JP2015091866A5 - - Google Patents
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- Publication number
- JP2015091866A5 JP2015091866A5 JP2015007494A JP2015007494A JP2015091866A5 JP 2015091866 A5 JP2015091866 A5 JP 2015091866A5 JP 2015007494 A JP2015007494 A JP 2015007494A JP 2015007494 A JP2015007494 A JP 2015007494A JP 2015091866 A5 JP2015091866 A5 JP 2015091866A5
- Authority
- JP
- Japan
- Prior art keywords
- concentrate
- igg
- blood group
- group
- content
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940027941 immunoglobulin g Drugs 0.000 claims 14
- 239000008280 blood Substances 0.000 claims 12
- 210000004369 blood Anatomy 0.000 claims 12
- 239000012141 concentrate Substances 0.000 claims 12
- 238000000034 method Methods 0.000 claims 9
- 150000002482 oligosaccharides Polymers 0.000 claims 5
- 102000009027 Albumins Human genes 0.000 claims 4
- 108010088751 Albumins Proteins 0.000 claims 4
- 241000700605 Viruses Species 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 238000004587 chromatography analysis Methods 0.000 claims 3
- 239000003381 stabilizer Substances 0.000 claims 3
- 150000004043 trisaccharides Chemical class 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 2
- 102000003505 Myosin Human genes 0.000 claims 2
- 108060008487 Myosin Proteins 0.000 claims 2
- MBLBDJOUHNCFQT-UHFFFAOYSA-N N-acetyl-D-galactosamine Natural products CC(=O)NC(C=O)C(O)C(O)C(O)CO MBLBDJOUHNCFQT-UHFFFAOYSA-N 0.000 claims 2
- -1 dinitrophenyl group Chemical group 0.000 claims 2
- 238000001914 filtration Methods 0.000 claims 2
- 230000002779 inactivation Effects 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 150000005846 sugar alcohols Chemical class 0.000 claims 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 1
- 239000004471 Glycine Substances 0.000 claims 1
- SHZGCJCMOBCMKK-DHVFOXMCSA-N L-fucopyranose Chemical compound C[C@@H]1OC(O)[C@@H](O)[C@H](O)[C@@H]1O SHZGCJCMOBCMKK-DHVFOXMCSA-N 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- OVRNDRQMDRJTHS-CBQIKETKSA-N N-Acetyl-D-Galactosamine Chemical compound CC(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@H](O)[C@@H]1O OVRNDRQMDRJTHS-CBQIKETKSA-N 0.000 claims 1
- OVRNDRQMDRJTHS-KEWYIRBNSA-N N-acetyl-D-galactosamine Chemical compound CC(=O)N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O OVRNDRQMDRJTHS-KEWYIRBNSA-N 0.000 claims 1
- XNBZPOHDTUWNMW-VAVSLJLZSA-N alpha-L-Fuc-(1->2)-[alpha-D-Gal-(1->3)]-beta-D-Gal Chemical compound O[C@H]1[C@H](O)[C@H](O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](O[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@@H](CO)O[C@H]1O XNBZPOHDTUWNMW-VAVSLJLZSA-N 0.000 claims 1
- 239000003957 anion exchange resin Substances 0.000 claims 1
- 238000013375 chromatographic separation Methods 0.000 claims 1
- 239000000356 contaminant Substances 0.000 claims 1
- 238000011049 filling Methods 0.000 claims 1
- 238000005194 fractionation Methods 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 238000002386 leaching Methods 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 239000000594 mannitol Substances 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 238000001728 nano-filtration Methods 0.000 claims 1
- 239000002736 nonionic surfactant Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 230000001376 precipitating effect Effects 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 239000000600 sorbitol Substances 0.000 claims 1
- 238000011146 sterile filtration Methods 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 238000000108 ultra-filtration Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0513311A FR2895263B1 (fr) | 2005-12-26 | 2005-12-26 | Concentre d'immunoglobines g (lg) appauvri en anticorps anti-a et anti-b, et en igg polyreactives |
