JP2015038155A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015038155A5 JP2015038155A5 JP2014237466A JP2014237466A JP2015038155A5 JP 2015038155 A5 JP2015038155 A5 JP 2015038155A5 JP 2014237466 A JP2014237466 A JP 2014237466A JP 2014237466 A JP2014237466 A JP 2014237466A JP 2015038155 A5 JP2015038155 A5 JP 2015038155A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- beclomethasone
- effective amount
- monopropionate
- active corticosteroid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 12
- 239000003246 corticosteroid Substances 0.000 claims 8
- KUVIULQEHSCUHY-XYWKZLDCSA-N Beclometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)COC(=O)CC)(OC(=O)CC)[C@@]1(C)C[C@@H]2O KUVIULQEHSCUHY-XYWKZLDCSA-N 0.000 claims 5
- 229950000210 beclometasone dipropionate Drugs 0.000 claims 5
- 238000002512 chemotherapy Methods 0.000 claims 4
- 239000002207 metabolite Substances 0.000 claims 4
- 102000003972 Fibroblast growth factor 7 Human genes 0.000 claims 3
- 108090000385 Fibroblast growth factor 7 Proteins 0.000 claims 3
- OHYGPBKGZGRQKT-XGQKBEPLSA-N [(8s,9r,10s,11s,13s,14s,16s,17r)-9-chloro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(OC(=O)CC)[C@@]1(C)C[C@@H]2O OHYGPBKGZGRQKT-XGQKBEPLSA-N 0.000 claims 3
- 229940006003 beclomethasone 17-monopropionate Drugs 0.000 claims 3
- 239000006186 oral dosage form Substances 0.000 claims 3
- 230000005855 radiation Effects 0.000 claims 3
- 238000001959 radiotherapy Methods 0.000 claims 3
- 230000000451 tissue damage Effects 0.000 claims 3
- 231100000827 tissue damage Toxicity 0.000 claims 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 2
- OPNPEZLXXKGRTA-XGQKBEPLSA-N [2-[(8s,9r,10s,11s,13s,14s,16s,17r)-9-chloro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)COC(=O)CC)(O)[C@@]1(C)C[C@@H]2O OPNPEZLXXKGRTA-XGQKBEPLSA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 230000006378 damage Effects 0.000 claims 2
- DEQANNDTNATYII-OULOTJBUSA-N (4r,7s,10s,13r,16s,19r)-10-(4-aminobutyl)-19-[[(2r)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-n-[(2r,3r)-1,3-dihydroxybutan-2-yl]-7-[(1r)-1-hydroxyethyl]-13-(1h-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxa Chemical compound C([C@@H](N)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC=2C3=CC=CC=C3NC=2)NC(=O)[C@H](CC=2C=CC=CC=2)NC1=O)C(=O)N[C@H](CO)[C@H](O)C)C1=CC=CC=C1 DEQANNDTNATYII-OULOTJBUSA-N 0.000 claims 1
- WRGQSWVCFNIUNZ-GDCKJWNLSA-N 1-oleoyl-sn-glycerol 3-phosphate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O WRGQSWVCFNIUNZ-GDCKJWNLSA-N 0.000 claims 1
- 229940093444 Cyclooxygenase 2 inhibitor Drugs 0.000 claims 1
- 102400000921 Gastrin Human genes 0.000 claims 1
- 108010052343 Gastrins Proteins 0.000 claims 1
- 101800001586 Ghrelin Proteins 0.000 claims 1
- 102400000442 Ghrelin-28 Human genes 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 102000004137 Lysophosphatidic Acid Receptors Human genes 0.000 claims 1
- 108090000642 Lysophosphatidic Acid Receptors Proteins 0.000 claims 1
- 108010016076 Octreotide Proteins 0.000 claims 1
- 102100022763 R-spondin-2 Human genes 0.000 claims 1
- 101710110295 R-spondin-2 Proteins 0.000 claims 1
- 102100022766 R-spondin-3 Human genes 0.000 claims 1
- 101710110310 R-spondin-3 Proteins 0.000 claims 1
- 102100022759 R-spondin-4 Human genes 0.000 claims 1
- 101710110307 R-spondin-4 Proteins 0.000 claims 1
- 102000005157 Somatostatin Human genes 0.000 claims 1
- 108010056088 Somatostatin Proteins 0.000 claims 1
- 229930003427 Vitamin E Natural products 0.000 claims 1
- 239000000556 agonist Substances 0.000 claims 1
- AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 claims 1
- 239000005557 antagonist Substances 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 235000006708 antioxidants Nutrition 0.000 claims 1
- 229940092705 beclomethasone Drugs 0.000 claims 1
