JP2015509368A5 - - Google Patents
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- Publication number
- JP2015509368A5 JP2015509368A5 JP2014558920A JP2014558920A JP2015509368A5 JP 2015509368 A5 JP2015509368 A5 JP 2015509368A5 JP 2014558920 A JP2014558920 A JP 2014558920A JP 2014558920 A JP2014558920 A JP 2014558920A JP 2015509368 A5 JP2015509368 A5 JP 2015509368A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261603622P | 2012-02-27 | 2012-02-27 | |
| US61/603,622 | 2012-02-27 | ||
| PCT/US2013/027580 WO2013130381A1 (en) | 2012-02-27 | 2013-02-25 | Cx3cr1-binding polypeptides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015509368A JP2015509368A (ja) | 2015-03-30 |
| JP2015509368A5 true JP2015509368A5 (OSRAM) | 2015-05-07 |
| JP6101715B2 JP6101715B2 (ja) | 2017-03-22 |
Family
ID=47884535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014558920A Active JP6101715B2 (ja) | 2012-02-27 | 2013-02-25 | Ｃｘ３ｃｒ１結合ポリペプチド |
Country Status (27)
| Country | Link |
|---|---|
| US (6) | US9035029B2 (OSRAM) |
| EP (2) | EP4050027A3 (OSRAM) |
| JP (1) | JP6101715B2 (OSRAM) |
| KR (1) | KR102008136B1 (OSRAM) |
| CN (3) | CN115925938A (OSRAM) |
| AP (1) | AP2014007791A0 (OSRAM) |
| AR (1) | AR090158A1 (OSRAM) |
| AU (1) | AU2013226340B2 (OSRAM) |
| CA (1) | CA2862182A1 (OSRAM) |
| CL (1) | CL2014002072A1 (OSRAM) |
| EA (1) | EA028183B1 (OSRAM) |
| EC (1) | ECSP14020402A (OSRAM) |
| GE (1) | GEP201706773B (OSRAM) |
| IL (3) | IL291571B2 (OSRAM) |
| IN (1) | IN2014DN05756A (OSRAM) |
| MD (1) | MD4548C1 (OSRAM) |
| MX (1) | MX349192B (OSRAM) |
| NZ (1) | NZ627260A (OSRAM) |
| PE (1) | PE20141859A1 (OSRAM) |
| PH (2) | PH12021553014A1 (OSRAM) |
| SG (1) | SG11201405283SA (OSRAM) |
| TN (1) | TN2014000360A1 (OSRAM) |
| TW (1) | TWI598361B (OSRAM) |
| UA (1) | UA115781C2 (OSRAM) |
| UY (1) | UY34644A (OSRAM) |
| WO (1) | WO2013130381A1 (OSRAM) |
| ZA (3) | ZA201405021B (OSRAM) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9101674B2 (en) | 2010-03-29 | 2015-08-11 | Vib Vzw | Targeting and in vivo imaging of tumor-associated macrophages |
| US9556273B2 (en) | 2010-03-29 | 2017-01-31 | Vib Vzw | Anti-macrophage mannose receptor single variable domains for targeting and in vivo imaging of tumor-associated macrophages |
| UA115781C2 (uk) | 2012-02-27 | 2017-12-26 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | Cx3cr1-зв'язуючий поліпептид |
| US9637542B2 (en) * | 2013-08-21 | 2017-05-02 | Boehringer Ingelheim International Gmbh | CX3CR1-targeting imaging agents and their use in the diagnosis and treatment of disease |
| RU2609627C2 (ru) * | 2014-09-26 | 2017-02-02 | Закрытое Акционерное Общество "Биокад" | Высокоаффинные и агрегационно стабильные антитела на основе вариабельных доменов vl и производного vhh |
| CA2992298A1 (en) | 2015-07-23 | 2017-01-26 | Inhibrx Lp | Multivalent and multispecific gitr-binding fusion proteins |
| SG11201805422WA (en) * | 2016-01-11 | 2018-07-30 | Inhibrx Inc | Multivalent and multispecific ox40-binding fusion proteins |
