|
US20120121515A1
(en)
|
2009-03-13 |
2012-05-17 |
Lenny Dang |
Methods and compositions for cell-proliferation-related disorders
|
|
TWI598337B
(zh)
|
2009-06-29 |
2017-09-11 |
阿吉歐斯製藥公司 |
治療化合物及組成物
|
|
WO2011050210A1
(en)
|
2009-10-21 |
2011-04-28 |
Agios Pharmaceuticals, Inc. |
Methods and compositions for cell-proliferation-related disorders
|
|
SMT202400081T1
(it)
|
2011-05-03 |
2024-03-13 |
Agios Pharmaceuticals Inc |
Attivatori della piruvato chinasi per uso in terapia
|
|
CN102827170A
(zh)
|
2011-06-17 |
2012-12-19 |
安吉奥斯医药品有限公司 |
治疗活性组合物和它们的使用方法
|
|
CN102827073A
(zh)
|
2011-06-17 |
2012-12-19 |
安吉奥斯医药品有限公司 |
治疗活性组合物和它们的使用方法
|
|
PE20142098A1
(es)
|
2012-01-06 |
2015-01-08 |
Agios Pharmaceuticals Inc |
Compuestos terapeuticamente activos y sus metodos de uso
|
|
US9474779B2
(en)
|
2012-01-19 |
2016-10-25 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compositions and their methods of use
|
|
EP2906212A4
(en)
|
2012-10-15 |
2016-06-08 |
Agios Pharmaceuticals Inc |
THERAPEUTIC COMPOUNDS AND COMPOSITIONS
|
|
CN105593215B
(zh)
|
2013-07-11 |
2019-01-15 |
安吉奥斯医药品有限公司 |
用于治疗癌症的作为idh2突变体抑制剂的2,4-或4,6-二氨基嘧啶化合物
|
|
WO2015003360A2
(en)
|
2013-07-11 |
2015-01-15 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compounds and their methods of use
|
|
AU2014287122B9
(en)
|
2013-07-11 |
2018-11-01 |
Les Laboratoires Servier |
N,6-bis(aryl or heteroaryl)-1,3,5-triazine-2,4-diamine compounds as IDH2 mutants inhibitors for the treatment of cancer
|
|
WO2015003355A2
(en)
|
2013-07-11 |
2015-01-15 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compounds and their methods of use
|
|
WO2015010297A1
(en)
*
|
2013-07-25 |
2015-01-29 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compounds and their methods of use
|
|
KR101861869B1
(ko)
*
|
2013-09-10 |
2018-05-28 |
경희대학교 산학협력단 |
신규한 비스-아미드 유도체 및 이의 용도
|
|
CN103694142A
(zh)
*
|
2013-11-28 |
2014-04-02 |
浙江科技学院 |
4-N-Boc-氨基环己酮的制备方法
|
|
NZ723859A
(en)
|
2014-03-14 |
2023-01-27 |
Servier Lab |
Pharmaceutical compositions of therapeutically active compounds and their uses
|
|
SG11201608303QA
(en)
|
2014-04-04 |
2016-11-29 |
Del Mar Pharmaceuticals |
Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer
|
|
BR112017006425B8
(pt)
|
2014-10-01 |
2023-05-16 |
Daiichi Sankyo Co Ltd |
Compostos derivados de isoxazol, seus usos, inibidores de isocitrato desidrogenase 1 mutante e da produção de d-2 hidroxiglutamato, agente antitumoral e composição farmacêutica compreendendo os mesmos
|
|
WO2016062677A1
(en)
*
|
2014-10-23 |
2016-04-28 |
Bayer Pharma Aktiengesellschaft |
Benzimidazol-2-amines as midh1 inhibitors
|
|
US10086000B2
(en)
|
2014-12-05 |
2018-10-02 |
Merck Sharp & Dohme Corp. |
Tricyclic compounds as inhibitors of mutant IDH enzymes
|
|
CA2989111C
(en)
|
2015-06-11 |
2023-10-03 |
Agios Pharmaceuticals, Inc. |
Methods of using pyruvate kinase activators
|
|
FI3362065T3
(fi)
|
2015-10-15 |
2024-06-19 |
Servier Lab |
