JP2015134824A5 - - Google Patents
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- Publication number
- JP2015134824A5 JP2015134824A5 JP2015090887A JP2015090887A JP2015134824A5 JP 2015134824 A5 JP2015134824 A5 JP 2015134824A5 JP 2015090887 A JP2015090887 A JP 2015090887A JP 2015090887 A JP2015090887 A JP 2015090887A JP 2015134824 A5 JP2015134824 A5 JP 2015134824A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- vitreous
- cornea
- pharmaceutically acceptable
- therapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 description 4
- 210000001742 aqueous humor Anatomy 0.000 description 2
- 210000004087 cornea Anatomy 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940124597 therapeutic agent Drugs 0.000 description 2
- 210000004127 vitreous body Anatomy 0.000 description 2
- 210000002159 anterior chamber Anatomy 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 210000003161 choroid Anatomy 0.000 description 1
- 210000004240 ciliary body Anatomy 0.000 description 1
- 210000000795 conjunctiva Anatomy 0.000 description 1
- 210000000695 crystalline len Anatomy 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 210000000554 iris Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 210000001525 retina Anatomy 0.000 description 1
- 210000003786 sclera Anatomy 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26896109P | 2009-06-17 | 2009-06-17 | |
| US61/268,961 | 2009-06-17 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516311A Division JP5822826B2 (ja) | 2009-06-17 | 2010-06-17 | Sap変異体及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015134824A JP2015134824A (ja) | 2015-07-27 |
| JP2015134824A5 true JP2015134824A5 (enExample) | 2017-03-16 |
| JP6124943B2 JP6124943B2 (ja) | 2017-05-10 |
Family
ID=43354870
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516311A Active JP5822826B2 (ja) | 2009-06-17 | 2010-06-17 | Sap変異体及びその使用 |
| JP2015090887A Active JP6124943B2 (ja) | 2009-06-17 | 2015-04-27 | Sap変異体及びその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516311A Active JP5822826B2 (ja) | 2009-06-17 | 2010-06-17 | Sap変異体及びその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8329659B2 (enExample) |
| EP (2) | EP2987803B1 (enExample) |
| JP (2) | JP5822826B2 (enExample) |
| AU (1) | AU2010262847B2 (enExample) |
| CA (2) | CA2765394C (enExample) |
| DK (2) | DK2987803T3 (enExample) |
| ES (2) | ES2552793T3 (enExample) |
| HU (2) | HUE028067T2 (enExample) |
| PL (1) | PL2987803T3 (enExample) |
| WO (1) | WO2010148234A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9884899B2 (en) * | 2007-07-06 | 2018-02-06 | Promedior, Inc. | Methods for treating fibrosis using CRP antagonists |
| JP5980508B2 (ja) * | 2009-03-11 | 2016-08-31 | プロメディオール, インコーポレイテッド | 自己免疫障害に対する処置方法 |
| WO2010104959A1 (en) * | 2009-03-11 | 2010-09-16 | Promedior, Inc. | Treatment and diagnostic methods for hypersensitive disorders |
| UA110323C2 (en) * | 2009-06-04 | 2015-12-25 | Promedior Inc | Derivative of serum amyloid p and their receipt and application |
| DK2987803T3 (en) * | 2009-06-17 | 2018-12-17 | Promedior Inc | SAP variants and their application |
| US20150087576A1 (en) * | 2011-12-14 | 2015-03-26 | The Texas A&M University System | Compositions associated with and methods of managing neutrophil movement using serum amyloid p (sap) |
| WO2013096847A1 (en) | 2011-12-21 | 2013-06-27 | Promedior, Inc. | Serum amyloid p-antibody fusion proteins |
