JP2015503560A5 - - Google Patents
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- Publication number
- JP2015503560A5 JP2015503560A5 JP2014550335A JP2014550335A JP2015503560A5 JP 2015503560 A5 JP2015503560 A5 JP 2015503560A5 JP 2014550335 A JP2014550335 A JP 2014550335A JP 2014550335 A JP2014550335 A JP 2014550335A JP 2015503560 A5 JP2015503560 A5 JP 2015503560A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- solid dispersion
- hcv
- solid
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161581146P | 2011-12-29 | 2011-12-29 | |
| US61/581,146 | 2011-12-29 | ||
| US201261645696P | 2012-05-11 | 2012-05-11 | |
| US61/645,696 | 2012-05-11 | ||
| PCT/US2012/070349 WO2013101550A1 (en) | 2011-12-29 | 2012-12-18 | Solid compositions comprising an hcv inhibitor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015140513A Division JP2015227352A (ja) | 2011-12-29 | 2015-07-14 | Hcv阻害剤を含む固体組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015503560A JP2015503560A (ja) | 2015-02-02 |
| JP2015503560A5 true JP2015503560A5 (cg-RX-API-DMAC10.html) | 2015-03-12 |
| JP5781706B2 JP5781706B2 (ja) | 2015-09-24 |
Family
ID=47470243
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014550335A Expired - Fee Related JP5781706B2 (ja) | 2011-12-29 | 2012-12-18 | Hcv阻害剤を含む固体組成物 |
| JP2015140513A Pending JP2015227352A (ja) | 2011-12-29 | 2015-07-14 | Hcv阻害剤を含む固体組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015140513A Pending JP2015227352A (ja) | 2011-12-29 | 2015-07-14 | Hcv阻害剤を含む固体組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20130172239A1 (cg-RX-API-DMAC10.html) |
| EP (2) | EP2907505A3 (cg-RX-API-DMAC10.html) |
| JP (2) | JP5781706B2 (cg-RX-API-DMAC10.html) |
| CN (1) | CN104010631B (cg-RX-API-DMAC10.html) |
| CA (1) | CA2857339C (cg-RX-API-DMAC10.html) |
| DE (1) | DE212012000197U1 (cg-RX-API-DMAC10.html) |
| HK (1) | HK1201186A1 (cg-RX-API-DMAC10.html) |
| MX (1) | MX2014008008A (cg-RX-API-DMAC10.html) |
| WO (1) | WO2013101550A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20180237T4 (hr) | 2011-09-16 | 2020-12-11 | Gilead Pharmasset Llc | Metode za liječenje hcv-a |
| US20130164260A1 (en) | 2011-11-16 | 2013-06-27 | Gilead Sciences, Inc. | Antiviral compounds |
| US9326973B2 (en) | 2012-01-13 | 2016-05-03 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| ES2673870T3 (es) * | 2012-05-07 | 2018-06-26 | Bristol-Myers Squibb Holdings Ireland | Formulación de dosificación oral sólida de [(1S)-1-{[(2S,4R)-4-(7-cloro-4-metoxiisoquinolin-1-iloxi)-2-({(1R,2S)-1-[(ciclopropilsulfonil) carbamoil]-2-etenilciclopropil} carbamoil) pirrolidin-1-il] carbonil}-2,2-dimetil-propil] carbamato de 1,1-dimetiletilo |
| US8969588B2 (en) * | 2012-06-05 | 2015-03-03 | Gilead Pharmasset Llc | Solid forms of an antiviral compound |
| TW201446286A (zh) * | 2013-01-31 | 2014-12-16 | Gilead Pharmasset Llc | 抗病毒化合物之固態分散調製劑 |
| EP2950786B1 (en) | 2013-01-31 | 2019-11-27 | Gilead Pharmasset LLC | Combination formulation of two antiviral compounds |
| AU2014233705C1 (en) * | 2013-03-15 | 2019-10-10 | Boehringer Ingelheim International Gmbh | Solid oral dosage formulation of HCV inhibitor in the amorphous state |
| SG11201507468TA (en) * | 2013-03-15 | 2015-10-29 | Achillion Pharmaceuticals Inc | Sovaprevir tablets |
| AU2014250762A1 (en) | 2013-04-12 | 2015-10-29 | Achillion Pharmaceuticals, Inc. | Highly active nucleoside derivative for the treatment of HCV |
