JP2015502327A5 - - Google Patents
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- Publication number
- JP2015502327A5 JP2015502327A5 JP2014548182A JP2014548182A JP2015502327A5 JP 2015502327 A5 JP2015502327 A5 JP 2015502327A5 JP 2014548182 A JP2014548182 A JP 2014548182A JP 2014548182 A JP2014548182 A JP 2014548182A JP 2015502327 A5 JP2015502327 A5 JP 2015502327A5
- Authority
- JP
- Japan
- Prior art keywords
- calcium phosphate
- range
- bone
- porous
- material according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000000988 bone and bone Anatomy 0.000 claims description 40
- 239000001506 calcium phosphate Substances 0.000 claims description 28
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 28
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 25
- 235000011010 calcium phosphates Nutrition 0.000 claims description 25
- 239000000463 material Substances 0.000 claims description 24
- 239000011148 porous material Substances 0.000 claims description 13
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 5
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 5
- 239000000316 bone substitute Substances 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 238000005245 sintering Methods 0.000 claims description 3
- 229910000391 tricalcium phosphate Inorganic materials 0.000 claims description 3
- 235000019731 tricalcium phosphate Nutrition 0.000 claims description 3
- 229940078499 tricalcium phosphate Drugs 0.000 claims description 3
- 239000013078 crystal Substances 0.000 claims 16
- 239000008187 granular material Substances 0.000 claims 13
- 239000007791 liquid phase Substances 0.000 claims 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 230000008468 bone growth Effects 0.000 claims 2
- 229910052791 calcium Inorganic materials 0.000 claims 2
- 239000011575 calcium Substances 0.000 claims 2
- 230000002950 deficient Effects 0.000 claims 2
- 238000007088 Archimedes method Methods 0.000 claims 1
- 238000004438 BET method Methods 0.000 claims 1
- 230000002051 biphasic effect Effects 0.000 claims 1
- 239000006185 dispersion Substances 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 claims 1
- 229910052753 mercury Inorganic materials 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000012071 phase Substances 0.000 claims 1
- 238000002459 porosimetry Methods 0.000 claims 1
- 230000002138 osteoinductive effect Effects 0.000 description 10
- 230000000278 osteoconductive effect Effects 0.000 description 6
- 239000007943 implant Substances 0.000 description 4
- 230000011164 ossification Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 2
- 229920000742 Cotton Polymers 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000004068 calcium phosphate ceramic Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 210000002901 mesenchymal stem cell Anatomy 0.000 description 1
- 239000002086 nanomaterial Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000011236 particulate material Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000009772 tissue formation Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201122405A GB201122405D0 (en) | 2011-12-23 | 2011-12-23 | Calcium phosphate material |
| GB1122405.2 | 2011-12-23 | ||
| PCT/GB2012/053160 WO2013093439A1 (en) | 2011-12-23 | 2012-12-17 | Calcium phosphate material |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015502327A JP2015502327A (ja) | 2015-01-22 |
| JP2015502327A5 true JP2015502327A5 (cg-RX-API-DMAC10.html) | 2017-08-17 |
| JP6396803B2 JP6396803B2 (ja) | 2018-09-26 |
Family
ID=45695045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014548182A Active JP6396803B2 (ja) | 2011-12-23 | 2012-12-17 | リン酸カルシウム材料 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9492585B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2794471B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP6396803B2 (cg-RX-API-DMAC10.html) |