| ES2784234T3 (es) | 2013-10-08 | 2020-09-23 | Promedior Inc | Métodos para el tratamiento de cánceres fibróticos |
| FR3012453B1 (fr) | 2013-10-31 | 2015-11-13 | Lab Francais Du Fractionnement | Proteine chimerique dans le traitement de l’amylose |
| AU2016248317A1 (en) * | 2015-04-15 | 2017-11-09 | Promedior, Inc. | Methods for treating myeloproliferative disorders |
| CN108114001B (zh) * | 2017-12-23 | 2023-05-30 | 中国科学院海洋研究所 | 一种诱导海产双壳贝类产卵的诱导剂及其应用方法 |
| EP3669885A1 (en) * | 2018-12-20 | 2020-06-24 | Humanitas Mirasole S.p.A. | Use of sap for the treatment of eurotiomycetes fungi infections |
| AU2021368272A1 (en) * | 2020-11-02 | 2023-06-08 | Attralus, Inc. | Sap fc fusion proteins and methods of use |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5023A (en) * | 1847-03-20 | Stocking-loom | ||
| GB1562244A (en) | 1976-11-11 | 1980-03-05 | Lock P M | Wound dressing materials |
| GB1594389A (en) | 1977-06-03 | 1981-07-30 | Max Planck Gesellschaft | Dressing material for wounds |
| GB8516081D0 (en) | 1985-06-25 | 1985-07-31 | Ciba Geigy Ag | Assay & purification of amyloid components |
| US6071517A (en) | 1986-07-07 | 2000-06-06 | Medarex, Inc. | Bispecific heteroantibodies with dual effector functions |
| DE3853219T2 (de) | 1987-11-20 | 1995-06-29 | Kanegafuchi Chemical Ind | Methode zur Entfernung von Serum-Amyloid-Protein. |
| US7070994B2 (en) | 1988-03-21 | 2006-07-04 | Oxford Biomedica (Uk) Ltd. | Packaging cells |
| US5272258A (en) | 1989-06-29 | 1993-12-21 | Rush-Presbyterian-St. Luke's Medical Center | Monoclonal antibodies to C-reactive protein |
| US5092876A (en) | 1989-08-30 | 1992-03-03 | The United States Of America As Represented By The Department Of Health And Human Services | Cell attachment peptides derived from amyloid P component |
| AU2158292A (en) | 1991-05-31 | 1993-01-08 | New England Deaconess Hospital Corporation | Cea-binding proteins and methods for their isolation and use |
| US5591709A (en) | 1991-08-30 | 1997-01-07 | Life Medical Sciences, Inc. | Compositions and methods for treating wounds |
| US5654186A (en) | 1993-02-26 | 1997-08-05 | The Picower Institute For Medical Research | Blood-borne mesenchymal cells |
| US5804446A (en) | 1993-02-26 | 1998-09-08 | The Picower Institute For Medical Research | Blood-borne mesenchymal cells |
| US6054121A (en) | 1993-02-26 | 2000-04-25 | The Picower Institute For Medical Research | Modulation of immune responses in blood-borne mesenchymal cells |
| WO1994027640A1 (en) | 1993-05-27 | 1994-12-08 | The Regents Of The University Of Michigan | Method of treatment and prevention of immune complex-induced lung injury |
| US5698589A (en) | 1993-06-01 | 1997-12-16 | International Medical Innovations, Inc. | Water-based topical cream containing nitroglycerin and method of preparation and use thereof |
| GB9317120D0 (en) * | 1993-08-17 | 1993-09-29 | Royal Postgrad Med School | Human serum amyloid p component |
| US5981470A (en) | 1994-06-07 | 1999-11-09 | The University Of Birmingham | Uterine fibroid treatment |
| US5989811A (en) | 1994-09-29 | 1999-11-23 | Urocor, Inc. | Sextant core biopsy predictive mechanism for non-organ confined disease status |
| US5750345A (en) | 1995-10-31 | 1998-05-12 | Evanston Hospital Corporation | Detection of human α-thalassemia mutations and their use as predictors of blood-related disorders |
