JP2015101540A5 - - Google Patents
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- Publication number
- JP2015101540A5 JP2015101540A5 JP2013240549A JP2013240549A JP2015101540A5 JP 2015101540 A5 JP2015101540 A5 JP 2015101540A5 JP 2013240549 A JP2013240549 A JP 2013240549A JP 2013240549 A JP2013240549 A JP 2013240549A JP 2015101540 A5 JP2015101540 A5 JP 2015101540A5
- Authority
- JP
- Japan
- Prior art keywords
- enzyme
- measured
- skin
- enzyme activity
- wrinkles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000004190 Enzymes Human genes 0.000 description 16
- 108090000790 Enzymes Proteins 0.000 description 16
- 230000000694 effects Effects 0.000 description 9
- 210000003491 skin Anatomy 0.000 description 9
- 239000011148 porous material Substances 0.000 description 7
- 230000037303 wrinkles Effects 0.000 description 5
- 102000006746 NADH Dehydrogenase Human genes 0.000 description 4
- 108010086428 NADH Dehydrogenase Proteins 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- CCBICDLNWJRFPO-UHFFFAOYSA-N 2,6-dichloroindophenol Chemical compound C1=CC(O)=CC=C1N=C1C=C(Cl)C(=O)C(Cl)=C1 CCBICDLNWJRFPO-UHFFFAOYSA-N 0.000 description 2
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 2
- 102000004958 Caspase-14 Human genes 0.000 description 2
- 108090001132 Caspase-14 Proteins 0.000 description 2
- 102000016938 Catalase Human genes 0.000 description 2
- 108010053835 Catalase Proteins 0.000 description 2
- 102100034868 Kallikrein-5 Human genes 0.000 description 2
- 101710176223 Kallikrein-5 Proteins 0.000 description 2
- 230000001678 irradiating effect Effects 0.000 description 2
- 102100034289 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Human genes 0.000 description 1
- 102000002812 Heat-Shock Proteins Human genes 0.000 description 1
- 108010004889 Heat-Shock Proteins Proteins 0.000 description 1
- 101000641031 Homo sapiens Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Proteins 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 description 1
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013240549A JP6253361B2 (ja) | 2013-11-21 | 2013-11-21 | 皮膚外用剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013240549A JP6253361B2 (ja) | 2013-11-21 | 2013-11-21 | 皮膚外用剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015101540A JP2015101540A (ja) | 2015-06-04 |
| JP2015101540A5 true JP2015101540A5 (enExample) | 2016-10-13 |
| JP6253361B2 JP6253361B2 (ja) | 2017-12-27 |
Family
ID=53377548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013240549A Active JP6253361B2 (ja) | 2013-11-21 | 2013-11-21 | 皮膚外用剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6253361B2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6630066B2 (ja) * | 2015-06-10 | 2020-01-15 | ポーラ化成工業株式会社 | 酵素活性化剤 |
| WO2017023690A1 (en) * | 2015-07-31 | 2017-02-09 | Exoceuticals, Inc. | Exosome compositions and methods for preparation and use thereof for regulating and conditioning skin and hair |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3206894B2 (ja) * | 1996-07-25 | 2001-09-10 | 理化学研究所 | 酵素を熱活性化する方法 |
| JP2002234828A (ja) * | 2001-02-07 | 2002-08-23 | Nikko Seiyaku Kk | 美白化粧料 |
| JP4562536B2 (ja) * | 2005-01-27 | 2010-10-13 | 株式会社ノエビア | 皮膚外用剤 |
| JP6185372B2 (ja) * | 2013-11-21 | 2017-08-23 | ポーラ化成工業株式会社 | 皮膚外用剤 |
-
2013
- 2013-11-21 JP JP2013240549A patent/JP6253361B2/ja active Active
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