JP2015221379A - 被験者の眼球に電磁放射を送達するシステム - Google Patents
被験者の眼球に電磁放射を送達するシステム Download PDFInfo
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- JP2015221379A JP2015221379A JP2015176686A JP2015176686A JP2015221379A JP 2015221379 A JP2015221379 A JP 2015221379A JP 2015176686 A JP2015176686 A JP 2015176686A JP 2015176686 A JP2015176686 A JP 2015176686A JP 2015221379 A JP2015221379 A JP 2015221379A
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- 230000005670 electromagnetic radiation Effects 0.000 title claims abstract description 126
- 210000005252 bulbus oculi Anatomy 0.000 title claims abstract description 49
- 210000000744 eyelid Anatomy 0.000 claims abstract description 62
- 238000001126 phototherapy Methods 0.000 claims abstract description 40
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 claims abstract description 28
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 claims abstract description 15
- 230000009286 beneficial effect Effects 0.000 claims abstract description 15
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229960003987 melatonin Drugs 0.000 claims abstract description 15
- 229940076279 serotonin Drugs 0.000 claims abstract description 14
- 230000005855 radiation Effects 0.000 claims description 154
- 210000001508 eye Anatomy 0.000 claims description 27
- 230000008859 change Effects 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 12
- 230000007958 sleep Effects 0.000 abstract description 10
- 230000027288 circadian rhythm Effects 0.000 abstract description 3
- 208000019022 Mood disease Diseases 0.000 abstract description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 2
- 208000019116 sleep disease Diseases 0.000 abstract description 2
- 208000012672 seasonal affective disease Diseases 0.000 abstract 2
- 208000020685 sleep-wake disease Diseases 0.000 abstract 1
- 238000005286 illumination Methods 0.000 description 18
- 239000000463 material Substances 0.000 description 17
- 230000005540 biological transmission Effects 0.000 description 10
- 238000004891 communication Methods 0.000 description 8
- 208000011580 syndromic disease Diseases 0.000 description 4
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
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- 230000001939 inductive effect Effects 0.000 description 3
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- 230000008569 process Effects 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 238000001429 visible spectrum Methods 0.000 description 3
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 2
- 230000001932 seasonal effect Effects 0.000 description 2
- 0 CC(C1C)*(*)C2S(C)C2(*)/C1=C/C Chemical compound CC(C1C)*(*)C2S(C)C2(*)/C1=C/C 0.000 description 1
- 208000027534 Emotional disease Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
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- 208000035475 disorder Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
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- 230000000977 initiatory effect Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0618—Psychological treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
- A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
- A61N2005/0645—Applicators worn by the patient
- A61N2005/0647—Applicators worn by the patient the applicator adapted to be worn on the head
- A61N2005/0648—Applicators worn by the patient the applicator adapted to be worn on the head the light being directed to the eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