| EP0915707B1 (en) | 1996-01-25 | 2002-10-30 | Profylakse ApS | Pharmaceutical composition comprising serum amyloid p component for prophylactic or therapeutic treatment of virus infections and a kit for detecting binding of compositions to virus components |
| US6365570B1 (en) | 1997-10-10 | 2002-04-02 | Universiteit Utrecht | Pharmaceutical and diagnostic use of Serum Amyloid P component |
| CN1307590A (zh) | 1998-02-17 | 2001-08-08 | 米德列斯公司 | 用fc受体配基治疗和诊断巨噬细胞介导的疾病 |
| ES2220257T1 (es) | 1998-03-11 | 2004-12-16 | Kabushiki Kaisha Soken | Agentes normalizadores para la piel. |
| JPH11319542A (ja) | 1998-05-08 | 1999-11-24 | Tokuyama Corp | 超薄層の製造方法 |
| US6660843B1 (en) * | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| US6600019B2 (en) | 2000-01-06 | 2003-07-29 | Curagen Corporation | Polypeptides and nucleic acids encoding same |
| EP1267795A1 (en) | 2000-03-30 | 2003-01-02 | Brennen Medical Inc. | Anti-microbial and immunostimulating composition |
| US20040068095A1 (en) | 2001-03-14 | 2004-04-08 | Shimkets Richard A. | Novel human proteins, polynucleotides encoding them and methods of using the same |
| US7713705B2 (en) | 2002-12-24 | 2010-05-11 | Biosite, Inc. | Markers for differential diagnosis and methods of use thereof |
| US6872541B2 (en) | 2001-07-25 | 2005-03-29 | Coulter International Corp. | Method and compositions for analysis of pentraxin receptors as indicators of disease |
| US6537811B1 (en) | 2001-08-01 | 2003-03-25 | Isis Pharmaceuticals, Inc. | Antisense inhibition of SAP-1 expression |
| US20030199442A1 (en) | 2001-10-09 | 2003-10-23 | Alsobrook John P. | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| US7022476B2 (en) | 2002-02-26 | 2006-04-04 | New York Society For Ruptured And Crippled Maintaining The Hospital For Special Surgery | Human FcγRIIB gene polymorphisms for assessing development of systemic lupus erythematosus and compositions for use thereof |
| GB0211136D0 (en) | 2002-05-15 | 2002-06-26 | Univ London | Treatment and prevention of tissue damage |
| NZ536555A (en) | 2002-05-17 | 2007-03-30 | Novartis Ag | Pharmaceutical composition comprising a renin inhibitor, a calcium channel blocker and a diuretic |
| GB0216648D0 (en) | 2002-07-18 | 2002-08-28 | Lonza Biologics Plc | Method of expressing recombinant protein in CHO cells |
| JP4459810B2 (ja) | 2002-08-14 | 2010-04-28 | マクロジェニクス,インコーポレーテッド | FcγRIIB特異的抗体とその利用法 |
| US8946387B2 (en) | 2002-08-14 | 2015-02-03 | Macrogenics, Inc. | FcγRIIB specific antibodies and methods of use thereof |
| US20050260213A1 (en) | 2004-04-16 | 2005-11-24 | Scott Koenig | Fcgamma-RIIB-specific antibodies and methods of use thereof |
| US8012472B2 (en) | 2002-12-23 | 2011-09-06 | William Marsh Rice University | Compositions and methods for suppressing fibrocytes |
| US7763256B2 (en) | 2002-12-23 | 2010-07-27 | William Marsh Rice University | Compositions and methods for suppressing fibrocytes and for detecting fibrocyte differentiation |
| JP4922560B2 (ja) | 2002-12-23 | 2012-04-25 | ウイリアム、マーシュ、ライス、ユーニヴァーサティ | 線維細胞への分化の検出方法、線維症を抑制する組成物および方法 |
| CA2517037A1 (en) | 2003-02-27 | 2004-09-10 | Theravision Gmbh | Method for reducing levels of c-reactive protein |
| CA2565874C (en) | 2004-05-10 | 2017-10-03 | Macrogenics, Inc. | Humanized fc.gamma.riib-specific antibodies and methods of use thereof |
| US7378504B2 (en) | 2004-06-03 | 2008-05-27 | Medarex, Inc. | Human monoclonal antibodies to Fc gamma receptor I (CD64) |
