JP2015504847A - 前立腺癌骨転移および薬剤耐性肺癌を治療するためのマイクロrnamir−409−5p、mir−379、およびmir−154*の標的化 - Google Patents
前立腺癌骨転移および薬剤耐性肺癌を治療するためのマイクロrnamir−409−5p、mir−379、およびmir−154*の標的化 Download PDFInfo
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161565226P | 2011-11-30 | 2011-11-30 | |
| US61/565,226 | 2011-11-30 | ||
| PCT/US2012/067403 WO2013082499A1 (en) | 2011-11-30 | 2012-11-30 | Targeting micrornas mir-409-5p, mir-379 and mir-154* to treat prostate cancer bone metastasis and drug resistant lung cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015504847A true JP2015504847A (ja) | 2015-02-16 |
| JP2015504847A5 JP2015504847A5 (enExample) | 2016-01-14 |
Family
ID=48536124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014544946A Pending JP2015504847A (ja) | 2011-11-30 | 2012-11-30 | 前立腺癌骨転移および薬剤耐性肺癌を治療するためのマイクロrnamir−409−5p、mir−379、およびmir−154*の標的化 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140323551A1 (enExample) |
| EP (2) | EP3106168A3 (enExample) |
| JP (1) | JP2015504847A (enExample) |
| CN (1) | CN104080461A (enExample) |
| AU (1) | AU2012345666A1 (enExample) |
| WO (1) | WO2013082499A1 (enExample) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016508148A (ja) * | 2013-01-07 | 2016-03-17 | エーアールオージー ファーマスーティカルズ,インクArog Pharmaceuticals, Inc. | 変異flt3増殖性障害の治療剤クレノラニブ(crenolanib) |
| US9745578B2 (en) | 2011-11-30 | 2017-08-29 | Cedars-Sinai Medical Center | Targeting microRNA miR-409-3P to treat prostate cancer |
| KR20190022310A (ko) | 2017-08-25 | 2019-03-06 | 삼성전자주식회사 | 전고체형 이차전지 |
| US10854877B2 (en) | 2017-08-25 | 2020-12-01 | Samsung Electronics Co., Ltd. | All-solid-state secondary battery |
| US11236337B2 (en) | 2016-11-01 | 2022-02-01 | The Research Foundation For The State University Of New York | 5-halouracil-modified microRNAs and their use in the treatment of cancer |
| US11584932B2 (en) | 2016-11-01 | 2023-02-21 | The Research Foundation For The State University Of New York | 5-halouracil-modified microRNAs and their use in the treatment of cancer |
| US12319913B2 (en) | 2018-10-31 | 2025-06-03 | The Research Foundation For The State University Of New York | 5-halouracil-modified microRNAs and their use in the treatment of cancer |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10801071B2 (en) * | 2014-04-22 | 2020-10-13 | The Johns Hopkins University | TGF(β)-MIR200-MIG6 pathway and its use in the treatment of cancer as an indicator of resistance to EGFR inhibitors |
| US10493165B2 (en) | 2015-01-30 | 2019-12-03 | The Johns Hopkins University | Extracellular vesicles for agent delivery |
| US10870852B2 (en) | 2015-10-06 | 2020-12-22 | University Of Virginia Patent Foundation | Compositions and methods for treating diabetic retinopathy |
| US20190269801A1 (en) | 2016-10-21 | 2019-09-05 | Cedars-Sinai Medical Center | Simvastatin and chemotherapeutic conjugates with a heptamethine carbocyanine dye resensitize human tumors to hormonal antagonists and chemotherapy |
| MX393780B (es) | 2017-01-17 | 2025-03-24 | Heparegenix Gmbh | Inhibidores de proteina cinasa para promover la regeneracion hepatica o reducir o prevenir la muerte de hepatocitos |
| CN107488734B (zh) * | 2017-10-10 | 2019-11-05 | 广州医科大学附属第二医院 | miR-19a-3p在制备前列腺癌骨转移诊断试剂和治疗药物中的应用 |
| CN107630092B (zh) * | 2017-10-23 | 2020-03-31 | 广州医科大学附属第二医院 | miR-505-3p应用于前列腺癌骨转移的诊断、预后和治疗 |
| CN108148911B (zh) * | 2018-03-02 | 2019-11-05 | 广州医科大学附属第二医院 | miR-582在制备前列腺癌骨转移的诊断、预后试剂盒及药物中的应用 |
| KR102132222B1 (ko) * | 2018-11-27 | 2020-07-09 | 강원대학교산학협력단 | 항암제 내성 진단 마커로서의 miR-143-3p 및 miR-373-5p, 및 이의 이용 |
| CN110305863B (zh) * | 2019-06-10 | 2020-12-08 | 浙江大学 | 用于上调人DLK1-DIO3印记域非编码RNA表达的sgRNA、重组质粒和细胞株 |
| CN110819718B (zh) * | 2019-12-16 | 2023-05-26 | 广州医科大学附属第二医院 | miR-154-5p在前列腺癌骨转移的新应用 |
| JP2023521356A (ja) * | 2020-04-07 | 2023-05-24 | アドヴァンスド セル ダイアグノスティクス,インコーポレイテッド | in situハイブリダイゼーションによって標的核酸を検出する方法及びそのキット |
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| JP2008519606A (ja) * | 2004-11-12 | 2008-06-12 | アンビオン インコーポレーティッド | miRNAおよびmiRNA阻害分子に関する方法および組成物 |
| WO2010056737A2 (en) * | 2008-11-11 | 2010-05-20 | Mirna Therapeutics, Inc. | Methods and compositions involving mirnas in cancer stem cells |