Ivosidenibiä, sytarabiinia ja daunorubisiinia tai idarubisiinia käsittävä yhdistelmähoito akuutin myelooisen leukemian hoitamiseksi
|
|
KR102699521B1
(ko)
|
2015-10-15 |
2024-08-26 |
르 라보레또레 쎄르비에르 |
악성 종양의 치료를 위한 조합물 요법
|
|
WO2017140758A1
(en)
|
2016-02-19 |
2017-08-24 |
Debiopharm International S.A. |
Derivatives of 2-amino-4-(2-oxazolidinon-3-yl)-pyrimidine fused with a five-membered heteroaromatic ring in 5,6-position which are useful for the treatment of various cancers
|
|
TW201736341A
(zh)
|
2016-03-22 |
2017-10-16 |
Chia Tai Tianqing Pharmaceutical Group Co Ltd |
丙啶磺醯胺類化合物及其使用方法
|
|
ES2842448T3
(es)
|
2016-03-22 |
2021-07-14 |
Lianyungang Runzhong Pharmaceutical Co Ltd |
Compuesto de sultama y método de aplicación del mismo
|
|
MX379576B
(es)
*
|
2017-02-28 |
2025-03-11 |
Chia Tai Tianqing Pharmaceutical Group Co Ltd |
Derivados de azetidina
|
|
KR102707847B1
(ko)
*
|
2017-09-22 |
2024-09-23 |
치아타이 티안큉 파마수티컬 그룹 주식회사 |
결정형 설파마이드 화합물
|
|
CN107827880B
(zh)
*
|
2017-10-17 |
2020-05-22 |
浙江工业大学上虞研究院有限公司 |
一种含咪唑和1,3,4-噁二唑结构的甲腈类化合物及其制备方法和应用
|
|
US11013734B2
(en)
|
2018-05-16 |
2021-05-25 |
Forma Therapeutics, Inc. |
Treating patients harboring an isocitrate dehydrogenase-1 (IDH-1) mutation
|
|
US11013733B2
(en)
|
2018-05-16 |
2021-05-25 |
Forma Therapeutics, Inc. |
Inhibiting mutant isocitrate dehydrogenase 1 (mlDH-1)
|
|
WO2019222551A1
(en)
|
2018-05-16 |
2019-11-21 |
Forma Therapeutics, Inc. |
Solid forms of ((s)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2-carbonitrile
|
|
US11311527B2
(en)
|
2018-05-16 |
2022-04-26 |
Forma Therapeutics, Inc. |
Inhibiting mutant isocitrate dehydrogenase 1 (mIDH-1)
|
|
US20210196701A1
(en)
|
2018-05-16 |
2021-07-01 |
Forma Therapeutics, Inc. |
Inhibiting mutant idh-1
|
|
US10980788B2
(en)
|
2018-06-08 |
2021-04-20 |
Agios Pharmaceuticals, Inc. |
Therapy for treating malignancies
|
|
CN109535025B
(zh)
*
|
2018-12-18 |
2022-09-09 |
尚科生物医药（上海）有限公司 |
一种艾伏尼布中间体3,3-二氟环丁胺盐酸盐的制备方法
|
|
WO2020127887A1
(en)
*
|
2018-12-21 |
2020-06-25 |
Sandoz Ag |
Process for the preparation of an intermediate product of ivosidenib
|
|
US12358886B2
(en)
|
2019-08-09 |
2025-07-15 |
Artios Pharma Limited |
Heterocyclic compounds for use in the treatment of cancer
|
|
TW202120486A
(zh)
*
|
2019-08-09 |
2021-06-01 |
英商阿帝歐斯製藥有限公司 |
新穎化合物
|
|
WO2022026565A1
(en)
*
|
2020-07-29 |
2022-02-03 |
Ideaya Biosciences, Inc. |
Cyclized acetamido derivatives as dna polymerase theta inhibitors
|
|
EP4204087A1
(en)
*
|
2020-08-26 |
2023-07-05 |
Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft |
Inhibitors of no production
|
|
WO2023241322A1
(en)
*
|
2022-06-16 |
2023-12-21 |
Danatlas Pharmaceuticals Co., Ltd. |
Heterocyclic derivatives, compositions and uses thereof
|
|
WO2024153143A1
(zh)
*
|
2023-01-18 |
2024-07-25 |
中国药科大学 |
含氮并环类化合物及其应用
|
|
WO2025171103A1
(en)
*
|
2024-02-08 |
2025-08-14 |
Luxvitae Therapeutics Inc. |
Amino acid derivatives and method of making the same
|