JP2015506174A - Ｃｇｒｐに特異的に結合する核酸 - Google Patents
Ｃｇｒｐに特異的に結合する核酸 Download PDFInfo
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- JP2015506174A JP2015506174A JP2014551569A JP2014551569A JP2015506174A JP 2015506174 A JP2015506174 A JP 2015506174A JP 2014551569 A JP2014551569 A JP 2014551569A JP 2014551569 A JP2014551569 A JP 2014551569A JP 2015506174 A JP2015506174 A JP 2015506174A
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| EPPCT/EP2012/000089 | 2012-01-10 | ||
| PCT/EP2012/000089 WO2012095303A1 (en) | 2011-01-10 | 2012-01-10 | Nucleic acid molecule having binding affinity to a target molecule and a method for generating the same |
| PCT/EP2013/000055 WO2013104539A1 (en) | 2012-01-10 | 2013-01-10 | Nucleic acids specifically binding cgrp |
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| JP2015506174A true JP2015506174A (ja) | 2015-03-02 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016155994A (ja) * | 2015-02-25 | 2016-09-01 | 学校法人 関西大学 | ゲル素材及びその製造方法 |
| CN108473560A (zh) * | 2015-09-24 | 2018-08-31 | 泰瓦制药国际有限公司 | 预防、治疗和减轻(持续性)创伤后头痛 |
| US11028160B2 (en) | 2016-09-23 | 2021-06-08 | Teva Pharmaceuticals International Gmbh | Treating refractory migraine |
| US11555064B2 (en) | 2014-03-21 | 2023-01-17 | Teva Pharmaceuticals International Gmbh | Treating headache comprising administering an antibody to calcitonin gene-related peptide |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2802660T (pt) | 2012-01-10 | 2020-04-21 | Aptarion Biotech Ag | Novos ácidos nucleicos que se ligam a c5a |
| ES2607639B1 (es) | 2015-09-30 | 2018-02-28 | Urquima, S.A | Sal de ácido maleico de un intermedio de silodosina |
| JP2022512969A (ja) * | 2018-11-12 | 2022-02-07 | アプタリオン バイオテック エージー | Ｃｘｃｌ８結合核酸 |
Citations (1)
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| US20060183700A1 (en) * | 2002-05-06 | 2006-08-17 | Noxxon Pharma Ag | Cgrp binding nucleic acids |
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| US6011020A (en) | 1990-06-11 | 2000-01-04 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligand complexes |
| US5840867A (en) | 1991-02-21 | 1998-11-24 | Gilead Sciences, Inc. | Aptamer analogs specific for biomolecules |
| US5582981A (en) | 1991-08-14 | 1996-12-10 | Gilead Sciences, Inc. | Method for identifying an oligonucleotide aptamer specific for a target |
| US6682886B1 (en) | 1994-04-28 | 2004-01-27 | Gilead Sciences, Inc. | Bivalent binding molecules of 7 transmembrane G protein-coupled receptors |
| JPH10504457A (ja) | 1994-08-16 | 1998-05-06 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | カルシトニンレセプター |
| EP1741780A3 (en) | 1995-06-02 | 2007-03-28 | Gilead Sciences, Inc. | High affinity oligonucleotide ligands to growth factors |
| US6395029B1 (en) | 1999-01-19 | 2002-05-28 | The Children's Hospital Of Philadelphia | Sustained delivery of polyionic bioactive agents |
| US6652886B2 (en) | 2001-02-16 | 2003-11-25 | Expression Genetics | Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents |
| RU2180311C1 (ru) | 2001-07-05 | 2002-03-10 | Мешалкин Георгий Алексеевич | Защитная пробка |
| DK1438321T5 (da) | 2001-10-26 | 2011-02-21 | Noxxon Pharma Ag | Modificeret L-nukleinsyre |
| EP1306382A1 (de) | 2001-10-26 | 2003-05-02 | Noxxon Pharma AG | Modifizierte L-Nukleinsäure |