| CN102080085A (zh) * | 2009-12-01 | 2011-06-01 | 中国科学院上海药物研究所 | 人miR-193b反义核酸及其应用 |
| WO2011076142A1 (en) * | 2009-12-24 | 2011-06-30 | Fudan University | Compositions and methods for microrna expession profiling in plasma of colorectal cancer |
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| EP1784501B1 (en) * | 2004-05-14 | 2015-11-18 | Rosetta Genomics Ltd | VIRAL AND VIRUS ASSOCIATED MicroRNAS AND USES THEREOF |
| US20060265771A1 (en) * | 2005-05-17 | 2006-11-23 | Lewis David L | Monitoring microrna expression and function |
| US20070065844A1 (en) * | 2005-06-08 | 2007-03-22 | Massachusetts Institute Of Technology | Solution-based methods for RNA expression profiling |
| JP5489459B2 (ja) * | 2005-08-01 | 2014-05-14 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション | 乳癌の診断、予後及び治療のためのマイクロrnaに基づいた方法及び組成物 |
| CN101627121A (zh) * | 2006-12-08 | 2010-01-13 | 奥斯瑞根公司 | 作为治疗干预的靶标的miRNA调控基因和路径 |
| US20080311040A1 (en) * | 2007-03-06 | 2008-12-18 | Flagship Ventures | METHODS AND COMPOSITIONS FOR IMPROVED THERAPEUTIC EFFECTS WITH siRNA |
| PL2623598T3 (pl) * | 2007-10-04 | 2018-12-31 | Roche Innovation Center Copenhagen A/S | Micromir |
| ES2600165T3 (es) * | 2008-02-28 | 2017-02-07 | The Ohio State University Research Foundation | Antagonistas de miR-32 para aumentar la respuesta del cáncer de próstata a la apoptosis |
| AU2010249421A1 (en) * | 2009-05-22 | 2011-12-08 | Asuragen, Inc. | miRNA biomarkers of prostate disease |
-
2012
- 2012-11-30 EP EP16170595.9A patent/EP3106168A3/en not_active Withdrawn
- 2012-11-30 US US14/360,489 patent/US20140323551A1/en not_active Abandoned
- 2012-11-30 JP JP2014544946A patent/JP2015504847A/ja active Pending
- 2012-11-30 EP EP12854115.8A patent/EP2785355A4/en not_active Withdrawn
- 2012-11-30 CN CN201280067969.XA patent/CN104080461A/zh active Pending
- 2012-11-30 WO PCT/US2012/067403 patent/WO2013082499A1/en not_active Ceased
- 2012-11-30 AU AU2012345666A patent/AU2012345666A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008519606A (ja) * | 2004-11-12 | 2008-06-12 | アンビオン インコーポレーティッド | miRNAおよびmiRNA阻害分子に関する方法および組成物 |
| WO2010056737A2 (en) * | 2008-11-11 | 2010-05-20 | Mirna Therapeutics, Inc. | Methods and compositions involving mirnas in cancer stem cells |
| CN102080085A (zh) * | 2009-12-01 | 2011-06-01 | 中国科学院上海药物研究所 | 人miR-193b反义核酸及其应用 |
| WO2011076142A1 (en) * | 2009-12-24 | 2011-06-30 | Fudan University | Compositions and methods for microrna expession profiling in plasma of colorectal cancer |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9745578B2 (en) | 2011-11-30 | 2017-08-29 | Cedars-Sinai Medical Center | Targeting microRNA miR-409-3P to treat prostate cancer |
| JP2016508148A (ja) * | 2013-01-07 | 2016-03-17 | エーアールオージー ファーマスーティカルズ,インクArog Pharmaceuticals, Inc. | 変異flt3増殖性障害の治療剤クレノラニブ(crenolanib) |
| US11236337B2 (en) | 2016-11-01 | 2022-02-01 | The Research Foundation For The State University Of New York | 5-halouracil-modified microRNAs and their use in the treatment of cancer |
| US11584932B2 (en) | 2016-11-01 | 2023-02-21 | The Research Foundation For The State University Of New York | 5-halouracil-modified microRNAs and their use in the treatment of cancer |
| US12371693B2 (en) | 2016-11-01 | 2025-07-29 | The Research Foundation For The State University Of New York | 5-halouracil-modified micrornas and their use in the treatment of cancer |
| KR20190022310A (ko) | 2017-08-25 | 2019-03-06 | 삼성전자주식회사 | 전고체형 이차전지 |
| US10854877B2 (en) | 2017-08-25 | 2020-12-01 | Samsung Electronics Co., Ltd. | All-solid-state secondary battery |
| US12319913B2 (en) | 2018-10-31 | 2025-06-03 | The Research Foundation For The State University Of New York | 5-halouracil-modified microRNAs and their use in the treatment of cancer |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104080461A (zh) | 2014-10-01 |
| AU2012345666A1 (en) | 2014-06-19 |
| WO2013082499A1 (en) | 2013-06-06 |
| EP3106168A2 (en) | 2016-12-21 |
| EP2785355A4 (en) | 2015-12-02 |
| EP3106168A3 (en) | 2017-02-22 |
| EP2785355A1 (en) | 2014-10-08 |
| US20140323551A1 (en) | 2014-10-30 |
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