| DK (1) | DK2794471T3 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2665848T3 (cg-RX-API-DMAC10.html) |
| GB (1) | GB201122405D0 (cg-RX-API-DMAC10.html) |
| HU (1) | HUE039094T2 (cg-RX-API-DMAC10.html) |
| NO (1) | NO2794471T3 (cg-RX-API-DMAC10.html) |
| PL (1) | PL2794471T3 (cg-RX-API-DMAC10.html) |
| PT (1) | PT2794471T (cg-RX-API-DMAC10.html) |
| SI (1) | SI2794471T1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2013093439A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI651103B (zh) | 2013-12-13 | 2019-02-21 | 萊特醫技股份有限公司 | 多相骨移植替代材料 |
| FR3021045B1 (fr) | 2014-05-16 | 2020-02-21 | Solvay Sa | Procede de production d'un reactif phosphocalcique, reactif obtenu et son utilisation |
| JP6663608B2 (ja) * | 2014-09-01 | 2020-03-13 | 国立大学法人九州大学 | 骨欠損再建治療用キット、医療用硬組織再建材、製品無機化合物の製造方法及び製品無機化合物 |
| JP6786227B2 (ja) * | 2015-02-27 | 2020-11-18 | 国立大学法人東北大学 | リン酸カルシウム合成装置及び合成方法 |
| JP2018531210A (ja) * | 2015-09-25 | 2018-10-25 | クリーン ワールド テクノロジーズ リミテッドＣｌｅａｎ Ｗｏｒｌｄ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｔｄ． | リン酸カルシウム組成物を生産すること |
| JP2017119230A (ja) * | 2015-12-28 | 2017-07-06 | Jnc株式会社 | 吸着剤およびその製造方法 |
| EP3338815A1 (en) * | 2016-12-23 | 2018-06-27 | Sunstar Suisse SA | Bone graft substitute |
| KR102461677B1 (ko) * | 2017-01-16 | 2022-10-31 | 위시본 | 골재생 물질 |
| JP6164628B1 (ja) * | 2017-03-30 | 2017-07-19 | 富田製薬株式会社 | 無水リン酸水素カルシウム、及びその製造方法 |
| JP6813716B1 (ja) * | 2017-12-14 | 2021-01-13 | ガイストリッヒ ファーマ アーゲー | 骨代替材料 |
| CA3083852A1 (en) | 2017-12-14 | 2019-06-20 | Geistlich Pharma Ag | Biphasic calcium phosphate/hydroxyapatite bone substitute material |
| CN110446548B (zh) * | 2018-03-06 | 2022-10-11 | 贝赛尔思有限公司 | 磷酸钙的制备方法、及包含通过其获得的磷酸钙的有害气体及恶臭去除用组合物 |
| WO2020249714A1 (en) * | 2019-06-14 | 2020-12-17 | Geistlich Pharma Ag | Collagen matrix or granulate blend of bone substitute material |
| CN114761048B (zh) | 2019-06-14 | 2023-05-02 | 盖斯特里希医药公司 | 骨替代材料的胶原基质或颗粒共混物 |
| US11498880B2 (en) | 2019-07-26 | 2022-11-15 | Warsaw Orthopedic, Inc. | Calcium phosphate granules and methods of making them |
| GB202012350D0 (en) | 2020-08-07 | 2020-09-23 | Sirakoss Ltd | Method of producing calcium-deficient silicate-substituted calcium phosphate apatite |
| KR102895796B1 (ko) * | 2023-06-30 | 2025-12-04 | 오스템임플란트 주식회사 | 저결정성 칼슘인산염계 항균 골이식재 및 그 제조방법 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0376331A3 (en) * | 1988-12-29 | 1991-03-13 | Asahi Kogaku Kogyo Kabushiki Kaisha | Slow release drug delivery granules and process for production thereof |
| US6013591A (en) | 1997-01-16 | 2000-01-11 | Massachusetts Institute Of Technology | Nanocrystalline apatites and composites, prostheses incorporating them, and method for their production |
| GB0900269D0 (en) | 2009-01-08 | 2009-02-11 | Univ Aberdeen | Silicate-substituted hydroxyapatite |
| DE102009039665A1 (de) | 2009-09-02 | 2011-03-03 | Aap Biomaterials Gmbh | Hydroxylapatitmaterial sowie Verfahren zu dessen Herstellung |
| US20110144763A1 (en) * | 2009-10-29 | 2011-06-16 | Prosidyan Inc. | Dynamic bioactive bone graft material having an engineered porosity |
-
2011
- 2011-12-23 GB GB201122405A patent/GB201122405D0/en not_active Ceased
-
2012
- 2012-12-17 US US14/367,145 patent/US9492585B2/en active Active
- 2012-12-17 SI SI201231267T patent/SI2794471T1/en unknown
- 2012-12-17 JP JP2014548182A patent/JP6396803B2/ja active Active
- 2012-12-17 PT PT128098431T patent/PT2794471T/pt unknown
- 2012-12-17 DK DK12809843.1T patent/DK2794471T3/en active
- 2012-12-17 EP EP12809843.1A patent/EP2794471B1/en active Active
- 2012-12-17 NO NO12809843A patent/NO2794471T3/no unknown
- 2012-12-17 WO PCT/GB2012/053160 patent/WO2013093439A1/en not_active Ceased
- 2012-12-17 HU HUE12809843A patent/HUE039094T2/hu unknown
- 2012-12-17 PL PL12809843T patent/PL2794471T3/pl unknown
- 2012-12-17 ES ES12809843.1T patent/ES2665848T3/es active Active
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