| EP2138575B8 (en) | 2002-02-20 | 2013-07-24 | Mersana Therapeutics, Inc. | Conjugates comprising a biodegradable polymer and uses therefor |
| FI20051017A7 (fi) | 2003-04-13 | 2005-11-28 | Enzon Pharmaceutivals Inc | Polymeeriset oligonukleotidiaihiolääkkeet |
| GB0314472D0 (en) | 2003-06-20 | 2003-07-23 | Warwick Effect Polymers Ltd | Polymer |
| EP1713509A2 (de) | 2004-02-09 | 2006-10-25 | Noxxon Pharma AG | Verfahren zur herstellung von konjugaten aus polysacchariden und polynukleotiden |
| AU2005232371B2 (en) | 2004-03-23 | 2010-10-14 | Complex Biosystems Gmbh | Polymeric prodrug with a self-immolative linker |
| EP1807092B1 (en) | 2004-11-05 | 2016-09-07 | The Children's Hospital of Philadelphia | Biodegradable linkers for molecular therapies |
| WO2006117217A2 (de) * | 2005-05-04 | 2006-11-09 | Noxxon Pharma Ag | Neue verwendung von spiegelmeren |
| EP2063709A2 (en) | 2006-09-15 | 2009-06-03 | Enzon Pharmaceuticals, Inc. | Hindered ester-based biodegradable linkers for oligonucleotide delivery |
| EP2061901A2 (en) | 2006-10-31 | 2009-05-27 | Noxxon Pharma AG | Methods for detection of a single- or double-stranded nucleic acid molecule |
| EP2561079A1 (en) | 2010-04-21 | 2013-02-27 | Noxxon Pharma AG | Lipid binding nucleic acids |
| EP2663640B1 (en) * | 2011-01-10 | 2020-11-04 | APTARION biotech AG | Nucleic acid molecule having binding affinity to a target molecule and a method for generating the same |
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2013
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| US20060183700A1 (en) * | 2002-05-06 | 2006-08-17 | Noxxon Pharma Ag | Cgrp binding nucleic acids |
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| NUCLEIC ACIDS RESEARCH, vol. VOl.31, No.21 e130, JPN6016038921, 2003, pages 1 - 7 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11555064B2 (en) | 2014-03-21 | 2023-01-17 | Teva Pharmaceuticals International Gmbh | Treating headache comprising administering an antibody to calcitonin gene-related peptide |
| JP2016155994A (ja) * | 2015-02-25 | 2016-09-01 | 学校法人 関西大学 | ゲル素材及びその製造方法 |
| CN108473560A (zh) * | 2015-09-24 | 2018-08-31 | 泰瓦制药国际有限公司 | 预防、治疗和减轻(持续性)创伤后头痛 |
| JP2018532728A (ja) * | 2015-09-24 | 2018-11-08 | テバ・ファーマシューティカルズ・インターナショナル・ゲー・エム・ベー・ハー | （持続性）外傷後頭痛の予防、治療および低減 |
| JP2020002172A (ja) * | 2015-09-24 | 2020-01-09 | テバ・ファーマシューティカルズ・インターナショナル・ゲー・エム・ベー・ハー | （持続性）外傷後頭痛の予防、治療および低減 |
| US11028160B2 (en) | 2016-09-23 | 2021-06-08 | Teva Pharmaceuticals International Gmbh | Treating refractory migraine |
| US11028161B2 (en) | 2016-09-23 | 2021-06-08 | Teva Pharmaceuticals International Gmbh | Treating refractory migraine |
| US12139528B2 (en) | 2016-09-23 | 2024-11-12 | Teva Pharmaceuticals International Gmbh | Treating refractory migraine |
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| EP2802659A1 (en) | 2014-11-19 |
| WO2013104539A1 (en) | 2013-07-18 |
| SG11201403769YA (en) | 2014-07-30 |
| US20150031755A1 (en) | 2015-01-29 |
| IL233515A0 (en) | 2014-08-31 |
| US9163243B2 (en) | 2015-10-20 |
| CN104136612A (zh) | 2014-11-05 |
| MX2014008456A (es) | 2014-11-25 |
| KR20140111704A (ko) | 2014-09-19 |
| HK1198370A1 (en) | 2015-04-10 |
| CA2860809A1 (en) | 2013-07-18 |
| RU2014132706A (ru) | 2016-02-27 |
| AU2013209130A1 (en) | 2014-07-10 |
| BR112014016939A2 (pt) | 2019-09-24 |
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