| US20150023913A1 (en) | 2013-07-02 | 2015-01-22 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US9717712B2 (en) | 2013-07-02 | 2017-08-01 | Bristol-Myers Squibb Company | Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus |
| JP2016527232A (ja) | 2013-07-17 | 2016-09-08 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | Hcvの治療に使用するためのビフェニル誘導体を含む組み合わせ |
| EA201690473A1 (ru) * | 2013-08-27 | 2017-03-31 | ГАЙЛИД ФАРМАССЕТ ЭлЭлСи | Комбинированный состав двух противовирусных соединений |
| WO2015119924A2 (en) * | 2014-02-05 | 2015-08-13 | Merck Sharp & Dohme Corp. | Fixed-dose combinations of antiviral compounds |
| EP3102188A4 (en) * | 2014-02-05 | 2017-07-12 | Merck Sharp & Dohme Corp. | Novel disintegration systems for pharmaceutical dosage forms |
| EP3102210A4 (en) * | 2014-02-05 | 2017-10-11 | Merck Sharp & Dohme Corp. | Pharmaceutical composition of selective hcv ns3/4a inhibitors |
| EP3125868A2 (en) * | 2014-04-03 | 2017-02-08 | Sandoz AG | Solid composition comprising amorphous sofosbuvir |
| TWI721947B (zh) | 2014-06-11 | 2021-03-21 | 美商基利法瑪席特有限責任公司 | 抗病毒化合物的固態形式 |
| WO2016038542A2 (en) * | 2014-09-10 | 2016-03-17 | Mylan Laboratories Limited | Polymorphic forms of sofosbuvir |
| WO2016075588A1 (en) * | 2014-11-11 | 2016-05-19 | Sun Pharmaceutical Industries Limited | Stable amorphous daclatasvir dihydrochloride |
| CA2975813A1 (en) * | 2015-02-13 | 2016-08-18 | Sandoz Ag | Pharmaceutical compositions comprising ledipasvir and sofosbuvir |
| WO2016145269A1 (en) | 2015-03-12 | 2016-09-15 | Teva Pharmaceuticals International Gmbh | Solid state forms ledipasvir and processes for preparation of ledipasvir |
| WO2017021904A1 (en) * | 2015-08-03 | 2017-02-09 | Laurus Labs Private Limited | Daclatasvir free base and process for the preparation thereof |
| WO2017023714A1 (en) * | 2015-08-04 | 2017-02-09 | Merck Sharp & Dohme Corp. | Fixed-dose combinations of antiviral compounds |
| US20180228827A1 (en) * | 2015-08-04 | 2018-08-16 | Merck Sharp & Dohme Corp. | Fixed-dose combinations of antiviral compounds |
| WO2017023716A1 (en) * | 2015-08-04 | 2017-02-09 | Merck Sharp & Dohme Corp. | Fixed-dose combinations of antiviral compounds |
| WO2017023713A1 (en) * | 2015-08-04 | 2017-02-09 | Merck Sharp & Dohme Corp. | Methods for making pharmaceutical solid dosage forms of spray-dried dispersions |
| US10617675B2 (en) | 2015-08-06 | 2020-04-14 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| EP3359199A1 (en) | 2015-10-07 | 2018-08-15 | Sandoz AG | Solid pharmaceutical composition comprising amorphous sofosbuvir |
| WO2017072714A1 (en) | 2015-10-30 | 2017-05-04 | Lupin Limited | Stable ledipasvir premix and process of preparation thereof |
| JOP20170127A1 (ar) * | 2016-06-02 | 2017-12-02 | Gilead Pharmasset Llc | صيغة مشتركة مكونة من ثلاث مركبات مضادة للفيروسات |
| MX2019001771A (es) | 2016-08-12 | 2019-11-18 | Sandoz Ag | Composición farmacéutica sólida que comprende el sofosbuvir amorfo. |
| WO2018078536A1 (en) | 2016-10-26 | 2018-05-03 | Lupin Limited | Stable solid dispersion of sofosbuvir and process for preparation thereof |
| CN106727516A (zh) * | 2017-01-10 | 2017-05-31 | 山东省立医院 | 一种治疗丙型肝炎的药物组合物 |
| WO2019134971A1 (en) * | 2018-01-04 | 2019-07-11 | Sandoz Ag | Encapsulated particles comprising a pharmaceutically active ingredient |