| FR0513311 | 2005-12-26 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008548014A Division JP5726403B2 (ja) | 2005-12-26 | 2006-12-26 | 抗Ａおよび抗Ｂ抗体、ならびに多反応性ＩｇＧが減少した免疫グロブリンＧ（ＩｇＧ）濃縮物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015091866A JP2015091866A (ja) | 2015-05-14 |
| JP2015091866A5 true JP2015091866A5 (https=) | 2015-10-08 |
| JP5944543B2 JP5944543B2 (ja) | 2016-07-05 |
Family
ID=36956126
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008548014A Active JP5726403B2 (ja) | 2005-12-26 | 2006-12-26 | 抗Ａおよび抗Ｂ抗体、ならびに多反応性ＩｇＧが減少した免疫グロブリンＧ（ＩｇＧ）濃縮物 |
| JP2013036624A Pending JP2013151507A (ja) | 2005-12-26 | 2013-02-27 | 抗Ａおよび抗Ｂ抗体、ならびに多反応性ＩｇＧが減少した免疫グロブリンＧ（ＩｇＧ）濃縮物 |
| JP2015007494A Active JP5944543B2 (ja) | 2005-12-26 | 2015-01-19 | 抗Ａおよび抗Ｂ抗体、ならびに多反応性ＩｇＧが減少した免疫グロブリンＧ（ＩｇＧ）濃縮物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008548014A Active JP5726403B2 (ja) | 2005-12-26 | 2006-12-26 | 抗Ａおよび抗Ｂ抗体、ならびに多反応性ＩｇＧが減少した免疫グロブリンＧ（ＩｇＧ）濃縮物 |
| JP2013036624A Pending JP2013151507A (ja) | 2005-12-26 | 2013-02-27 | 抗Ａおよび抗Ｂ抗体、ならびに多反応性ＩｇＧが減少した免疫グロブリンＧ（ＩｇＧ）濃縮物 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8153382B2 (https=) |
| EP (3) | EP1968634B1 (https=) |
| JP (3) | JP5726403B2 (https=) |
| KR (1) | KR101250095B1 (https=) |
| CN (3) | CN102921004A (https=) |
| AU (1) | AU2006334278B2 (https=) |
| BR (1) | BRPI0620600B1 (https=) |
| CA (1) | CA2634997C (https=) |
| DK (2) | DK1968634T3 (https=) |
| ES (2) | ES2690664T3 (https=) |
| FR (1) | FR2895263B1 (https=) |
| IL (2) | IL192289A (https=) |
| PL (2) | PL2345425T3 (https=) |
| TR (1) | TR201814658T4 (https=) |
| WO (1) | WO2007077365A2 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2895263B1 (fr) | 2005-12-26 | 2008-05-30 | Lab Francais Du Fractionnement | Concentre d'immunoglobines g (lg) appauvri en anticorps anti-a et anti-b, et en igg polyreactives |
| FR2939667B1 (fr) * | 2008-12-17 | 2012-01-27 | Fractionnement Et Des Biotechonologies Lab Franc | Composition d'immunoglobine g comme medicament pour le traitement de l'ictere neonatal par incompatibilite foetomaternelle dans le systeme abo |
| FR2940617B1 (fr) | 2008-12-30 | 2012-04-20 | Fractionnement Et Des Biotechonologies Lab Franc | Composition d'immunoglobulines g |
| EP2236617A1 (en) * | 2009-03-31 | 2010-10-06 | Leukocare Ag | Methods of terminal sterilization of biofunctional compositions |
| FR2949195B1 (fr) | 2009-08-24 | 2011-10-14 | Lfb Biomedicaments | Poche de stockage de solution therapeutique |
| FR2952826B1 (fr) | 2009-11-20 | 2012-04-06 | Lab Francais Du Fractionnement | Utilisation d'immunoglobulines polyvalentes pour traiter une cirrhose hepatique alcoolique ou metabolique |
| CN102892774A (zh) * | 2010-05-05 | 2013-01-23 | 阿尔利克斯公司 | 利用抗体使人类红细胞功能化的方法 |
| FR2959821B1 (fr) | 2010-05-05 | 2012-07-06 | Lab Francais Du Fractionnement | Procede de mesure de l'activation du complement par des igg |
| FR2961107B1 (fr) * | 2010-06-15 | 2012-07-27 | Lab Francais Du Fractionnement | Composition d'immunoglobulines humaines stabilisee |
| FR2962650B1 (fr) * | 2010-07-19 | 2013-04-05 | Lab Francais Du Fractionnement | Composition d'immunoglobulines humaines concentrees |
| FR2974301B1 (fr) | 2011-04-20 | 2013-08-23 | Lab Francais Du Fractionnement | Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes |
| FR2977893B1 (fr) * | 2011-07-11 | 2015-02-20 | Lab Francais Du Fractionnement | Procede de preparation d'un concentre d'immunoglobulines polyvalentes |
| US20140323315A1 (en) | 2013-04-29 | 2014-10-30 | Adimab, Llc | Polyspecificity reagents, methods for their preparation and use |
