JP2015504661A - 免疫レパートリー解析による、濾胞性リンパ腫からびまん性大細胞型ｂ細胞リンパ腫への形質転換のモニタリング - Google Patents

免疫レパートリー解析による、濾胞性リンパ腫からびまん性大細胞型ｂ細胞リンパ腫への形質転換のモニタリング Download PDF

Info

Publication number
JP2015504661A
JP2015504661A JP2014548844A JP2014548844A JP2015504661A JP 2015504661 A JP2015504661 A JP 2015504661A JP 2014548844 A JP2014548844 A JP 2014548844A JP 2014548844 A JP2014548844 A JP 2014548844A JP 2015504661 A JP2015504661 A JP 2015504661A
Authority
JP
Japan
Prior art keywords
chronotype
region
clan
sequence
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014548844A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015504661A5 (enExample
Inventor
マレク ファハム
マレク ファハム
Original Assignee
シーケンタ インコーポレイテッド
シーケンタ インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by シーケンタ インコーポレイテッド, シーケンタ インコーポレイテッド filed Critical シーケンタ インコーポレイテッド
Publication of JP2015504661A publication Critical patent/JP2015504661A/ja
Publication of JP2015504661A5 publication Critical patent/JP2015504661A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2014548844A 2011-12-20 2012-12-19 免疫レパートリー解析による、濾胞性リンパ腫からびまん性大細胞型ｂ細胞リンパ腫への形質転換のモニタリング Pending JP2015504661A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161578175P 2011-12-20 2011-12-20
US61/578,175 2011-12-20
PCT/US2012/070674 WO2013096480A2 (en) 2011-12-20 2012-12-19 Monitoring transformation of follicular lymphoma to diffuse large b-cell lymphoma by immune repertoire analysis

Publications (2)

Publication Number Publication Date
JP2015504661A true JP2015504661A (ja) 2015-02-16
JP2015504661A5 JP2015504661A5 (enExample) 2017-01-19

Family

ID=48669695

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014548844A Pending JP2015504661A (ja) 2011-12-20 2012-12-19 免疫レパートリー解析による、濾胞性リンパ腫からびまん性大細胞型ｂ細胞リンパ腫への形質転換のモニタリング

Country Status (4)

Country Link
US (1) US20140349883A1 (enExample)
EP (1) EP2794925A4 (enExample)
JP (1) JP2015504661A (enExample)
WO (1) WO2013096480A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023511200A (ja) * 2020-01-22 2023-03-16 ライフ テクノロジーズ コーポレーション 自己免疫疾患および免疫不全疾患における免疫レパートリーバイオマーカー
JP7787078B2 (ja) 2020-01-22 2025-12-16 ライフ テクノロジーズ コーポレーション 自己免疫疾患および免疫不全疾患における免疫レパートリーバイオマーカー

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9506119B2 (en) 2008-11-07 2016-11-29 Adaptive Biotechnologies Corp. Method of sequence determination using sequence tags
US9365901B2 (en) 2008-11-07 2016-06-14 Adaptive Biotechnologies Corp. Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
EP3699296A1 (en) 2008-11-07 2020-08-26 Adaptive Biotechnologies Corporation Methods of monitoring conditions by sequence analysis
US9394567B2 (en) 2008-11-07 2016-07-19 Adaptive Biotechnologies Corporation Detection and quantification of sample contamination in immune repertoire analysis
US9528160B2 (en) 2008-11-07 2016-12-27 Adaptive Biotechnolgies Corp. Rare clonotypes and uses thereof
US8748103B2 (en) 2008-11-07 2014-06-10 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
US8628927B2 (en) 2008-11-07 2014-01-14 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
HUE029424T2 (en) 2009-01-15 2017-02-28 Adaptive Biotechnologies Corp Adaptive immunity profiling and a method for producing monoclonal antibodies
RU2014144463A (ru) 2009-06-25 2015-06-20 Фред Хатчинсон Кансэр Рисёч Сентер Способ измерения адаптивного иммунитета
US9043160B1 (en) 2009-11-09 2015-05-26 Sequenta, Inc. Method of determining clonotypes and clonotype profiles
US10385475B2 (en) 2011-09-12 2019-08-20 Adaptive Biotechnologies Corp. Random array sequencing of low-complexity libraries
AU2012325791B2 (en) 2011-10-21 2018-04-05 Adaptive Biotechnologies Corporation Quantification of adaptive immune cell genomes in a complex mixture of cells
EP2788509B1 (en) 2011-12-09 2018-07-11 Adaptive Biotechnologies Corporation Diagnosis of lymphoid malignancies and minimal residual disease detection
US9499865B2 (en) 2011-12-13 2016-11-22 Adaptive Biotechnologies Corp. Detection and measurement of tissue-infiltrating lymphocytes
ES2662128T3 (es) 2012-03-05 2018-04-05 Adaptive Biotechnologies Corporation Determinación de cadenas de receptor inmunitario emparejadas a partir de la frecuencia de subunidades coincidentes
PT2831276T (pt) 2012-05-08 2016-07-26 Adaptive Biotechnologies Corp Composições e método para medição e calibração do viés de amplificação em reações pcr multiplex
ES2660027T3 (es) 2012-10-01 2018-03-20 Adaptive Biotechnologies Corporation Evaluación de la inmunocompetencia por la diversidad de los receptores de inmunidad adaptativa y caracterización de la clonalidad
US9708657B2 (en) * 2013-07-01 2017-07-18 Adaptive Biotechnologies Corp. Method for generating clonotype profiles using sequence tags
WO2015134787A2 (en) 2014-03-05 2015-09-11 Adaptive Biotechnologies Corporation Methods using randomer-containing synthetic molecules
US10066265B2 (en) 2014-04-01 2018-09-04 Adaptive Biotechnologies Corp. Determining antigen-specific t-cells
EP3132059B1 (en) 2014-04-17 2020-01-08 Adaptive Biotechnologies Corporation Quantification of adaptive immune cell genomes in a complex mixture of cells
EP3715455A1 (en) 2014-10-29 2020-09-30 Adaptive Biotechnologies Corp. Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples
US10246701B2 (en) 2014-11-14 2019-04-02 Adaptive Biotechnologies Corp. Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
US11066705B2 (en) 2014-11-25 2021-07-20 Adaptive Biotechnologies Corporation Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing
WO2016138122A1 (en) 2015-02-24 2016-09-01 Adaptive Biotechnologies Corp. Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing
US11041202B2 (en) 2015-04-01 2021-06-22 Adaptive Biotechnologies Corporation Method of identifying human compatible T cell receptors specific for an antigenic target
US10428325B1 (en) 2016-09-21 2019-10-01 Adaptive Biotechnologies Corporation Identification of antigen-specific B cell receptors
US11254980B1 (en) 2017-11-29 2022-02-22 Adaptive Biotechnologies Corporation Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011139371A1 (en) * 2010-05-06 2011-11-10 Sequenta, Inc. Monitoring health and disease status using clonotype profiles

