JP2015504094A5 - - Google Patents
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- Publication number
- JP2015504094A5 JP2015504094A5 JP2014553457A JP2014553457A JP2015504094A5 JP 2015504094 A5 JP2015504094 A5 JP 2015504094A5 JP 2014553457 A JP2014553457 A JP 2014553457A JP 2014553457 A JP2014553457 A JP 2014553457A JP 2015504094 A5 JP2015504094 A5 JP 2015504094A5
- Authority
- JP
- Japan
- Prior art keywords
- sialic acid
- composition
- release formulation
- extended release
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 claims description 44
- 239000000203 mixture Substances 0.000 claims description 43
- 238000009472 formulation Methods 0.000 claims description 20
- 150000002148 esters Chemical class 0.000 claims description 17
- 150000003839 salts Chemical class 0.000 claims description 17
- 239000011780 sodium chloride Substances 0.000 claims description 17
- 239000012453 solvate Substances 0.000 claims description 17
- 229920000642 polymer Polymers 0.000 claims description 15
- 230000036470 plasma concentration Effects 0.000 claims description 10
- 206010028640 Myopathy Diseases 0.000 claims description 6
- 208000009640 Nonaka type Distal myopathy Diseases 0.000 claims description 6
- 201000008319 inclusion body myositis Diseases 0.000 claims description 6
- 201000010770 muscular disease Diseases 0.000 claims description 6
- 201000009623 myopathy Diseases 0.000 claims description 6
- 239000011159 matrix material Substances 0.000 claims description 5
- 239000007787 solid Substances 0.000 claims description 5
- 230000035839 C max Effects 0.000 claims description 4
- 229940113118 Carrageenan Drugs 0.000 claims description 4
- 229940005550 Sodium alginate Drugs 0.000 claims description 4
- 230000037098 T max Effects 0.000 claims description 4
- 235000010418 carrageenan Nutrition 0.000 claims description 4
- 239000000679 carrageenan Substances 0.000 claims description 4
- 229920001525 carrageenan Polymers 0.000 claims description 4
- 239000007891 compressed tablet Substances 0.000 claims description 4
- MSXHSNHNTORCAW-UHFFFAOYSA-M sodium 3,4,5,6-tetrahydroxyoxane-2-carboxylate Chemical compound [Na+].OC1OC(C([O-])=O)C(O)C(O)C1O MSXHSNHNTORCAW-UHFFFAOYSA-M 0.000 claims description 4
- 235000010413 sodium alginate Nutrition 0.000 claims description 4
- 239000000661 sodium alginate Substances 0.000 claims description 4
- 125000000129 anionic group Chemical group 0.000 claims description 3
- 125000002091 cationic group Chemical group 0.000 claims description 3
- 230000001419 dependent Effects 0.000 claims description 3
- 239000000416 hydrocolloid Substances 0.000 claims description 3
- 230000035888 Maximum plasma concentration Effects 0.000 claims description 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 2
- 239000002202 Polyethylene glycol Substances 0.000 claims description 2
- 238000010521 absorption reaction Methods 0.000 claims description 2
- 235000020937 fasting conditions Nutrition 0.000 claims description 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 2
- 229960003943 hypromellose Drugs 0.000 claims description 2
- 229920001223 polyethylene glycol Polymers 0.000 claims description 2
- 208000008425 Protein Deficiency Diseases 0.000 claims 3
- 210000003934 Vacuoles Anatomy 0.000 claims 1
- 230000002950 deficient Effects 0.000 claims 1
- 238000007688 edging Methods 0.000 claims 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 210000003802 Sputum Anatomy 0.000 description 1
- 235000020828 fasting Nutrition 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261588069P | 2012-01-18 | 2012-01-18 | |