| US11378965B2 (en) | 2018-11-15 | 2022-07-05 | Toyota Research Institute, Inc. | Systems and methods for controlling a vehicle based on determined complexity of contextual environment |
| CN113209087B (zh) * | 2020-02-05 | 2023-11-07 | 歌礼药业(浙江)有限公司 | 一种抑制冠状病毒的药物组合物及其用途 |
| IL303390A (en) | 2020-12-03 | 2023-08-01 | Battelle Memorial Institute | Compositions of polymer nanoparticles and DNA nanostructures and methods for non-viral transport |
| WO2022216977A1 (en) | 2021-04-07 | 2022-10-13 | Batelle Memorial Institute | Rapid design, build, test, and learn technologies for identifying and using non-viral carriers |
| NL2028762B1 (en) * | 2021-07-16 | 2023-01-23 | Seranovo Holding B V | Micelle-generating formulations for enhanced bioavailability |
| KR102842201B1 (ko) * | 2023-09-19 | 2025-08-06 | 한국해양과학기술원 | Lng 추진 선박용 이산화탄소 액화 시스템 및 방법 |
| WO2025072751A1 (en) | 2023-09-29 | 2025-04-03 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| AU2024393766A1 (en) | 2023-12-08 | 2026-06-18 | Battelle Memorial Institute | Use of dna origami nanostructures for molecular information based data storage systems |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL372247A1 (en) * | 2002-02-01 | 2005-07-11 | Pfizer Products Inc. | Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus |
| WO2005123076A2 (en) * | 2004-06-08 | 2005-12-29 | Vertex Pharmaceuticals, Inc. | Pharmaceutical compositions |
| JP2009530415A (ja) * | 2006-03-20 | 2009-08-27 | バーテックス ファーマシューティカルズ インコーポレイテッド | 医薬組成物 |
| US7964580B2 (en) * | 2007-03-30 | 2011-06-21 | Pharmasset, Inc. | Nucleoside phosphoramidate prodrugs |
| CN101827585A (zh) * | 2007-10-19 | 2010-09-08 | 雅培股份有限两合公司 | 含有n-芳基脲基化合物的固态分散体产品 |
| EP2323631A1 (en) * | 2008-08-07 | 2011-05-25 | Schering Corporation | Pharmaceutical formulations of an hcv protease inhibitor in a solid molecular dispersion |
| SMT201700121T1 (it) * | 2009-02-27 | 2017-03-08 | Janssen Pharmaceuticals Inc | Sale amorfo di un inibitore macrociclico di hcv |
| SG176015A1 (en) * | 2009-05-13 | 2011-12-29 | Gilead Sciences Inc | Antiviral compounds |
| EP2853531A3 (en) * | 2009-06-11 | 2015-08-12 | AbbVie Bahamas Ltd. | Antiviral compounds |
| US8937150B2 (en) * | 2009-06-11 | 2015-01-20 | Abbvie Inc. | Anti-viral compounds |
| US8415374B2 (en) * | 2009-10-12 | 2013-04-09 | Bristol-Myers Squibb Company | Combinations of hepatitis C virus inhibitors |
| NZ605440A (en) * | 2010-06-10 | 2014-05-30 | Abbvie Bahamas Ltd | Solid compositions comprising an hcv inhibitor |
| TW201446286A (zh) * | 2013-01-31 | 2014-12-16 | Gilead Pharmasset Llc | 抗病毒化合物之固態分散調製劑 |
-
2012
- 2012-12-18 JP JP2014550335A patent/JP5781706B2/ja not_active Expired - Fee Related
- 2012-12-18 DE DE212012000197.2U patent/DE212012000197U1/de not_active Expired - Lifetime
- 2012-12-18 WO PCT/US2012/070349 patent/WO2013101550A1/en not_active Ceased
- 2012-12-18 CN CN201280064815.5A patent/CN104010631B/zh active Active
- 2012-12-18 MX MX2014008008A patent/MX2014008008A/es unknown
- 2012-12-18 US US13/717,993 patent/US20130172239A1/en not_active Abandoned
- 2012-12-18 EP EP15156387.1A patent/EP2907505A3/en not_active Withdrawn
- 2012-12-18 CA CA2857339A patent/CA2857339C/en active Active
- 2012-12-18 EP EP12809070.1A patent/EP2797586A1/en not_active Withdrawn
- 2012-12-18 HK HK15101710.0A patent/HK1201186A1/xx unknown
-
2015
- 2015-07-14 JP JP2015140513A patent/JP2015227352A/ja active Pending
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