JP2015504661A5 - - Google Patents
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- JP2015504661A5 JP2015504661A5 JP2014548844A JP2014548844A JP2015504661A5 JP 2015504661 A5 JP2015504661 A5 JP 2015504661A5 JP 2014548844 A JP2014548844 A JP 2014548844A JP 2014548844 A JP2014548844 A JP 2014548844A JP 2015504661 A5 JP2015504661 A5 JP 2015504661A5
- Authority
- JP
- Japan
- Prior art keywords
- chronotype
- same
- clan
- region
- profile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 18
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 108020004511 Recombinant DNA Proteins 0.000 claims 3
- 108700005091 Immunoglobulin Genes Proteins 0.000 claims 2
- 210000003719 b-lymphocyte Anatomy 0.000 claims 2
- 201000003444 follicular lymphoma Diseases 0.000 claims 2
- 238000012804 iterative process Methods 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 230000009466 transformation Effects 0.000 claims 2
- 208000003950 B-cell lymphoma Diseases 0.000 claims 1
- 208000031671 Large B-Cell Diffuse Lymphoma Diseases 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 206010012818 diffuse large B-cell lymphoma Diseases 0.000 claims 1
- 238000013507 mapping Methods 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 238000005215 recombination Methods 0.000 claims 1
- 230000006798 recombination Effects 0.000 claims 1
- 230000003252 repetitive effect Effects 0.000 claims 1
- 238000012163 sequencing technique Methods 0.000 claims 1
- 238000011144 upstream manufacturing Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161578175P | 2011-12-20 | 2011-12-20 | |
| US61/578,175 | 2011-12-20 | ||
| PCT/US2012/070674 WO2013096480A2 (en) | 2011-12-20 | 2012-12-19 | Monitoring transformation of follicular lymphoma to diffuse large b-cell lymphoma by immune repertoire analysis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015504661A JP2015504661A (ja) | 2015-02-16 |
| JP2015504661A5 true JP2015504661A5 (enExample) | 2017-01-19 |
Family
ID=48669695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014548844A Pending JP2015504661A (ja) | 2011-12-20 | 2012-12-19 | 免疫レパートリー解析による、濾胞性リンパ腫からびまん性大細胞型ｂ細胞リンパ腫への形質転換のモニタリング |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20140349883A1 (enExample) |
| EP (1) | EP2794925A4 (enExample) |
| JP (1) | JP2015504661A (enExample) |
| WO (1) | WO2013096480A2 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
| US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
| EP3699296A1 (en) | 2008-11-07 | 2020-08-26 | Adaptive Biotechnologies Corporation | Methods of monitoring conditions by sequence analysis |
| US9394567B2 (en) | 2008-11-07 | 2016-07-19 | Adaptive Biotechnologies Corporation | Detection and quantification of sample contamination in immune repertoire analysis |
| US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
| US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| HUE029424T2 (en) | 2009-01-15 | 2017-02-28 | Adaptive Biotechnologies Corp | Adaptive immunity profiling and a method for producing monoclonal antibodies |
| RU2014144463A (ru) | 2009-06-25 | 2015-06-20 | Фред Хатчинсон Кансэр Рисёч Сентер | Способ измерения адаптивного иммунитета |
| US9043160B1 (en) | 2009-11-09 | 2015-05-26 | Sequenta, Inc. | Method of determining clonotypes and clonotype profiles |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| AU2012325791B2 (en) | 2011-10-21 | 2018-04-05 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| EP2788509B1 (en) | 2011-12-09 | 2018-07-11 | Adaptive Biotechnologies Corporation | Diagnosis of lymphoid malignancies and minimal residual disease detection |
| US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
| ES2662128T3 (es) | 2012-03-05 | 2018-04-05 | Adaptive Biotechnologies Corporation | Determinación de cadenas de receptor inmunitario emparejadas a partir de la frecuencia de subunidades coincidentes |
| PT2831276T (pt) | 2012-05-08 | 2016-07-26 | Adaptive Biotechnologies Corp | Composições e método para medição e calibração do viés de amplificação em reações pcr multiplex |
| ES2660027T3 (es) | 2012-10-01 | 2018-03-20 | Adaptive Biotechnologies Corporation | Evaluación de la inmunocompetencia por la diversidad de los receptores de inmunidad adaptativa y caracterización de la clonalidad |
| US9708657B2 (en) * | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| WO2015134787A2 (en) | 2014-03-05 | 2015-09-11 | Adaptive Biotechnologies Corporation | Methods using randomer-containing synthetic molecules |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| EP3132059B1 (en) | 2014-04-17 | 2020-01-08 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| EP3715455A1 (en) | 2014-10-29 | 2020-09-30 | Adaptive Biotechnologies Corp. | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| US11066705B2 (en) | 2014-11-25 | 2021-07-20 | Adaptive Biotechnologies Corporation | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
| WO2016138122A1 (en) | 2015-02-24 | 2016-09-01 | Adaptive Biotechnologies Corp. | Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing |
| US11041202B2 (en) | 2015-04-01 | 2021-06-22 | Adaptive Biotechnologies Corporation | Method of identifying human compatible T cell receptors specific for an antigenic target |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8748103B2 (en) * | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| JP6158080B2 (ja) * | 2010-05-06 | 2017-07-05 | アダプティヴ バイオテクノロジーズ コーポレーション | クロノタイププロファイルを用いた健康状態および疾患状態のモニタリング |
-
2012
- 2012-12-19 US US14/366,840 patent/US20140349883A1/en not_active Abandoned
- 2012-12-19 WO PCT/US2012/070674 patent/WO2013096480A2/en not_active Ceased
- 2012-12-19 JP JP2014548844A patent/JP2015504661A/ja active Pending
- 2012-12-19 EP EP12859772.1A patent/EP2794925A4/en not_active Withdrawn
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