JP2015508655A - 組み合わせたヌクレアーゼ反応、連結反応、およびポリメラーゼ反応を用いて核酸配列、発現、またはコピー変化を相対的に定量するための方法 - Google Patents

組み合わせたヌクレアーゼ反応、連結反応、およびポリメラーゼ反応を用いて核酸配列、発現、またはコピー変化を相対的に定量するための方法 Download PDF

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JP2015508655A
JP2015508655A JP2014557776A JP2014557776A JP2015508655A JP 2015508655 A JP2015508655 A JP 2015508655A JP 2014557776 A JP2014557776 A JP 2014557776A JP 2014557776 A JP2014557776 A JP 2014557776A JP 2015508655 A JP2015508655 A JP 2015508655A
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oligonucleotide
oligonucleotide probe
primer
probe
target
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フランシス バラニー
フランシス バラニー
ユージーン スピア
ユージーン スピア
アライン ミール
アライン ミール
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Cornell University
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    • C12Q2521/00—Reaction characterised by the enzymatic activity
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    • C12Q2533/00—Reactions characterised by the enzymatic reaction principle used
    • C12Q2533/10—Reactions characterised by the enzymatic reaction principle used the purpose being to increase the length of an oligonucleotide strand
    • C12Q2533/107—Probe or oligonucleotide ligation

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JP2014557776A 2012-02-14 2013-02-14 組み合わせたヌクレアーゼ反応、連結反応、およびポリメラーゼ反応を用いて核酸配列、発現、またはコピー変化を相対的に定量するための方法 Pending JP2015508655A (ja)

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US201261598343P 2012-02-14 2012-02-14
US61/598,343 2012-02-14
US201261605057P 2012-02-29 2012-02-29
US61/605,057 2012-02-29
US201261644405P 2012-05-08 2012-05-08
US61/644,405 2012-05-08
PCT/US2013/026180 WO2013123220A1 (en) 2012-02-14 2013-02-14 Method for relative quantification of nucleic acid sequence, expression, or copy changes, using combined nuclease, ligation, and polymerase reactions

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JP2020072737A (ja) * 2014-04-21 2020-05-14 ナテラ， インコーポレイテッド 変異の検出および染色体分節の倍数性
WO2022138736A1 (ja) * 2020-12-25 2022-06-30 株式会社 TL Genomics シングルセルごとの特定の核酸のコピー数の検出方法

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