| WO2006002930A2 (en) | 2004-06-30 | 2006-01-12 | Friedrich-Alexander- Universitaet Erlangen- Nuernberg | FcϜRIIa POLYMORPHISM AND ITS USE IN DIAGNOSIS |
| BRPI0515589A (pt) | 2004-09-02 | 2008-07-29 | Genentech Inc | polipeptìdeos ou anticorpos de ligação de antìgeno isolado, anticorpo isolado, método para regular de forma negativa a atividade de fc(gama)riib, métodos de tratamento, anticorpos biespecìficos isolados, métodos de inibição de uma resposta imune, de supressão na liberação de histamina, de ativação de fc(gama)riib, de inibição da expressão do receptor fc(épsilon)ri, composição e kit |
| US7553653B2 (en) * | 2004-09-17 | 2009-06-30 | Biomarin Pharmaceutical Inc. | Variants and chemically-modified variants of phenylalanine ammonia-lyase |
| US7405302B2 (en) | 2005-10-11 | 2008-07-29 | Amira Pharmaceuticals, Inc. | 5-lipoxygenase-activating protein (FLAP) inhibitors |
| CA2625403A1 (en) | 2005-10-17 | 2007-04-26 | Institute For System Biology | Tissue-and serum-derived glycoproteins and methods of their use |
| EP2505209A1 (en) | 2006-06-26 | 2012-10-03 | MacroGenics, Inc. | Fcgamma-RIIB-specific antibodies and methods of the use thereof |
| US8247370B2 (en) | 2006-12-04 | 2012-08-21 | Promedior, Inc. | Conjoint therapy for treating fibrotic diseases |
| EP2185581B1 (en) * | 2007-07-06 | 2015-09-02 | Promedior, Inc. | Methods and compositions useful in the treatment of mucositis |
| US9884899B2 (en) * | 2007-07-06 | 2018-02-06 | Promedior, Inc. | Methods for treating fibrosis using CRP antagonists |
| US8497243B2 (en) | 2007-07-06 | 2013-07-30 | Promedior, Inc. | Methods and compositions useful in the treatment of mucositis |
| JP5980508B2 (ja) | 2009-03-11 | 2016-08-31 | プロメディオール, インコーポレイテッド | 自己免疫障害に対する処置方法 |
| WO2010104959A1 (en) | 2009-03-11 | 2010-09-16 | Promedior, Inc. | Treatment and diagnostic methods for hypersensitive disorders |
| AU2010232591A1 (en) | 2009-04-01 | 2011-11-03 | Promedior, Inc. | Pulmonary and nasal delivery of serum amyloid P |
| UA110323C2 (en) * | 2009-06-04 | 2015-12-25 | Promedior Inc | Derivative of serum amyloid p and their receipt and application |
| DK2987803T3 (en) * | 2009-06-17 | 2018-12-17 | Promedior Inc | SAP variants and their application |
-
2010
- 2010-06-17 DK DK15181052.0T patent/DK2987803T3/en active
- 2010-06-17 PL PL15181052T patent/PL2987803T3/pl unknown
- 2010-06-17 ES ES10790213.2T patent/ES2552793T3/es active Active
- 2010-06-17 EP EP15181052.0A patent/EP2987803B1/en active Active
- 2010-06-17 CA CA2765394A patent/CA2765394C/en active Active
- 2010-06-17 AU AU2010262847A patent/AU2010262847B2/en active Active
- 2010-06-17 HU HUE10790213A patent/HUE028067T2/en unknown
- 2010-06-17 WO PCT/US2010/039043 patent/WO2010148234A1/en not_active Ceased
- 2010-06-17 EP EP10790213.2A patent/EP2443144B1/en active Active
- 2010-06-17 JP JP2012516311A patent/JP5822826B2/ja active Active
- 2010-06-17 ES ES15181052T patent/ES2708823T3/es active Active
- 2010-06-17 CA CA3083911A patent/CA3083911C/en active Active
- 2010-06-17 DK DK10790213.2T patent/DK2443144T3/en active
- 2010-06-17 HU HUE15181052A patent/HUE041034T2/hu unknown
- 2010-06-17 US US12/817,535 patent/US8329659B2/en active Active
-
2012
- 2012-11-06 US US13/669,937 patent/US9556246B2/en active Active
-
2015
- 2015-04-27 JP JP2015090887A patent/JP6124943B2/ja active Active
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