| MX384222B (es) | 2013-07-05 | 2025-03-14 | Lab Francais Du Fractionnement | Matriz de cromatografia de afinidad. |
| FR3018450B1 (fr) * | 2014-03-11 | 2016-04-15 | Lab Francais Du Fractionnement | Procede de preparation de proteines plasmatiques humaines |
| FR3026950A1 (fr) * | 2014-10-09 | 2016-04-15 | Lab Francais Du Fractionnement | Procede de preparation de plasma universel |
| FR3035799B1 (fr) * | 2015-05-06 | 2017-05-05 | Elicityl | Support pour la purification de liquides biologiques |
| FR3035794B1 (fr) * | 2015-05-06 | 2017-05-05 | Elicityl | Procede pour la purification du sang total ou d'un produit issu du sang |
| FR3035971A1 (fr) * | 2015-05-07 | 2016-11-11 | Lab Francais Du Fractionnement | Composition enrichie en immunoglobulines polyclonales anti-a et/ou anti-b |
| FR3038517B1 (fr) | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
| US20170066839A1 (en) * | 2015-09-08 | 2017-03-09 | Merck Patent Gmbh | Novel affinity chromatography media for removal of anti-a and/or anti-b antibodies |
| US10697982B2 (en) | 2015-09-08 | 2020-06-30 | Merck Patent Gmbh | Methods of evaluating quality of a chromatography media which binds anti-A or anti-B antibodies |
| US10697983B2 (en) | 2015-09-08 | 2020-06-30 | Merck Patent Gmbh | Methods of evaluating quality of media suitable for removing anti-A or anti-B antibodies |
| EP3365365A4 (en) * | 2015-10-21 | 2019-06-19 | Cambryn Biologics, LLC | PROCESS FOR CLEANING PROTEINS FROM PLASMA |
| FR3076294B1 (fr) | 2017-12-29 | 2022-01-28 | Lab Francais Du Fractionnement | Procede de purification d'anticorps a partir de lait brut |
| CN108101981B (zh) * | 2018-01-15 | 2019-06-04 | 四川远大蜀阳药业有限责任公司 | 一种静注免疫球蛋白的生产工艺 |
| CN109239335A (zh) * | 2018-09-11 | 2019-01-18 | 广州万孚生物技术股份有限公司 | 联检试纸条及其制备方法 |
| KR20250161658A (ko) | 2023-03-29 | 2025-11-17 | 체에스엘 베링 아게 | 부작용과 관련된 면역글로불린을 식별하는 방법 |
| AU2024380406A1 (en) | 2023-11-15 | 2026-04-16 | Biotest Ag | Method of manufacturing an igm containing composition |
| WO2026074476A1 (en) | 2024-10-02 | 2026-04-09 | Csl Behring Ag | Method of detecting autoantibodies against fc epsilon receptor i |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR513311A (fr) | 1916-05-04 | 1921-02-12 | Raphael Von Ostrejko | Procédé et installation pour la préparation de charbon décolorant |
| US4664913A (en) | 1982-05-24 | 1987-05-12 | Xoma Corporation | Method for treating plasma for transfusion |
| DK166763B1 (da) | 1983-03-16 | 1993-07-12 | Immuno Ag | Immunoglobulin-g-holdig fraktion |
| US4764369A (en) | 1983-07-14 | 1988-08-16 | New York Blood Center Inc. | Undenatured virus-free biologically active protein derivatives |
| US4946788A (en) * | 1985-06-11 | 1990-08-07 | Ciba-Geigy Corporation | Purified immunoglobulin-related factor, novel monoclonal antibodies, hybridoma cell lines, processes and applications |
| JPS622162A (ja) * | 1985-06-28 | 1987-01-08 | Mutsuo Kitahama | 抗ｂモノクロ−ナル抗体およびその製造法 |
| JPH0662436B2 (ja) | 1986-05-19 | 1994-08-17 | 株式会社ミドリ十字 | 静注用免疫グロブリン製剤の製造方法 |
| AT391810B (de) | 1988-02-26 | 1990-12-10 | Immuno Ag | Verwendung von chymotrypsin zum unwirksammachen des praekallikrein-aktivators |
| DE59009020D1 (de) | 1990-03-22 | 1995-06-08 | Biotest Pharma Gmbh | Verfahren zur Herstellung eines intravenös verträglichen Immunglobulin-G-Präparates. |
| EP0666987A4 (en) * | 1992-10-30 | 1997-08-27 | T Cell Diagnostics Inc | EVALUATION OF THE TOTAL QUANTITY OF A MOLECULE IN A SAMPLE AND METHODS BASED ON SAME. |
| FR2706466B1 (fr) | 1993-06-14 | 1995-08-25 | Aetsrn | Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré. |