| US12128102B2 (en) | 2016-03-08 | 2024-10-29 | Takeda Pharmaceutical Company Limited | Constrained conditionally activated binding proteins |
| TW201808990A (zh) * | 2016-03-08 | 2018-03-16 | 馬弗瑞克療法公司 | 可誘導性結合蛋白和使用方法 |
| EA201991269A1 (ru) * | 2016-11-29 | 2019-10-31 | Профилактический агент, агент, подавляющий начало заболевания, или терапевтический агент для прогрессирующих иммунных демиелинизирующих заболеваний | |
| WO2018134815A2 (en) * | 2017-01-17 | 2018-07-26 | Yeda Research And Development Co. Ltd. | Methods of treating neurodegenerative diseases by inducing disease-associated microglia (dam) cells |
| MX2020002667A (es) | 2017-09-08 | 2020-08-03 | Maverick Therapeutics Inc | Proteinas de unión condicionalmente activadas restringidas. |
| KR20210044243A (ko) | 2018-08-13 | 2021-04-22 | 인히브릭스, 인크. | Ox40 결합 폴리펩티드 및 이의 용도 |
| CN120484127A (zh) | 2019-03-05 | 2025-08-15 | 武田药品工业有限公司 | 受约束的条件性活化的结合蛋白 |
| CN110675421B (zh) * | 2019-08-30 | 2022-03-15 | 电子科技大学 | 基于少量标注框的深度图像协同分割方法 |
| EP4157883A4 (en) * | 2020-06-02 | 2024-12-04 | Children's Medical Center Corporation | NANOBODY CONJUGATES (VHH) AND THEIR USES |
| WO2022165434A2 (en) * | 2021-02-01 | 2022-08-04 | The General Hospital Corporation | Fc-enhanced antibodies for prevention and treatment of ebola virus infection |
| TW202246334A (zh) * | 2021-02-02 | 2022-12-01 | 美商美國禮來大藥廠 | Gitr拮抗劑及其使用方法 |
| KR20250040019A (ko) | 2022-07-18 | 2025-03-21 | 아블린쓰 | Cx3cr1 결합 화합물, 이의 용도, 및 관련 방법 |
| KR20250126016A (ko) | 2022-12-22 | 2025-08-22 | 치오메 바이오사이언스 가부시키가이샤 | 항인간 cx3cr1 항체 |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0656946B2 (en) | 1992-08-21 | 2010-03-31 | Vrije Universiteit Brussel | Immunoglobulins devoid of light chains |
| EP0739981A1 (en) | 1995-04-25 | 1996-10-30 | Vrije Universiteit Brussel | Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes |
| US6329516B1 (en) | 1997-04-28 | 2001-12-11 | Fmc Corporation | Lepidopteran GABA-gated chloride channels |
| AU2000273378A1 (en) | 2000-02-18 | 2001-08-27 | Millennium Pharmaceuticals, Inc. | Therapeutic methods that target fractalkine or cx3cr1 |
| CA2405550A1 (en) | 2000-04-12 | 2001-10-25 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US20020192212A1 (en) * | 2001-03-19 | 2002-12-19 | Toshio Imai | Uses of anti-CX3CR1 antibody, anti-fractalkine antibody and fractalkine |
| DE60237282D1 (de) | 2001-06-28 | 2010-09-23 | Domantis Ltd | Doppelspezifischer ligand und dessen verwendung |
| JP4123856B2 (ja) | 2001-07-31 | 2008-07-23 | 日油株式会社 | 生体関連物質の修飾剤およびポリオキシアルキレン誘導体の製造方法 |
| US20050069962A1 (en) | 2001-10-12 | 2005-03-31 | Archer Robert M | Antibody complexes and methods for immunolabeling |
| CA2484556A1 (en) | 2001-12-21 | 2003-07-24 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US20060160076A1 (en) | 2002-06-10 | 2006-07-20 | Meatabolex, Inc. | Methods of treating and diagnosing diabetes with cx3cr1 modulators |