- A61N2005/0653—Organic light emitting diodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Social Psychology (AREA)
- Developmental Disabilities (AREA)
- Child & Adolescent Psychology (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Radiation-Therapy Devices (AREA)
Abstract
【解決手段】 光線療法が、システム及び/又は方法を使用して被験者に提供される。光線療法は、(例えば、被験者が眠っている時等)被験者の眼瞼が閉じている間の、被験者の眼瞼の下にある被験者の眼球への電磁放射の投与を含む。治療上有益な様式で被験者の体内のメラトニン及び/又はセロトニンレベルに影響を与えるよう、光線療法アルゴリズムを設計することができる。例えば、光線療法アルゴリズムは、睡眠障害及び/若しくは気分障害(例えば、季節性感情障害、季節に関係しないうつ状態、概日リズムの混乱等)、又は、体内のメラトニン及び/又はセロトニンレベルに対する制御で治療可能な他の障害のうち1又は複数の障害を治療するために、メラトニン及び/又はセロトニンレベルに影響を与えるよう設計することができる。
【選択図】 図1
Description
Claims (4)
- 被験者に光線療法を提供するよう構成されるシステムであって、
使用中、被験者の眼球と眼瞼との間に少なくとも部分的に配置されたままであるよう構成される放射導入モジュールであり、前記被験者が眠っている間に前記被験者の眼瞼の下にある前記被験者の眼球に電磁放射を送達して、前記被験者に光線療法を提供するよう構成される放射導入モジュール、及び
治療上有益な様式でメラトニン及び/又はセロトニンレベルに影響を与えるよう、前記被験者の眼球に対する前記電磁放射の導入を制御するよう構成されるプロセッサ、
を含み、
前記放射導入モジュールが、
使用中、前記被験者の眼瞼と眼球との間に置かれるよう構成される本体部分、並びに
使用中、前記本体部分のうち、前記被験者の眼球とは反対の側に形成されるガイド部分であり、前記被験者が眠っている時に前記被験者の上の眼瞼と下の眼瞼との間に位置するよう、及び、光線療法の間に前記被験者の眼球に送達するよう、前記眼瞼の外部からの電磁放射を前記本体部分まで導くよう構成されるガイド部分、
を含む、システム。 - 前記放射導入モジュールが前記被験者の眼内に取り付けられ、さらに、前記被験者が眠っている場合に前記被験者の眼球と眼瞼との間で前記放射導入モジュールによって保持される1又は複数の放射源をさらに含み、前記1又は複数の放射源に電力が供給されて、前記放射導入モジュールによって前記被験者の眼球に送達される前記電磁放射を放つ、請求項1に記載のシステム。
- 前記放射導入モジュールは、前記被験者の眼瞼を通過した電磁放射を受けるよう、前記受けた電磁放射の波長を治療上有益な波長に変えるよう、及び、前記治療上有益な波長を有する前記電磁放射を前記被験者の眼球に向けるよう構成される、請求項1に記載のシステム。
- 前記放射導入モジュールは、前記被験者の眼球の上に位置するレンズを含み、前記レンズは、前記被験者の眼瞼が開いている場合に、所定の波長の範囲内の電磁放射が前記被験者の眼球に到達するのを選択的に防ぐよう構成される、請求項1に記載のシステム。
Applications Claiming Priority (2)
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US17239109P | 2009-04-24 | 2009-04-24 | |
US61/172,391 | 2009-04-24 |
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JP2012506603A Division JP5808318B2 (ja) | 2009-04-24 | 2010-03-15 | 被験者の眼球に電磁放射を送達するシステム |
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JP2015221379A true JP2015221379A (ja) | 2015-12-10 |
JP6050451B2 JP6050451B2 (ja) | 2016-12-21 |
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JP2012506603A Active JP5808318B2 (ja) | 2009-04-24 | 2010-03-15 | 被験者の眼球に電磁放射を送達するシステム |
JP2015176686A Active JP6050451B2 (ja) | 2009-04-24 | 2015-09-08 | 被験者の眼球に電磁放射を送達するシステム |
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JP2012506603A Active JP5808318B2 (ja) | 2009-04-24 | 2010-03-15 | 被験者の眼球に電磁放射を送達するシステム |
Country Status (8)
Country | Link |
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US (1) | US10357663B2 (ja) |
EP (1) | EP2421608B1 (ja) |
JP (2) | JP5808318B2 (ja) |
CN (1) | CN102413874B (ja) |
AU (1) | AU2010240636A1 (ja) |
BR (1) | BRPI1007738A2 (ja) |
RU (1) | RU2567263C2 (ja) |
WO (1) | WO2010122434A1 (ja) |
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- 2010-03-15 RU RU2011147585/14A patent/RU2567263C2/ru active
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- 2010-03-15 JP JP2012506603A patent/JP5808318B2/ja active Active
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Publication number | Publication date |
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JP5808318B2 (ja) | 2015-11-10 |
AU2010240636A1 (en) | 2011-12-15 |
JP2012524592A (ja) | 2012-10-18 |
CN102413874B (zh) | 2015-09-30 |
BRPI1007738A2 (pt) | 2016-12-27 |
EP2421608B1 (en) | 2013-07-10 |
CN102413874A (zh) | 2012-04-11 |
RU2567263C2 (ru) | 2015-11-10 |
WO2010122434A1 (en) | 2010-10-28 |
EP2421608A1 (en) | 2012-02-29 |
RU2011147585A (ru) | 2013-05-27 |
JP6050451B2 (ja) | 2016-12-21 |
US10357663B2 (en) | 2019-07-23 |
US20120041520A1 (en) | 2012-02-16 |
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