JP2015510436A - 生体指標をモニターするための組成物および方法 - Google Patents

生体指標をモニターするための組成物および方法 Download PDF

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Publication number
JP2015510436A
JP2015510436A JP2014557798A JP2014557798A JP2015510436A JP 2015510436 A JP2015510436 A JP 2015510436A JP 2014557798 A JP2014557798 A JP 2014557798A JP 2014557798 A JP2014557798 A JP 2014557798A JP 2015510436 A JP2015510436 A JP 2015510436A
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Prior art keywords
hematocrit
fluorescent
marker
fluorescence
emission
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JP2014557798A
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Japanese (ja)
Inventor
メイアー ダニエル
メイアー ダニエル
モリトリス ブルース
モリトリス ブルース
シェリダン エリン
シェリダン エリン
サンドバル ルーベン
サンドバル ルーベン
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ファーマコフォトニクス,インコーポレイティド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0088Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for oral or dental tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14535Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring haematocrit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/20Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/201Assessing renal or kidney functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6814Head
    • A61B5/682Mouth, e.g., oral cavity; tongue; Lips; Teeth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dentistry (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Urology & Nephrology (AREA)
  • Audiology, Speech & Language Pathology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Physiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2014557798A 2012-02-17 2013-02-15 生体指標をモニターするための組成物および方法 Pending JP2015510436A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261600182P 2012-02-17 2012-02-17
US61/600,182 2012-02-17
PCT/US2013/026277 WO2013123285A1 (en) 2012-02-17 2013-02-15 Compositions and methods for monitoring biometric indicators

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018036525A Division JP2018102959A (ja) 2012-02-17 2018-03-01 生体指標をモニターするための組成物および方法

Publications (1)

Publication Number Publication Date
JP2015510436A true JP2015510436A (ja) 2015-04-09

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Family Applications (3)

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JP2014557798A Pending JP2015510436A (ja) 2012-02-17 2013-02-15 生体指標をモニターするための組成物および方法
JP2018036525A Pending JP2018102959A (ja) 2012-02-17 2018-03-01 生体指標をモニターするための組成物および方法
JP2020093506A Pending JP2020163170A (ja) 2012-02-17 2020-05-28 生体指標をモニターするための組成物および方法

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JP2018036525A Pending JP2018102959A (ja) 2012-02-17 2018-03-01 生体指標をモニターするための組成物および方法
JP2020093506A Pending JP2020163170A (ja) 2012-02-17 2020-05-28 生体指標をモニターするための組成物および方法

Country Status (8)

Country Link
US (2) US20140369936A1 (cg-RX-API-DMAC7.html)
EP (2) EP3207873A1 (cg-RX-API-DMAC7.html)
JP (3) JP2015510436A (cg-RX-API-DMAC7.html)
CN (2) CN104244826A (cg-RX-API-DMAC7.html)
AU (1) AU2013221451A1 (cg-RX-API-DMAC7.html)
CA (1) CA2863788A1 (cg-RX-API-DMAC7.html)
IN (1) IN2014DN06772A (cg-RX-API-DMAC7.html)
WO (1) WO2013123285A1 (cg-RX-API-DMAC7.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022504413A (ja) * 2018-10-05 2022-01-13 ファーマコフォトニクス,インコーポレイティド,ディー/ビー/エー ファスト バイオメディカル 間隙体積を決定するための方法及び装置
JP2023061990A (ja) * 2018-01-16 2023-05-02 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ 腎機能を決定するための方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013221451A1 (en) * 2012-02-17 2014-08-21 Pharmacophotonics, Inc. Compositions and methods for monitoring biometric indicators
WO2015061680A1 (en) 2013-10-24 2015-04-30 Pharmacophotonics, Inc. D/B/A Fast Biomedical Compositions and methods for optimizing the detection of fluorescent signals from biomarkers
US20180180622A1 (en) * 2015-06-24 2018-06-28 Pharmacophotonics, Inc. D/B/A Fast Biomedical Method and apparatus for determining biometric indicators using multiple fluorescent markers
KR102306048B1 (ko) * 2017-01-30 2021-09-29 메디비콘 아이엔씨. 확산 반사 보정을 갖는 형광 추적제의 비침습 모니터링 방법
HUE071082T2 (hu) * 2018-06-08 2025-08-28 Revvity Health Sciences Inc Többspektrális elemzõ rendszerek kalibrálása
US11946865B2 (en) * 2018-06-28 2024-04-02 Becton, Dickinson And Company Systems and methods for normalizing signals in blood culture measurement systems
WO2020264295A1 (en) * 2019-06-28 2020-12-30 Procisedx Inc. Methods for accommodating for sample matrix effects in light measurement assays