| EP1558647B1 (en) | 2002-11-08 | 2015-06-10 | Ablynx N.V. | Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor |
| KR101025143B1 (ko) | 2002-12-31 | 2011-04-01 | 넥타르 테라퓨틱스 | 가수분해상으로 안정한 말레이미드－종결 중합체 |
| DK1639011T3 (da) | 2003-06-30 | 2009-02-16 | Domantis Ltd | Pegylerede enkelt-domæne antistoffer (dAb) |
| WO2005103684A2 (en) | 2004-04-20 | 2005-11-03 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with cx3c chemokine receptor 1 (cx3cr1) |
| BRPI0518151A2 (pt) | 2004-10-13 | 2009-06-16 | Ablynx Nv | polipetìdeos contra amiloide-beta, ácido nucléico que codifica tal polipetìdeo, composição compreendendo tal polipetìdeo, método para produzir um polipetìdeo e uso do mesmo |
| WO2006046739A1 (ja) | 2004-10-29 | 2006-05-04 | Eisai R & D Management Co., Ltd. | 炎症性疾患治療剤 |
| CN103254309B (zh) | 2005-05-18 | 2017-09-26 | 埃博灵克斯股份有限公司 | 针对肿瘤坏死因子α的改进的纳米体TM |
| US8642330B2 (en) | 2005-08-08 | 2014-02-04 | Onconon, Llc | Antibody compositions, methods for treating neoplastic disease and methods for regulating fertility |
| TWI323734B (en) * | 2005-08-19 | 2010-04-21 | Abbott Lab | Dual variable domain immunoglobulin and uses thereof |
| EP2057191A1 (en) | 2006-08-18 | 2009-05-13 | Ablynx N.V. | Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling |
| AU2007293614A1 (en) * | 2006-09-08 | 2008-03-13 | Ablynx N.V. | Serum albumin binding proteins with long half-lives |
| JP2010511397A (ja) | 2006-12-05 | 2010-04-15 | アブリンクス エン．ヴェー． | 血清タンパク質と結合可能なペプチド |
| CA2717015A1 (en) | 2008-03-05 | 2009-09-11 | Ablynx Nv | Novel antigen binding dimer-complexes, methods of making and uses thereof |
| WO2009127691A1 (en) | 2008-04-17 | 2009-10-22 | Ablynx N.V. | Peptides capable of binding to serum proteins and compounds, constructs and polypeptides comprising the same |
| DK2285408T3 (en) | 2008-06-05 | 2019-02-04 | Ablynx Nv | AMINO ACID SEQUENCES AGAINST COATING PROTEINS IN A VIRUS AND POLYPEPTIDES INCLUDING THESE FOR TREATMENT OF VIRUSAL DISEASES |
| WO2010070394A1 (en) | 2008-12-17 | 2010-06-24 | Universite Pierre Et Marie Curie-Paris Vi | Modulators of the cx3cr1 receptor and therapeutic uses thereof |
| US20110117113A1 (en) * | 2009-10-09 | 2011-05-19 | Gerald Beste | Immunoglobulin single variable domain directed against human cxcr4 and other cell associated proteins and methods to generate them |
| US20110085969A1 (en) | 2009-10-09 | 2011-04-14 | Rollo F David | Chelator-targeting ligand conjugates for cardiovascular imaging |
| EP2648754A4 (en) * | 2010-12-07 | 2016-02-24 | Philadelphia Health & Educatio | METHOD OF INHIBITING CANCER METASTASES |
| UA115781C2 (uk) | 2012-02-27 | 2017-12-26 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | Cx3cr1-зв'язуючий поліпептид |
| US9637542B2 (en) | 2013-08-21 | 2017-05-02 | Boehringer Ingelheim International Gmbh | CX3CR1-targeting imaging agents and their use in the diagnosis and treatment of disease |
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2013
- 2013-02-25 UA UAA201410430A patent/UA115781C2/uk unknown
