JP2015504909A5 - - Google Patents

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Publication number
JP2015504909A5
JP2015504909A5 JP2014553715A JP2014553715A JP2015504909A5 JP 2015504909 A5 JP2015504909 A5 JP 2015504909A5 JP 2014553715 A JP2014553715 A JP 2014553715A JP 2014553715 A JP2014553715 A JP 2014553715A JP 2015504909 A5 JP2015504909 A5 JP 2015504909A5
Authority
JP
Japan
Prior art keywords
methyl
sulfane
galactopyranosyl
bis
benzopyran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014553715A
Other languages
English (en)
Japanese (ja)
Other versions
JP6158840B2 (ja
JP2015504909A (ja
Filing date
Publication date
Priority claimed from EP12152413.6A external-priority patent/EP2620443A1/en
Application filed filed Critical
Publication of JP2015504909A publication Critical patent/JP2015504909A/ja
Publication of JP2015504909A5 publication Critical patent/JP2015504909A5/ja
Application granted granted Critical
Publication of JP6158840B2 publication Critical patent/JP6158840B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014553715A 2012-01-25 2013-01-24 ガレクチンのガラクトシド阻害剤 Expired - Fee Related JP6158840B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12152413.6 2012-01-25
EP12152413.6A EP2620443A1 (en) 2012-01-25 2012-01-25 Novel galactoside inhibitors of galectins
PCT/EP2013/051339 WO2013110704A1 (en) 2012-01-25 2013-01-24 Novel galactoside inhibitors of galectins

Publications (3)

Publication Number Publication Date
JP2015504909A JP2015504909A (ja) 2015-02-16
JP2015504909A5 true JP2015504909A5 (enExample) 2016-03-10
JP6158840B2 JP6158840B2 (ja) 2017-07-05

Family

ID=47598867

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014553715A Expired - Fee Related JP6158840B2 (ja) 2012-01-25 2013-01-24 ガレクチンのガラクトシド阻害剤

Country Status (8)

Country Link
US (1) US9353141B2 (enExample)
EP (2) EP2620443A1 (enExample)
JP (1) JP6158840B2 (enExample)
CN (1) CN104066743B (enExample)
CA (1) CA2854986C (enExample)
ES (1) ES2559857T3 (enExample)
IN (1) IN2014DN05772A (enExample)
WO (1) WO2013110704A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1229918B1 (en) 1999-11-03 2008-03-26 Bristol-Myers Squibb Company Pharmaceutical composition comprising a combination of metformin and glibenclamide
US6586438B2 (en) 1999-11-03 2003-07-01 Bristol-Myers Squibb Co. Antidiabetic formulation and method
US9243021B2 (en) 2012-10-31 2016-01-26 Galecto Biotech Ab Galactoside inhibitor of galectins
WO2014078655A1 (en) * 2012-11-15 2014-05-22 Tufts University Methods, compositions and kits for treating, modulating, or preventing ocular angiogenesis or fibrosis in a subject using a galectin protein inhibitor
US12390486B2 (en) 2012-12-20 2025-08-19 Henry Ford Health System Method for treating diastolic heart failure by inhibiting galectin-3
US9907814B2 (en) 2012-12-20 2018-03-06 Henry Ford Health System Method for treating diastolic heart failure by inhibiting galectin-3
JP6735680B2 (ja) * 2014-07-09 2020-08-05 ガレクト バイオテック エービー ガレクチンの新規ハイブリッドガラクトシド阻害剤
JP6904906B2 (ja) * 2015-01-30 2021-07-21 ガレクト・バイオテック・エイビイ ガレクチンの新規なガラクトシド阻害剤
CN109071585B (zh) * 2016-03-04 2022-08-16 卡莱克汀科学有限责任公司 预防和治疗半乳糖凝集素相关疾病的硒代半乳糖苷化合物及其用途
US10988502B2 (en) * 2016-07-12 2021-04-27 Galecto Biotech Ab Alpha-D-galactoside inhibitors of galectins
CA3025867A1 (en) * 2016-07-12 2018-01-18 Galecto Biotech Ab Alpha-d-galactoside inhibitors of galectins
MX392945B (es) 2017-05-12 2025-03-19 Galectin Sciences Llc Compuestos para la prevencion y el tratamiento de enfermedades y el uso de los mismos.
EP3732186A1 (en) 2017-12-29 2020-11-04 GlycoMimetics, Inc. Heterobifunctional inhibitors of e-selectin and galectin-3
WO2020002765A1 (en) 2018-06-29 2020-01-02 Glykos Biomedical Oy Conjugates
JP7547345B2 (ja) 2018-12-27 2024-09-09 グリコミメティクス, インコーポレイテッド ガレクチン-3阻害性c-グリコシド
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
EP4010348B1 (en) * 2019-08-09 2023-12-20 Idorsia Pharmaceuticals Ltd (2-acetamidyl)thio-beta-d-galactopyranoside derivatives
WO2021123506A1 (en) 2019-12-18 2021-06-24 Glykos Biomedical Oy Stabile conjugate
CZ2023132A3 (cs) 2023-04-04 2024-10-16 Ústav Chemických Procesů Av Čr, V. V. I. Komplexy ruthenia pro inhibici galektinů, způsob jejich výroby a jejich použití

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0100172D0 (sv) * 2001-01-22 2001-01-22 Ulf Nilsson New inhibitors against galectins
SE0401301D0 (sv) 2004-05-21 2004-05-21 Forskarpatent I Syd Ab Novel 3-triazolyl-galactoside inhibitors of galectins
SE0401300D0 (sv) 2004-05-21 2004-05-21 Forskarpatent I Syd Ab Novel Galactoside Inhibitors of Galectins
WO2009139719A1 (en) 2008-05-16 2009-11-19 Forskarpatent I Syd Ab Novel synthesis of galactoside inhibitors
EP2424873B1 (en) 2009-04-28 2017-11-15 Galecto Biotech AB Novel galactoside inhibitors of galectins
CA2884802A1 (en) 2012-10-31 2014-05-08 Galecto Biotech Ab Galactoside inhibitor of galectin-3 and its use for treating pulmonary fibrosis

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