| CA2136698A1 (en) | 1994-11-25 | 1996-05-26 | M. Abdul Mazid | Resin compositions and methods for their use |
| US5776711A (en) * | 1996-11-12 | 1998-07-07 | The Regents Of The University Of California | Simultaneous human ABO and RH(D) blood typing or antibody screening by flow cytometry |
| NZ509135A (en) | 1998-06-09 | 2002-10-25 | Statens Seruminstitut | A third generation intravenous immunoglobulin G (IVIG) purified using column chromatographic ion exchange methods |
| AU4860600A (en) * | 1999-06-03 | 2000-12-28 | Advanced Extravascular Systems | One step removal of unwanted molecules from circulating blood |
| FR2794461B1 (fr) | 1999-06-07 | 2004-01-23 | Lab Francais Du Fractionnement | Procede de preparation de nouvelles fractions d'ig humaines possedant une activite immunomodulatrice |
| ATE298889T1 (de) | 1999-10-08 | 2005-07-15 | Vi Technologies Inc | Von isoagglutinin befreite blutzusammensetzungen und verfahren zu ihrer herstellung |
| CA2366469C (en) * | 2000-02-08 | 2010-04-13 | Glycorex Transplantation Ab | Oligosaccharide supports for e.g. removal of antibodies from blood |
| FR2824568B1 (fr) | 2001-05-11 | 2004-04-09 | Lab Francais Du Fractionnement | Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique |
| JP4493882B2 (ja) * | 2001-06-19 | 2010-06-30 | 株式会社カネカ | 抗原およびこの抗原を識別するモノクローナル抗体 |
| US20040101909A1 (en) | 2002-08-20 | 2004-05-27 | Hema-Quebec, 2535 Boul. Laurier, Ste-Foy, Quebec, Canada G1V 4M3 | Purification of polyreactive autoantibodies and uses thereof |
| FR2853551B1 (fr) | 2003-04-09 | 2006-08-04 | Lab Francais Du Fractionnement | Formulation stabilisante pour compositions d'immunoglobulines g sous forme liquide et sous forme lyophilisee |
| FR2895263B1 (fr) | 2005-12-26 | 2008-05-30 | Lab Francais Du Fractionnement | Concentre d'immunoglobines g (lg) appauvri en anticorps anti-a et anti-b, et en igg polyreactives |
-
2005
- 2005-12-26 FR FR0513311A patent/FR2895263B1/fr not_active Expired - Lifetime
-
2006
- 2006-12-26 ES ES11162751.9T patent/ES2690664T3/es active Active
- 2006-12-26 KR KR1020087018476A patent/KR101250095B1/ko active Active
- 2006-12-26 WO PCT/FR2006/002889 patent/WO2007077365A2/fr not_active Ceased
- 2006-12-26 CN CN2012104120215A patent/CN102921004A/zh active Pending
- 2006-12-26 CN CN2006800494486A patent/CN101346153B/zh active Active
- 2006-12-26 EP EP06847150.7A patent/EP1968634B1/fr active Active
- 2006-12-26 ES ES06847150.7T patent/ES2517540T3/es active Active
- 2006-12-26 CN CN201310308621.1A patent/CN103394084B/zh active Active
- 2006-12-26 BR BRPI0620600-0A patent/BRPI0620600B1/pt active IP Right Grant
- 2006-12-26 PL PL11162751T patent/PL2345425T3/pl unknown
- 2006-12-26 CA CA2634997A patent/CA2634997C/en active Active
- 2006-12-26 EP EP20140170934 patent/EP2792366A1/fr not_active Withdrawn
- 2006-12-26 JP JP2008548014A patent/JP5726403B2/ja active Active
- 2006-12-26 AU AU2006334278A patent/AU2006334278B2/en active Active
- 2006-12-26 US US12/159,199 patent/US8153382B2/en active Active
- 2006-12-26 TR TR2018/14658T patent/TR201814658T4/tr unknown
- 2006-12-26 DK DK06847150.7T patent/DK1968634T3/da active
- 2006-12-26 DK DK11162751.9T patent/DK2345425T3/en active
- 2006-12-26 PL PL06847150T patent/PL1968634T3/pl unknown
- 2006-12-26 EP EP11162751.9A patent/EP2345425B1/fr not_active Revoked
-
2008
- 2008-06-18 IL IL192289A patent/IL192289A/en not_active IP Right Cessation
-
2013
- 2013-02-27 JP JP2013036624A patent/JP2013151507A/ja active Pending
-
2014
- 2014-03-30 IL IL231806A patent/IL231806A/en not_active IP Right Cessation
-
2015
- 2015-01-19 JP JP2015007494A patent/JP5944543B2/ja active Active
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