JP2014534227A5 - - Google Patents

Download PDF

Info

Publication number
JP2014534227A5
JP2014534227A5 JP2014540047A JP2014540047A JP2014534227A5 JP 2014534227 A5 JP2014534227 A5 JP 2014534227A5 JP 2014540047 A JP2014540047 A JP 2014540047A JP 2014540047 A JP2014540047 A JP 2014540047A JP 2014534227 A5 JP2014534227 A5 JP 2014534227A5
Authority
JP
Japan
Prior art keywords
compound
moiety
compound according
linker
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014540047A
Other languages
English (en)
Japanese (ja)
Other versions
JP6118808B2 (ja
JP2014534227A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/062850 external-priority patent/WO2013151584A1/en
Publication of JP2014534227A publication Critical patent/JP2014534227A/ja
Publication of JP2014534227A5 publication Critical patent/JP2014534227A5/ja
Application granted granted Critical
Publication of JP6118808B2 publication Critical patent/JP6118808B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014540047A 2011-10-31 2012-10-31 ヒトグリオームを治療するためのmao標的化/探索部分を含む化合物 Expired - Fee Related JP6118808B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161553854P 2011-10-31 2011-10-31
US61/553,854 2011-10-31
PCT/US2012/062850 WO2013151584A1 (en) 2011-10-31 2012-10-31 Compound comprising a mao targeting/ seeker moiety for treating human gliomas

Publications (3)

Publication Number Publication Date
JP2014534227A JP2014534227A (ja) 2014-12-18
JP2014534227A5 true JP2014534227A5 (OSRAM) 2015-11-12
JP6118808B2 JP6118808B2 (ja) 2017-04-19

Family

ID=47146760

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014540047A Expired - Fee Related JP6118808B2 (ja) 2011-10-31 2012-10-31 ヒトグリオームを治療するためのmao標的化/探索部分を含む化合物

Country Status (9)

Country Link
US (1) US10555936B2 (OSRAM)
EP (2) EP2804604A1 (OSRAM)
JP (1) JP6118808B2 (OSRAM)
KR (1) KR102110794B1 (OSRAM)
CN (1) CN104136026B (OSRAM)
AU (1) AU2012376221A1 (OSRAM)
CA (1) CA2887928A1 (OSRAM)
HK (1) HK1204547A1 (OSRAM)
WO (1) WO2013151584A1 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1204547A1 (en) 2011-10-31 2015-11-27 The Methodist Hospital Compound comprising a mao targeting/ seeker moiety for treating human gliomas
CN104710433B (zh) * 2014-01-23 2016-08-17 南京友怡医药科技有限公司 苯丁酸氮芥衍生物、制备方法及应用
US10807944B2 (en) * 2014-04-04 2020-10-20 University Of Florida Research Foundation, Inc. HDAC inhibitor compounds and methods of treatment
JP2024511277A (ja) 2021-02-19 2024-03-13 メビオン・メディカル・システムズ・インコーポレーテッド 粒子線治療システムのためのガントリー