- NBMKJKDGKREAPL-DVTGEIKXSA-N beclomethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O NBMKJKDGKREAPL-DVTGEIKXSA-N 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 230000005779 cell damage Effects 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- AOXOCDRNSPFDPE-UKEONUMOSA-N chembl413654 Chemical compound C([C@H](C(=O)NCC(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@@H](N)CCC(O)=O)C1=CC=C(O)C=C1 AOXOCDRNSPFDPE-UKEONUMOSA-N 0.000 claims 1
- 239000003255 cyclooxygenase 2 inhibitor Substances 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 230000003013 cytotoxicity Effects 0.000 claims 1
- 231100000135 cytotoxicity Toxicity 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 210000002919 epithelial cell Anatomy 0.000 claims 1
- 210000000981 epithelium Anatomy 0.000 claims 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- GNKDKYIHGQKHHM-RJKLHVOGSA-N ghrelin Chemical compound C([C@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)CN)COC(=O)CCCCCCC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C1=CC=CC=C1 GNKDKYIHGQKHHM-RJKLHVOGSA-N 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 230000000968 intestinal effect Effects 0.000 claims 1
- XGZVUEUWXADBQD-UHFFFAOYSA-L lithium carbonate Chemical compound [Li+].[Li+].[O-]C([O-])=O XGZVUEUWXADBQD-UHFFFAOYSA-L 0.000 claims 1
- 229910052808 lithium carbonate Inorganic materials 0.000 claims 1
- 210000003750 lower gastrointestinal tract Anatomy 0.000 claims 1
- 229960002700 octreotide Drugs 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 210000000813 small intestine Anatomy 0.000 claims 1
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 claims 1
- 229960000553 somatostatin Drugs 0.000 claims 1
- MNQYNQBOVCBZIQ-JQOFMKNESA-A sucralfate Chemical compound O[Al](O)OS(=O)(=O)O[C@@H]1[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](COS(=O)(=O)O[Al](O)O)O[C@H]1O[C@@]1(COS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)O1 MNQYNQBOVCBZIQ-JQOFMKNESA-A 0.000 claims 1
- 229960004291 sucralfate Drugs 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 claims 1
- 235000019165 vitamin E Nutrition 0.000 claims 1
- 229940046009 vitamin E Drugs 0.000 claims 1
- 239000011709 vitamin E Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12078508P | 2008-12-08 | 2008-12-08 | |
| US61/120,785 | 2008-12-08 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011539796A Division JP5709266B2 (ja) | 2008-12-08 | 2009-12-08 | 放射線及び化学療法傷害に用いる局所的に活性なステロイド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015038155A JP2015038155A (ja) | 2015-02-26 |
| JP2015038155A5 true JP2015038155A5 (cg-RX-API-DMAC7.html) | 2015-07-23 |
| JP5905562B2 JP5905562B2 (ja) | 2016-04-20 |
Family
ID=42310112
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011539796A Expired - Fee Related JP5709266B2 (ja) | 2008-12-08 | 2009-12-08 | 放射線及び化学療法傷害に用いる局所的に活性なステロイド |
| JP2014237466A Expired - Fee Related JP5905562B2 (ja) | 2008-12-08 | 2014-11-25 | 放射線及び化学療法傷害に用いる局所的に活性なステロイド |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011539796A Expired - Fee Related JP5709266B2 (ja) | 2008-12-08 | 2009-12-08 | 放射線及び化学療法傷害に用いる局所的に活性なステロイド |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20100183749A1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2902031B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5709266B2 (cg-RX-API-DMAC7.html) |
| KR (2) | KR101783577B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN106692162A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2009333538B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2745930C (cg-RX-API-DMAC7.html) |
| DK (2) | DK2373160T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL213411A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ593694A (cg-RX-API-DMAC7.html) |
| SG (2) | SG10201704531XA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010077681A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010039861A2 (en) | 2008-09-30 | 2010-04-08 | The Regents Of The University Of Michigan | Dendrimer conjugates |
