JP2014531449A

JP2014531449A - キナーゼ阻害剤としてのピラゾロ［４，３―ｃ］ピリジン誘導体

キナーゼ阻害剤としてのピラゾロ［４，３―ｃ］ピリジン誘導体 Download PDF

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Publication number: JP2014531449A
Authority: JP; Japan
Prior art keywords: alkyl; alkenyl; methyl; alkynyl; substituted
Prior art date: 2011-09-20
Legal status : Pending

Application number

JP2014531222A

Other languages

English (en)

Japanese (ja)

Other versions

JP2014531449A5 (OSRAM

Inventor

ナイジェル、ラムスデン

クラウディオ、ダゴースティン

Original Assignee

セルゾームリミティッド

Priority date

2011-09-20

Filing date

2012-09-20

Publication date

2014-11-27

2012-09-20 Application filed by セルゾームリミティッド, セルゾームリミティッド filed Critical セルゾームリミティッド

2014-11-27 Publication of JP2014531449A publication Critical patent/JP2014531449A/ja

2015-11-05 Publication of JP2014531449A5 publication Critical patent/JP2014531449A5/ja

Status Pending legal-status Critical Current

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229940043355 kinase inhibitor Drugs 0.000 title abstract description 7
239000003757 phosphotransferase inhibitor Substances 0.000 title abstract description 7
WCXFPLXZZSWROM-UHFFFAOYSA-N 1h-pyrazolo[4,3-c]pyridine Chemical class C1=NC=C2C=NNC2=C1 WCXFPLXZZSWROM-UHFFFAOYSA-N 0.000 title 1
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125000000882 C2-C6 alkenyl group Chemical group 0.000 claims description 52
125000003601 C2-C6 alkynyl group Chemical group 0.000 claims description 50
229910052736 halogen Inorganic materials 0.000 claims description 45
238000000034 method Methods 0.000 claims description 42
229910052799 carbon Inorganic materials 0.000 claims description 40
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125000000623 heterocyclic group Chemical group 0.000 claims description 31
229910052757 nitrogen Inorganic materials 0.000 claims description 31
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ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical group C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 claims description 5
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