理学分散响应诱导 |
| ES2991989T3 (es) * | 2012-03-23 | 2024-12-05 | Macro Biologics Inc | Composiciones y usos de materiales antimicrobianos con propiedades compatibles con tejidos |
| MX2016010864A (es) | 2014-02-21 | 2017-05-08 | Avadim Tech Inc | Metodo para el mantenimiento de cateteres uretrales. |
| AU2015288635B2 (en) * | 2014-07-11 | 2018-07-26 | Menicon Co., Ltd. | Visibility-ensuring material, and device for discharging visibility-ensuring material |
| WO2016029920A1 (en) * | 2014-08-29 | 2016-03-03 | Aarhus Universitet | Positively charged co-polymers for use as antimicrobial agents |
| BR112017010557A2 (pt) | 2014-11-19 | 2017-12-26 | Avadim Tech Inc | método para a prevenção e tratamento de acne |
| US11285189B2 (en) * | 2017-04-06 | 2022-03-29 | Amicrobe, Inc. | Compositions and uses of locally-applied antimicrobial synthetic cationic polypeptide(s) with enhanced performance and safety |
| GB201711555D0 (en) * | 2017-07-18 | 2017-08-30 | Kent Innovation & Entpr | Antibacterial compounds |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| PL3934753T3 (pl) * | 2019-03-04 | 2026-04-20 | Capretto Ehf. | Usuwanie drobnoustrojów |
| CN109847090B (zh) * | 2019-03-25 | 2021-08-31 | 深圳市康乐美科技有限公司 | 一种具有抗菌、柔软特性的卫生巾 |
| CA3143518A1 (en) | 2019-06-12 | 2020-12-17 | Avadim Health Ip, Inc. | Compositions and methods for the antiseptic cleansing and biofilms treatment of mammalian tissue |
| US20230149333A1 (en) * | 2020-04-08 | 2023-05-18 | Amicrobe, Inc. | Compositions and uses of locally applied synthetic amino acid polymers for prevention and treatment of viral infections |
| CN112048084A (zh) * | 2020-08-21 | 2020-12-08 | 浙江隆泰医疗科技股份有限公司 | 一种低温交联的聚乙烯醇复合抗菌肽材料的制备方法 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU595040B2 (en) | 1986-07-01 | 1990-03-22 | Ici Australia Operations Proprietary Limited | Cyclohexane-1, 3-dione herbicides |
| US5636643A (en) | 1991-11-14 | 1997-06-10 | Wake Forest University | Wound treatment employing reduced pressure |
| US6680365B1 (en) | 1998-03-19 | 2004-01-20 | The Regents Of The University Of California | Methods and compositions for controlled polypeptide synthesis |
| US6686446B2 (en) | 1998-03-19 | 2004-02-03 | The Regents Of The University Of California | Methods and compositions for controlled polypeptide synthesis |
| US6632922B1 (en) | 1998-03-19 | 2003-10-14 | The Regents Of The University Of California | Methods and compositions for controlled polypeptide synthesis |
| TW570805B (en) | 1998-09-01 | 2004-01-11 | Hoffmann La Roche | Water-soluble pharmaceutical composition in an ionic complex |
| US8206749B1 (en) | 1999-02-26 | 2012-06-26 | Novartis Vaccines And Diagnostics, Inc. | Microemulsions with adsorbed macromolecules and microparticles |
| MXPA03002640A (es) | 2000-09-28 | 2003-06-19 | Chiron Corp | Microparticulas para la distribucion de acidos nucleicos heterologos. |
| US6835536B2 (en) * | 2001-08-21 | 2004-12-28 | Micrologix Biotech Inc. | Antimicrobial cationic peptides and formulations thereof |