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8748103B2 (en) * 2008-11-07 2014-06-10 Sequenta, Inc. Monitoring health and disease status using clonotype profiles

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011139371A1 (en) * 2010-05-06 2011-11-10 Sequenta, Inc. Monitoring health and disease status using clonotype profiles

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BLOOD, 2009年, vol. 113, no. 15, JPN6017000355, pages 3553 - 3557, ISSN: 0003479099 *
BLOOD, vol. 98, no. 1, JPN6017000352, pages 238 - 240, ISSN: 0003479097 *
BR. J. HAEMATOL., 2007年, vol. 136, no. 2, JPN6017000353, pages 286 - 293, ISSN: 0003479098 *
EUR. J. IMMUNOL., 1999年, vol. 29, JPN6017000350, pages 1253 - 1264, ISSN: 0003479096 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023511200A (ja) * 2020-01-22 2023-03-16 ライフ テクノロジーズ コーポレーション 自己免疫疾患および免疫不全疾患における免疫レパートリーバイオマーカー
JP7787078B2 (ja) 2020-01-22 2025-12-16 ライフ テクノロジーズ コーポレーション 自己免疫疾患および免疫不全疾患における免疫レパートリーバイオマーカー

Also Published As

Publication number Publication date
EP2794925A2 (en) 2014-10-29
EP2794925A4 (en) 2015-09-30
WO2013096480A3 (en) 2014-09-18
WO2013096480A2 (en) 2013-06-27
US20140349883A1 (en) 2014-11-27

Similar Documents

Publication Publication Date Title
JP2015504661A (ja) 免疫レパートリー解析による、濾胞性リンパ腫からびまん性大細胞型ｂ細胞リンパ腫への形質転換のモニタリング
JP6085249B2 (ja) 複雑なアンプリコンの配列解析
JP6513035B2 (ja) 希少クロノタイプおよびその用途
JP6343563B2 (ja) 組織浸潤リンパ球の検出および測定方法
JP2015501644A (ja) 免疫活性化を測定する方法
US9043160B1 (en) Method of determining clonotypes and clonotype profiles
US20150031553A1 (en) Method of measuring immune activation
US9365901B2 (en) Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
US20150299800A1 (en) Monitoring mantle cell lymphoma clonotypes in peripheral blood after immunotransplant
US8691510B2 (en) Sequence analysis of complex amplicons
US20150247201A1 (en) Predicting relapse of chronic lymphocytic leukemia patients treated by allogeneic stem cell transplantation
US20140356339A1 (en) Sequence-based measures of immune response
US20140256592A1 (en) Determining responsiveness of autoimmune patients to dmard treatment
JP2015535178A (ja) 末梢血における形質細胞増殖障害のクロノタイプのモニタリング
JP2015534806A (ja) 末梢血試料によるびまん性大細胞型ｂ細胞性リンパ腫のモニタリング関連出願の相互参照本出願は、２０１２年１０月１９日出願の米国特許仮出願第６１／７１６，２７０号の利益を主張するものであり、当該出願は参照により本明細書にその全体が組み込まれる。
JP2015512655A (ja) 免疫レパートリ分析におけるサンプル混入の検出および定量化
CN105658812A (zh) 用序列标签进行大规模生物分子分析

Legal Events

Date Code Title Description
RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20150612

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20151118

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20151207

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20151207

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20151127

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160218

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A712

Effective date: 20160218

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20161214

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20170124

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20170905