JP2015504909A5 - - Google Patents
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- Publication number
- JP2015504909A5 JP2015504909A5 JP2014553715A JP2014553715A JP2015504909A5 JP 2015504909 A5 JP2015504909 A5 JP 2015504909A5 JP 2014553715 A JP2014553715 A JP 2014553715A JP 2014553715 A JP2014553715 A JP 2014553715A JP 2015504909 A5 JP2015504909 A5 JP 2015504909A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- sulfane
- galactopyranosyl
- bis
- benzopyran
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12152413.6 | 2012-01-25 | ||
| EP12152413.6A EP2620443A1 (en) | 2012-01-25 | 2012-01-25 | Novel galactoside inhibitors of galectins |
| PCT/EP2013/051339 WO2013110704A1 (en) | 2012-01-25 | 2013-01-24 | Novel galactoside inhibitors of galectins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015504909A JP2015504909A (ja) | 2015-02-16 |
| JP2015504909A5 true JP2015504909A5 (enExample) | 2016-03-10 |
| JP6158840B2 JP6158840B2 (ja) | 2017-07-05 |
Family
ID=47598867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014553715A Expired - Fee Related JP6158840B2 (ja) | 2012-01-25 | 2013-01-24 | ガレクチンのガラクトシド阻害剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9353141B2 (enExample) |
| EP (2) | EP2620443A1 (enExample) |
| JP (1) | JP6158840B2 (enExample) |
| CN (1) | CN104066743B (enExample) |
| CA (1) | CA2854986C (enExample) |
| ES (1) | ES2559857T3 (enExample) |
| IN (1) | IN2014DN05772A (enExample) |
| WO (1) | WO2013110704A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6586438B2 (en) | 1999-11-03 | 2003-07-01 | Bristol-Myers Squibb Co. | Antidiabetic formulation and method |
| KR20070089259A (ko) | 1999-11-03 | 2007-08-30 | 브리스톨-마이어스스퀴브컴파니 | 메트포르민 및 글리벤클아미드의 복합을 포함하는 제약조성물 |
| US9243021B2 (en) | 2012-10-31 | 2016-01-26 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| WO2014078655A1 (en) * | 2012-11-15 | 2014-05-22 | Tufts University | Methods, compositions and kits for treating, modulating, or preventing ocular angiogenesis or fibrosis in a subject using a galectin protein inhibitor |
| US9907814B2 (en) | 2012-12-20 | 2018-03-06 | Henry Ford Health System | Method for treating diastolic heart failure by inhibiting galectin-3 |
| US12390486B2 (en) | 2012-12-20 | 2025-08-19 | Henry Ford Health System | Method for treating diastolic heart failure by inhibiting galectin-3 |
| CN106536537B (zh) * | 2014-07-09 | 2020-07-07 | 卡雷多生物技术公司 | 半乳凝素的新型杂合半乳糖苷抑制剂 |
| EP3250581B1 (en) * | 2015-01-30 | 2021-01-20 | Galecto Biotech AB | Alpha-d-galactoside inhibitors of galectins |
| JP7086008B2 (ja) * | 2016-03-04 | 2022-06-17 | ガレクティン・サイエンシーズ・リミテッド・ライアビリティ・カンパニー | ガレクチンに関連する疾患を予防および処置するためのセレノガラクトシド化合物およびその使用 |
| CN109563120B (zh) * | 2016-07-12 | 2022-12-02 | 格莱克特生物技术公司 | 半乳糖凝集素的α-D-半乳糖苷抑制剂 |
| US10889610B2 (en) * | 2016-07-12 | 2021-01-12 | Galecto Biotech Ab | Alpha-D-galactoside inhibitors of galectins |
| AU2018265571B2 (en) | 2017-05-12 | 2022-09-29 | Galectin Sciences, Llc | Compounds for the prevention and treatment of diseases and the use thereof |
| EP3732186A1 (en) | 2017-12-29 | 2020-11-04 | GlycoMimetics, Inc. | Heterobifunctional inhibitors of e-selectin and galectin-3 |
| EP3813883A1 (en) * | 2018-06-29 | 2021-05-05 | Glykos Biomedical Oy | Conjugates |
| CA3122321A1 (en) | 2018-12-27 | 2020-07-02 | Glycomimetics, Inc. | Galectin-3 inhibiting c-glycosides |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
| ES2974680T3 (es) * | 2019-08-09 | 2024-07-01 | Idorsia Pharmaceuticals Ltd | Derivados de (2-acetamidil)tio-beta-D-galactopiranósidos |
| WO2021123506A1 (en) | 2019-12-18 | 2021-06-24 | Glykos Biomedical Oy | Stabile conjugate |
| CN116270672B (zh) * | 2023-02-27 | 2026-03-27 | 江苏科技大学 | β-D-硫代葡萄糖钠盐在制备缓解或治疗急性肾损伤的药物中的应用 |
| CZ2023132A3 (cs) | 2023-04-04 | 2024-10-16 | Ústav Chemických Procesů Av Čr, V. V. I. | Komplexy ruthenia pro inhibici galektinů, způsob jejich výroby a jejich použití |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0100172D0 (sv) | 2001-01-22 | 2001-01-22 | Ulf Nilsson | New inhibitors against galectins |
| SE0401301D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel 3-triazolyl-galactoside inhibitors of galectins |
| SE0401300D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel Galactoside Inhibitors of Galectins |
| EP2679595B1 (en) | 2008-05-16 | 2016-12-28 | Galecto Biotech AB | Di-(3-deoxy-3-1H-1,2,3-triazol-1-yl)-beta-D-galacto-pyranosyl)sulfane derivatives as galectin-3 inhibitors |
| US8703720B2 (en) | 2009-04-28 | 2014-04-22 | Galecto Biotech Ab | Galactoside inhibitors of galectins |
| EP2914269B1 (en) | 2012-10-31 | 2020-07-29 | Galecto Biotech AB | Galactoside inhibitor of galectin-3 and its use for treating pulmonary fibrosis |
-
2012
- 2012-01-25 EP EP12152413.6A patent/EP2620443A1/en not_active Withdrawn
-
2013
- 2013-01-24 CA CA2854986A patent/CA2854986C/en not_active Expired - Fee Related
- 2013-01-24 EP EP13700935.3A patent/EP2807176B1/en not_active Not-in-force
- 2013-01-24 JP JP2014553715A patent/JP6158840B2/ja not_active Expired - Fee Related
- 2013-01-24 CN CN201380006432.7A patent/CN104066743B/zh not_active Expired - Fee Related
- 2013-01-24 ES ES13700935.3T patent/ES2559857T3/es active Active
- 2013-01-24 WO PCT/EP2013/051339 patent/WO2013110704A1/en not_active Ceased
- 2013-01-24 US US14/364,169 patent/US9353141B2/en not_active Expired - Fee Related
- 2013-01-24 IN IN5772DEN2014 patent/IN2014DN05772A/en unknown
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