| US61/588,069 | 2012-01-18 | ||
| US201261709549P | 2012-10-04 | 2012-10-04 | |
| US61/709,549 | 2012-10-04 | ||
| PCT/US2013/022167 WO2013109906A2 (en) | 2012-01-18 | 2013-01-18 | Methods and formulations for treating sialic acid deficiencies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017141883A Division JP2017186381A (ja) | 2012-01-18 | 2017-07-21 | シアル酸欠乏を処置するための方法および製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015504094A JP2015504094A (ja) | 2015-02-05 |
| JP2015504094A5 true JP2015504094A5 (ru) | 2015-11-12 |
Family
ID=48799814
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014553457A Pending JP2015504094A (ja) | 2012-01-18 | 2013-01-18 | シアル酸欠乏を処置するための方法および製剤 |
| JP2017141883A Pending JP2017186381A (ja) | 2012-01-18 | 2017-07-21 | シアル酸欠乏を処置するための方法および製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017141883A Pending JP2017186381A (ja) | 2012-01-18 | 2017-07-21 | シアル酸欠乏を処置するための方法および製剤 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP2804600A4 (ru) |
| JP (2) | JP2015504094A (ru) |
| KR (1) | KR20150000872A (ru) |
| CN (1) | CN104271125A (ru) |
| AU (1) | AU2013209610B2 (ru) |
| BR (1) | BR112014017587A8 (ru) |
| CA (1) | CA2862836A1 (ru) |
| IL (1) | IL233225A0 (ru) |
| WO (1) | WO2013109906A2 (ru) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9241896B2 (en) | 2008-12-19 | 2016-01-26 | Ultragenyx Pharmaceutical Inc. | Methods and formulations for treating sialic acid deficiencies |
| KR20140003380A (ko) | 2010-07-13 | 2014-01-09 | 울트라제닉스 파마수티컬 인코포레이티드 | 시알산 결함 치료용 방법들 및 제형들 |
| MX347541B (es) | 2011-10-24 | 2017-04-28 | Ultragenyx Pharmaceutical Inc | Analogos de acido sialico. |
| WO2017048817A1 (en) | 2015-09-14 | 2017-03-23 | Ultragenyx Pharmaceutical Inc. | Crystal forms of sialic acid or salt or solvate thereof |
| EP3486326A1 (en) | 2017-11-21 | 2019-05-22 | Jennewein Biotechnologie GmbH | Method for the purification of n-acetylneuraminic acid from a fermentation broth |
| CN117969774B (zh) * | 2024-04-02 | 2024-06-11 | 小仙炖霸州食品有限公司 | 一种自动化燕窝检测与分级系统 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2680842C (en) * | 2007-05-31 | 2015-11-24 | Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services National Institutes Of Health | N-acetyl mannosamine or derivatives thereof for use in treating a kidney disorder in a mammal |
| US20100159001A1 (en) * | 2008-12-19 | 2010-06-24 | Cardinal John R | Extended-Release Pharmaceutical Formulations |
| CN102427817B (zh) * | 2009-05-15 | 2015-02-11 | 财团法人日本健康科学振兴财团 | 起因于gne蛋白质功能降低的疾病的治疗用药物、食品组合物、食品添加剂 |
| KR20140003380A (ko) * | 2010-07-13 | 2014-01-09 | 울트라제닉스 파마수티컬 인코포레이티드 | 시알산 결함 치료용 방법들 및 제형들 |
| MX347541B (es) * | 2011-10-24 | 2017-04-28 | Ultragenyx Pharmaceutical Inc | Analogos de acido sialico. |
-
2013
- 2013-01-18 BR BR112014017587A patent/BR112014017587A8/pt not_active Application Discontinuation
- 2013-01-18 KR KR1020147022912A patent/KR20150000872A/ko not_active Application Discontinuation
- 2013-01-18 WO PCT/US2013/022167 patent/WO2013109906A2/en active Application Filing
- 2013-01-18 EP EP13739040.7A patent/EP2804600A4/en not_active Withdrawn
- 2013-01-18 CA CA2862836A patent/CA2862836A1/en not_active Abandoned
- 2013-01-18 AU AU2013209610A patent/AU2013209610B2/en not_active Expired - Fee Related
- 2013-01-18 CN CN201380015020.XA patent/CN104271125A/zh active Pending
- 2013-01-18 JP JP2014553457A patent/JP2015504094A/ja active Pending
-
2014
- 2014-06-18 IL IL233225A patent/IL233225A0/en unknown
-
2017
- 2017-07-21 JP JP2017141883A patent/JP2017186381A/ja active Pending
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