- 2013-02-25 IL IL291571A patent/IL291571B2/en unknown
- 2013-02-25 PE PE2014001293A patent/PE20141859A1/es active IP Right Grant
- 2013-02-25 MD MDA20140104A patent/MD4548C1/ro not_active IP Right Cessation
- 2013-02-25 GE GEAP201313583A patent/GEP201706773B/en unknown
- 2013-02-25 JP JP2014558920A patent/JP6101715B2/ja active Active
- 2013-02-25 CN CN202210946091.2A patent/CN115925938A/zh active Pending
- 2013-02-25 SG SG11201405283SA patent/SG11201405283SA/en unknown
- 2013-02-25 KR KR1020147023938A patent/KR102008136B1/ko active Active
- 2013-02-25 AP AP2014007791A patent/AP2014007791A0/xx unknown
- 2013-02-25 PH PH1/2021/553014A patent/PH12021553014A1/en unknown
- 2013-02-25 CN CN201810147778.3A patent/CN108610421B/zh active Active
- 2013-02-25 NZ NZ627260A patent/NZ627260A/en unknown
- 2013-02-25 CA CA2862182A patent/CA2862182A1/en not_active Abandoned
- 2013-02-25 EA EA201400964A patent/EA028183B1/ru not_active IP Right Cessation
- 2013-02-25 EP EP22168124.0A patent/EP4050027A3/en active Pending
- 2013-02-25 MX MX2014009864A patent/MX349192B/es active IP Right Grant
- 2013-02-25 CN CN201380016996.9A patent/CN104245735B/zh active Active
- 2013-02-25 WO PCT/US2013/027580 patent/WO2013130381A1/en not_active Ceased
- 2013-02-25 AU AU2013226340A patent/AU2013226340B2/en active Active
- 2013-02-25 US US13/775,307 patent/US9035029B2/en active Active
- 2013-02-25 PH PH1/2014/501912A patent/PH12014501912B1/en unknown
- 2013-02-25 IN IN5756DEN2014 patent/IN2014DN05756A/en unknown
- 2013-02-25 IL IL311502A patent/IL311502A/en unknown
- 2013-02-25 EP EP13709641.8A patent/EP2820046B1/en active Active
- 2013-02-26 AR ARP130100585A patent/AR090158A1/es active IP Right Grant
- 2013-02-26 TW TW102106771A patent/TWI598361B/zh active
- 2013-02-27 UY UY0001034644A patent/UY34644A/es unknown
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2014
- 2014-07-09 ZA ZA2014/05021A patent/ZA201405021B/en unknown
- 2014-08-05 CL CL2014002072A patent/CL2014002072A1/es unknown
- 2014-08-07 IL IL234018A patent/IL234018B2/en unknown
- 2014-08-26 TN TNP2014000360A patent/TN2014000360A1/fr unknown
- 2014-09-25 EC ECIEPI201420402A patent/ECSP14020402A/es unknown
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2015
- 2015-04-09 US US14/682,131 patent/US9458235B2/en active Active
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2016
- 2016-08-22 US US15/242,639 patent/US9783612B2/en active Active
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2017
- 2017-09-29 US US15/720,792 patent/US10385134B2/en active Active
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2019
- 2019-07-09 US US16/505,773 patent/US11384151B2/en active Active
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2022
- 2022-06-09 US US17/836,473 patent/US12221487B2/en active Active
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2023
- 2023-09-19 ZA ZA2023/08845A patent/ZA202308845B/en unknown
- 2023-09-19 ZA ZA2023/08846A patent/ZA202308846B/en unknown