JP2015504847A5 - - Google Patents

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Publication number
JP2015504847A5
JP2015504847A5 JP2014544946A JP2014544946A JP2015504847A5 JP 2015504847 A5 JP2015504847 A5 JP 2015504847A5 JP 2014544946 A JP2014544946 A JP 2014544946A JP 2014544946 A JP2014544946 A JP 2014544946A JP 2015504847 A5 JP2015504847 A5 JP 2015504847A5
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JP
Japan
Prior art keywords
mir
cancer
seq
metastatic
mirna
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Pending
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JP2014544946A
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English (en)
Japanese (ja)
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JP2015504847A (ja
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Priority claimed from PCT/US2012/067403 external-priority patent/WO2013082499A1/en
Publication of JP2015504847A publication Critical patent/JP2015504847A/ja
Publication of JP2015504847A5 publication Critical patent/JP2015504847A5/ja
Pending legal-status Critical Current

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JP2014544946A 2011-11-30 2012-11-30 前立腺癌骨転移および薬剤耐性肺癌を治療するためのマイクロrnamir−409−5p、mir−379、およびmir−154*の標的化 Pending JP2015504847A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161565226P 2011-11-30 2011-11-30
US61/565,226 2011-11-30
PCT/US2012/067403 WO2013082499A1 (en) 2011-11-30 2012-11-30 Targeting micrornas mir-409-5p, mir-379 and mir-154* to treat prostate cancer bone metastasis and drug resistant lung cancer

Publications (2)

Publication Number Publication Date
JP2015504847A JP2015504847A (ja) 2015-02-16
JP2015504847A5 true JP2015504847A5 (enExample) 2016-01-14

Family

ID=48536124

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014544946A Pending JP2015504847A (ja) 2011-11-30 2012-11-30 前立腺癌骨転移および薬剤耐性肺癌を治療するためのマイクロrnamir−409−5p、mir−379、およびmir−154*の標的化

Country Status (6)

Country Link
US (1) US20140323551A1 (enExample)
EP (2) EP3106168A3 (enExample)
JP (1) JP2015504847A (enExample)
CN (1) CN104080461A (enExample)
AU (1) AU2012345666A1 (enExample)
WO (1) WO2013082499A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9745578B2 (en) 2011-11-30 2017-08-29 Cedars-Sinai Medical Center Targeting microRNA miR-409-3P to treat prostate cancer
BR112015016282A2 (en) * 2013-01-07 2017-07-11 Arog Pharmaceuticals, Inc. crenolanib for treatment of mutated flt3 proliferative disorders
EP3134547B1 (en) * 2014-04-22 2019-07-10 The Johns Hopkins University The tgf(beta)-mir200-mig6 pathway and its use in the treatment of cancer as an indicator of resistance to egfr inhibitors
HK1247964A1 (zh) 2015-01-30 2018-10-05 The Johns Hopkins University 用於活性剂递送的细胞外囊泡
US10870852B2 (en) 2015-10-06 2020-12-22 University Of Virginia Patent Foundation Compositions and methods for treating diabetic retinopathy
EP3529315B1 (en) * 2016-10-21 2024-12-04 Da Zen Theranostics, Inc Near infrared (nir) dye cancer drug conjugated to a statin
US11584932B2 (en) 2016-11-01 2023-02-21 The Research Foundation For The State University Of New York 5-halouracil-modified microRNAs and their use in the treatment of cancer
US11236337B2 (en) 2016-11-01 2022-02-01 The Research Foundation For The State University Of New York 5-halouracil-modified microRNAs and their use in the treatment of cancer
ES2928773T3 (es) 2017-01-17 2022-11-22 Heparegenix Gmbh Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos
US10854877B2 (en) 2017-08-25 2020-12-01 Samsung Electronics Co., Ltd. All-solid-state secondary battery
JP7164939B2 (ja) 2017-08-25 2022-11-02 株式会社サムスン日本研究所 全固体型二次電池
CN107488734B (zh) * 2017-10-10 2019-11-05 广州医科大学附属第二医院 miR-19a-3p在制备前列腺癌骨转移诊断试剂和治疗药物中的应用
CN107630092B (zh) * 2017-10-23 2020-03-31 广州医科大学附属第二医院 miR-505-3p应用于前列腺癌骨转移的诊断、预后和治疗
CN108148911B (zh) * 2018-03-02 2019-11-05 广州医科大学附属第二医院 miR-582在制备前列腺癌骨转移的诊断、预后试剂盒及药物中的应用
KR102132222B1 (ko) * 2018-11-27 2020-07-09 강원대학교산학협력단 항암제 내성 진단 마커로서의 miR-143-3p 및 miR-373-5p, 및 이의 이용
CN110305863B (zh) * 2019-06-10 2020-12-08 浙江大学 用于上调人DLK1-DIO3印记域非编码RNA表达的sgRNA、重组质粒和细胞株
CN110819718B (zh) * 2019-12-16 2023-05-26 广州医科大学附属第二医院 miR-154-5p在前列腺癌骨转移的新应用
JP2023521356A (ja) 2020-04-07 2023-05-24 アドヴァンスド セル ダイアグノスティクス,インコーポレイテッド in situハイブリダイゼーションによって標的核酸を検出する方法及びそのキット
WO2021262919A2 (en) 2020-06-26 2021-12-30 The Research Foundation For The State University Of New York 5-halouracil-modified micrornas and their use in the treatment of cancer

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5697297B2 (ja) * 2004-05-14 2015-04-08 ロゼッタ ジノミクス リミテッド マイクロnasおよびその使用
EP2302055B1 (en) * 2004-11-12 2014-08-27 Asuragen, Inc. Methods and compositions involving miRNA and miRNA inhibitor molecules
US20060265771A1 (en) * 2005-05-17 2006-11-23 Lewis David L Monitoring microrna expression and function
US20070065844A1 (en) * 2005-06-08 2007-03-22 Massachusetts Institute Of Technology Solution-based methods for RNA expression profiling
CN103820562B (zh) * 2005-08-01 2015-05-13 俄亥俄州立大学研究基金会 用于乳腺癌的诊断、预后和治疗的基于MicroRNA的方法和组合物
WO2008073915A2 (en) * 2006-12-08 2008-06-19 Asuragen, Inc. Micrornas differentially expressed in leukemia and uses thereof
US20080311040A1 (en) * 2007-03-06 2008-12-18 Flagship Ventures METHODS AND COMPOSITIONS FOR IMPROVED THERAPEUTIC EFFECTS WITH siRNA
EP2623599B1 (en) * 2007-10-04 2019-01-02 Roche Innovation Center Copenhagen A/S Micromirs
CN102027129B (zh) * 2008-02-28 2014-03-12 俄亥俄州立大学研究基金会 用于前列腺相关病症的诊断、预后和治疗的基于微rna的方法和组合物
WO2010056737A2 (en) * 2008-11-11 2010-05-20 Mirna Therapeutics, Inc. Methods and compositions involving mirnas in cancer stem cells
EP2634266B1 (en) * 2009-05-22 2015-10-14 Asuragen, INC. miRNA biomarkers of prostate disease
CN102080085B (zh) * 2009-12-01 2013-01-16 中国科学院上海药物研究所 人miR-193b反义核酸及其应用
WO2011076142A1 (en) * 2009-12-24 2011-06-30 Fudan University Compositions and methods for microrna expession profiling in plasma of colorectal cancer

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