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11192207A (ja) * 1997-11-07 1999-07-21 Matsushita Electric Ind Co Ltd ビデオスコープおよび携帯収納ケース
JP2001008893A (ja) * 1999-06-29 2001-01-16 Toshiyuki Abe 口腔テレビカメラのプローブ
JP2002515276A (ja) * 1998-05-16 2002-05-28 ヘルムート・フント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 歯垢を位置決定するための蛍光手段を備えた歯ブラシ
WO2003024385A1 (fr) * 2001-09-12 2003-03-27 Terumo Kabushiki Kaisha Reservoir de medicament et dispositif d'injection de medicament integrant ledit reservoir
JP2004517041A (ja) * 2000-07-19 2004-06-10 ザ ジェネラル ホスピタル コーポレーション 有機官能基の実時間測定のための蛍光剤
JP2007175502A (ja) * 2005-12-27 2007-07-12 Intuitive Surgical Inc 外科手術用ロボットのための連接式で交換可能な内視鏡
JP2008538316A (ja) * 2005-04-19 2008-10-23 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーション 腎臓機能分析のための方法及び装置
WO2010127136A2 (en) * 2009-04-30 2010-11-04 Pharmacophotonics, Inc. Measurement of body fluid volumes
JP2010538785A (ja) * 2007-09-19 2010-12-16 キングス カレッジ ロンドン 撮像装置および方法
JP2011521899A (ja) * 2008-04-18 2011-07-28 ファーマコフォトニクス,インコーポレイティド 腎機能の分析方法及び装置
WO2012005891A1 (en) * 2010-06-29 2012-01-12 Mcneil-Ppc, Inc. Method for cleaning the oral cavity

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5341805A (en) * 1993-04-06 1994-08-30 Cedars-Sinai Medical Center Glucose fluorescence monitor and method
EP1620002B1 (en) * 2003-04-24 2012-01-04 The Board Of Regents, The University Of Texas System Noninvasive blood analysis by optical probing of the veins under the tongue
DE102004024494B4 (de) * 2004-05-16 2019-10-17 Dürr Dental SE Medizinische Kamera
US7796243B2 (en) * 2004-06-09 2010-09-14 National Research Council Of Canada Detection and monitoring of changes in mineralized tissues or calcified deposits by optical coherence tomography and Raman spectroscopy
US7440788B2 (en) * 2004-08-26 2008-10-21 Kelvyn Enterprises, Inc. Oral health measurement clamping probe, system, and method
US7386333B1 (en) * 2005-04-29 2008-06-10 Henryk Birecki Test subject monitoring device
US20100268090A1 (en) * 2007-11-06 2010-10-21 Rubinstein Eduardo H Measurement of hematocrit and cardiac output from optical transmission and reflection changes
US9746471B2 (en) * 2008-01-25 2017-08-29 Multivir Inc. P53 biomarkers
US8591865B2 (en) 2008-04-18 2013-11-26 Pharmacophotonics, Inc. Renal function analysis method and apparatus
WO2010009335A1 (en) * 2008-07-17 2010-01-21 Micell Technologies, Inc. Drug delivery medical device
GB201011913D0 (en) * 2010-07-15 2010-09-01 Lux Innovate Ltd Detecting device
AU2013221451A1 (en) * 2012-02-17 2014-08-21 Pharmacophotonics, Inc. Compositions and methods for monitoring biometric indicators

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11192207A (ja) * 1997-11-07 1999-07-21 Matsushita Electric Ind Co Ltd ビデオスコープおよび携帯収納ケース
JP2002515276A (ja) * 1998-05-16 2002-05-28 ヘルムート・フント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 歯垢を位置決定するための蛍光手段を備えた歯ブラシ
JP2001008893A (ja) * 1999-06-29 2001-01-16 Toshiyuki Abe 口腔テレビカメラのプローブ
JP2004517041A (ja) * 2000-07-19 2004-06-10 ザ ジェネラル ホスピタル コーポレーション 有機官能基の実時間測定のための蛍光剤
WO2003024385A1 (fr) * 2001-09-12 2003-03-27 Terumo Kabushiki Kaisha Reservoir de medicament et dispositif d'injection de medicament integrant ledit reservoir
JP2008538316A (ja) * 2005-04-19 2008-10-23 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーション 腎臓機能分析のための方法及び装置
JP2007175502A (ja) * 2005-12-27 2007-07-12 Intuitive Surgical Inc 外科手術用ロボットのための連接式で交換可能な内視鏡
JP2010538785A (ja) * 2007-09-19 2010-12-16 キングス カレッジ ロンドン 撮像装置および方法
JP2011521899A (ja) * 2008-04-18 2011-07-28 ファーマコフォトニクス,インコーポレイティド 腎機能の分析方法及び装置
WO2010127136A2 (en) * 2009-04-30 2010-11-04 Pharmacophotonics, Inc. Measurement of body fluid volumes
WO2012005891A1 (en) * 2010-06-29 2012-01-12 Mcneil-Ppc, Inc. Method for cleaning the oral cavity

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023061990A (ja) * 2018-01-16 2023-05-02 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ 腎機能を決定するための方法
JP7547522B2 (ja) 2018-01-16 2024-09-09 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ 腎機能を決定するための方法
JP2022504413A (ja) * 2018-10-05 2022-01-13 ファーマコフォトニクス,インコーポレイティド,ディー/ビー/エー ファスト バイオメディカル 間隙体積を決定するための方法及び装置

Also Published As

Publication number Publication date
EP3207873A1 (en) 2017-08-23
JP2018102959A (ja) 2018-07-05
CN108261183A (zh) 2018-07-10
EP2814393B1 (en) 2017-04-05
AU2013221451A1 (en) 2014-08-21
US20180147302A1 (en) 2018-05-31
JP2020163170A (ja) 2020-10-08
EP2814393A1 (en) 2014-12-24
US20180256755A9 (en) 2018-09-13
US20140369936A1 (en) 2014-12-18
CA2863788A1 (en) 2013-08-22
WO2013123285A1 (en) 2013-08-22
EP2814393A4 (en) 2015-10-14
CN104244826A (zh) 2014-12-24
IN2014DN06772A (cg-RX-API-DMAC7.html) 2015-05-22

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