| US6818732B2 (en) | 2001-08-30 | 2004-11-16 | The Regents Of The University Of California | Transition metal initiators for controlled poly (beta-peptide) synthesis from beta-lactam monomers |
| JP2003171463A (ja) | 2001-12-06 | 2003-06-20 | Chisso Corp | ポリリジン及びその製造法 |
| CA2443472A1 (en) * | 2002-02-07 | 2003-08-14 | Ophtecs Corporation | Liquid formulation for contact lenses |
| CN103405405A (zh) * | 2002-12-09 | 2013-11-27 | 阿布拉西斯生物科学有限责任公司 | 组合物和传递药剂的方法 |
| EP1644382B1 (en) * | 2003-07-11 | 2008-03-05 | Theravance, Inc. | Cross-linked glycopeptide-cephalosporin antibiotics |
| US7314857B2 (en) * | 2003-08-25 | 2008-01-01 | Kane Biotech Inc. | Synergistic antimicrobial compositions and methods of inhibiting biofilm formation |
| WO2005018701A1 (en) * | 2003-08-25 | 2005-03-03 | Kane Biotech Inc. | Synergistic antimicrobial compositions and methods of inhibiting biofilm formation |
| WO2005063278A1 (en) | 2003-12-30 | 2005-07-14 | Bioactive Polymers Ab | Surface protection of exposed biological tissues |
| ATE381945T1 (de) | 2004-03-12 | 2008-01-15 | Intercell Ag | Verfahren zur solubilisierung von peptid- mischungen |
| PL1778720T3 (pl) | 2004-08-18 | 2011-03-31 | Novabiotics Ltd | Antybakteryjne peptydy zawierające wzór zawierający argininę i/lub lizynę |
| EP1891097B1 (en) * | 2005-06-06 | 2016-11-16 | Adenium Biotech ApS | Polypeptides having antimicrobial activity and polynucleotides encoding same |
| US20080139450A1 (en) | 2005-07-01 | 2008-06-12 | Srinivasa Madhyastha | Antimicrobial Compositions and Uses Thereof |
| US20070190110A1 (en) * | 2006-02-10 | 2007-08-16 | Pameijer Cornelis H | Agents and devices for providing blood clotting functions to wounds |
| CA2671461C (en) * | 2006-12-01 | 2014-01-28 | The Regents Of The University Of California | Vesicles of self-assembling block copolymers and methods for making and using the same |
| CN101720237A (zh) | 2007-06-25 | 2010-06-02 | 利波佩普蒂德有限公司 | 新型医用产品 |
| WO2009032605A2 (en) * | 2007-08-27 | 2009-03-12 | Massachusetts Institute Of Technology | Bi-functional polymer-attached inhibitors of influenza virus |
| JP5467366B2 (ja) | 2008-03-10 | 2014-04-09 | 国立大学法人 東京大学 | 非荷電性親水性ブロック及び側鎖の一部に疎水性基が導入されたカチオン性のポリアミノ酸ブロックを含んでなる共重合体、その使用 |
| KR20110031168A (ko) * | 2008-06-19 | 2011-03-24 | 니뽄 신야쿠 가부시키가이샤 | 약물 담체 |
| GB0818074D0 (en) * | 2008-10-02 | 2008-11-05 | Lytix Biopharma As | Treatment of biofilms |
| CN102256613B (zh) * | 2008-10-20 | 2014-09-10 | 莫伊莱麦屈克斯公司 | 用于治疗或者预防粘连的多肽 |
| WO2010083589A1 (en) * | 2009-01-23 | 2010-07-29 | Kane Biotech Inc. | Biofilm-removing antimicrobial compositions and uses thereof |
| GB0905451D0 (en) * | 2009-03-31 | 2009-05-13 | Novabiotics Ltd | Biofilms |
| SG184836A1 (en) * | 2010-04-27 | 2012-11-29 | Lysando Ag | Method of reducing biofilms |
| SG188281A1 (en) * | 2010-08-23 | 2013-04-30 | Univ California | Compositions and uses of materials with high antimicrobial activity and low toxicity |
| JP5613779B2 (ja) * | 2011-01-19 | 2014-10-29 | 株式会社メニコン | コンタクトレンズ用液剤 |