| US9017644B2 (en) | 2008-11-07 | 2015-04-28 | The Regents Of The University Of Michigan | Methods of treating autoimmune disorders and/or inflammatory disorders |
| US9752124B2 (en) | 2009-02-03 | 2017-09-05 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising the stem cells |
| MX2011008044A (es) | 2009-02-03 | 2012-01-12 | Koninklijke Nederlandse Akademie Van Wetenschappen | Medio de cultivo para celulas madre epiteliales y organoides que comprenden las celulas madre. |
| EP2412800A1 (en) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Liver organoid, uses thereof and culture method for obtaining them |
| US8912323B2 (en) | 2009-10-30 | 2014-12-16 | The Regents Of The University Of Michigan | Multifunctional small molecules |
| US9381187B2 (en) * | 2011-02-16 | 2016-07-05 | Paloma Pharmaceuticals, Inc. | Radiation countermeasure agents |
| US9402911B2 (en) | 2011-12-08 | 2016-08-02 | The Regents Of The University Of Michigan | Multifunctional small molecules |
| DK2854850T3 (da) | 2012-05-25 | 2021-08-30 | Sloan Kettering Inst Cancer Res | Sammensætninger til behandling eller forebyggelse af strålingssygdom og gi-syndrom |
| US20160074400A1 (en) * | 2012-08-06 | 2016-03-17 | University Of Southern California | Wnt modulators for the protection, mitigation and treatment of radiation injury |
| WO2014059068A1 (en) * | 2012-10-11 | 2014-04-17 | The Trustees Of The University Of Pennsylvania | Methods for the treatment and prevention of osteoporosis and bone-related disorders |
| US9827290B2 (en) | 2013-02-28 | 2017-11-28 | The Regents Of The University Of Michigan | Compositions and methods relating to induction of intestinal stem cell homeogenesis and/or regeneration |
| WO2015038264A1 (en) | 2013-09-13 | 2015-03-19 | Soligenix, Inc. | Novel peptides and analogs for use in the treatment of oral mucositis |
| US11311598B2 (en) | 2013-09-13 | 2022-04-26 | Soligenix, Inc. | Peptides and analogs for use in the treatment of oral mucositis |
| US9439947B2 (en) | 2014-03-28 | 2016-09-13 | Albert Einstein College Of Medicine, Inc. | Therapy for radiation-induced lung injury |
| JP6865679B2 (ja) * | 2014-10-02 | 2021-04-28 | サイトソーベンツ・コーポレーション | 放射線で誘発された粘膜炎、食道炎、小腸炎、大腸炎、及び胃腸管急性放射線症候群を予防又は治療するための胃腸管投与多孔質消化管吸着剤ポリマーの使用 |
| US20170007559A1 (en) * | 2015-07-12 | 2017-01-12 | The University Of Tennessee Research Foundation | Compositions and methods for protecting colonic epithelial barrier function |
| WO2017119988A2 (en) * | 2015-12-10 | 2017-07-13 | Memorial Sloan Kettering Cancer Center | Radioprotection by wnt activation |
| CN107753932A (zh) * | 2016-08-22 | 2018-03-06 | 中国辐射防护研究院 | Kgf在制备治疗或预防放射性肠炎药物中的用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4661509A (en) * | 1982-09-28 | 1987-04-28 | Gordon Arnold Z | Methods for treating leukopenia |
| US5252333A (en) * | 1987-04-27 | 1993-10-12 | Scotia Holdings Plc | Lithium salt-containing pharmaceutical compositions |
| US6077692A (en) * | 1995-02-14 | 2000-06-20 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 |
| US20030144202A1 (en) * | 1996-10-15 | 2003-07-31 | Amgen Inc. | Uses of keratinocyte growth factor-2 |
| WO2001024812A1 (en) * | 1999-10-06 | 2001-04-12 | N.V. Nutricia | USE OF TRANSFORMING GROWTH FACTOR β AND GROWTH FACTORS IN THE TREATMENT AND PREVENTION OF DISEASES OF THE INTESTINAL MUCOSA |
| US20020086857A1 (en) * | 2000-09-15 | 2002-07-04 | Mcdonald George B. | Method of long-term treatment of graft-versus-host disease using topical active corticosterioids |
| US7544348B2 (en) * | 2001-02-15 | 2009-06-09 | Access Pharmaceuticals, Inc. | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
| US8263582B2 (en) * | 2001-03-15 | 2012-09-11 | Soligenix, Inc. | Method of treating inflammatory disorders of the gastrointestinal tract using topical active corticosteroids |