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4913891A (en) * 1986-04-17 1990-04-03 The United States Of America As Represented By The United States Department Of Energy Positron emitter labeled enzyme inhibitors
US5466468A (en) 1990-04-03 1995-11-14 Ciba-Geigy Corporation Parenterally administrable liposome formulation comprising synthetic lipids
US5399363A (en) 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
CA2164518A1 (en) * 1993-06-07 1994-12-22 Cristopher D.V. Black Immunoreactive reagents employing monoamine oxidase
US5543158A (en) 1993-07-23 1996-08-06 Massachusetts Institute Of Technology Biodegradable injectable nanoparticles
IE80468B1 (en) 1995-04-04 1998-07-29 Elan Corp Plc Controlled release biodegradable nanoparticles containing insulin
US5612329A (en) 1995-06-05 1997-03-18 University Of Maryland At Baltimore Diaziridinylpolyamine anti-cancer agents
WO1998022110A1 (en) * 1996-11-20 1998-05-28 Virginia Tech Intellectual Properties, Inc. Prodrugs for the selective inhibition of monoamine oxidase-b
IL145089A0 (en) 1999-03-03 2002-06-30 Procter & Gamble Alkenyl-and alkynyl-containing metalloprotease inhibitors
US6750345B2 (en) 2000-11-07 2004-06-15 Symyx Technologies, Inc. Substituted pyridyl amine catalysts, complexes and compositions
US6946479B2 (en) 2002-11-09 2005-09-20 The Procter & Gamble Company N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones
WO2004110255A2 (en) 2003-06-09 2004-12-23 Gang Zheng Antineoplastic agents targeted via glut transporters
EP1758887A1 (en) * 2004-05-14 2007-03-07 Pfizer Products Incorporated Pyrimidine derivatives for the treatment of abnormal cell growth
US7091205B2 (en) 2004-10-08 2006-08-15 Yu Show Fu Use of tetramethylpyrazine in the treatment of brain tumor
GB0513297D0 (en) 2005-06-29 2005-08-03 Glaxo Group Ltd Novel compounds
US20070275944A1 (en) 2006-04-05 2007-11-29 The Board Of Trustees Operating Michigan State University Antioxidants and methods of their use
AR070317A1 (es) * 2008-02-06 2010-03-31 Osi Pharm Inc Furo (3,2-c) piridina y tieno (3,2-c) piridinas
WO2009111278A2 (en) * 2008-02-29 2009-09-11 Array Biopharma Inc. Raf inhibitor compounds and methods of use thereof
EP2141163A1 (de) * 2008-07-02 2010-01-06 Bayer Schering Pharma AG Substituierte Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel
EP3613729A1 (en) * 2009-06-10 2020-02-26 Chugai Seiyaku Kabushiki Kaisha Tetracyclic compounds
WO2011035332A1 (en) * 2009-09-21 2011-03-24 Chemocentryx, Inc. Pyrrolidinone carboxamide derivatives as chemerin-r ( chemr23 ) modulators
HK1204547A1 (en) 2011-10-31 2015-11-27 The Methodist Hospital Compound comprising a mao targeting/ seeker moiety for treating human gliomas

Similar Documents

Publication Publication Date Title
KR102123365B1 (ko) 항박테리아 치료제 및 예방제
JP6352244B2 (ja) 骨格筋疲労に対する耐性を向上させるための方法
US20170157168A1 (en) Prevention of gastric ulcer by carbon monoxide
JP2011529474A (ja) cdk阻害剤および抗悪性腫瘍剤を含む治療用組合せ
JP2010523696A (ja) 脳腫瘍を治療する方法
TW201244714A (en) PARP inhibitors for the treatment of CIPN
WO2008131024A1 (en) Iodo-hexose compounds useful to treat cancer
US20200179417A1 (en) Combination chemotherapies
JP2014534227A5 (OSRAM)
US11224608B2 (en) Compounds and methods for treating cancer
RU2011151861A (ru) Оксазолидинонсодержащие димерные соединения, композиции и способы их получения и использования
JP2013504590A (ja) 非放射性リン脂質化合物、組成物、及び使用方法
EP3011972A1 (en) Medicinal composition for promoting synthesis of protoporphyrin ix
TW201309298A (zh) 治療惡性神經膠質瘤之醫藥組合物
Friedman et al. Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts
JP2019523783A (ja) がんの治療に有用なポルフィリン化合物及び組成物
US10774063B2 (en) Materials and method for inhibiting replication protein A and uses thereof
CN104136026B (zh) 包含mao靶向/探寻器部分的人神经胶质瘤治疗用化合物
AU2017235350B2 (en) Combination therapy for proliferative diseases
WO2018222134A1 (en) Cancer therapy
CA3115103A1 (en) Pi3k inhibitors and uses thereof
US20100087398A1 (en) Dihydropyridine derivative for treating cancer or a pre-cancerous condition and other conditions
RU2639819C2 (ru) Композиция, ингибирующая теломеразу
KR20230147351A (ko) 퀴녹살린 카르복스아마이드 유도체 및 이를 유효성분으로 포함하는 교모세포종의 예방 또는 치료용 약학적 조성물
CN118119611A (zh) 用于降解dot1l的小分子及其用途