| US9781949B2 (en) * | 2011-03-31 | 2017-10-10 | The University Of Massachusetts | Antimicrobial delivery systems, methods of manufacture, and methods of use thereof |
| ES2991989T3 (es) | 2012-03-23 | 2024-12-05 | Macro Biologics Inc | Composiciones y usos de materiales antimicrobianos con propiedades compatibles con tejidos |
| DE102014101663A1 (de) | 2014-02-11 | 2015-08-13 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Synthetische artifizielle Peptide mit antimikrobieller Wirkung |
| WO2016044683A1 (en) | 2014-09-19 | 2016-03-24 | Tensive Controls, Inc. | Anti-microbial peptides |
| EP3215126A1 (en) | 2014-10-30 | 2017-09-13 | Biomet Manufacturing, LLC | Methods of preventing surgical site infections |
| JP2016113373A (ja) | 2014-12-11 | 2016-06-23 | エスポ化学株式会社 | 抗菌性、抗ウイルス性を有する水溶性組成物 |
| US11285189B2 (en) | 2017-04-06 | 2022-03-29 | Amicrobe, Inc. | Compositions and uses of locally-applied antimicrobial synthetic cationic polypeptide(s) with enhanced performance and safety |
| US20210007999A1 (en) * | 2018-03-02 | 2021-01-14 | January Therapeutics, Inc. | Nanoparticle compositions |
-
2013
- 2013-03-15 ES ES13764971T patent/ES2991989T3/es active Active
- 2013-03-15 RU RU2014137827A patent/RU2680959C2/ru active
- 2013-03-15 US US14/385,752 patent/US9446090B2/en active Active
- 2013-03-15 AU AU2013235336A patent/AU2013235336B2/en active Active
- 2013-03-15 PL PL13764971.1T patent/PL2827841T3/pl unknown
- 2013-03-15 KR KR1020147029534A patent/KR102141254B1/ko active Active
- 2013-03-15 IN IN8299DEN2014 patent/IN2014DN08299A/en unknown
- 2013-03-15 HU HUE13764971A patent/HUE069626T2/hu unknown
- 2013-03-15 WO PCT/US2013/032535 patent/WO2013142374A1/en not_active Ceased
- 2013-03-15 BR BR112014023068-4A patent/BR112014023068B1/pt active IP Right Grant
- 2013-03-15 CN CN201380016185.9A patent/CN104582688A/zh active Pending
- 2013-03-15 KR KR1020207022133A patent/KR102266659B1/ko active Active
- 2013-03-15 EP EP24200847.2A patent/EP4516101A3/en active Pending
- 2013-03-15 MX MX2014011237A patent/MX344635B/es active IP Right Grant
- 2013-03-15 MX MX2016017289A patent/MX378738B/es unknown
- 2013-03-15 JP JP2015503344A patent/JP6224069B2/ja active Active
- 2013-03-15 EP EP13764971.1A patent/EP2827841B8/en active Active
- 2013-03-15 CA CA2867903A patent/CA2867903C/en active Active
-
2014
- 2014-10-01 ZA ZA2014/07121A patent/ZA201407121B/en unknown
-
2016
- 2016-08-18 US US15/240,197 patent/US11298401B2/en active Active
- 2016-11-14 AU AU2016259282A patent/AU2016259282B2/en active Active
-
2017
- 2017-10-04 JP JP2017194019A patent/JP2018020175A/ja active Pending
-
2019
- 2019-09-12 JP JP2019166236A patent/JP7255787B2/ja active Active
-
2020
- 2020-11-04 JP JP2020184556A patent/JP2021020964A/ja active Pending
-
2022
- 2022-03-01 US US17/684,267 patent/US12016898B2/en active Active
- 2022-11-04 JP JP2022176900A patent/JP2023011850A/ja active Pending
-
2024
- 2024-06-20 US US18/749,392 patent/US20250121027A1/en active Pending
-
2025
- 2025-02-07 JP JP2025019121A patent/JP2025065375A/ja active Pending
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