| NZ554326A (en) * | 2004-12-30 | 2010-10-29 | Soligenix Inc | Beclomethasone dipropionate (BDP) and prednisone for the treatment of graft-versus-host disease resulting from hematopoietic cell transplantation |
| JP4839436B2 (ja) * | 2005-11-02 | 2011-12-21 | 国立大学法人徳島大学 | 消化管粘膜保護剤、カベオリン遺伝子発現促進剤及び抗ストレス剤 |
| US20070293458A1 (en) | 2006-06-16 | 2007-12-20 | Ip-6 Research Inc. | Prevention of nuclear, solar, and other radiation-induced tissue damage |
| WO2008101215A1 (en) * | 2007-02-16 | 2008-08-21 | Varian Medical Systems Technologies, Inc. | Preparative regimen for engraftment, growth and differentiation of non-hematopoeitic cells in vivo |
| HRP20180408T1 (hr) * | 2007-11-13 | 2018-04-20 | Meritage Pharma, Inc. | Pripravci za liječenje gastrointestinalnih upala |
-
2009
- 2009-12-08 KR KR1020167036277A patent/KR101783577B1/ko not_active Expired - Fee Related
- 2009-12-08 NZ NZ593694A patent/NZ593694A/xx not_active IP Right Cessation
- 2009-12-08 WO PCT/US2009/067199 patent/WO2010077681A1/en not_active Ceased
- 2009-12-08 SG SG10201704531XA patent/SG10201704531XA/en unknown
- 2009-12-08 DK DK09836727.9T patent/DK2373160T3/en active
- 2009-12-08 AU AU2009333538A patent/AU2009333538B2/en not_active Ceased
- 2009-12-08 CA CA2745930A patent/CA2745930C/en active Active
- 2009-12-08 EP EP15158919.9A patent/EP2902031B1/en not_active Not-in-force
- 2009-12-08 CN CN201710119024.2A patent/CN106692162A/zh active Pending
- 2009-12-08 SG SG2011041332A patent/SG171997A1/en unknown
- 2009-12-08 KR KR1020117015534A patent/KR20110092351A/ko not_active Ceased
- 2009-12-08 CN CN2009801562821A patent/CN102307466A/zh active Pending
- 2009-12-08 EP EP09836727.9A patent/EP2373160B1/en not_active Not-in-force
- 2009-12-08 JP JP2011539796A patent/JP5709266B2/ja not_active Expired - Fee Related
- 2009-12-08 DK DK15158919.9T patent/DK2902031T3/en active
- 2009-12-08 US US12/633,631 patent/US20100183749A1/en not_active Abandoned
-
2011
- 2011-06-06 IL IL213411A patent/IL213411A/en active IP Right Grant
-
2014
- 2014-11-25 JP JP2014237466A patent/JP5905562B2/ja not_active Expired - Fee Related
-
2017
- 2017-04-24 US US15/495,798 patent/US20170333448A1/en not_active Abandoned
-
2019
- 2019-06-21 US US16/448,526 patent/US20200155571A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015038155A5 (cg-RX-API-DMAC7.html) | ||
| JP2012511034A5 (cg-RX-API-DMAC7.html) | ||
| CA3004028C (en) | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives | |
| HRP20160189T1 (hr) | Liječenje crohnove bolesti lakvinimodom | |
| JP2019528272A5 (cg-RX-API-DMAC7.html) | ||
| NZ624922A (en) | Orally administered corticosteroid compositions | |
| JP2015038135A5 (cg-RX-API-DMAC7.html) | ||
| US20240058353A1 (en) | Methods for treating gi tract disorders | |
| JP2014526503A5 (cg-RX-API-DMAC7.html) | ||
| JP2014528901A5 (cg-RX-API-DMAC7.html) | ||
| JP2018508516A5 (cg-RX-API-DMAC7.html) | ||
| ME02474B (me) | Terapijski režimi | |
| RU2015126661A (ru) | Пероральная комбинация для предотвращения и лечения патологий мочевого пузыря, органов малого таза и мочеполового аппарата | |
| JP6605047B2 (ja) | 疼痛治療のためのセレコキシブの経口用組成物 | |
| SG10201901677YA (en) | Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis | |
| JP2013517304A5 (cg-RX-API-DMAC7.html) | ||
| JP2015516418A5 (cg-RX-API-DMAC7.html) | ||
| JP2013508289A5 (cg-RX-API-DMAC7.html) | ||
| JP2019530706A5 (cg-RX-API-DMAC7.html) | ||
| JP2020500864A5 (cg-RX-API-DMAC7.html) | ||
| FI3706724T3 (fi) | Suun kautta otettavia rifamysiini sv -koostumuksia | |
| RU2018146504A (ru) | Лечение внутрипеченочных холестатических заболеваний | |
| RU2015137612A (ru) | Фармацевтическая дозированная лекарственная форма в виде мягкой желатиновой капсулы, содержащая модифицированную гуаровую камедь | |
| ES2829285T3 (es) | Administración de AINE y composiciones, métodos y sistemas relacionados | |
| JP2012041314A5 (cg-RX-API-DMAC7.html) |